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Volumn 14, Issue 5, 2014, Pages

B cell biology: An overview topical collection on basic and applied science

Author keywords

B cell; Biology; GC reaction; Memory B cells; Plasma cells; T cells

Indexed keywords

B LYMPHOCYTE RECEPTOR; DNA; ANTIGEN; TRANSCRIPTION FACTOR;

EID: 84898807636     PISSN: 15297322     EISSN: 15346315     Source Type: Journal    
DOI: 10.1007/s11882-014-0434-8     Document Type: Article
Times cited : (58)

References (177)
  • 1
    • 0342437514 scopus 로고    scopus 로고
    • B-cell development: A comparison between mouse and man
    • 1:CAS:528:DyaK1cXmsVakur8%3D
    • Ghia P, ten Boekel E, Rolink AG, Melchers F. B-cell development: a comparison between mouse and man. Immunol Today. 1998;19:480-5.
    • (1998) Immunol Today , vol.19 , pp. 480-485
    • Ghia, P.1    Ten Boekel, E.2    Rolink, A.G.3    Melchers, F.4
  • 2
    • 84876532900 scopus 로고    scopus 로고
    • Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation
    • 1:CAS:528:DC%2BC3sXksVGqtb8%3D
    • Ferreiros-Vidal I et al. Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation. Blood. 2013;121:1769-82.
    • (2013) Blood , vol.121 , pp. 1769-1782
    • Ferreiros-Vidal, I.1
  • 3
    • 0036519296 scopus 로고    scopus 로고
    • Haematopoietic cell-fate decisions, chromatin regulation and ikaros
    • 1:CAS:528:DC%2BD38XisFaktbw%3D
    • Georgopoulos K. Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nat Rev Immunol. 2002;2:162-74.
    • (2002) Nat Rev Immunol , vol.2 , pp. 162-174
    • Georgopoulos, K.1
  • 4
    • 33645109285 scopus 로고    scopus 로고
    • Early hematopoietic lineage restrictions directed by Ikaros
    • 1:CAS:528:DC%2BD28Xis1Gmtbc%3D
    • Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nat Immunol. 2006;7:382-91.
    • (2006) Nat Immunol , vol.7 , pp. 382-391
    • Yoshida, T.1    Ng, S.Y.2    Zuniga-Pflucker, J.C.3    Georgopoulos, K.4
  • 5
    • 33947153094 scopus 로고    scopus 로고
    • Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits
    • 1:CAS:528:DC%2BD2sXjvVSns7k%3D
    • Thompson EC et al. Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity. 2007;26:335-44.
    • (2007) Immunity , vol.26 , pp. 335-344
    • Thompson, E.C.1
  • 6
    • 77956630164 scopus 로고    scopus 로고
    • Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression
    • 1:CAS:528:DC%2BC3cXhtFyhtrbK
    • Ma S et al. Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression. Mol Cell Biol. 2010;30:4149-58.
    • (2010) Mol Cell Biol , vol.30 , pp. 4149-4158
    • Ma, S.1
  • 7
    • 0033582324 scopus 로고    scopus 로고
    • Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia
    • 1:CAS:528:DyaK1MXmtlCrsw%3D%3D
    • Sun L et al. Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 1999;96:680-5.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 680-685
    • Sun, L.1
  • 8
    • 84874647204 scopus 로고    scopus 로고
    • The genomic landscape of hypodiploid acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3sXhtV2qsrw%3D This extensive genomic profiling approach to ALL reports chromosomal alterations linked to Ras, Ikaros and TP53
    • Holmfeldt L et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet. 2013;45:242-52. This extensive genomic profiling approach to ALL reports chromosomal alterations linked to Ras, Ikaros and TP53.
    • (2013) Nat Genet , vol.45 , pp. 242-252
    • Holmfeldt, L.1
  • 9
    • 0028019274 scopus 로고
    • The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins
    • 1:CAS:528:DyaK2MXisVWgur4%3D
    • Molnar A, Georgopoulos K. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Mol Cell Biol. 1994;14:8292-303.
    • (1994) Mol Cell Biol , vol.14 , pp. 8292-8303
    • Molnar, A.1    Georgopoulos, K.2
  • 10
    • 0038106526 scopus 로고    scopus 로고
    • Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
    • 1:CAS:528:DC%2BD3sXlvVOrs7w%3D
    • Papathanasiou P et al. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity. 2003;19:131-44.
    • (2003) Immunity , vol.19 , pp. 131-144
    • Papathanasiou, P.1
  • 11
    • 84886656087 scopus 로고    scopus 로고
    • Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros
    • 1:CAS:528:DC%2BC3sXhtl2ksbrP The authors demonstrate distinct roles of individual Ikaros Zn-fingers in gene regulation
    • Schjerven H et al. Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol. 2013;14:1073-83. The authors demonstrate distinct roles of individual Ikaros Zn-fingers in gene regulation.
    • (2013) Nat Immunol , vol.14 , pp. 1073-1083
    • Schjerven, H.1
  • 12
    • 0033103374 scopus 로고    scopus 로고
    • Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
    • 1:CAS:528:DyaK1MXitlamurg%3D
    • Kim J et al. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity. 1999;10:345-55.
    • (1999) Immunity , vol.10 , pp. 345-355
    • Kim, J.1
  • 13
    • 83855160775 scopus 로고    scopus 로고
    • Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis
    • 1:CAS:528:DC%2BC3MXhsVKjsb%2FL The paper describes how Ikaros regulates nucleosome remodeling and histone modification
    • Zhang J et al. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol. 2012;13:86-94. The paper describes how Ikaros regulates nucleosome remodeling and histone modification.
    • (2012) Nat Immunol , vol.13 , pp. 86-94
    • Zhang, J.1
  • 14
    • 23444459544 scopus 로고
    • Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells
    • 1:CAS:528:DyaK2cXksFals7w%3D
    • Turner Jr CA, Mack DH, Davis MM. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin- secreting cells. Cell. 1994;77:297-306.
    • (1994) Cell , vol.77 , pp. 297-306
    • Turner, Jr.C.A.1    Mack, D.H.2    Davis, M.M.3
  • 15
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • 1:CAS:528:DyaK2sXjs1ahsLo%3D
    • Ye BH et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet. 1997;16:161-70.
    • (1997) Nat Genet , vol.16 , pp. 161-170
    • Ye, B.H.1
  • 16
    • 10344247666 scopus 로고    scopus 로고
    • The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
    • 1:CAS:528:DC%2BD2cXhtVeht7rE
    • Phan RT, Dalla-Favera R. The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature. 2004;432:635-9.
    • (2004) Nature , vol.432 , pp. 635-639
    • Phan, R.T.1    Dalla-Favera, R.2
  • 17
    • 78650170140 scopus 로고    scopus 로고
    • Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation
    • 1:CAS:528:DC%2BC3cXhsFyisLrI
    • Kosan C et al. Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation. Immunity. 2010;33:917-28.
    • (2010) Immunity , vol.33 , pp. 917-928
    • Kosan, C.1
  • 18
    • 82555164922 scopus 로고    scopus 로고
    • Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
    • Moroy T, Khandanpour C. Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation. Semin Immunol. 2011;23:368-78.
    • (2011) Semin Immunol , vol.23 , pp. 368-378
    • Moroy, T.1    Khandanpour, C.2
  • 19
    • 80755180849 scopus 로고    scopus 로고
    • The DNA-binding protein CTCF limits proximal Vkappa recombination and restricts kappa enhancer interactions to the immunoglobulin kappa light chain locus
    • de Almeida Ribeiro C et al. The DNA-binding protein CTCF limits proximal Vkappa recombination and restricts kappa enhancer interactions to the immunoglobulin kappa light chain locus. Immunity. 2011;35:501-13.
    • (2011) Immunity , vol.35 , pp. 501-513
    • De Almeida Ribeiro, C.1
  • 20
    • 34250212629 scopus 로고    scopus 로고
    • The transcriptional regulation of B cell lineage commitment
    • 1:CAS:528:DC%2BD2sXntlKnur0%3D
    • Nutt SL, Kee BL. The transcriptional regulation of B cell lineage commitment. Immunity. 2007;26:715-25.
