Pilot-scale membrane fractionation of ACE inhibitory and antioxidative peptides from ultrasound pretreated milk protein concentrate hydrolysates

Journal of Functional Foods

Volumn 7, Issue 1, 2014, Pages 350-361

  Uluko, Hankie ^a,b   Zhang, Shuwen ^a   Liu, Lu ^a   Li, Hongjuan ^a   Cui, Wenming ^a   Xue, Haixiao ^a   Zhao, Lili ^a   Sun, Yanjun ^c   Lu, Jing ^a   Lv, Jiaping ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b LILONGWE UNIVERSITY OF AGRICULTURE AND NATURAL RESOURCES   (Malawi)

^c Technical Center   (China)

Author keywords

Angiotensin converting enzyme; Antioxidative; Hydrolysis; Membrane filtration; Milk protein concentrate; Ultrasound

Indexed keywords

EID: 84898022416     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2014.01.025     Document Type: Article

References (56)

1. Arzeni C., Martinez K., Zema P., Arias A., Perez O.E., Pilosof A.M.R. Comparative study of high intensity ultrasound effects on food proteins functionality. Journal of Food Engineering 2012, 108:463-472.
2. Benzie I.F.F., Strain J.J. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Analytical Biochemistry 1996, 239:70-76.
3. Chabeaud A., Vandanjon L., Bourseau P., Jaouen P., Guerard F. Fractionation by ultrafiltration of a saithe protein hydrolysate (Pollachius virens): Effect of material and molecular weight cut-off on the membrane performances. Journal of Food Engineering 2009, 91:408-414.
4. Cisse M., Vaillant F., Pallet D., Dornier M. Selecting ultrafiltration and nanofiltration membranes to concentrate anthocyanins from roselle extract (Hibiscus sabdariffa L.). Food Research International 2011, 44:2607-2614.
5. Clapes P., Pera E., Torres J. Peptide bond formation by the industrial protease, neutrase, in aqueous media. Biotechnology Letters 1997, 19:1023-1026.
6. Contreras M., Carron R., Montero M., Ramos M., Recio I. Novel casein-derived peptides with antihypertensive activity. International Dairy Journal 2009, 19:566-573.
7. Contreras M., Hernandez-Ledesma B., Amigo L., Martín-Álvarez P., Recio I. Production of antioxidant hydrolyzates from a whey protein concentrate with thermolysin: Optimization by response surface methodology. LWT - Food Science and Technology 2011, 44:9-15.
8. Contreras M., Sevilla M.A., Monroy-Ruiz J., Amigo L., Gómez-Sala B., Molina E., Ramos M., Recio I. Food-grade production of an antihypertensive casein hydrolysates and resistance of active peptides to drying and storage. International Dairy Journal 2011, 21:470-476.
9. Dryakova A., Pihlanto A., Marnila P., Curda L., Korhonen H.J.T. Antioxidant properties of whey protein hydrolysates as measured by three methods. European Food Research and Technology 2010, 230:865-874.
10. Dziuba J., Minkiewicz P., Nałecz D., Iwaniak A. Database of biologically active peptide sequences. Nahrung 1999, 43:190-195.
11. Ferreira I.M.P.L.V.O., Pinho O., Mota M.V., Tavares P., Pereira A., Goncalves M.P., Torres D., Rocha C., Teixeira J.A. Preparation of ingredients containing an ACE-inhibitory peptide by tryptic hydrolysis of whey protein concentrates. International Dairy Journal 2007, 17:481-487.
12. Geerlings A., Villar I.C., Zarco F.H., Sanchez M., Vera R., Gomez A.Z., Boza J., Duarte J. Identification and characterization of novel angiotensin-converting enzyme inhibitors obtained from goat milk. Journal of Dairy Science 2006, 89:3326-3335.
13. Girgih A.T., Udenigwe C.C., Li H., Adebiyi A.P., Aluko R.E. Kinetics of enzyme inhibition and antihypertensive effects of hemp seed (Cannabis sativa L.) protein hydrolysates. Journal of the American Oil Chemists' Society 2011, 88:1767-1774.
14. Gomez-Ruiz J.A., Lopez-Exposito I., Pihlanto A., Ramos M., Recio I. Antioxidant activity of ovine casein hydrolysates: Identification of active peptides by HPLC-MS/MS. European Food Research and Technology 2008, 227:1061-1067.
15. Gosch T., Apprich S., Kneifel W., Novalin S. Improved isolation of bioactive components of bovine colostrum using cross-flow microfiltration. International Journal of Dairy Technology 2013, 66:175-181.
16. Gu F., Kim J.M., Abbas S., Zhang X., Xia S., Chen Z. Structure and antioxidant activity of high molecular weight Maillard reaction products from casein-glucose. Food Chemistry 2010, 120:505-511.
