Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

Science

Volumn 283, Issue 5403, 1999, Pages 845-848

  Peled, Amnon ^a   Petit, Isabelle ^a   Kollet, Orit ^a   Magid, Michal ^a   Ponomaryov, Tanya ^a   Byk, Tamara ^a   Nagler, Arnon ^e   Ben Hur, Herzl ^b   Many, Ariel ^c   Shultz, Leonard ^d   Lider, Ofer ^a   Alon, Ronen ^a   Zipori, Dov ^a   Lapidot, Tsvee ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b KAPLAN MEDICAL CENTER   (Israel)

^c TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^d JACKSON LABORATORY   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; HELPER CELL; HEMATOPOIESIS; HUMAN; HUMAN CELL; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; T LYMPHOCYTE SUBPOPULATION;

ADP-RIBOSYL CYCLASE; ANIMALS; ANTIBODIES; ANTIGENS, CD; ANTIGENS, CD34; ANTIGENS, CD38; ANTIGENS, DIFFERENTIATION; CHEMOKINES, CXC; CHEMOTAXIS; COLONY-FORMING UNITS ASSAY; FETAL BLOOD; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-6; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; NAD+ NUCLEOSIDASE; RECEPTORS, CXCR4; STEM CELL FACTOR; TETRADECANOYLPHORBOL ACETATE; UP-REGULATION;

ANIMALIA; MURINAE;

EID: 0033524834     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5403.845     Document Type: Article

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24. Supported by grants from the Israel Academy of Science and the Israel Cancer Research Fund (T.L), the Germany MINERVA grant (A.P.), a grant from the Balfour Peisner Bone Marrow Cancer Research Fund (I.P). a grant from the Israel Ministry of Science (O.K.), and NIH grant A130389 (L.S.). We thank Y. Yarden, E. Canaani, M. Revel, P. Lonai, M. Feldman, and A. B. David for critically reviewing this manuscript and J. Dick for NOD/SCID mice, his pluripotent help and support, and for critically reviewing the revised version of the manuscript.