    • (2007) Immunity , vol.26 , pp. 715-725
    • Nutt, S.L.1    Kee, B.L.2
  • 21
    • 17044440153 scopus 로고    scopus 로고
    • Contingent gene regulatory networks and B cell fate specification
    • 1:CAS:528:DC%2BD2MXjsFemsbo%3D
    • Singh H, Medina KL, Pongubala JM. Contingent gene regulatory networks and B cell fate specification. Proc Natl Acad Sci U S A. 2005;102:4949-53.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4949-4953
    • Singh, H.1    Medina, K.L.2    Pongubala, J.M.3
  • 22
    • 84880780575 scopus 로고    scopus 로고
    • Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells
    • 1:CAS:528:DC%2BC3sXhtVaktb7P The paper shows that EBF1 and Pax5 induce lineage commitment by repressing alternative cell fates
    • Nechanitzky R et al. Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nat Immunol. 2013;14:867-75. The paper shows that EBF1 and Pax5 induce lineage commitment by repressing alternative cell fates.
    • (2013) Nat Immunol , vol.14 , pp. 867-875
    • Nechanitzky, R.1
  • 23
    • 29144482740 scopus 로고    scopus 로고
    • E47 is required for V(D)J recombinase activity in common lymphoid progenitors
    • 1:CAS:528:DC%2BD2MXhtlCjsrjI
    • Borghesi L et al. E47 is required for V(D)J recombinase activity in common lymphoid progenitors. J Exp Med. 2005;202:1669-77.
    • (2005) J Exp Med , vol.202 , pp. 1669-1677
    • Borghesi, L.1
  • 24
    • 0029045161 scopus 로고
    • Failure of B-cell differentiation in mice lacking the transcription factor EBF
    • 1:CAS:528:DyaK2MXntFSmu7s%3D
    • Lin H, Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature. 1995;376:263-7.
    • (1995) Nature , vol.376 , pp. 263-267
    • Lin, H.1    Grosschedl, R.2
  • 25
    • 79959562288 scopus 로고    scopus 로고
    • B Lymphocyte commitment program is driven by the proto-oncogene c-Myc
    • 1:CAS:528:DC%2BC3MXntVGnt70%3D
    • Vallespinos M et al. B Lymphocyte commitment program is driven by the proto-oncogene c-Myc. J Immunol. 2011;186:6726-36.
    • (2011) J Immunol , vol.186 , pp. 6726-6736
    • Vallespinos, M.1
  • 26
    • 84864297177 scopus 로고    scopus 로고
    • Runx1-Cbfbeta facilitates early B lymphocyte development by regulating expression of Ebf1
    • 1:CAS:528:DC%2BC38XhtVegtrfL
    • Seo W, Ikawa T, Kawamoto H, Taniuchi I. Runx1-Cbfbeta facilitates early B lymphocyte development by regulating expression of Ebf1. J Exp Med. 2012;209:1255-62.
    • (2012) J Exp Med , vol.209 , pp. 1255-1262
    • Seo, W.1    Ikawa, T.2    Kawamoto, H.3    Taniuchi, I.4
  • 27
    • 77953763449 scopus 로고    scopus 로고
    • A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
    • 1:CAS:528:DC%2BC3cXntlSjtrc%3D
    • Lin YC et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol. 2010;11:635-43.
    • (2010) Nat Immunol , vol.11 , pp. 635-643
    • Lin, Y.C.1
  • 28
    • 51549083884 scopus 로고    scopus 로고
    • EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors
    • 1:CAS:528:DC%2BD1cXhtVSiu7nE
    • Zandi S et al. EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors. J Immunol. 2008;181:3364-72.
    • (2008) J Immunol , vol.181 , pp. 3364-3372
    • Zandi, S.1
  • 29
    • 82555179207 scopus 로고    scopus 로고
    • B-lymphocyte commitment: Identifying the point of no return
    • 1:CAS:528:DC%2BC3MXhsVOrurzJ
    • Welinder E, Ahsberg J, Sigvardsson M. B-lymphocyte commitment: identifying the point of no return. Semin Immunol. 2011;23:335-40.
    • (2011) Semin Immunol , vol.23 , pp. 335-340
    • Welinder, E.1    Ahsberg, J.2    Sigvardsson, M.3
  • 30
    • 56349127778 scopus 로고    scopus 로고
    • Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
    • 1:CAS:528:DC%2BD1cXhtlOjsb3I
    • Dengler HS et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008;9:1388-98.
    • (2008) Nat Immunol , vol.9 , pp. 1388-1398
    • Dengler, H.S.1
  • 31
    • 0033533891 scopus 로고    scopus 로고
    • Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
    • 1:CAS:528:DyaK1MXmvFCntbs%3D
    • Nutt SL, Heavey B, Rolink AG, Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999;401:556-62.
    • (1999) Nature , vol.401 , pp. 556-562
    • Nutt, S.L.1    Heavey, B.2    Rolink, A.G.3    Busslinger, M.4
  • 32
    • 0034994533 scopus 로고    scopus 로고
    • Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis
    • 1:CAS:528:DC%2BD3MXjvFOnt7Y%3D
    • Nutt SL, Eberhard D, Horcher M, Rolink AG, Busslinger M. Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis. Int Rev Immunol. 2001;20:65-82.
    • (2001) Int Rev Immunol , vol.20 , pp. 65-82
    • Nutt, S.L.1    Eberhard, D.2    Horcher, M.3    Rolink, A.G.4    Busslinger, M.5
  • 33
    • 33644978463 scopus 로고    scopus 로고
    • Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells
    • 1:CAS:528:DC%2BD28XjtlKmsL8%3D
    • Delogu A et al. Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity. 2006;24:269-81.
    • (2006) Immunity , vol.24 , pp. 269-281
    • Delogu, A.1
  • 34
    • 34247188078 scopus 로고    scopus 로고
    • Pax5: The guardian of B cell identity and function
    • 1:CAS:528:DC%2BD2sXkt1KhsbY%3D
    • Cobaleda C, Schebesta A, Delogu A, Busslinger M. Pax5: the guardian of B cell identity and function. Nat Immunol. 2007;8:463-70.
    • (2007) Nat Immunol , vol.8 , pp. 463-470
    • Cobaleda, C.1    Schebesta, A.2    Delogu, A.3    Busslinger, M.4
  • 35
    • 0036906546 scopus 로고    scopus 로고
    • Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1
    • 1:CAS:528:DC%2BD38XpvVWgsb4%3D
    • Souabni A, Cobaleda C, Schebesta M, Busslinger M. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity. 2002;17:781-93.
    • (2002) Immunity , vol.17 , pp. 781-793
    • Souabni, A.1    Cobaleda, C.2    Schebesta, M.3    Busslinger, M.4
  • 36
    • 0037528814 scopus 로고    scopus 로고
    • Human cord blood CD34+Pax-5+ B-cell progenitors: Single-cell analyses of their gene expression profiles
    • 1:CAS:528:DC%2BD3sXjs1aqsL4%3D
    • Sanz E, Alvarez-Mon M, Martinez AC, de la Hera A. Human cord blood CD34+Pax-5+ B-cell progenitors: single-cell analyses of their gene expression profiles. Blood. 2003;101:3424-30.
    • (2003) Blood , vol.101 , pp. 3424-3430
    • Sanz, E.1    Alvarez-Mon, M.2    Martinez, A.C.3    De La Hera, A.4
  • 37
    • 0038481245 scopus 로고    scopus 로고
    • In vitro identification of human pro-B cells that give rise to macrophages, natural killer cells, and T cells
    • 1:CAS:528:DC%2BD3sXktFKhtL0%3D
    • Reynaud D, Lefort N, Manie E, Coulombel L, Levy Y. In vitro identification of human pro-B cells that give rise to macrophages, natural killer cells, and T cells. Blood. 2003;101:4313-21.
    • (2003) Blood , vol.101 , pp. 4313-4321
    • Reynaud, D.1    Lefort, N.2    Manie, E.3    Coulombel, L.4    Levy, Y.5
  • 38
    • 27144461642 scopus 로고    scopus 로고
    • Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression
    • van Zelm MC et al. Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression. J Immunol. 2005;175:5912-22.
    • (2005) J Immunol , vol.175 , pp. 5912-5922
    • Van Zelm, M.C.1
  • 39
    • 0027320217 scopus 로고
    • The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1
    • 1:CAS:528:DyaK2cXisVGltQ%3D%3D
    • Puck JM et al. The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1. Hum Mol Genet. 1993;2:1099-104.
