Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

Nature Immunology

Volumn 10, Issue 7, 2009, Pages 786-796

  Phan, Tri Giang ^a,b   Green, Jesse A ^a   Xu, Ying ^a   Cyster, Jason G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYAN FLUORESCENT PROTEIN; LYMPHOTOXIN ALPHA BETA; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOME ENZYME;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL ISOLATION; CELL MATURATION; CONTROLLED STUDY; ENDOSOME; GENE EXPRESSION; HUMORAL IMMUNITY; IMMUNE RESPONSE; MACROPHAGE; MOUSE; NONCOGNATE B CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBCAPSULAR SINUS MACROPHAGE;

ANIMALS; ANTIBODIES; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY COMPLEX; ANTIGEN-PRESENTING CELLS; ANTIGENS, SURFACE; B-LYMPHOCYTES; CELL DIFFERENTIATION; ENDOCYTOSIS; FLOW CYTOMETRY; GERMINAL CENTER; LYMPH NODES; LYMPHOTOXIN-ALPHA; LYSOSOMES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICROSCOPY, FLUORESCENCE; MURAMIDASE; OPSONIN PROTEINS; PEPTIDE HYDROLASES;

EID: 67649221652     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1745     Document Type: Article

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