17. Guo Y., Pan D., Tanokura M. Optimisation of hydrolysis conditions for the production of the angiotensin-I-converting enzyme (ACE) inhibitory peptides from whey protein using response surface methodology. Food Chemistry 2009, 114:328-333.
18. He R., Girgih A.T., Malomo S.A., Ju X., Aluko R.E. Antioxidant activities of enzymatic rapeseed protein hydrolysates and the membrane ultrafiltration fractions. Journal of Functional Foods 2013, 5:219-227.
19. Hernández-Ledesma B., Contreras M., Recio I. Antihypertensive peptides: Production, bioavailability and incorporation into foods. Advances in Colloid and Interface Science 2011, 165:23-35.
20. Hernandez-Ledesma B., Miralles B., Amigo L., Ramos M., Recio I. Identification of antioxidant and ACE-inhibitory peptides in fermented milk. Journal of the Science of Food and Agriculture 2005, 85:1041-1048.
21. Holder A., Birke A., Eisele T., Klaiber I., Fischer L., Hinrichs J. Selective isolation of angiotensin-I-converting enzyme-inhibitory peptides from micellar casein and b-casein hydrolysates via ultrafiltration. International Dairy Journal 2013, 31:34-40.
22. Huang L., Liu B., Ma H., Zhang X. Combined effect of ultrasound and enzymatic treatments on production of ACE inhibitory peptides from wheat germ protein. Journal of Food Processing and Preservation 2013, 10.1111/jfpp.12125.
23. Igoshi K., Kondo Y., Kobayashi H., Kabata K., Kawakami H. Antioxidative activity of cheese. Milchwissenschaft 2008, 63:424-426.
24. Jakala P., Jauhiainen T., Korpela R., Vapaatalo H. Milk protein-derived bioactive tripeptides Ile-Pro-Pro and Val-Pro-Pro protect endothelial function in vitro in hypertensive rats. Journal of Functional Foods 2009, 1:266-273.
25. Jambrak A.R., Mason T.J., Lelas V., Herceg Z., Herceg I.L. Effect of ultrasound treatment on solubility and foaming properties of whey protein suspensions. Journal of Food Engineering 2008, 86:281-287.
26. Jia J.Q., Ma H.L., Zhao W.R., Wang Z.B., Tian W.M., Luo L., He R.H. The use of ultrasound for enzymatic preparation of ACE-inhibitory peptides from wheat germ protein. Food Chemistry 2010, 119:336-342.
27. Jiang J.L., Chen S.W., Ren F.Z., Luo Z., Zeng S.S. Yak milk casein as a functional ingredient: Preparation and identification of angiotensin-I-converting enzyme inhibitory peptides. Journal of Dairy Research 2007, 74:18-25.
28. Korhonen H. Milk-derived bioactive peptides: From science to applications. Journal of Functional Foods 2009, 1:177-187.
29. Korus A. Effect of technological processing and preservation method on amino acid content and protein quality in kale (Brassica oleracea L. var. acephala) leaves. Journal of the Science of Food and Agriculture 2012, 92:618-625.
30. Kudoh Y., Matsuda S., Igoshi K., Oki T. Antioxidative peptide from milk fermented with Lactobacillus delbrueckii subsp. bulgaricus IFO13953. Journal of the Japanese Society of Food Science 2001, 48:44-50.
31. Lacroix I.M.E., Li-Chan E.C.Y. Dipeptidyl peptidase-IV inhibitory activity of dairy protein hydrolysates. International Dairy Journal 2012, 25:97-102.
32. Lei B., Majumder K., Shen S., Wu J. Effect of sonication on thermolysin hydrolysis of ovotransferrin. Food Chemistry 2011, 124:808-815.
33. Lopez-Exposito I., Quiros A., Amigo L., Recio I. Casein hydrolysates as a source of antimicrobial, antioxidant and antihypertensive peptides. Lait 2007, 87:241-249.
34. Nielsen P.M., Petersen D., Dambmann C. Improved method for determining food protein degree of hydrolysis. Journal of Food Science 2001, 66:642-646.
35. Otte J., Shalaby S.M., Zakora M., Pripp A.H., El-Shabrawy S.A. Angiotensin converting enzyme inhibitory activity of milk protein hydrolysates: Effect of substrate, enzyme and time of hydrolysis. International Dairy Journal 2007, 17:488-503.
36. Pan D., Cao J., Guo H., Zhao B. Studies on purification and the molecular mechanism of a novel ACE inhibitory peptide from whey protein hydrolysate. Food Chemistry 2012, 130:121-126.
37. Panchaud A., Affolter M., Kussmann M. Mass spectrometry for nutritional peptidomics: How to analyze food bioactives and their health effects. Journal of Proteomics 2012, 75:3546-3559.
38. Pihlanto A. Antioxidative peptides derived from milk proteins. International Dairy Journal 2006, 16:1306-1314.
