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Volumn 88, Issue 4, 2014, Pages 573-583

Common defects of mitochondria and iron in neurodegeneration and diabetes (MIND): A paradigm worth exploring

Author keywords

Alzheimer's disease; Diabetes; Iron; Mitochondria; Neurodegeneration

Indexed keywords

4 AMINOBUTYRIC ACID; AMYLOID BETA PROTEIN; EXENDIN 4; FERRITIN; FRATAXIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; GLUCOSE; GLUCOSE TRANSPORTER; GLUTAMATE DECARBOXYLASE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; INSULIN; NERVE CELL ADHESION MOLECULE; NEUROTRANSMITTER RECEPTOR; NOTCH RECEPTOR; SODIUM CHANNEL; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; TRANSFERRIN;

EID: 84897954360     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.11.022     Document Type: Review
Times cited : (14)

References (195)
  • 1
    • 80053892506 scopus 로고    scopus 로고
    • Brain aging, Alzheimer's disease, and mitochondria
    • R.H. Swerdlow Brain aging, Alzheimer's disease, and mitochondria Biochim Biophys Acta 1812 12 2011 1630 1639
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.12 , pp. 1630-1639
    • Swerdlow, R.H.1
  • 2
    • 68949158352 scopus 로고    scopus 로고
    • The neurodegenerative mitochondriopathies
    • R.H. Swerdlow The neurodegenerative mitochondriopathies J Alzheimers Dis 17 4 2009 737 751
    • (2009) J Alzheimers Dis , vol.17 , Issue.4 , pp. 737-751
    • Swerdlow, R.H.1
  • 3
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • DOI 10.1126/science.1104343
    • B.B. Lowell, and G.I. Shulman Mitochondrial dysfunction and type 2 diabetes Science 307 5708 2005 384 387 (Pubitemid 40139974)
    • (2005) Science , vol.307 , Issue.5708 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 4
    • 61949188604 scopus 로고    scopus 로고
    • Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications
    • Q. Liu, L. Sun, Y. Tan, G. Wang, X. Lin, and L. Cai Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications Curr Med Chem 16 1 2009 113 129
    • (2009) Curr Med Chem , vol.16 , Issue.1 , pp. 113-129
    • Liu, Q.1    Sun, L.2    Tan, Y.3    Wang, G.4    Lin, X.5    Cai, L.6
  • 8
    • 84882969680 scopus 로고    scopus 로고
    • Cellular pathology of neurodegenerative disorders
    • K. Wakabayashi Cellular pathology of neurodegenerative disorders Rinsho Shinkeigaku 53 8 2013 609 617
    • (2013) Rinsho Shinkeigaku , vol.53 , Issue.8 , pp. 609-617
    • Wakabayashi, K.1
  • 9
    • 84882975956 scopus 로고    scopus 로고
    • Alzheimer's disease: An update
    • J. Sharma Alzheimer's disease: an update Nurs J India 103 6 2012 245 248
    • (2012) Nurs J India , vol.103 , Issue.6 , pp. 245-248
    • Sharma, J.1
  • 10
    • 84877906835 scopus 로고    scopus 로고
    • Tau pathology and neurodegeneration
    • M.G. Spillantini, and M. Goedert Tau pathology and neurodegeneration Lancet Neurol 12 6 2013 609 622
    • (2013) Lancet Neurol , vol.12 , Issue.6 , pp. 609-622
    • Spillantini, M.G.1    Goedert, M.2
  • 11
    • 84898539690 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus in children and adolescents
    • 10.1007/s12098-013-1193-6 [Epub ahead of print]
    • P. Tieh, and D. Dreimane Type 2 diabetes mellitus in children and adolescents Indian J Pediatr 2013 10.1007/s12098-013-1193-6 [Epub ahead of print]
    • (2013) Indian J Pediatr
    • Tieh, P.1    Dreimane, D.2
  • 12
    • 84885738577 scopus 로고    scopus 로고
    • Presence of type 2 diabetes risk factors in children
    • 180
    • L.K. Scott Presence of type 2 diabetes risk factors in children Pediatr Nurs 39 4 2013 190 196 180
    • (2013) Pediatr Nurs , vol.39 , Issue.4 , pp. 190-196
    • Scott, L.K.1
  • 13
    • 84883223305 scopus 로고    scopus 로고
    • Tau pathology in diabetes mellitus