    • (1993) Hum Mol Genet , vol.2 , pp. 1099-1104
    • Puck, J.M.1
  • 40
    • 0029812552 scopus 로고    scopus 로고
    • Interleukin 7 independent development of human B cells
    • 1:STN:280:DyaK28vhtlKnuw%3D%3D
    • Prieyl JA, LeBien TW. Interleukin 7 independent development of human B cells. Proc Natl Acad Sci U S A. 1996;93:10348-53.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10348-10353
    • Prieyl, J.A.1    Lebien, T.W.2
  • 41
    • 0031740732 scopus 로고    scopus 로고
    • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
    • 1:CAS:528:DyaK1cXnslOlsrw%3D
    • Puel A, Ziegler SF, Buckley RH, Leonard WJ. Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet. 1998;20:394-7.
    • (1998) Nat Genet , vol.20 , pp. 394-397
    • Puel, A.1    Ziegler, S.F.2    Buckley, R.H.3    Leonard, W.J.4
  • 42
    • 0025027433 scopus 로고
    • Phenotypic features and proliferative activity of B cell progenitors in X-linked agammaglobulinemia
    • 1:STN:280:DyaK3czmtFyltA%3D%3D
    • Campana D, Farrant J, Inamdar N, Webster AD, Janossy G. Phenotypic features and proliferative activity of B cell progenitors in X-linked agammaglobulinemia. J Immunol. 1990;145:1675-80.
    • (1990) J Immunol , vol.145 , pp. 1675-1680
    • Campana, D.1    Farrant, J.2    Inamdar, N.3    Webster, A.D.4    Janossy, G.5
  • 43
    • 0027399081 scopus 로고
    • Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
    • 1:CAS:528:DyaK3sXkvFensro%3D
    • Tsukada S et al. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell. 1993;72:279-90.
    • (1993) Cell , vol.72 , pp. 279-290
    • Tsukada, S.1
  • 44
    • 0033521148 scopus 로고    scopus 로고
    • An essential role for BLNK in human B cell development
    • 1:CAS:528:DyaK1MXnvFSiu7Y%3D
    • Minegishi Y et al. An essential role for BLNK in human B cell development. Science. 1999;286:1954-7.
    • (1999) Science , vol.286 , pp. 1954-1957
    • Minegishi, Y.1
  • 46
    • 0031753237 scopus 로고    scopus 로고
    • Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain
    • 1:CAS:528:DyaK1cXnvFOisL4%3D
    • Goldman JP et al. Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain. Br J Haematol. 1998;103:335-42.
    • (1998) Br J Haematol , vol.103 , pp. 335-342
    • Goldman, J.P.1
  • 47
    • 0032190418 scopus 로고    scopus 로고
    • Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells
    • van der Loo JC et al. Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells. Blood. 1998;92:2556-70.
    • (1998) Blood , vol.92 , pp. 2556-2570
    • Van Der Loo, J.C.1
  • 48
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • 1:CAS:528:DyaK1MXhtFSgtbY%3D
    • Peled A et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science. 1999;283:845-8.
    • (1999) Science , vol.283 , pp. 845-848
    • Peled, A.1
  • 49
    • 0034041388 scopus 로고    scopus 로고
    • Hematopoietic repopulating ability of cord blood CD34(+) cells in NOD/Shi-scid mice
    • 1:STN:280:DC%2BD3czgtVKnug%3D%3D
    • Ueda T et al. Hematopoietic repopulating ability of cord blood CD34(+) cells in NOD/Shi-scid mice. Stem Cells. 2000;18:204-13.
    • (2000) Stem Cells , vol.18 , pp. 204-213
    • Ueda, T.1
  • 50
    • 0037039361 scopus 로고    scopus 로고
    • Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice
    • 1:CAS:528:DC%2BD38Xlt1Cktw%3D%3D
    • Hogan CJ, Shpall EJ, Keller G. Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice. Proc Natl Acad Sci U S A. 2002;99:413-8.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 413-418
    • Hogan, C.J.1    Shpall, E.J.2    Keller, G.3
  • 51
    • 18344410760 scopus 로고    scopus 로고
    • NOD/SCID/gamma(c)(null) mouse: An excellent recipient mouse model for engraftment of human cells
    • 1:CAS:528:DC%2BD38XosVSisLg%3D
    • Ito M et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood. 2002;100:3175-82.
    • (2002) Blood , vol.100 , pp. 3175-3182
    • Ito, M.1
  • 52
    • 1842588698 scopus 로고    scopus 로고
    • Development of a human adaptive immune system in cord blood cell-transplanted mice
    • 1:CAS:528:DC%2BD2cXis1ansLY%3D
    • Traggiai E et al. Development of a human adaptive immune system in cord blood cell-transplanted mice. Science. 2004;304:104-7.
    • (2004) Science , vol.304 , pp. 104-107
    • Traggiai, E.1
  • 53
    • 27144556922 scopus 로고    scopus 로고
    • Dengue fever in humanized NOD/SCID mice
    • 1:CAS:528:DC%2BD2MXhtFOhs7vO
    • Bente DA, Melkus MW, Garcia JV, Rico-Hesse R. Dengue fever in humanized NOD/SCID mice. J Virol. 2005;79:13797-9.
    • (2005) J Virol , vol.79 , pp. 13797-13799
    • Bente, D.A.1    Melkus, M.W.2    Garcia, J.V.3    Rico-Hesse, R.4
  • 54
    • 33947356676 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice
    • 1:CAS:528:DC%2BD2sXjt1Grsbo%3D
    • Gorantla S et al. Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice. J Virol. 2007;81:2700-12.
    • (2007) J Virol , vol.81 , pp. 2700-2712
    • Gorantla, S.1
  • 55
    • 55749106054 scopus 로고    scopus 로고
    • Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines
    • 1:CAS:528:DC%2BD1cXhtlCntrvI
    • Yu CI et al. Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines. Blood. 2008;112:3671-8.
    • (2008) Blood , vol.112 , pp. 3671-3678
    • Yu, C.I.1
  • 56
    • 77349096116 scopus 로고    scopus 로고
    • Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice
    • 1:CAS:528:DC%2BC3cXksFOhsL4%3D
    • Banerjee P et al. Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice. Blood. 2010;115:2640-8.
    • (2010) Blood , vol.115 , pp. 2640-2648
    • Banerjee, P.1
  • 57
    • 80052938981 scopus 로고    scopus 로고
    • Efficient differentiation and function of human macrophages in humanized CSF-1 mice
    • 1:CAS:528:DC%2BC3MXht1Ogtb3N
    • Rathinam C et al. Efficient differentiation and function of human macrophages in humanized CSF-1 mice. Blood. 2011;118:3119-28.
    • (2011) Blood , vol.118 , pp. 3119-3128
    • Rathinam, C.1
  • 58
    • 84865442525 scopus 로고    scopus 로고
    • Full reconstitution of human platelets in humanized mice after macrophage depletion
    • 1:CAS:528:DC%2BC38Xhtlalu77N
    • Hu Z, Yang YG. Full reconstitution of human platelets in humanized mice after macrophage depletion. Blood. 2012;120:1713-6.
    • (2012) Blood , vol.120 , pp. 1713-1716
    • Hu, Z.1    Yang, Y.G.2
  • 59
    • 84862596451 scopus 로고    scopus 로고
    • Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2rgammaKO mice
    • 1:CAS:528:DC%2BC38XotFGru7o%3D
    • Tanaka S et al. Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2rgammaKO mice. J Immunol. 2012;188:6145-55.
    • (2012) J Immunol , vol.188 , pp. 6145-6155
    • Tanaka, S.1
  • 60
    • 84893374134 scopus 로고    scopus 로고
    • A feeder free differentiation system identifies autonomously proliferating B cell precursors in human bone marrow
    • 1:CAS:528:DC%2BC2cXhtFKktLs%3D This paper reports a feeder cell-free differentiation system for human B cells and autonomous proliferation of human pro-B and pre-B cells. The paper reports autonomous development and proliferation of human B cell precursors
    • Kraus H et al. A feeder free differentiation system identifies autonomously proliferating B cell precursors in human bone marrow. J Immunol. 2014;192(3):1044-54. This paper reports a feeder cell-free differentiation system for human B cells and autonomous proliferation of human pro-B and pre-B cells. The paper reports autonomous development and proliferation of human B cell precursors.
