Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

Cancer Letters

Volumn 291, Issue 1, 2010, Pages 20-30

  Chen, Ying Ju ^a   Wu, Chien Lin ^b   Liu, Ju Fang ^c   Fong, Yi Chin ^c,d   Hsu, Sheng Feng ^c   Li, Te Mao ^c   Su, Yi Chang ^c   Liu, Shing Hwa ^a   Tang, Chih Hsin ^c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Chondrosarcoma; ER; GRP78; Honokiol

Indexed keywords

CALCIUM; CALPAIN; GLUCOSE REGULATED PROTEIN 78; HONOKIOL; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL XL; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER SIZE; CARTILAGE CELL; CHONDROSARCOMA; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAGNOLIA OFFICINALIS; MAGNOLIACEAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA CELL; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BIPHENYL COMPOUNDS; BONE NEOPLASMS; CALCIUM; CALPAIN; CELL LINE, TUMOR; CHONDROSARCOMA; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HUMANS; LIGNANS; MALE; MICE; MICE, INBRED BALB C; MITOCHONDRIA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA; MAGNOLIA OFFICINALIS;

EID: 77949874077     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.08.032     Document Type: Article

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