-
1
-
-
0021246815
-
Functional anatomy of germinal centers
-
Nieuwenhuis P, Opstelten D. Functional anatomy of germinal centers. Am J Anat 1984;170:421-435.
-
(1984)
Am J Anat
, vol.170
, pp. 421-435
-
-
Nieuwenhuis, P.1
Opstelten, D.2
-
3
-
-
34548036949
-
Germinal-center organization and cellular dynamics
-
Allen CD, Okada T, Cyster JG. Germinal-center organization and cellular dynamics. Immunity 2007;27:190-202.
-
(2007)
Immunity
, vol.27
, pp. 190-202
-
-
Allen, C.D.1
Okada, T.2
Cyster, J.G.3
-
4
-
-
0011084483
-
Variations in affinities of antibodies during the immune response
-
Eisen HN, Siskind GW. Variations in affinities of antibodies during the immune response. Biochemistry 1964;3:996-1008.
-
(1964)
Biochemistry
, vol.3
, pp. 996-1008
-
-
Eisen, H.N.1
Siskind, G.W.2
-
5
-
-
0026331458
-
Maturation of the immune response in germinal centers
-
Berek C, Berger A, Apel M. Maturation of the immune response in germinal centers. Cell 1991;67:1121-1129.
-
(1991)
Cell
, vol.67
, pp. 1121-1129
-
-
Berek, C.1
Berger, A.2
Apel, M.3
-
6
-
-
0026060620
-
Intraclonal generation of antibody mutants in germinal centres
-
Jacob J, Kelsoe G, Rajewsky K, Weiss U. Intraclonal generation of antibody mutants in germinal centres. Nature 1991;354:389-392.
-
(1991)
Nature
, vol.354
, pp. 389-392
-
-
Jacob, J.1
Kelsoe, G.2
Rajewsky, K.3
Weiss, U.4
-
7
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011;29:621-663.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
8
-
-
0028153996
-
B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells
-
Lane P, et al. B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells. J Exp Med 1994;179:819-830.
-
(1994)
J Exp Med
, vol.179
, pp. 819-830
-
-
Lane, P.1
-
9
-
-
0032127301
-
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
-
Futterer A, Mink K, Luz A, Kosco-Vilbois MH, Pfeffer K. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 1998;9:59-70.
-
(1998)
Immunity
, vol.9
, pp. 59-70
-
-
Futterer, A.1
Mink, K.2
Luz, A.3
Kosco-Vilbois, M.H.4
Pfeffer, K.5
-
10
-
-
0006379753
-
Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice
-
Matsumoto M, et al. Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice. Nature 1996;382:462-466.
-
(1996)
Nature
, vol.382
, pp. 462-466
-
-
Matsumoto, M.1
-
11
-
-
0033838426
-
Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin
-
Wang Y, Huang G, Wang J, Molina H, Chaplin DD, Fu YX. Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin. Eur J Immunol 2000;30:2226-2234.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2226-2234
-
-
Wang, Y.1
Huang, G.2
Wang, J.3
Molina, H.4
Chaplin, D.D.5
Fu, Y.X.6
-
12
-
-
77954150116
-
Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses
-
Pereira JP, Kelly LM, Cyster JG. Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses. Int Immunol 2010;22:413-419.
-
(2010)
Int Immunol
, vol.22
, pp. 413-419
-
-
Pereira, J.P.1
Kelly, L.M.2
Cyster, J.G.3
-
13
-
-
0033821807
-
Follicular stromal cells and lymphocyte homing to follicles
-
Cyster JG, et al. Follicular stromal cells and lymphocyte homing to follicles. Immunol Rev 2000;176:181-193.
-
(2000)
Immunol Rev
, vol.176
, pp. 181-193
-
-
Cyster, J.G.1
-
14
-
-
70249085585
-
Stromal cell contributions to the homeostasis and functionality of the immune system
-
Mueller SN, Germain RN. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat Rev Immunol 2009;9:618-629.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 618-629
-
-
Mueller, S.N.1
Germain, R.N.2
-
15
-
-
77958126430
-
B cell follicles and antigen encounters of the third kind
-
Cyster JG. B cell follicles and antigen encounters of the third kind. Nat Immunol 2010;11:989-996.
-
(2010)
Nat Immunol
, vol.11
, pp. 989-996
-
-
Cyster, J.G.1
-
16
-
-
21844450539
-
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
-
e150.
-
Okada T, et al. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol 2005;3:e150.
-
(2005)
PLoS Biol
, vol.3
-
-
Okada, T.1
-
17
-
-
64049084826
-
Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles
-
Coffey F, Alabyev B, Manser T. Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles. Immunity 2009;30:599-609.
