Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses

Journal of Immunology

Volumn 170, Issue 2, 2003, Pages 686-694

  Tangye, Stuart G ^a   Avery, Danielle T ^a   Deenick, Elissa K ^a   Hodgkin, Philip D ^a  

^a CENTENARY INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; CD40 LIGAND; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 2;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOLOGICAL MEMORY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0037438633     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.2.686     Document Type: Article

References (51)

1. Liu, Y. J., S. Oldfield, and I. C. MacLennan. 1988. Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones. Eur. J. Immunol. 18:355.
2. Liu, Y. J., J. Zhang, P. J. Lane, E. Y. Chan, and I. C. MacLennan. 1991. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J Immunol. 21:2951.
3. Liu, Y. J., and J. Banchereau. 1996. The paths and molecular controls of peripheral B-cell development. Immunologist 4:55.
4. Smith, K. G., T. D. Hewitson, G. J. Nossal, and D. M. Tarlinton. 1996. The phenotype and fate of the antibody-forming cells of the splenic foci. J. Ommunol. 26:444.
5. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
6. Klein, U., R. Kuppers, and K. Rajewsky. 1997. Evidence for a large compartment of IgM-expressing memory B cells in humans. Blood 89:1288.
7. + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 188:1679.
8. Paramithiotis, E., and M. D. Cooper. 1997. Memory B lymphocytes migrate to bone marrow in humans. Proc. Natl. Acad. Sci. USA 94:208.
9. Dunn-Walters, D. K., P. G. Isaacson, and J. Spencer, 1995. Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J. Exp. Med. 182:559.
10. Tangye, S. G., Y. J. Liu, G. Aversa, J. H. Phillips, and J. E. de Vries. 1998. Identification of functional human splenic memory B cells by expression of CD148 and CD27. J. Exp. Med. 188:1691.
11. Liu, Y. J., C. Barthelemy, O. de Bouteiller, C. Arpin, I. Durand, and J. Banchereau. 1995. Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T ceils by rapid up-regulation of B7-1 and B7-2. Immunity 2:239.
12. 7 and E-selectin ligand by circulating memory B cells: implications for targeted trafficking to mucosal and systemic sites. J. Leukocyte Biol. 68:807.
13. Tangye, S. G., B. C. M. van de Weerdt, D. T. Avery, and P. D. Hodgkin. 2002. CD84 is upregulated on a major population of human memory B cells and recruits the SH2-domain containing proteins SAP and EAT-2. Eur. J. Immunol. 32:1640.
14. - memory. B cell compartment. J. Exp. Med. 191:1149.
15. Pihlgren, M., N. Schallert, C. Tougne, P. Bozzotti, J. Kovarik, A. Fulurija, M. Kosco-Vilbois, P. H. Lambert, and C. A. Siegrist. 2001. Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life. Eur. J. Immunol. 31:939.
16. high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J. Immunol. 162:7198.
17. Martin, S. W., and C. C. Goodnow. 2002. Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory. Nat. Immunol. 3:182.
18. Kehry, M. R., and P. D. Hodgkin. 1993. Helper T cells: delivery of cell contact and lymphokine-dependent signals to B cells. Semin. Immunol. 5:393.
19. Tangye, S. G., A. Ferguson, D. T. Avery, C. S. Ma, and P. D. Hodgkin. Isotype switching by human B cells is division-associated and regulated by cytokines. J. Immunol. 169:4298.
20. Lyons, A. B., and C. R. Parish. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171:131.
21. Hodgkin, P. D., J. H. Lee, and A. B. Lyons. 1996. B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184:277.
22. Hodgkin, P. D., N. F. Go, J. E. Cupp, and M. Howard. 1991. Interleukin-4 enhances anti-IgM stimulation of B cells by improving cell viability and by increasing the sensitivity of B cells to the anti-IgM signal. Cell. Immunol. 13:14.
23. + T cells to antigen stimulation in vivo. Nat. Immunol. 1:47.
24. Gett, A. V., and P. D. Hodgkin. 1998. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl. Acad. Sci. USA 95:9488.