    • (2014) J Immunol , vol.192 , Issue.3 , pp. 1044-1054
    • Kraus, H.1
  • 61
    • 0028968187 scopus 로고
    • Long-term culture system for selective growth of human B-cell progenitors
    • 1:CAS:528:DyaK2MXktFWkurY%3D
    • Rawlings DJ, Quan SG, Kato RM, Witte ON. Long-term culture system for selective growth of human B-cell progenitors. Proc Natl Acad Sci U S A. 1995;92:1570-4.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1570-1574
    • Rawlings, D.J.1    Quan, S.G.2    Kato, R.M.3    Witte, O.N.4
  • 62
    • 17444370886 scopus 로고    scopus 로고
    • In vitro reconstitution of human B-cell ontogeny: From CD34(+) multipotent progenitors to Ig-secreting cells
    • 1:STN:280:DyaK1M%2FmtFOltA%3D%3D
    • Fluckiger AC et al. In vitro reconstitution of human B-cell ontogeny: from CD34(+) multipotent progenitors to Ig-secreting cells. Blood. 1998;92:4509-20.
    • (1998) Blood , vol.92 , pp. 4509-4520
    • Fluckiger, A.C.1
  • 63
    • 0032800455 scopus 로고    scopus 로고
    • Comparative studies of different stromal cell microenvironments in support of human B-cell development
    • 1:STN:280:DyaK1MzlsFCmug%3D%3D
    • Kurosaka D, LeBien TW, Pribyl JA. Comparative studies of different stromal cell microenvironments in support of human B-cell development. Exp Hematol. 1999;27:1271-81.
    • (1999) Exp Hematol , vol.27 , pp. 1271-1281
    • Kurosaka, D.1    Lebien, T.W.2    Pribyl, J.A.3
  • 64
    • 13544262340 scopus 로고    scopus 로고
    • Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro
    • La Motte-Mohs RN, Herer E, Zuniga-Pflucker JC. Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro. Blood. 2005;105:1431-9.
    • (2005) Blood , vol.105 , pp. 1431-1439
    • La Motte-Mohs, R.N.1    Herer, E.2    Zuniga-Pflucker, J.C.3
  • 65
    • 34548140548 scopus 로고    scopus 로고
    • Interleukin-7 contributes to human pro-B-cell development in a mouse stromal cell-dependent culture system
    • 1:CAS:528:DC%2BD2sXpvF2ktb4%3D
    • Taguchi T et al. Interleukin-7 contributes to human pro-B-cell development in a mouse stromal cell-dependent culture system. Exp Hematol. 2007;35:1398-407.
    • (2007) Exp Hematol , vol.35 , pp. 1398-1407
    • Taguchi, T.1
  • 66
    • 42249083035 scopus 로고    scopus 로고
    • Regulation of human B lymphopoiesis by the transforming growth factor-beta superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment
    • 1:CAS:528:DC%2BD1cXlslSisLo%3D
    • Ichii M et al. Regulation of human B lymphopoiesis by the transforming growth factor-beta superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment. Exp Hematol. 2008;36:587-97.
    • (2008) Exp Hematol , vol.36 , pp. 587-597
    • Ichii, M.1
  • 67
    • 84894622392 scopus 로고    scopus 로고
    • Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture
    • 1:CAS:528:DC%2BC2cXhsFGmuw%3D%3D
    • Awong G et al. Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture. Blood. 2013;122:4210-9.
    • (2013) Blood , vol.122 , pp. 4210-4219
    • Awong, G.1
  • 68
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • 1:CAS:528:DC%2BD3sXmvFeltbo%3D
    • Wardemann H et al. Predominant autoantibody production by early human B cell precursors. Science. 2003;301:1374-7.
    • (2003) Science , vol.301 , pp. 1374-1377
    • Wardemann, H.1
  • 69
    • 0030802147 scopus 로고    scopus 로고
    • Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest
    • 1:CAS:528:DyaK2sXls1KlsLo%3D
    • Melamed D, Nemazee D. Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest. Proc Natl Acad Sci U S A. 1997;94:9267-72.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9267-9272
    • Melamed, D.1    Nemazee, D.2
  • 70
    • 0031424315 scopus 로고    scopus 로고
    • Receptor editing in a transgenic mouse model: Site, efficiency, and role in B cell tolerance and antibody diversification
    • 1:CAS:528:DyaK1cXjsFSntw%3D%3D
    • Pelanda R et al. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 1997;7:765-75.
    • (1997) Immunity , vol.7 , pp. 765-775
    • Pelanda, R.1
  • 71
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class i antibody genes
    • 1:CAS:528:DyaL1MXht12ku74%3D A seminal in vivo model to study clonal deletion of autoreactive B cells
    • Nemazee DA, Burki K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature. 1989;337:562-6. A seminal in vivo model to study clonal deletion of autoreactive B cells.
    • (1989) Nature , vol.337 , pp. 562-566
    • Nemazee, D.A.1    Burki, K.2
  • 72
    • 0025887497 scopus 로고
    • B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain
    • 1:CAS:528:DyaK3MXmtlSgsLg%3D
    • Brombacher F, Kohler G, Eibel H. B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain. J Exp Med. 1991;174:1335-46.
    • (1991) J Exp Med , vol.174 , pp. 1335-1346
    • Brombacher, F.1    Kohler, G.2    Eibel, H.3
  • 73
    • 0025980973 scopus 로고
    • Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
    • 1:CAS:528:DyaK3MXpvFygtA%3D%3D
    • Erikson J et al. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature. 1991;349:331-4.
    • (1991) Nature , vol.349 , pp. 331-334
    • Erikson, J.1
  • 74
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • 1:CAS:528:DyaK38XltFKi
    • Hartley SB et al. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature. 1991;353:765-9.
    • (1991) Nature , vol.353 , pp. 765-769
    • Hartley, S.B.1
  • 75
    • 84865721122 scopus 로고    scopus 로고
    • Endogenous antigen tunes the responsiveness of naive B cells but not T cells
    • 1:CAS:528:DC%2BC38Xht1WktrnP A very elegant expermental model demonstrating that all peripheral B cells bind autoantigens although with different avidities
    • Zikherman J, Parameswaran R, Weiss A. Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Nature. 2012;489:160-4. A very elegant expermental model demonstrating that all peripheral B cells bind autoantigens although with different avidities.
    • (2012) Nature , vol.489 , pp. 160-164
    • Zikherman, J.1    Parameswaran, R.2    Weiss, A.3
  • 76
    • 0037375554 scopus 로고    scopus 로고
    • Antigen receptor selection by editing or downregulation of V(D)J recombination
    • 1:CAS:528:DC%2BD3sXhvFaiu7Y%3D
    • Nemazee D, Hogquist KA. Antigen receptor selection by editing or downregulation of V(D)J recombination. Curr Opin Immunol. 2003;15:182-9.
    • (2003) Curr Opin Immunol , vol.15 , pp. 182-189
    • Nemazee, D.1    Hogquist, K.A.2
  • 77
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • 1:CAS:528:DyaK3sXhsVKjtrc%3D
    • Hartley SB et al. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell. 1993;72:325-35.
    • (1993) Cell , vol.72 , pp. 325-335
    • Hartley, S.B.1
  • 78
    • 0242407710 scopus 로고    scopus 로고
    • The regulation of lupus-associated autoantibodies: Immunoglobulin transgenic models
    • 1:CAS:528:DC%2BD3sXptVeqsbk%3D
    • Fields ML, Erikson J. The regulation of lupus-associated autoantibodies: immunoglobulin transgenic models. Curr Opin Immunol. 2003;15:709-17.
    • (2003) Curr Opin Immunol , vol.15 , pp. 709-717
    • Fields, M.L.1    Erikson, J.2
  • 79
  • 80
    • 84875461762 scopus 로고    scopus 로고
    • Mechanisms of disease for the clinician: Systemic lupus erythematosus
    • Frieri M. Mechanisms of disease for the clinician: systemic lupus erythematosus. Ann Allergy Asthma Immunol. 2013;110:228-32.
    • (2013) Ann Allergy Asthma Immunol , vol.110 , pp. 228-232
    • Frieri, M.1
  • 81
    • 0036794398 scopus 로고    scopus 로고
    • BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
    • 1:CAS:528:DC%2BD38XnsVGrsLo%3D
    • Claudio E, Brown K, Park S, Wang H, Siebenlist U. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol. 2002;3:958-65.
    • (2002) Nat Immunol , vol.3 , pp. 958-965
    • Claudio, E.1    Brown, K.2    Park, S.3    Wang, H.4    Siebenlist, U.5
  • 82
    • 84889686883 scopus 로고    scopus 로고
    • NF-kappaB and systemic lupus erythematosus: Examining the link
    • Zubair A, Frieri M. NF-kappaB and systemic lupus erythematosus: examining the link. J Nephrol. 2013;26:953-9.