-
(2009)
Immunity
, vol.30
, pp. 599-609
-
-
Coffey, F.1
Alabyev, B.2
Manser, T.3
-
18
-
-
68649108084
-
Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses
-
Gatto D, Paus D, Basten A, Mackay CR, Brink R. Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses. Immunity 2009;31:259-269.
-
(2009)
Immunity
, vol.31
, pp. 259-269
-
-
Gatto, D.1
Paus, D.2
Basten, A.3
Mackay, C.R.4
Brink, R.5
-
19
-
-
80053055261
-
EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues
-
Kelly LM, Pereira JP, Yi T, Xu Y, Cyster JG. EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues. J Immunol 2011;187:3026-3032.
-
(2011)
J Immunol
, vol.187
, pp. 3026-3032
-
-
Kelly, L.M.1
Pereira, J.P.2
Yi, T.3
Xu, Y.4
Cyster, J.G.5
-
20
-
-
69349087555
-
EBI2 mediates B cell segregation between the outer and centre follicle
-
Pereira JP, Kelly LM, Xu Y, Cyster JG. EBI2 mediates B cell segregation between the outer and centre follicle. Nature 2009;460:1122-1126.
-
(2009)
Nature
, vol.460
, pp. 1122-1126
-
-
Pereira, J.P.1
Kelly, L.M.2
Xu, Y.3
Cyster, J.G.4
-
21
-
-
79960909447
-
Oxysterols direct immune cell migration via EBI2
-
Hannedouche S, et al. Oxysterols direct immune cell migration via EBI2. Nature 2011;475:524-527.
-
(2011)
Nature
, vol.475
, pp. 524-527
-
-
Hannedouche, S.1
-
22
-
-
79960908110
-
Oxysterols direct B-cell migration through EBI2
-
Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature 2011;475:519-523.
-
(2011)
Nature
, vol.475
, pp. 519-523
-
-
Liu, C.1
-
23
-
-
0032479526
-
Visualization of specific B and T lymphocyte interactions in the lymph node
-
Garside P, Ingulli E, Merica RR, Johnson JG, Noelle RJ, Jenkins MK. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 1998;281:96-99.
-
(1998)
Science
, vol.281
, pp. 96-99
-
-
Garside, P.1
Ingulli, E.2
Merica, R.R.3
Johnson, J.G.4
Noelle, R.J.5
Jenkins, M.K.6
-
24
-
-
79959342619
-
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone
-
Kerfoot SM, et al. Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity 2011;34:947-960.
-
(2011)
Immunity
, vol.34
, pp. 947-960
-
-
Kerfoot, S.M.1
-
25
-
-
79959343565
-
Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity
-
Kitano M, et al. Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity. Immunity 2011;34:961-972.
-
(2011)
Immunity
, vol.34
, pp. 961-972
-
-
Kitano, M.1
-
26
-
-
77649222742
-
Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells
-
Basso K, et al. Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. Blood 2010;115:975-984.
-
(2010)
Blood
, vol.115
, pp. 975-984
-
-
Basso, K.1
-
27
-
-
0034802541
-
Signatures of the immune response
-
Shaffer AL, et al. Signatures of the immune response. Immunity 2001; 15:375-385.
-
(2001)
Immunity
, vol.15
, pp. 375-385
-
-
Shaffer, A.L.1
-
28
-
-
0034691531
-
A chemokine-driven positive feedback loop organizes lymphoid follicles
-
Ansel KM, et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000;406:309-314.
-
(2000)
Nature
, vol.406
, pp. 309-314
-
-
Ansel, K.M.1
-
29
-
-
0033955708
-
CXCR5-deficient mice develop functional germinal centers in the splenic T cell zone
-
Voigt I, Camacho SA, de Boer BA, Lipp M, Forster R, Berek C. CXCR5-deficient mice develop functional germinal centers in the splenic T cell zone. Eur J Immunol 2000;30:560-567.
-
(2000)
Eur J Immunol
, vol.30
, pp. 560-567
-
-
Voigt, I.1
Camacho, S.A.2
de Boer, B.A.3
Lipp, M.4
Forster, R.5
Berek, C.6
-
30
-
-
39649094515
-
Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function
-
Allen CD, Cyster JG. Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin Immunol 2008;20:14-25.
-
(2008)
Semin Immunol
, vol.20
, pp. 14-25
-
-
Allen, C.D.1
Cyster, J.G.2
-
31
-
-
84862908273
-
Follicular dendritic cells help establish follicle identitiy and promote B cell retention in germinal centers
-
Wang X, et al.. Follicular dendritic cells help establish follicle identitiy and promote B cell retention in germinal centers. J Exp Med 2011;208:2497-2510.
-
(2011)
J Exp Med
, vol.208
, pp. 2497-2510
-
-
Wang, X.1
-
32
-
-
79959377393
-
The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement
-
Green JA, et al. The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement. Nat Immunol 2011;12:672-680.