    • J. Wu, S.D. Nie, and S. Wang Tau pathology in diabetes mellitus Pharmazie 68 8 2013 649 652
    • (2013) Pharmazie , vol.68 , Issue.8 , pp. 649-652
    • Wu, J.1    Nie, S.D.2    Wang, S.3
  • 14
    • 84878111480 scopus 로고    scopus 로고
    • Reconsider Alzheimer's disease by the 'calpain-cathepsin hypothesis' - A perspective review
    • T. Yamashima Reconsider Alzheimer's disease by the 'calpain-cathepsin hypothesis' - a perspective review Prog Neurobiol 105 2013 1 23
    • (2013) Prog Neurobiol , vol.105 , pp. 1-23
    • Yamashima, T.1
  • 15
    • 84874587315 scopus 로고    scopus 로고
    • The missing link in the amyloid cascade of Alzheimer's disease - Metal ions
    • A. Tiiman, P. Palumaa, and V. Tougu The missing link in the amyloid cascade of Alzheimer's disease - metal ions Neurochem Int 62 4 2013 367 378
    • (2013) Neurochem Int , vol.62 , Issue.4 , pp. 367-378
    • Tiiman, A.1    Palumaa, P.2    Tougu, V.3
  • 16
    • 84882422403 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
    • H.S. Grover, and S. Luthra Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease J Indian Soc Periodontol 17 3 2013 292 301
    • (2013) J Indian Soc Periodontol , vol.17 , Issue.3 , pp. 292-301
    • Grover, H.S.1    Luthra, S.2
  • 18
    • 3543067962 scopus 로고    scopus 로고
    • Neurodegenetive disorders associated with diabetes mellitus
    • DOI 10.1007/s00109-004-0552-1
    • M. Ristow Neurodegenerative disorders associated with diabetes mellitus J Mol Med (Berl) 82 8 2004 510 529 (Pubitemid 39149861)
    • (2004) Journal of Molecular Medicine , vol.82 , Issue.8 , pp. 510-529
    • Ristow, M.1
  • 19
    • 0842309993 scopus 로고    scopus 로고
    • Increased Risk of Type 2 Diabetes in Alzheimer Disease
    • DOI 10.2337/diabetes.53.2.474
    • J. Janson, T. Laedtke, J.E. Parisi, P. O'Brien, R.C. Petersen, and P.C. Butler Increased risk of type 2 diabetes in Alzheimer disease Diabetes 53 2 2004 474 481 (Pubitemid 38174565)
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 474-481
    • Janson, J.1    Laedtke, T.2    Parisi, J.E.3    O'Brien, P.4    Petersen, R.C.5    Butler, P.C.6
  • 20
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function
    • DOI 10.1001/archneur.61.5.661
    • Z. Arvanitakis, R.S. Wilson, J.L. Bienias, D.A. Evans, and D.A. Bennett Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function Arch Neurol 61 5 2004 661 666 (Pubitemid 38637681)
    • (2004) Archives of Neurology , vol.61 , Issue.5 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 22
    • 79960464624 scopus 로고    scopus 로고
    • Beta-cell evolution: How the pancreas borrowed from the brain
    • M.E. Arntfield, and D. van der Kooy Beta-cell evolution: how the pancreas borrowed from the brain Bioessays 33 8 2011 582 587
    • (2011) Bioessays , vol.33 , Issue.8 , pp. 582-587
    • Arntfield, M.E.1    Van Der Kooy, D.2
  • 23
    • 0015136312 scopus 로고
    • Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas
    • A.G. Pearse, and J.M. Polak Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas Gut 12 10 1971 783 788
    • (1971) Gut , vol.12 , Issue.10 , pp. 783-788
    • Pearse, A.G.1    Polak, J.M.2
  • 25
    • 0033540037 scopus 로고    scopus 로고
    • Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
    • P. Maechler, and C.B. Wollheim Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis Nature 402 6762 1999 685 689 (Pubitemid 129516341)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 685-689
    • Maechler, P.1    Wollheim, C.B.2
  • 26
    • 0025875235 scopus 로고
    • GABA and pancreatic β-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
    • A. Reetz, M. Solimena, M. Matteoli, F. Folli, K. Takei, and P. De Camilli GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion EMBO J 10 5 1991 1275 1284 (Pubitemid 21905590)