39. Power O., Jakeman P., FitzGerald R.J. Antioxidative peptides: Enzymatic production, in vitro and in vivo antioxidant activity and potential applications of milk-derived antioxidative peptides. Amino Acids 2013, 44:797-820.
40. Qian B., Xing M., Cui L., Deng Y., Xu Y., Huang M., Zhang S. Antioxidant, antihypertensive, and immunomodulatory activities of peptide fractions from fermented skim milk with Lactobacillus delbrueckii ssp. bulgaricus LB340. Journal of Dairy Research 2011, 78:72-79.
41. Quiros A., Ramos M., Muguerza B., Delgado M., Miguel M., Aleixandre A., Recio I. Identification of novel antihypertensive peptides in milk fermented with Enterococcus faecalis. International Dairy Journal 2007, 17:33-41.
42. Qureshi T.M., Vegarud G.E., Abrahamsen R.K., Skeie S. Angiotensin I-converting enzyme-inhibitory activity of the Norwegian autochthonous cheeses Gamalost and Norvegia after in vitro human gastrointestinal digestion. Journal of Dairy Science 2013, 96:1-16.
43. Roblet C., Amiot J., Lavigne C., Marette A., Lessard M., Jean J., Ramassamy C., Moresoli C., Bazinet L. Screening of in vitro bioactivities of a soy protein hydrolysate separated by hollow fiber and spiral-wound ultrafiltration membranes. Food Research International 2012, 46:237-249.
44. Rojas-Ronquillo R., Cruz-Guerrero A., Flores-Nájera A., Rodríguez-Serrano G., Gómez-Ruiz L., Reyes-Grajeda J.P., Jiménez-Guzmán J., García-Garibay M. Antithrombotic and angiotensin-converting enzyme inhibitory properties of peptides released from bovine casein by Lactobacillus casei Shirota. International Dairy Journal 2012, 26:147-154.
45. Samaranayaka A.G.P., Li-Chan E.C.Y. Food-derived peptidic antioxidants: A review of their production, assessment, and potential applications. Journal of Functional Foods 2011, 3:229-254.
46. Takemoto Y. Amino acids that centrally influence blood pressure and regional blood flow in conscious rats. Journal of Amino Acids 2012, 2012:1-14. 10.1155/2012/831759.
47. Tavares T., Contreras M., Amorim M., Martín-Álvarez P., Pintado M., Recio I., Malcata F. Optimisation, by response surface methodology, of degree of hydrolysis and antioxidant and ACE-inhibitory activities of whey protein hydrolysates obtained with cardoon extract. International Dairy Journal 2011, 21:926-933.
48. Tavares T., Contreras M., Amorim M., Pintado M., Recio I., Malcata F. Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: In vitro effect and stability to gastrointestinal enzymes. Peptides 2011, 32:1013-1019.
49. Udenigwe C.C., Gong M., Wu S. In silico analysis of the large and small subunits of cereal RuBisCO as precursors of cryptic bioactive peptides. Process Biochemistry 2013, 48:1794-1799.
50. Uluko H., Li H., Cui W., Zhang S., Liu L., Chen J., Sun Y., Su Y., Lv J. Response surface optimization of angiotensin converting enzyme inhibition of milk protein concentrate hydrolysates in vitro after ultrasound pretreatment. Innovative Food Science and Emerging Technologies 2013, 20:133-139.
51. Uluko H., Zhang S., Liu L., Chen J., Sun Y., Su Y., Li H., Cui W., Lv J. Effects of microwave and ultrasound pretreatment on enzymolysis of milk protein concentrate. International Journal of Food Science and Technology 2013, 48:2250-2257.
52. Virtanen T., Pihlanto A., Akkanen S., Korhonen H. Development of antioxidant activity in milk whey during fermentation with lactic acid bacteria. Journal of Applied Microbiology 2007, 102:106-115.
53. Xu J., Zhao Q., Qu Y., Ye F. Free radical scavenging activity of peptide fractions from defatted soybean meal hydrolysates evaluated by electron spin resonance. Food Science and Technology International 2013, 19:557-566.
54. Xu W., Kong B., Zhao X. Optimization of some conditions of Neutrase-catalyzed plastein reaction to mediate ACE-inhibitory activity in vitro of casein hydrolysate prepared by Neutrase. Journal of Food Science and Technology 2014, 51:276-284.
55. Yen G.C., Chen H.Y. Antioxidant activity of various tea extracts in relation to their antimutagenicity. Journal of Agricultural and Food Chemistry 1995, 46:849-854.
56. Zhang Q., Wu H., Ling Y., Lu R. Isolation and identification of antioxidant peptides derived from whey protein enzymatic hydrolysates by consecutive chromatography and Q-TOF MS. Journal of Dairy Research 2013, 80:367-373.