    • (2013) J Nephrol , vol.26 , pp. 953-959
    • Zubair, A.1    Frieri, M.2
  • 83
    • 33750524262 scopus 로고    scopus 로고
    • BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism
    • 1:CAS:528:DC%2BD28XhtFGqtL%2FN
    • Patke A, Mecklenbrauker I, Erdjument-Bromage H, Tempst P, Tarakhovsky A. BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism. J Exp Med. 2006;203:2551-62.
    • (2006) J Exp Med , vol.203 , pp. 2551-2562
    • Patke, A.1    Mecklenbrauker, I.2    Erdjument-Bromage, H.3    Tempst, P.4    Tarakhovsky, A.5
  • 84
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • 1:CAS:528:DC%2BD3MXntVCitrg%3D
    • Thompson JS et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science. 2001;293:2108-11.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1
  • 85
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology
    • 1:CAS:528:DC%2BD2cXmt1Omu7o%3D
    • Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol. 2004;173:2245-52.
    • (2004) J Immunol , vol.173 , pp. 2245-2252
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3    Rajewsky, K.4    Schmidt-Supprian, M.5
  • 86
    • 69549128384 scopus 로고    scopus 로고
    • B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans
    • 1:CAS:528:DC%2BD1MXhtFWksLfN
    • Warnatz K et al. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc Natl Acad Sci U S A. 2009;106:13945-50.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 13945-13950
    • Warnatz, K.1
  • 87
    • 84897469677 scopus 로고    scopus 로고
    • A common SNP impairs B cell activating factor receptor's multimerization, contributing to common variable immunodeficiency
    • doi: 10.1016/j.jaci.2013.11.021
    • Pieper K, et al. A common SNP impairs B cell activating factor receptor's multimerization, contributing to common variable immunodeficiency. J Allergy Clin Immunol. 2014. doi: 10.1016/j.jaci.2013.11.021.
    • (2014) J Allergy Clin Immunol.
    • Pieper, K.1
  • 88
    • 84876918036 scopus 로고    scopus 로고
    • Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency
    • 1:CAS:528:DC%2BC3sXlt1CntL8%3D e1373
    • Greil J et al. Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency. J Allergy Clin Immunol. 2013;131:1376-83. e1373.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1376-1383
    • Greil, J.1
  • 89
    • 84873348862 scopus 로고    scopus 로고
    • Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects
    • 1:CAS:528:DC%2BC3sXhvFWlu7s%3D The paper underlines the strict dependece of human B cell development on NF-kappaB signaling
    • Stepensky P et al. Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects. J Allergy Clin Immunol. 2013;131:477-85. The paper underlines the strict dependece of human B cell development on NF-kappaB signaling.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 477-485
    • Stepensky, P.1
  • 91
    • 52949088297 scopus 로고    scopus 로고
    • Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
    • 1:CAS:528:DC%2BD1cXhtFKhtbbP
    • Yu X et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 2008;455:532-6.
    • (2008) Nature , vol.455 , pp. 532-536
    • Yu, X.1
  • 92
    • 84859717525 scopus 로고    scopus 로고
    • Germinal center selection and the development of memory B and plasma cells
    • Shlomchik MJ, Weisel F. Germinal center selection and the development of memory B and plasma cells. Immunol Rev. 2012;247:52-63.
    • (2012) Immunol Rev , vol.247 , pp. 52-63
    • Shlomchik, M.J.1    Weisel, F.2
  • 94
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • 1:CAS:528:DyaK2sXmtlOmsrk%3D
    • Lam KP, Kuhn R, Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell. 1997;90:1073-83.
    • (1997) Cell , vol.90 , pp. 1073-1083
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 95
    • 0024799016 scopus 로고
    • Mechanism of antigen-driven selection in germinal centres
    • 1:STN:280:DyaK3c%2FotFyktg%3D%3D
    • Liu YJ et al. Mechanism of antigen-driven selection in germinal centres. Nature. 1989;342:929-31.
    • (1989) Nature , vol.342 , pp. 929-931
    • Liu, Y.J.1
  • 96
    • 0025951891 scopus 로고
    • Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
    • 1:CAS:528:DyaK38XotFKlsA%3D%3D
    • Liu YJ, Zhang J, Lane PJ, Chan EY, MacLennan IC. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur J Immunol. 1991;21:2951-62.
    • (1991) Eur J Immunol , vol.21 , pp. 2951-2962
    • Liu, Y.J.1    Zhang, J.2    Lane, P.J.3    Chan, E.Y.4    Maclennan, I.C.5
  • 97
    • 33846635838 scopus 로고    scopus 로고
    • Imaging of germinal center selection events during affinity maturation
    • 1:CAS:528:DC%2BD2sXotFCitQ%3D%3D
    • Allen CD, Okada T, Tang HL, Cyster JG. Imaging of germinal center selection events during affinity maturation. Science. 2007;315:528-31.
    • (2007) Science , vol.315 , pp. 528-531
    • Allen, C.D.1    Okada, T.2    Tang, H.L.3    Cyster, J.G.4
  • 98
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • 1:CAS:528:DC%2BD3cXmsFWit7g%3D
    • Muramatsu M et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 2000;102:553-63.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1
  • 99
    • 0034264851 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
    • 1:CAS:528:DC%2BD3cXmsFWit7k%3D
    • Revy P et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell. 2000;102:565-75.
    • (2000) Cell , vol.102 , pp. 565-575
    • Revy, P.1
  • 100
    • 67649221652 scopus 로고    scopus 로고
    • Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
    • 1:CAS:528:DC%2BD1MXntVWisrg%3D
    • Phan TG, Green JA, Gray EE, Xu Y, Cyster JG. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol. 2009;10:786-93.
    • (2009) Nat Immunol , vol.10 , pp. 786-793
    • Phan, T.G.1    Green, J.A.2    Gray, E.E.3    Xu, Y.4    Cyster, J.G.5
  • 101
    • 21844450539 scopus 로고    scopus 로고
    • Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
    • Okada T et al. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol. 2005;3:e150.
    • (2005) PLoS Biol , vol.3 , pp. 150
    • Okada, T.1
  • 102
    • 69349087555 scopus 로고    scopus 로고
    • EBI2 mediates B cell segregation between the outer and centre follicle
    • 1:CAS:528:DC%2BD1MXosFWhsr4%3D
    • Pereira JP, Kelly LM, Xu Y, Cyster JG. EBI2 mediates B cell segregation between the outer and centre follicle. Nature. 2009;460:1122-6.
    • (2009) Nature , vol.460 , pp. 1122-1126
    • Pereira, J.P.1    Kelly, L.M.2    Xu, Y.3    Cyster, J.G.4
  • 103
    • 79960909447 scopus 로고    scopus 로고
    • Oxysterols direct immune cell migration via EBI2
    • 1:CAS:528:DC%2BC3MXpsFais7o%3D
    • Hannedouche S et al. Oxysterols direct immune cell migration via EBI2. Nature. 2011;475:524-7.
    • (2011) Nature , vol.475 , pp. 524-527
    • Hannedouche, S.1
  • 104
    • 84866518376 scopus 로고    scopus 로고
    • Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses
    • 1:CAS:528:DC%2BC38XhtlymurzM
    • Yi T et al. Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses. Immunity. 2012;37:535-48.
    • (2012) Immunity , vol.37 , pp. 535-548
    • Yi, T.1
  • 105
    • 80053055261 scopus 로고    scopus 로고
    • EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues
    • 1:CAS:528:DC%2BC3MXhtFeksbrL
    • Kelly LM, Pereira JP, Yi T, Xu Y, Cyster JG. EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues. J Immunol. 2011;187:3026-32.
    • (2011) J Immunol , vol.187 , pp. 3026-3032
    • Kelly, L.M.1    Pereira, J.P.2    Yi, T.3    Xu, Y.4    Cyster, J.G.5
  • 106
    • 84890233027 scopus 로고    scopus 로고
    • Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection
    • 1:CAS:528:DC%2BC3sXhslWis7zJ The paper shows how shuttling between dark and light zone regulates GC B cell proliferation, affinity maturation and memory vs. plasma cell development
    • Bannard O et al. Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection. Immunity. 2013;39:912-24. The paper shows how shuttling between dark and light zone regulates GC B cell proliferation, affinity maturation and memory vs. plasma cell development.
    • (2013) Immunity , vol.39 , pp. 912-924
    • Bannard, O.1
  • 107
    • 84862908273 scopus 로고    scopus 로고
    • Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers
    • 1:CAS:528:DC%2BC3MXhsFOhsbfK
    • Wang X et al. Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers. J Exp Med. 2011;208:2497-510.