25. Hasbold, J., A. B. Lyons, M. R. Kehry, and P. D. Hodgkin. 1998. Cell division number regulates IgGI and IgE switching of B cells following stimulation by CD40 ligand and IL-4. Eur J. Immunol. 28:1040.
26. Arpin, C., J. Banchereau, and Y. J. Liu. 1997. Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing. J. Exp. Med. 186:931.
27. Yefenof, E., V. M. Sanders, J. W. Uhr, and E. S. Vitetta. 1986. In vitro activation of murine antigen-specific memory B cells by a T-dependent antigen. J. Immunol. 137:85.
28. low T cells. Eur. J. Immunol. 24:2993.
29. Fluckiger, A. C., P. Garrone. I. Durand, J. P. Galizzi, and J. Banchereau. 1993. Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. J. Exp. Med. 178:1473.
30. Snapper, C. M., H. Yamada, D. Smoot, R. Sneed, A. Lees, and J. J. Mond. 1993. Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells. J. Immunol. 150:2737.
31. Oliver, A. M., F. Martin, G. L. Gartland, R. H. Carter, and J. F. Kearney. 1997. Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses. Eur. J. Immunol. 27:2366.
32. Martin, F., A. M. Oliver, and J. F. Kearney. 2001. Marginal zone and BI B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617.
33. Li, X., F. Martin, A. M. Oliver, J. F. Kearney, and R. H. Carter. 2001. Antigen receptor proximal signaling in splenic B-2 cell subsets. J. Immunol. 166:3122.
34. Martin, F., and J. F. Kearney. 2002. Marginal-zone B cells. Nat. Rev. Immunol. 2:323.
35. Lu, T. T., and J. G. Cyster. 2002. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297:409.
36. Wheeler, K., J. D. Pound, J. Gordon, and R. Jefferis. 1993. Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor. Eur. J. Immunol. 23:1165.
37. Axcrona, K., D. Gray, and T. Leanderson. 1996. Regulation of B cell growth and differentiation via CD21 and CD40. Eur. J. Immunol. 26:2203.
38. Dempsey, P. W., M. E. Allison, S. Akkaraju, C. C. Goodnow, and D. T. Fearon. 1996. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Science 271:348.
39. Barrett, T. B., G. Shu, and E. A. Clark. 1991. CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells. J. Immunol. 146:1722.
40. Lane, P. J., F. M. McConnell, E. A. Clark, and E. Mellins. 1991. Rapid signaling to B cells by antigen-specific T cells requires CD18/CD54 interaction. J. Immunol. 147:4103.
41. Tohma, S., S. Hirohata, and P. E. Lipsky. 1991. The role of CD11a/CD18-CD54 interactions in human T cell-dependent B cell activation. J. Immunol. 146:492.
42. Lindhout, E., M. L. Mevissen, J. Kwekkeboom, J. M. Tager, and C. de Groot. 1993. Direct evidence that human follicular dendritic cells (FDC) rescue germinal centre B cells from death by apoptosis. Clin. Exp. Immunol. 91:330.
43. Liu, Y. J., G. Grouard, O. de Bouteiller, and J. Banchereau. 1996. Follicular dendritic cells and germinal centers. Int. Rev. Cytol. 166:139.
44. Kwekkeboom, J., D. de Rijk, A. Kasran, S. Barcy, C. de Groot, and M. de Boer. 1994. Helper effector function of human T cells stimulated by anti-CD3 mAb can be enhanced by co-stimulatory signals and is partially dependent on CD40-CD40 ligand interaction. Eur. J. Immunol. 24:508.
45. Klaus, S. J., L. M. Pinchuk, H. D. Ochs, C. L. Law, W. C. Fanslow, R. J. Armitage, and E. A. Clark. 1994. Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction. J. Immunol. 152: 5643.
46. Fearon, D. T., P. Manders, and S. D. Wagner. 2001. Arrested differentiation, the self-renewing memory lymphocyte, and vaccination. Science 293:248.
47. Calame, K. L. 2001. Plasma cells: finding new light at the end of B cell development. Nat. Immunol. 2:1103.
48. Lin, Y., K. Wong, and K. Calame. 1997. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science 276:596.
49. Angelin-Duclos, C., G. Cattoretti, K. I. Lin, and K. Calame. 2000. Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J. Immunol. 165:5462.
50. Falini, B., M. Fizzotti, A. Pucciarini, B. Bigerna, T. Marafioti, M. Gambacorta, R. Pacini, C. Alunni, L. Natali-Tanci, B. Ugolini, et al. 2000. A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 95:2084.
51. Tangye, S. G., D. T. Avery, and P. D. Hodgkin. A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells. J. Immunol. In Press.