-
(2011)
Nat Immunol
, vol.12
, pp. 672-680
-
-
Green, J.A.1
-
33
-
-
79957610938
-
The outs and the ins of sphingosine-1-phosphate in immunity
-
Spiegel S, Milstien S. The outs and the ins of sphingosine-1-phosphate in immunity. Nat Rev Immunol 2011;11:403-415.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 403-415
-
-
Spiegel, S.1
Milstien, S.2
-
34
-
-
36248956701
-
Finding a way out: lymphocyte egress from lymphoid organs
-
Schwab SR, Cyster JG. Finding a way out: lymphocyte egress from lymphoid organs. Nat Immunol 2007;8:1295-1301.
-
(2007)
Nat Immunol
, vol.8
, pp. 1295-1301
-
-
Schwab, S.R.1
Cyster, J.G.2
-
35
-
-
38449083151
-
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation
-
Bhattacharya D, et al. Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation. J Immunol 2007;179:6808-6819.
-
(2007)
J Immunol
, vol.179
, pp. 6808-6819
-
-
Bhattacharya, D.1
-
36
-
-
12544253058
-
Structural and functional characteristics of S1P receptors
-
Sanchez T, Hla T. Structural and functional characteristics of S1P receptors. J Cell Biochem 2004;92:913-922.
-
(2004)
J Cell Biochem
, vol.92
, pp. 913-922
-
-
Sanchez, T.1
Hla, T.2
-
37
-
-
20144363126
-
The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation
-
Goparaju SK, et al. The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation. Mol Cell Biol 2005;25:4237-4249.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4237-4249
-
-
Goparaju, S.K.1
-
38
-
-
18144420388
-
The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration
-
Lepley D, Paik JH, Hla T, Ferrer F. The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration. Cancer Res 2005;65:3788-3795.
-
(2005)
Cancer Res
, vol.65
, pp. 3788-3795
-
-
Lepley, D.1
Paik, J.H.2
Hla, T.3
Ferrer, F.4
-
39
-
-
0034462185
-
Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3
-
Okamoto H, et al. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. Mol Cell Biol 2000;20:9247-9261.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9247-9261
-
-
Okamoto, H.1
-
40
-
-
0037370012
-
Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
-
Sugimoto N, Takuwa N, Okamoto H, Sakurada S, Takuwa Y. Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform. Mol Cell Biol 2003;23:1534-1545.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1534-1545
-
-
Sugimoto, N.1
Takuwa, N.2
Okamoto, H.3
Sakurada, S.4
Takuwa, Y.5
-
41
-
-
52449133460
-
G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase
-
Takashima S, et al. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase. Cardiovasc Res 2008;79:689-697.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 689-697
-
-
Takashima, S.1
-
43
-
-
17944375813
-
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
-
Fukui Y, et al. Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature 2001;412:826-831.
-
(2001)
Nature
, vol.412
, pp. 826-831
-
-
Fukui, Y.1
-
44
-
-
4444335344
-
Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing
-
Nombela-Arrieta C, et al. Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing. Immunity 2004;21:429-441.
-
(2004)
Immunity
, vol.21
, pp. 429-441
-
-
Nombela-Arrieta, C.1
-
45
-
-
0036672791
-
The CDM protein DOCK2 in lymphocyte migration
-
Reif K, Cyster J. The CDM protein DOCK2 in lymphocyte migration. Trends Cell Biol 2002;12:368-373.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 368-373
-
-
Reif, K.1
Cyster, J.2
-
46
-
-
0037155727
-
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
-
Welch HC, et al. P-Rex1, a PtdIns(3, 4, 5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell 2002;108:809-821.
-
(2002)
Cell
, vol.108
, pp. 809-821
-
-
Welch, H.C.1
-
47
-
-
27944479854
-
Rho GTPases: biochemistry and biology
-
Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005;21:247-269.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
48
-
-
0032568868
-
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13
-
Hart MJ, et al. Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science 1998;280:2112-2114.
-
(1998)
Science
, vol.280
, pp. 2112-2114
-
-
Hart, M.J.1
-
49
-
-
0033604638
-
Signaling to Rho GTPases
-
Kjoller L, Hall A. Signaling to Rho GTPases. Exp Cell Res 1999;253:166-179.
-
(1999)
Exp Cell Res
, vol.253
, pp. 166-179
-
-
Kjoller, L.1
Hall, A.2
-
50
-
-
0345731237
-
Cell migration: Rho GTPases lead the way
-
Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004;265:23-32.
-
(2004)
Dev Biol
, vol.265
, pp. 23-32
-
-
Raftopoulou, M.1
Hall, A.2
-
51
-
-
33746658154
-
FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling
-
Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006;8:803-814.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 803-814
-
-
Ohta, Y.1
Hartwig, J.H.2
Stossel, T.P.3
-
52
-
-
54549088877
-
Rac activation and inactivation control plasticity of tumor cell movement
-
Sanz-Moreno V, et al. Rac activation and inactivation control plasticity of tumor cell movement. Cell 2008;135:510-523.