    • (1991) EMBO Journal , vol.10 , Issue.5 , pp. 1275-1284
    • Reetz, A.1    Solimena, M.2    Matteoli, M.3    Folli, F.4    Takei, K.5    De Camilli, P.6
  • 28
    • 0021679735 scopus 로고
    • Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells
    • DOI 10.1007/BF01971450
    • J.C. Henquin, and H.P. Meissner Significance of ionic fluxes and changes in membrane-potential for stimulus-secretion coupling in pancreatic B-cells Experientia 40 10 1984 1043 1052 (Pubitemid 15147090)
    • (1984) Experientia , vol.40 , Issue.10 , pp. 1043-1052
    • Henquin, J.C.1    Meissner, H.P.2
  • 29
    • 0032829063 scopus 로고    scopus 로고
    • Hypothalamic glucose sensor: Similarities to and differences from pancreatic β-cell mechanisms
    • DOI 10.2337/diabetes.48.9.1763
    • X.J. Yang, L.M. Kow, T. Funabashi, and C.V. Mobbs Hypothalamic glucose sensor - similarities to and differences from pancreatic beta-cell mechanisms Diabetes 48 9 1999 1763 1772 (Pubitemid 29415195)
    • (1999) Diabetes , vol.48 , Issue.9 , pp. 1763-1772
    • Yang, X.-J.1    Kow, L.-M.2    Funabashi, T.3    Mobbs, C.V.4
  • 31
    • 1842451700 scopus 로고    scopus 로고
    • Brain meets pancreas: Netrin, an axon guidance molecule, controls epithelial cell migration
    • DOI 10.1016/j.tcb.2004.02.005, PII S0962892404000522
    • M. Hebrok, and L.F. Reichardt Brain meets pancreas: netrin, an axon guidance molecule, controls epithelial cell migration Trends Cell Biol 14 4 2004 153 155 (Pubitemid 38447113)
    • (2004) Trends in Cell Biology , vol.14 , Issue.4 , pp. 153-155
    • Hebrok, M.1    Reichardt, L.F.2
  • 33
    • 77952966500 scopus 로고    scopus 로고
    • Derepression of polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program
    • J. van Arensbergen, J. Garcia-Hurtado, I. Moran, M.A. Maestro, X.B. Xu, and M. Van de Casteele et al. Derepression of polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program Genome Res 20 6 2010 722 732
    • (2010) Genome Res , vol.20 , Issue.6 , pp. 722-732
    • Van Arensbergen, J.1    Garcia-Hurtado, J.2    Moran, I.3    Maestro, M.A.4    Xu, X.B.5    Van De Casteele, M.6
  • 34
    • 0027219234 scopus 로고
    • 1-subunit related to a fetal brain isoform
    • L.H. Philipson, A. Kusnetsov, T. Larson, Y.J. Zeng, and G. Westermark Human, rodent, and canine pancreatic beta-cells express a sodium-channel alpha-1-subunit related to a fetal brain isoform Diabetes 42 9 1993 1372 1377 (Pubitemid 23259858)
    • (1993) Diabetes , vol.42 , Issue.9 , pp. 1372-1377
    • Philipson, L.H.1    Kusnetsov, A.2    Larson, T.3    Zeng, Y.4    Westermark, G.5
  • 35
    • 0031019331 scopus 로고    scopus 로고
    • Expression of neuronal traits in pancreatic beta cells: Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer
    • DOI 10.1074/jbc.272.3.1929
    • F. Atouf, P. Czernichow, and R. Scharfmann Expression of neuronal traits in pancreatic beta cells - implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer J Biol Chem 272 3 1997 1929 1934 (Pubitemid 27043287)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.3 , pp. 1929-1934
    • Atouf, F.1    Czernichow, P.2    Scharfmann, R.3
  • 36
    • 77950064307 scopus 로고    scopus 로고
    • Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain
    • S.A. Cruz, Y.C. Tseng, H. Kaiya, and P.P. Hwang Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain Comp Biochem Physiol A Mol Integr Physiol 156 2 2010 190 200
    • (2010) Comp Biochem Physiol A Mol Integr Physiol , vol.156 , Issue.2 , pp. 190-200
    • Cruz, S.A.1    Tseng, Y.C.2    Kaiya, H.3    Hwang, P.P.4
  • 39
    • 0026335927 scopus 로고
    • The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine-cells in the adult-rat
    • S. Thor, J. Ericson, T. Brannstrom, and T. Edlund The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine-cells in the adult-rat Neuron 7 6 1991 881 889