    • (2011) J Exp Med , vol.208 , pp. 2497-2510
    • Wang, X.1
  • 108
    • 79957610938 scopus 로고    scopus 로고
    • The outs and the ins of sphingosine-1-phosphate in immunity
    • 1:CAS:528:DC%2BC3MXls1Kgurk%3D
    • Spiegel S, Milstien S. The outs and the ins of sphingosine-1-phosphate in immunity. Nat Rev Immunol. 2011;11:403-15.
    • (2011) Nat Rev Immunol , vol.11 , pp. 403-415
    • Spiegel, S.1    Milstien, S.2
  • 110
    • 0034670042 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells
    • 1:CAS:528:DC%2BD3cXotFKkur0%3D
    • Yatomi Y et al. Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells. Blood. 2000;96:3431-8.
    • (2000) Blood , vol.96 , pp. 3431-3438
    • Yatomi, Y.1
  • 111
    • 51749096383 scopus 로고    scopus 로고
    • The vascular S1P gradient-cellular sources and biological significance
    • 1:CAS:528:DC%2BD1cXhtVKjtbrF
    • Hla T, Venkataraman K, Michaud J. The vascular S1P gradient-cellular sources and biological significance. Biochim Biophys Acta. 2008;1781:477-82.
    • (2008) Biochim Biophys Acta , vol.1781 , pp. 477-482
    • Hla, T.1    Venkataraman, K.2    Michaud, J.3
  • 112
    • 41449112571 scopus 로고    scopus 로고
    • Vascular endothelium as a contributor of plasma sphingosine 1-phosphate
    • 1:CAS:528:DC%2BD1cXjs1Wmtr0%3D
    • Venkataraman K et al. Vascular endothelium as a contributor of plasma sphingosine 1-phosphate. Circ Res. 2008;102:669-76.
    • (2008) Circ Res , vol.102 , pp. 669-676
    • Venkataraman, K.1
  • 113
    • 34247379074 scopus 로고    scopus 로고
    • Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
    • 1:CAS:528:DC%2BD2sXktVeku70%3D
    • Pappu R et al. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science. 2007;316:295-8.
    • (2007) Science , vol.316 , pp. 295-298
    • Pappu, R.1
  • 114
    • 24644469502 scopus 로고    scopus 로고
    • Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
    • 1:CAS:528:DC%2BD2MXpvFCis7g%3D
    • Schwab SR et al. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005;309:1735-9.
    • (2005) Science , vol.309 , pp. 1735-1739
    • Schwab, S.R.1
  • 115
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • 1:CAS:528:DC%2BD2cXltFCguw%3D%3D
    • Matloubian M et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004;427:355-60.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1
  • 116
    • 84905562170 scopus 로고    scopus 로고
    • S1P-receptors control B cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia and multiple sclerosis
    • 2014 in press. The first comprehenisve analysis of S1P-receptor expression and signaling in human B cells
    • Sic H., et al. S1P-receptors control B cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia and multiple sclerosis. J Allergy Clin Immunol. 2014 in press. The first comprehenisve analysis of S1P-receptor expression and signaling in human B cells.
    • J Allergy Clin Immunol
    • Sic, H.1
  • 117
    • 84859729872 scopus 로고    scopus 로고
    • S1PR2 links germinal center confinement and growth regulation
    • Green JA, Cyster JG. S1PR2 links germinal center confinement and growth regulation. Immunol Rev. 2012;247:36-51.
    • (2012) Immunol Rev , vol.247 , pp. 36-51
    • Green, J.A.1    Cyster, J.G.2
  • 118
    • 0028324816 scopus 로고
    • Germinal centers
    • 1:CAS:528:DyaK2cXivFKjurk%3D
    • MacLennan IC. Germinal centers. Annu Rev Immunol. 1994;12:117-39.
    • (1994) Annu Rev Immunol , vol.12 , pp. 117-139
    • Maclennan, I.C.1
  • 119
    • 0029870531 scopus 로고    scopus 로고
    • Centrocytes rapidly adopt a memory B cell phenotype on co-culture with autologous germinal centre T cell-enriched preparations
    • 1:CAS:528:DyaK28Xjt1Kmtbk%3D
    • Casamayor-Palleja M, Feuillard J, Ball J, Drew M, MacLennan IC. Centrocytes rapidly adopt a memory B cell phenotype on co-culture with autologous germinal centre T cell-enriched preparations. Int Immunol. 1996;8:737-44.
    • (1996) Int Immunol , vol.8 , pp. 737-744
    • Casamayor-Palleja, M.1    Feuillard, J.2    Ball, J.3    Drew, M.4    Maclennan, I.C.5
  • 120
    • 0035942781 scopus 로고    scopus 로고
    • B cells acquire antigen from target cells after synapse formation
    • 1:CAS:528:DC%2BD3MXkt1ejt7k%3D
    • Batista FD, Iber D, Neuberger MS. B cells acquire antigen from target cells after synapse formation. Nature. 2001;411:489-94.
    • (2001) Nature , vol.411 , pp. 489-494
    • Batista, F.D.1    Iber, D.2    Neuberger, M.S.3
  • 121
    • 79958255209 scopus 로고    scopus 로고
    • A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center
    • 1:CAS:528:DC%2BC3MXns1Skurs%3D
    • Schwickert TA et al. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med. 2011;208:1243-52.
    • (2011) J Exp Med , vol.208 , pp. 1243-1252
    • Schwickert, T.A.1
  • 122
    • 13844296663 scopus 로고    scopus 로고
    • Immunological synapses are versatile structures enabling selective T cell polarization
    • 1:CAS:528:DC%2BD2MXisFSqs7w%3D
    • Depoil D et al. Immunological synapses are versatile structures enabling selective T cell polarization. Immunity. 2005;22:185-94.
    • (2005) Immunity , vol.22 , pp. 185-194
    • Depoil, D.1
  • 123
    • 0035099037 scopus 로고    scopus 로고
    • Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
    • 1:CAS:528:DC%2BD3MXivFOqurk%3D
    • Takahashi Y, Ohta H, Takemori T. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. Immunity. 2001;14:181-92.
    • (2001) Immunity , vol.14 , pp. 181-192
    • Takahashi, Y.1    Ohta, H.2    Takemori, T.3
  • 124
    • 0032882703 scopus 로고    scopus 로고
    • Fas ligand expression in the germinal centre
    • 1:CAS:528:DyaK1MXms12mtL0%3D
    • Verbeke CS, Wenthe U, Zentgraf H. Fas ligand expression in the germinal centre. J Pathol. 1999;189:155-60.
    • (1999) J Pathol , vol.189 , pp. 155-160
    • Verbeke, C.S.1    Wenthe, U.2    Zentgraf, H.3
  • 125
    • 33750502877 scopus 로고    scopus 로고
    • High affinity germinal center B cells are actively selected into the plasma cell compartment
    • 1:CAS:528:DC%2BD28XhtFGqt7fE
    • Phan TG et al. High affinity germinal center B cells are actively selected into the plasma cell compartment. J Exp Med. 2006;203:2419-24.
    • (2006) J Exp Med , vol.203 , pp. 2419-2424
    • Phan, T.G.1
  • 126
    • 84857802310 scopus 로고    scopus 로고
    • Genetic CD21 deficiency is associated with hypogammaglobulinemia
    • 1:CAS:528:DC%2BC38XjsVSqsbo%3D e806
    • Thiel J et al. Genetic CD21 deficiency is associated with hypogammaglobulinemia. J Allergy Clin Immunol. 2012;129:801-10. e806.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 801-810
    • Thiel, J.1
  • 127
    • 33646347921 scopus 로고    scopus 로고
    • An antibody-deficiency syndrome due to mutations in the CD19 gene
    • van Zelm MC et al. An antibody-deficiency syndrome due to mutations in the CD19 gene. N Engl J Med. 2006;354:1901-12.
    • (2006) N Engl J Med , vol.354 , pp. 1901-1912
    • Van Zelm, M.C.1
  • 128
    • 77951146803 scopus 로고    scopus 로고
    • CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency
    • van Zelm MC et al. CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J Clin Invest. 2010;120:1265-74.
    • (2010) J Clin Invest , vol.120 , pp. 1265-1274
    • Van Zelm, M.C.1
  • 129
    • 0037438633 scopus 로고    scopus 로고
    • Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses
    • 1:CAS:528:DC%2BD3sXktlGgsg%3D%3D
    • Tangye SG, Avery DT, Deenick EK, Hodgkin PD. Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses. J Immunol. 2003;170:686-94.