-
(2008)
Cell
, vol.135
, pp. 510-523
-
-
Sanz-Moreno, V.1
-
53
-
-
34247379074
-
Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
-
Pappu R, et al. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 2007;316:295-298.
-
(2007)
Science
, vol.316
, pp. 295-298
-
-
Pappu, R.1
-
54
-
-
24644469502
-
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
-
Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science 2005;309:1735-1739.
-
(2005)
Science
, vol.309
, pp. 1735-1739
-
-
Schwab, S.R.1
Pereira, J.P.2
Matloubian, M.3
Xu, Y.4
Huang, Y.5
Cyster, J.G.6
-
55
-
-
84859385704
-
Sphingosine-1-phosphates and lymphocyte egress from lymphoid organs
-
Cyster JG, Schwab SR. Sphingosine-1-phosphates and lymphocyte egress from lymphoid organs. Annu Rev Immunol 2012;30:???-??? in press.
-
(2012)
Annu Rev Immunol
, vol.30
-
-
Cyster, J.G.1
Schwab, S.R.2
-
56
-
-
41449112571
-
Vascular endothelium as a contributor of plasma sphingosine 1-phosphate
-
Venkataraman K, et al. Vascular endothelium as a contributor of plasma sphingosine 1-phosphate. Circ Res 2008;102:669-676.
-
(2008)
Circ Res
, vol.102
, pp. 669-676
-
-
Venkataraman, K.1
-
57
-
-
76149126108
-
Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
-
Pham TH, et al. Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. J Exp Med 2010;207:17-27.
-
(2010)
J Exp Med
, vol.207
, pp. 17-27
-
-
Pham, T.H.1
-
58
-
-
79958257954
-
Lipid phosphate phosphatase 3 enables efficient thymic egress
-
Breart B, et al. Lipid phosphate phosphatase 3 enables efficient thymic egress. J Exp Med 2011;208:1267-1278.
-
(2011)
J Exp Med
, vol.208
, pp. 1267-1278
-
-
Breart, B.1
-
59
-
-
62049084843
-
B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis
-
Sinha RK, Park C, Hwang IY, Davis MD, Kehrl JH. B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis. Immunity 2009;30:434-446.
-
(2009)
Immunity
, vol.30
, pp. 434-446
-
-
Sinha, R.K.1
Park, C.2
Hwang, I.Y.3
Davis, M.D.4
Kehrl, J.H.5
-
60
-
-
34147178810
-
Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes
-
Ito K, et al. Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes. Biochem Biophys Res Commun 2007;357:212-217.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 212-217
-
-
Ito, K.1
-
61
-
-
4644219817
-
Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
-
Allen CD, et al. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol 2004;5:943-952.
-
(2004)
Nat Immunol
, vol.5
, pp. 943-952
-
-
Allen, C.D.1
-
62
-
-
0030938635
-
Lymphotoxin-alpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers
-
Matsumoto M, Fu YX, Molina H, Chaplin DD. Lymphotoxin-alpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers. Immunol Rev 1997;156:137-144.
-
(1997)
Immunol Rev
, vol.156
, pp. 137-144
-
-
Matsumoto, M.1
Fu, Y.X.2
Molina, H.3
Chaplin, D.D.4
-
63
-
-
0033521542
-
Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells
-
Endres R, et al. Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. J Exp Med 1999;189:159-168.
-
(1999)
J Exp Med
, vol.189
, pp. 159-168
-
-
Endres, R.1
-
64
-
-
0033579821
-
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen
-
Ngo VN, et al. Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med 1999;189:403-412.
-
(1999)
J Exp Med
, vol.189
, pp. 403-412
-
-
Ngo, V.N.1
-
65
-
-
33846635838
-
Imaging of germinal center selection events during affinity maturation
-
Allen CD, Okada T, Tang HL, Cyster JG. Imaging of germinal center selection events during affinity maturation. Science 2007;315:528-531.
-
(2007)
Science
, vol.315
, pp. 528-531
-
-
Allen, C.D.1
Okada, T.2
Tang, H.L.3
Cyster, J.G.4
-
66
-
-
34248585765
-
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns
-
Hauser AE, et al. Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity 2007;26:655-667.
-
(2007)
Immunity
, vol.26
, pp. 655-667
-
-
Hauser, A.E.1
-
67
-
-
33847206141
-
In vivo imaging of germinal centres reveals a dynamic open structure
-
Schwickert TA, et al. In vivo imaging of germinal centres reveals a dynamic open structure. Nature 2007;446:83-87.