    • (1991) Neuron , vol.7 , Issue.6 , pp. 881-889
    • Thor, S.1    Ericson, J.2    Brannstrom, T.3    Edlund, T.4
  • 40
    • 0348047628 scopus 로고    scopus 로고
    • Gene Regulatory Factors in Pancreatic Development
    • DOI 10.1002/dvdy.10460
    • J. Jensen Gene regulatory factors in pancreatic development Dev Dyn 229 1 2004 176 200 (Pubitemid 38036833)
    • (2004) Developmental Dynamics , vol.229 , Issue.1 , pp. 176-200
    • Jensen, J.1
  • 41
    • 0036471609 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cell fate specification in the developing telencephalon
    • DOI 10.1016/S0959-4388(02)00286-6
    • C. Schuurmans, and F. Guillemot Molecular mechanisms underlying cell fate specification in the developing telencephalon Curr Opin Neurobiol 12 1 2002 26 34 (Pubitemid 34175271)
    • (2002) Current Opinion in Neurobiology , vol.12 , Issue.1 , pp. 26-34
    • Schuurmans, C.1    Guillemot, F.2
  • 42
    • 0348013148 scopus 로고    scopus 로고
    • Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons
    • DOI 10.1242/dev.00815
    • M. Muller, N. Jabs, D.E. Lorke, B. Fritzsch, and M. Sander Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons Development 130 23 2003 5815 5826 (Pubitemid 37540854)
    • (2003) Development , vol.130 , Issue.23 , pp. 5815-5826
    • Muller, M.1    Jabs, N.2    Lorke, D.E.3    Fritzsch, B.4    Sander, M.5
  • 43
    • 0033006664 scopus 로고    scopus 로고
    • The homeodomain transcription factors Islet 1 and HB9 are expressed in adult alpha and gamma motoneurons identified by selective retrograde tracing
    • DOI 10.1046/j.1460-9568.1999.00631.x
    • F. Vult von Steyern, V. Martinov, I. Rabben, A. Nja, O. de Lapeyriere, and T. Lomo The homeodomain transcription factors Islet 1 and HB9 are expressed in adult alpha and gamma motoneurons identified by selective retrograde tracing Eur J Neurosci 11 6 1999 2093 2102 (Pubitemid 29240574)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.6 , pp. 2093-2102
    • Von Vult Steyern, F.1    Martinov, V.2    Rabben, I.3    Nja, A.4    De Lapeyriere, O.5    Lomo, T.6
  • 44
    • 78049445907 scopus 로고    scopus 로고
    • Brain expression of Cre recombinase driven by pancreas-specific promoters
    • J. Song, Y. Xu, X. Hu, B. Choi, and Q. Tong Brain expression of Cre recombinase driven by pancreas-specific promoters Genesis 48 11 2010 628 634
    • (2010) Genesis , vol.48 , Issue.11 , pp. 628-634
    • Song, J.1    Xu, Y.2    Hu, X.3    Choi, B.4    Tong, Q.5
  • 45
    • 0028014432 scopus 로고
    • A role for synaptic vesicles in non-neuronal cells: Clues from pancreatic beta cells and from chromaffin cells
    • A.C. Thomas-Reetz, and P. De Camilli A role for synaptic vesicles in non-neuronal cells: clues from pancreatic beta cells and from chromaffin cells FASEB J 8 2 1994 209 216
    • (1994) FASEB J , vol.8 , Issue.2 , pp. 209-216
    • Thomas-Reetz, A.C.1    De Camilli, P.2
  • 46
    • 0024470349 scopus 로고
    • Glucose-inhibition of glucagon secretion involves activation of GABA(A)-receptor chloride channels
    • DOI 10.1038/341233a0
    • P. Rorsman, P.O. Berggren, K. Bokvist, H. Ericson, H. Mohler, and C.G. Ostenson et al. Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels Nature 341 6239 1989 233 236 (Pubitemid 19231723)
    • (1989) Nature , vol.341 , Issue.6239 , pp. 233-236
    • Rorsman, P.1    Berggren, P.-O.2    Bokvist, K.3    Ericson, H.4    Mohler, H.5    Ostenson, C.-G.6    Smith, P.A.7
  • 47
    • 79960129197 scopus 로고    scopus 로고
    • Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans
    • R. Rodriguez-Diaz, R. Dando, M.C. Jacques-Silva, A. Fachado, J. Molina, and M.H. Abdulreda et al. Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans Nat Med 17 7 2011 888 892