    • (2003) J Immunol , vol.170 , pp. 686-694
    • Tangye, S.G.1    Avery, D.T.2    Deenick, E.K.3    Hodgkin, P.D.4
  • 130
    • 0000418386 scopus 로고    scopus 로고
    • The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow
    • 1:CAS:528:DyaK1cXltlaltb8%3D
    • Wang LC et al. The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow. Genes Dev. 1998;12:2392-402.
    • (1998) Genes Dev , vol.12 , pp. 2392-2402
    • Wang, L.C.1
  • 131
    • 20044366916 scopus 로고    scopus 로고
    • Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding
    • 1:CAS:528:DC%2BD2MXhsV2qu7Y%3D
    • Hymowitz SG et al. Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J Biol Chem. 2005;280:7218-27.
    • (2005) J Biol Chem , vol.280 , pp. 7218-7227
    • Hymowitz, S.G.1
  • 132
    • 12244251445 scopus 로고    scopus 로고
    • Stat3 dimerization regulated by reversible acetylation of a single lysine residue
    • 1:CAS:528:DC%2BD2MXisVKktA%3D%3D
    • Yuan ZL, Guan YJ, Chatterjee D, Chin YE. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science. 2005;307:269-73.
    • (2005) Science , vol.307 , pp. 269-273
    • Yuan, Z.L.1    Guan, Y.J.2    Chatterjee, D.3    Chin, Y.E.4
  • 133
    • 84878574917 scopus 로고    scopus 로고
    • Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid
    • 1:CAS:528:DC%2BC3sXjsFymsbk%3D
    • Kienzler AK, Rizzi M, Reith M, Nutt SL, Eibel H. Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid. J Allergy Clin Immunol. 2013;131:1695-9.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1695-1699
    • Kienzler, A.K.1    Rizzi, M.2    Reith, M.3    Nutt, S.L.4    Eibel, H.5
  • 134
    • 77649115437 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression
    • 1:CAS:528:DC%2BC3cXjtFaiur4%3D
    • Yamaguchi T et al. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 2010;24:455-69.
    • (2010) Genes Dev , vol.24 , pp. 455-469
    • Yamaguchi, T.1
  • 135
    • 20644461729 scopus 로고    scopus 로고
    • Transcriptional networks in developing and mature B cells
    • 1:CAS:528:DC%2BD2MXks1GmsLk%3D
    • Matthias P, Rolink AG. Transcriptional networks in developing and mature B cells. Nat Rev Immunol. 2005;5:497-508.
    • (2005) Nat Rev Immunol , vol.5 , pp. 497-508
    • Matthias, P.1    Rolink, A.G.2
  • 136
    • 0033166301 scopus 로고    scopus 로고
    • Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A
    • O'Riordan M, Grosschedl R. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity. 1999;11:21-31.
    • (1999) Immunity , vol.11 , pp. 21-31
    • O'Riordan, M.1    Grosschedl, R.2
  • 137
    • 0034959755 scopus 로고    scopus 로고
    • Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis
    • 1:CAS:528:DC%2BD3MXkvFSlt7o%3D
    • Horcher M, Souabni A, Busslinger M. Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. Immunity. 2001;14:779-90.
    • (2001) Immunity , vol.14 , pp. 779-790
    • Horcher, M.1    Souabni, A.2    Busslinger, M.3
  • 138
    • 0030950523 scopus 로고    scopus 로고
    • Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
    • 1:CAS:528:DyaK2sXivVGgsbo%3D
    • Lin Y, Wong K, Calame K. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science. 1997;276:596-9.
    • (1997) Science , vol.276 , pp. 596-599
    • Lin, Y.1    Wong, K.2    Calame, K.3
  • 139
    • 0034669911 scopus 로고    scopus 로고
    • Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo
    • 1:CAS:528:DC%2BD3cXot1Grsr8%3D
    • Angelin-Duclos C, Cattoretti G, Lin KI, Calame K. Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol. 2000;165:5462-71.
    • (2000) J Immunol , vol.165 , pp. 5462-5471
    • Angelin-Duclos, C.1    Cattoretti, G.2    Lin, K.I.3    Calame, K.4
  • 140
    • 0036272784 scopus 로고    scopus 로고
    • Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells
    • 1:CAS:528:DC%2BD38Xks1yrtrs%3D
    • Lin KI, Angelin-Duclos C, Kuo TC, Calame K. Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol Cell Biol. 2002;22:4771-80.
    • (2002) Mol Cell Biol , vol.22 , pp. 4771-4780
    • Lin, K.I.1    Angelin-Duclos, C.2    Kuo, T.C.3    Calame, K.4
  • 141
    • 18444395232 scopus 로고    scopus 로고
    • Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
    • 1:CAS:528:DC%2BD38XmtVelurk%3D
    • Shaffer AL et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity. 2002;17:51-62.
    • (2002) Immunity , vol.17 , pp. 51-62
    • Shaffer, A.L.1
  • 142
    • 0142219442 scopus 로고    scopus 로고
    • Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells
    • 1:CAS:528:DC%2BD3sXosF2rs70%3D
    • Shapiro-Shelef M et al. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity. 2003;19:607-20.
    • (2003) Immunity , vol.19 , pp. 607-620
    • Shapiro-Shelef, M.1
  • 143
    • 7244231012 scopus 로고    scopus 로고
    • Plasma cell ontogeny defined by quantitative changes in blimp-1 expression
    • 1:CAS:528:DC%2BD2cXovVensLo%3D
    • Kallies A et al. Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med. 2004;200:967-77.
    • (2004) J Exp Med , vol.200 , pp. 967-977
    • Kallies, A.1
  • 144
    • 3142658576 scopus 로고    scopus 로고
    • XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
    • 1:CAS:528:DC%2BD2cXmtlKjt74%3D
    • Shaffer AL et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 2004;21:81-93.
    • (2004) Immunity , vol.21 , pp. 81-93
    • Shaffer, A.L.1
  • 145
    • 33745182931 scopus 로고    scopus 로고
    • Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
    • 1:CAS:528:DC%2BD28XlvFGjsbs%3D
    • Klein U et al. Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol. 2006;7:773-82.
    • (2006) Nat Immunol , vol.7 , pp. 773-782
    • Klein, U.1
  • 146
    • 34248543774 scopus 로고    scopus 로고
    • Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1
    • 1:CAS:528:DC%2BD2sXmt1ajs7s%3D
    • Kallies A et al. Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity. 2007;26:555-66.
    • (2007) Immunity , vol.26 , pp. 555-566
    • Kallies, A.1
  • 147
    • 0029045421 scopus 로고
    • BCL-6 protein is expressed in germinal-center B cells
    • 1:CAS:528:DyaK2MXmsVOktb4%3D
    • Cattoretti G et al. BCL-6 protein is expressed in germinal-center B cells. Blood. 1995;86:45-53.
    • (1995) Blood , vol.86 , pp. 45-53
    • Cattoretti, G.1
  • 148
    • 0029904294 scopus 로고    scopus 로고
    • BCL-6 expression during B-cell activation
    • 1:CAS:528:DyaK28XjsFGitL8%3D
    • Allman D et al. BCL-6 expression during B-cell activation. Blood. 1996;87:5257-68.
    • (1996) Blood , vol.87 , pp. 5257-5268
    • Allman, D.1
  • 149
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • 1:CAS:528:DyaK2sXivVGgsL4%3D
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science. 1997;276:589-92.
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 150
    • 77649222742 scopus 로고    scopus 로고
    • Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells
    • 1:CAS:528:DC%2BC3cXhvFOitrY%3D
    • Basso K et al. Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. Blood. 2010;115:975-84.
    • (2010) Blood , vol.115 , pp. 975-984
    • Basso, K.1
  • 151
    • 3142728530 scopus 로고    scopus 로고
    • Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation
    • 1:CAS:528:DC%2BD2cXlsVGisLk%3D
    • Tunyaplin C et al. Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation. J Immunol. 2004;173:1158-65.
    • (2004) J Immunol , vol.173 , pp. 1158-1165
    • Tunyaplin, C.1
  • 152
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • 1:CAS:528:DC%2BD3cXmsVKnu78%3D
    • Shaffer AL et al. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 2000;13:199-212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1
  • 153
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • The report of the 1,000 genome project
    • Abecasis GR et al. An integrated map of genetic variation from 1,092 human genomes. Nature. 2012;491:56-65. The report of the 1,000 genome project.