-
(2007)
Nature
, vol.446
, pp. 83-87
-
-
Schwickert, T.A.1
-
68
-
-
78149477766
-
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
-
Victora GD, et al. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 2010;143:592-605.
-
(2010)
Cell
, vol.143
, pp. 592-605
-
-
Victora, G.D.1
-
69
-
-
10244261528
-
Tracking CD40 signaling during germinal center development
-
Basso K, et al. Tracking CD40 signaling during germinal center development. Blood 2004;104:4088-4096.
-
(2004)
Blood
, vol.104
, pp. 4088-4096
-
-
Basso, K.1
-
71
-
-
67649221652
-
Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
-
Phan TG, Green JA, Gray EE, Xu Y, Cyster JG. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol 2009;10:786-793.
-
(2009)
Nat Immunol
, vol.10
, pp. 786-793
-
-
Phan, T.G.1
Green, J.A.2
Gray, E.E.3
Xu, Y.4
Cyster, J.G.5
-
72
-
-
80052649061
-
Cutting edge: distinct waves of BCL6 expression during T follicular helper cell development
-
Baumjohann D, Okada T, Ansel KM. Cutting edge: distinct waves of BCL6 expression during T follicular helper cell development. J Immunol 2011;187:2089-2092.
-
(2011)
J Immunol
, vol.187
, pp. 2089-2092
-
-
Baumjohann, D.1
Okada, T.2
Ansel, K.M.3
-
73
-
-
38049144850
-
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
-
Haynes NM, Allen CD, Lesley R, Ansel KM, Killeen N, Cyster JG. Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. J Immunol 2007;179:5099-5108.
-
(2007)
J Immunol
, vol.179
, pp. 5099-5108
-
-
Haynes, N.M.1
Allen, C.D.2
Lesley, R.3
Ansel, K.M.4
Killeen, N.5
Cyster, J.G.6
-
74
-
-
33846400415
-
The germinal center response is impaired in the absence of T cell-expressed CXCR5
-
Arnold CN, Campbell DJ, Lipp M, Butcher EC. The germinal center response is impaired in the absence of T cell-expressed CXCR5. Eur J Immunol 2007;37:100-109.
-
(2007)
Eur J Immunol
, vol.37
, pp. 100-109
-
-
Arnold, C.N.1
Campbell, D.J.2
Lipp, M.3
Butcher, E.C.4
-
75
-
-
24744448228
-
Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help
-
Hardtke S, Ohl L, Forster R. Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help. Blood 2005;106:1924-1931.
-
(2005)
Blood
, vol.106
, pp. 1924-1931
-
-
Hardtke, S.1
Ohl, L.2
Forster, R.3
-
76
-
-
76949091588
-
Optimal germinal center responses require a multistage T cell: B cell adhesion process involving integrins, SLAM-associated protein, and CD84
-
Cannons JL, et al. Optimal germinal center responses require a multistage T cell: B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity 2010;32:253-265.
-
(2010)
Immunity
, vol.32
, pp. 253-265
-
-
Cannons, J.L.1
-
77
-
-
53649107278
-
SAP-controlled T-B cell interactions underlie germinal centre formation
-
Qi H, Cannons JL, Klauschen F, Schwartzberg PL, Germain RN. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 2008;455:764-769.
-
(2008)
Nature
, vol.455
, pp. 764-769
-
-
Qi, H.1
Cannons, J.L.2
Klauschen, F.3
Schwartzberg, P.L.4
Germain, R.N.5
-
78
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
Johnston RJ, et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 2009;325:1006-1010.
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
-
79
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
Nurieva RI, et al. Bcl6 mediates the development of T follicular helper cells. Science 2009;325:1001-1005.
-
(2009)
Science
, vol.325
, pp. 1001-1005
-
-
Nurieva, R.I.1
-
80
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
Yu D, et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 2009;31:457-468.
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
-
81
-
-
72249096210
-
Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation
-
Cattoretti G, et al. Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation. Cancer Res 2009;69:8686-8692.
-
(2009)
Cancer Res
, vol.69
, pp. 8686-8692
-
-
Cattoretti, G.1
-
82
-
-
15444373513
-
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
-
Sanchez T, et al. PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proc Natl Acad Sci USA 2005;102:4312-4317.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4312-4317
-
-
Sanchez, T.1
-
83
-
-
20244379418
-
Regulation of PTEN by Rho small GTPases
-
Li Z, et al. Regulation of PTEN by Rho small GTPases. Nat Cell Biol 2005;7:399-404.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 399-404
-
-
Li, Z.1
-
84
-
-
0033912699
-
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
-
Genot EM, Arrieumerlou C, Ku G, Burgering BM, Weiss A, Kramer IM. The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol Cell Biol 2000;20:5469-5478.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5469-5478
-
-
Genot, E.M.1
Arrieumerlou, C.2
Ku, G.3
Burgering, B.M.4
Weiss, A.5
Kramer, I.M.6
-
85
-
-
33645644184
-
Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells
-
Gonzalez E, Kou R, Michel T. Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells. J Biol Chem 2006;281:3210-3216.
-
(2006)
J Biol Chem
, vol.281
, pp. 3210-3216
-
-
Gonzalez, E.1
Kou, R.2
Michel, T.3
-
86
-
-
0035846549
-
Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells
-
Higuchi M, Masuyama N, Fukui Y, Suzuki A, Gotoh Y. Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells. Curr Biol 2001;11:1958-1962.
-
(2001)
Curr Biol
, vol.11
, pp. 1958-1962
-
-
Higuchi, M.1
Masuyama, N.2
Fukui, Y.3
Suzuki, A.4
Gotoh, Y.5
-
87
-
-
53149135853
-
Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII
-
Jiang LI, Collins J, Davis R, Fraser ID, Sternweis PC. Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII. J Biol Chem 2008;283:23429-23439.
-
(2008)
J Biol Chem
, vol.283
, pp. 23429-23439
-
-
Jiang, L.I.1
Collins, J.2
Davis, R.3
Fraser, I.D.4
Sternweis, P.C.5
-
88
-
-
0037192820
-
Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation
-
Mei FC, Qiao J, Tsygankova OM, Meinkoth JL, Quilliam LA, Cheng X. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. J Biol Chem 2002;277:11497-11504.
-
(2002)
J Biol Chem
, vol.277
, pp. 11497-11504
-
-
Mei, F.C.1
Qiao, J.2
Tsygankova, O.M.3
Meinkoth, J.L.4
Quilliam, L.A.5
Cheng, X.6
-
89
-
-
77949332336
-
Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation
-
Michaud J, Im DS, Hla T. Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation. J Immunol 2010;184:1475-1483.
-
(2010)
J Immunol
, vol.184
, pp. 1475-1483
-
-
Michaud, J.1
Im, D.S.2
Hla, T.3
-
90
-
-
70149094600
-
AID constrains germinal center size by rendering B cells susceptible to apoptosis
-
Zaheen A, Boulianne B, Parsa JY, Ramachandran S, Gommerman JL, Martin A. AID constrains germinal center size by rendering B cells susceptible to apoptosis. Blood 2009;114:547-554.
-
(2009)
Blood
, vol.114
, pp. 547-554
-
-
Zaheen, A.1
Boulianne, B.2
Parsa, J.Y.3
Ramachandran, S.4
Gommerman, J.L.5
Martin, A.6
-
91
-
-
1542377328
-
B cell receptor signal strength determines B cell fate
-
Casola S, et al. B cell receptor signal strength determines B cell fate. Nat Immunol 2004;5:317-327.
-
(2004)
Nat Immunol
, vol.5
, pp. 317-327
-
-
Casola, S.1
-
92
-
-
33749168166
-
B cell recruitment and selection in mouse GALT germinal centers
-
Casola S, Rajewsky K. B cell recruitment and selection in mouse GALT germinal centers. Curr Top Microbiol Immunol 2006;308:155-171.
-
(2006)
Curr Top Microbiol Immunol
, vol.308
, pp. 155-171
-
-
Casola, S.1
Rajewsky, K.2
-
93
-
-
0343932758
-
CD19-deficient mice exhibit poor responsiveness to oral immunization despite evidence of unaltered total IgA levels, germinal centers and IgA-isotype switching in Peyer's patches
-
Gardby E, Lycke NY. CD19-deficient mice exhibit poor responsiveness to oral immunization despite evidence of unaltered total IgA levels, germinal centers and IgA-isotype switching in Peyer's patches. Eur J Immunol 2000;30:1861-1871.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1861-1871
-
-
Gardby, E.1
Lycke, N.Y.2
-
94
-
-
0037342166
-
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
-
Anzelon AN, Wu H, Rickert RC. Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nat Immunol 2003;4:287-294.
-
(2003)
Nat Immunol
, vol.4
, pp. 287-294
-
-
Anzelon, A.N.1
Wu, H.2
Rickert, R.C.3
-
95
-
-
20444501371
-
CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers
-
Wang Y, Carter RH. CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers. Immunity 2005;22:749-761.
-
(2005)
Immunity
, vol.22
, pp. 749-761
-
-
Wang, Y.1
Carter, R.H.2
-
96
-
-
0037119630
-
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation
-
Clayton E, et al. A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med 2002;196:753-763.
-
(2002)
J Exp Med
, vol.196
, pp. 753-763
-
-
Clayton, E.1
-
97
-
-
0037695593
-
Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex
-
Jou ST, et al. Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Mol Cell Biol 2002;22:8580-8591.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8580-8591
-
-
Jou, S.T.1
-
98
-
-
0037047590
-
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice
-
Okkenhaug K, et al. Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Science 2002;297:1031-1034.