    • (2012) Nature , vol.491 , pp. 56-65
    • Abecasis, G.R.1
  • 154
    • 67650506692 scopus 로고    scopus 로고
    • BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma
    • 1:CAS:528:DC%2BD1MXptVWlt7Y%3D
    • Saito M et al. BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. Proc Natl Acad Sci U S A. 2009;106:11294-9.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11294-11299
    • Saito, M.1
  • 155
    • 28544444025 scopus 로고    scopus 로고
    • Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
    • 1:CAS:528:DC%2BD2MXhtlSqtLnJ
    • Shapiro-Shelef M, Lin KI, Savitsky D, Liao J, Calame K. Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow. J Exp Med. 2005;202:1471-6.
    • (2005) J Exp Med , vol.202 , pp. 1471-1476
    • Shapiro-Shelef, M.1    Lin, K.I.2    Savitsky, D.3    Liao, J.4    Calame, K.5
  • 156
    • 0030052190 scopus 로고    scopus 로고
    • Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1
    • 1:CAS:528:DyaK28Xht1Sntr8%3D
    • Reimold AM et al. Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1. J Exp Med. 1996;183:393-401.
    • (1996) J Exp Med , vol.183 , pp. 393-401
    • Reimold, A.M.1
  • 157
    • 0037385313 scopus 로고    scopus 로고
    • Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
    • 1:CAS:528:DC%2BD3sXitlyqs70%3D
    • Iwakoshi NN et al. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol. 2003;4:321-9.
    • (2003) Nat Immunol , vol.4 , pp. 321-329
    • Iwakoshi, N.N.1
  • 158
    • 70350452319 scopus 로고    scopus 로고
    • XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
    • 1:CAS:528:DC%2BD1MXht1SrtbjJ
    • Todd DJ et al. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med. 2009;206:2151-9.
    • (2009) J Exp Med , vol.206 , pp. 2151-2159
    • Todd, D.J.1
  • 159
    • 15444346834 scopus 로고    scopus 로고
    • Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
    • 1:CAS:528:DyaK2sXnvVCltg%3D%3D
    • Mittrucker HW et al. Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science. 1997;275:540-3.
    • (1997) Science , vol.275 , pp. 540-543
    • Mittrucker, H.W.1
  • 160
    • 33747133955 scopus 로고    scopus 로고
    • Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
    • 1:CAS:528:DC%2BD28XpvVGjsr4%3D
    • Sciammas R et al. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity. 2006;25:225-36.
    • (2006) Immunity , vol.25 , pp. 225-236
    • Sciammas, R.1
  • 161
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B
    • 1:CAS:528:DyaK2MXit1eqsrs%3D
    • Berberich I, Shu GL, Clark EA. Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B. J Immunol. 1994;153:4357-66.
    • (1994) J Immunol , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 162
    • 0029052398 scopus 로고
    • Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers
    • 1:CAS:528:DyaK2MXmvVagsr0%3D
    • Han S et al. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J Immunol. 1995;155:556-67.
    • (1995) J Immunol , vol.155 , pp. 556-567
    • Han, S.1
  • 163
    • 10244261528 scopus 로고    scopus 로고
    • Tracking CD40 signaling during germinal center development
    • 1:CAS:528:DC%2BD2cXhtFaju7bM
    • Basso K et al. Tracking CD40 signaling during germinal center development. Blood. 2004;104:4088-96.
    • (2004) Blood , vol.104 , pp. 4088-4096
    • Basso, K.1
  • 164
    • 34548237299 scopus 로고    scopus 로고
    • A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
    • 1:CAS:528:DC%2BD2sXhtVKqsbrO
    • Saito M et al. A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer cell. 2007;12:280-92.
    • (2007) Cancer Cell , vol.12 , pp. 280-292
    • Saito, M.1
  • 165
    • 0035940417 scopus 로고    scopus 로고
    • Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM
    • 1:CAS:528:DC%2BD3MXotFaiurY%3D
    • Ferrari S et al. Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM. Proc Natl Acad Sci U S A. 2001;98:12614-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12614-12619
    • Ferrari, S.1
  • 166
    • 0035286726 scopus 로고    scopus 로고
    • Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia
    • 1:CAS:528:DC%2BD3MXhvVWisLg%3D
    • Jain A et al. Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia. Nat Immunol. 2001;2:223-8.
    • (2001) Nat Immunol , vol.2 , pp. 223-228
    • Jain, A.1
  • 167
    • 33749531054 scopus 로고    scopus 로고
    • Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21
    • 1:CAS:528:DC%2BD28XhtVansrjL
    • Good KL, Bryant VL, Tangye SG. Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J Immunol. 2006;177:5236-47.
    • (2006) J Immunol , vol.177 , pp. 5236-5247
    • Good, K.L.1    Bryant, V.L.2    Tangye, S.G.3
  • 168
    • 84873536866 scopus 로고    scopus 로고
    • IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells
    • 1:CAS:528:DC%2BC3sXhvFGmtr4%3D
    • Ding BB, Bi E, Chen H, Yu JJ, Ye BH. IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells. J Immunol. 2013;190:1827-36.
    • (2013) J Immunol , vol.190 , pp. 1827-1836
    • Ding, B.B.1    Bi, E.2    Chen, H.3    Yu, J.J.4    Ye, B.H.5
  • 169
    • 6344269331 scopus 로고    scopus 로고
    • Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
    • 1:CAS:528:DC%2BD2cXos1Gitbc%3D
    • Ozaki K et al. Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J Immunol. 2004;173:5361-71.
    • (2004) J Immunol , vol.173 , pp. 5361-5371
    • Ozaki, K.1
  • 170
    • 11144355735 scopus 로고    scopus 로고
    • Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells
    • 1:CAS:528:DC%2BD2cXjt1Cks7g%3D
    • Pene J et al. Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells. J Immunol. 2004;172:5154-7.
    • (2004) J Immunol , vol.172 , pp. 5154-5157
    • Pene, J.1
  • 171
    • 84877614089 scopus 로고    scopus 로고
    • Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
    • 1:CAS:528:DC%2BC3sXjvFOns7g%3D The paper shows the role of IL-21R signaling in immune responses of B, T and NK cells
    • Kotlarz D et al. Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome. J Exp Med. 2013;210:433-43. The paper shows the role of IL-21R signaling in immune responses of B, T and NK cells.
    • (2013) J Exp Med , vol.210 , pp. 433-443
    • Kotlarz, D.1
  • 172
    • 20144369616 scopus 로고    scopus 로고
    • STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
    • 1:CAS:528:DC%2BD2MXhtleqt7c%3D
    • Scheeren FA et al. STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression. Nat Immunol. 2005;6:303-13.
    • (2005) Nat Immunol , vol.6 , pp. 303-313
    • Scheeren, F.A.1
  • 173
    • 44449145063 scopus 로고    scopus 로고
    • STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation
    • 1:CAS:528:DC%2BD1cXjsVKqtrY%3D
    • Diehl SA et al. STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation. J Immunol. 2008;180:4805-15.
    • (2008) J Immunol , vol.180 , pp. 4805-4815
    • Diehl, S.A.1
  • 174
    • 76149139419 scopus 로고    scopus 로고
    • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
    • 1:CAS:528:DC%2BC3cXht1ekt78%3D
    • Avery DT et al. B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med. 2010;207:155-71.
    • (2010) J Exp Med , vol.207 , pp. 155-171
    • Avery, D.T.1
  • 175
    • 35348960378 scopus 로고    scopus 로고
    • STAT3 mutations in the hyper-IgE syndrome
    • 1:CAS:528:DC%2BD2sXht1SgurzL
    • Holland SM et al. STAT3 mutations in the hyper-IgE syndrome. N Engl J Med. 2007;357:1608-19.
    • (2007) N Engl J Med , vol.357 , pp. 1608-1619
    • Holland, S.M.1
  • 176
    • 34548317417 scopus 로고    scopus 로고
    • Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
    • 1:CAS:528:DC%2BD2sXps12nsLc%3D
    • Minegishi Y et al. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007;448:1058-62.
    • (2007) Nature , vol.448 , pp. 1058-1062
    • Minegishi, Y.1
  • 177
    • 84878539074 scopus 로고    scopus 로고
    • Intermediate phenotypes in patients with autosomal dominant hyper-IgE syndrome caused by somatic mosaicism
    • 1:CAS:528:DC%2BC3sXmvVWiu74%3D
    • Hsu AP et al. Intermediate phenotypes in patients with autosomal dominant hyper-IgE syndrome caused by somatic mosaicism. J Allergy Clin Immunol. 2013;131:1586-93.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1586-1593
    • Hsu, A.P.1


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