-
(2002)
Science
, vol.297
, pp. 1031-1034
-
-
Okkenhaug, K.1
-
99
-
-
77958134778
-
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction
-
Rolf J, et al. Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol 2010;185:4042-4052.
-
(2010)
J Immunol
, vol.185
, pp. 4042-4052
-
-
Rolf, J.1
-
100
-
-
4344671730
-
Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus
-
Vigorito E, Bardi G, Glassford J, Lam EW, Clayton E, Turner M. Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus. J Immunol 2004;173:3209-3214.
-
(2004)
J Immunol
, vol.173
, pp. 3209-3214
-
-
Vigorito, E.1
Bardi, G.2
Glassford, J.3
Lam, E.W.4
Clayton, E.5
Turner, M.6
-
101
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
Srinivasan L, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell 2009;139:573-586.
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
-
102
-
-
40449110080
-
The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells
-
Janas ML, et al. The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. J Immunol 2008;180:739-746.
-
(2008)
J Immunol
, vol.180
, pp. 739-746
-
-
Janas, M.L.1
-
103
-
-
77956636063
-
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development
-
ra60.
-
Ramadani F, et al. The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development. Sci Signal 2010;3:ra60.
-
(2010)
Sci Signal
, vol.3
-
-
Ramadani, F.1
-
104
-
-
46149106818
-
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma
-
Guillermet-Guibert J, et al. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci USA 2008;105:8292-8297.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8292-8297
-
-
Guillermet-Guibert, J.1
-
105
-
-
4043082729
-
Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing
-
Reif K, Okkenhaug K, Sasaki T, Penninger JM, Vanhaesebroeck B, Cyster JG. Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing. J Immunol 2004;173:2236-2240.
-
(2004)
J Immunol
, vol.173
, pp. 2236-2240
-
-
Reif, K.1
Okkenhaug, K.2
Sasaki, T.3
Penninger, J.M.4
Vanhaesebroeck, B.5
Cyster, J.G.6
-
106
-
-
70449718702
-
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
-
Randall KL, et al. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production. Nat Immunol 2009;10:1283-1291.
-
(2009)
Nat Immunol
, vol.10
, pp. 1283-1291
-
-
Randall, K.L.1
-
107
-
-
77953643796
-
Bam32/DAPP1 promotes B cell adhesion and formation of polarized conjugates with T cells
-
Al-Alwan M, Hou S, Zhang TT, Makondo K, Marshall AJ. Bam32/DAPP1 promotes B cell adhesion and formation of polarized conjugates with T cells. J Immunol 2010;184:6961-6969.
-
(2010)
J Immunol
, vol.184
, pp. 6961-6969
-
-
Al-Alwan, M.1
Hou, S.2
Zhang, T.T.3
Makondo, K.4
Marshall, A.J.5
-
108
-
-
73949091167
-
The pleckstrin homology domain adaptor protein Bam32/DAPP1 is required for germinal center progression
-
Zhang TT, Al-Alwan M, Marshall AJ. The pleckstrin homology domain adaptor protein Bam32/DAPP1 is required for germinal center progression. J Immunol 2010;184:164-172.
-
(2010)
J Immunol
, vol.184
, pp. 164-172
-
-
Zhang, T.T.1
Al-Alwan, M.2
Marshall, A.J.3
-
109
-
-
77954913409
-
Control systems and decision making for antibody production
-
Goodnow CC, Vinuesa CG, Randall KL, Mackay F, Brink R. Control systems and decision making for antibody production. Nat Immunol 2010;11:681-688.
-
(2010)
Nat Immunol
, vol.11
, pp. 681-688
-
-
Goodnow, C.C.1
Vinuesa, C.G.2
Randall, K.L.3
Mackay, F.4
Brink, R.5
-
110
-
-
17344362824
-
Cell growth control by G protein-coupled receptors: from signal transduction to signal integration
-
Gutkind JS. Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 1998;17:1331-1342.
-
(1998)
Oncogene
, vol.17
, pp. 1331-1342
-
-
Gutkind, J.S.1
-
111
-
-
0032563295
-
Activation of Akt/protein kinase B by G protein-coupled receptors: a role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma
-
Murga C, Laguinge L, Wetzker R, Cuadrado A, Gutkind JS. Activation of Akt/protein kinase B by G protein-coupled receptors: a role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma. J Biol Chem 1998;273:19080-19085.
-
(1998)
J Biol Chem
, vol.273
, pp. 19080-19085
-
-
Murga, C.1
Laguinge, L.2
Wetzker, R.3
Cuadrado, A.4
Gutkind, J.S.5
-
113
-
-
0033486065
-
The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes
-
Sotsios Y, Whittaker GC, Westwick J, Ward SG. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol 1999;163:5954-5963.
-
(1999)
J Immunol
, vol.163
, pp. 5954-5963
-
-
Sotsios, Y.1
Whittaker, G.C.2
Westwick, J.3
Ward, S.G.4
-
114
-
-
0034618052
-
Signal transduction by CXC chemokine receptor 4 Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes
-
Tilton B, et al. Signal transduction by CXC chemokine receptor 4 Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. J Exp Med 2000;192:313-324.
-
(2000)
J Exp Med
, vol.192
, pp. 313-324
-
-
Tilton, B.1
-
115
-
-
0035839450
-
A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation
-
Arron JR, et al. A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation. J Biol Chem 2001;276:30011-30017.
-
(2001)
J Biol Chem
, vol.276
, pp. 30011-30017
-
-
Arron, J.R.1
-
117
-
-
34548390650
-
IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade
-
Ostiguy V, Allard EL, Marquis M, Leignadier J, Labrecque N. IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade. J Leukoc Biol 2007;82:645-656.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 645-656
-
-
Ostiguy, V.1
Allard, E.L.2
Marquis, M.3
Leignadier, J.4
Labrecque, N.5
-
118
-
-
34248364008
-
The molecular basis of IL-21-mediated proliferation
-
Zeng R, Spolski R, Casas E, Zhu W, Levy DE, Leonard WJ. The molecular basis of IL-21-mediated proliferation. Blood 2007;109:4135-4142.
-
(2007)
Blood
, vol.109
, pp. 4135-4142
-
-
Zeng, R.1
Spolski, R.2
Casas, E.3
Zhu, W.4
Levy, D.E.5
Leonard, W.J.6
-
119
-
-
79251542927
-
Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1
-
Joung SM, Park ZY, Rani S, Takeuchi O, Akira S, Lee JY. Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1. J Immunol 2011;186:499-507.
-
(2011)
J Immunol
, vol.186
, pp. 499-507
-
-
Joung, S.M.1
Park, Z.Y.2
Rani, S.3
Takeuchi, O.4
Akira, S.5
Lee, J.Y.6
-
120
-
-
0141844653
-
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
-
Lee JY, et al. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. J Biol Chem 2003;278:37041-37051.
-
(2003)
J Biol Chem
, vol.278
, pp. 37041-37051
-
-
Lee, J.Y.1
-
121
-
-
33845709678
-
An essential role for Akt1 in dendritic cell function and tumor immunotherapy
-
Park D, Lapteva N, Seethammagari M, Slawin KM, Spencer DM. An essential role for Akt1 in dendritic cell function and tumor immunotherapy. Nat Biotechnol 2006;24:1581-1590.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1581-1590
-
-
Park, D.1
Lapteva, N.2
Seethammagari, M.3
Slawin, K.M.4
Spencer, D.M.5
-
122
-
-
33746926779
-
Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice
-
Michaud J, Kohno M, Proia RL, Hla T. Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice. FEBS Lett 2006;580:4607-4612.
-
(2006)
FEBS Lett
, vol.580
, pp. 4607-4612
-
-
Michaud, J.1
Kohno, M.2
Proia, R.L.3
Hla, T.4
-
123
-
-
78650866759
-
Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis
-
Skoura A, et al. Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol 2011;31:81-85.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 81-85
-
-
Skoura, A.1
-
124
-
-
78049422010
-
Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice
-
Wang F, et al. Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J Clin Invest 2010;120:3979-3995.
-
(2010)
J Clin Invest
, vol.120
, pp. 3979-3995
-
-
Wang, F.1
-
125
-
-
78650413566
-
Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo
-
Ishii M, Kikuta J, Shimazu Y, Meier-Schellersheim M, Germain RN. Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo. J Exp Med 2010;207:2793-2798.
-
(2010)
J Exp Med
, vol.207
, pp. 2793-2798
-
-
Ishii, M.1
Kikuta, J.2
Shimazu, Y.3
Meier-Schellersheim, M.4
Germain, R.N.5
-
126
-
-
1842682019
-
Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis
-
Jolly PS, et al. Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis. J Exp Med 2004;199:959-970.
-
(2004)
J Exp Med
, vol.199
, pp. 959-970
-
-
Jolly, P.S.1
-
127
-
-
77949518621
-
Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema
-
Oskeritzian CA, et al. Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema. J Exp Med 2010;207:465-474.
-
(2010)
J Exp Med
, vol.207
, pp. 465-474
-
-
Oskeritzian, C.A.1
-
128
-
-
22244480680
-
Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane
-
Nishida K, et al. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol 2005;170:115-126.
-
(2005)
J Cell Biol
, vol.170
, pp. 115-126
-
-
Nishida, K.1
|