    • (2011) Nat Med , vol.17 , Issue.7 , pp. 888-892
    • Rodriguez-Diaz, R.1    Dando, R.2    Jacques-Silva, M.C.3    Fachado, A.4    Molina, J.5    Abdulreda, M.H.6
  • 49
    • 0030813487 scopus 로고    scopus 로고
    • Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin
    • DOI 10.1038/ng0897-345
    • H. Koutnikova, V. Campuzano, F. Foury, P. Dolle, O. Cazzalini, and M. Koenig Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin Nat Genet 16 4 1997 345 351 (Pubitemid 27323298)
    • (1997) Nature Genetics , vol.16 , Issue.4 , pp. 345-351
    • Koutnikova, H.1    Campuzano, V.2    Foury, F.3    Dolle, P.4    Cazzalini, O.5    Koenig, M.6
  • 51
    • 80455149647 scopus 로고    scopus 로고
    • Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia
    • E. Kim, M. Napierala, and S.Y.R. Dent Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia Nucleic Acids Res 39 19 2011 8366 8377
    • (2011) Nucleic Acids Res , vol.39 , Issue.19 , pp. 8366-8377
    • Kim, E.1    Napierala, M.2    Dent, S.Y.R.3
  • 52
    • 84934444551 scopus 로고    scopus 로고
    • Polyglutamine aggregation in Huntington and related diseases
    • S. Polling, A.F. Hill, and D.M. Hatters Polyglutamine aggregation in Huntington and related diseases Adv Exp Med Biol 769 2012 125 140
    • (2012) Adv Exp Med Biol , vol.769 , pp. 125-140
    • Polling, S.1    Hill, A.F.2    Hatters, D.M.3
  • 53
    • 84934435661 scopus 로고    scopus 로고
    • Molecular pathways to polyglutamine aggregation
    • A.L. Robertson, and S.P. Bottomley Molecular pathways to polyglutamine aggregation Adv Exp Med Biol 769 2012 115 124
    • (2012) Adv Exp Med Biol , vol.769 , pp. 115-124
    • Robertson, A.L.1    Bottomley, S.P.2
  • 54
    • 69949170793 scopus 로고    scopus 로고
    • The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies
    • P.O. Bauer, and N. Nukina The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies J Neurochem 110 6 2009 1737 1765
    • (2009) J Neurochem , vol.110 , Issue.6 , pp. 1737-1765
    • Bauer, P.O.1    Nukina, N.2
  • 55
    • 64049116040 scopus 로고    scopus 로고
    • Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS
    • S. Adinolfi, C. Iannuzzi, F. Prischi, C. Pastore, S. Iametti, and S.R. Martin et al. Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS Nat Struct Mol Biol 16 4 2009 390 396
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.4 , pp. 390-396
    • Adinolfi, S.1    Iannuzzi, C.2    Prischi, F.3    Pastore, C.4    Iametti, S.5    Martin, S.R.6
  • 56
    • 79551514731 scopus 로고    scopus 로고
    • Mammalian frataxin: An essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex
    • S. Schmucker, A. Martelli, F. Colin, A. Page, M. Wattenhofer-Donze, and L. Reutenauer et al. Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex PLoS ONE 6 1 2011
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Schmucker, S.1    Martelli, A.2    Colin, F.3    Page, A.4    Wattenhofer-Donze, M.5    Reutenauer, L.6
  • 57
    • 84880392298 scopus 로고    scopus 로고
    • Animal and cellular models of Friedreich ataxia
    • M. Perdomini, A. Hick, H. Puccio, and M.A. Pook Animal and cellular models of Friedreich ataxia J Neurochem 126 2013 65 79
    • (2013) J Neurochem , vol.126 , pp. 65-79
    • Perdomini, M.1    Hick, A.2    Puccio, H.3    Pook, M.A.4
  • 59
    • 0035138072 scopus 로고    scopus 로고
    • Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
    • DOI 10.1038/84818
    • H. Puccio, D. Simon, M. Cossee, P. Criqui-Filipe, F. Tiziano, and J. Melki et al. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits Nat Genet 27 2 2001 181 186 (Pubitemid 32157445)
    • (2001) Nature Genetics , vol.27 , Issue.2 , pp. 181-186
    • Puccio, H.1    Simon, D.2    Cossee, M.3    Criqui-Filipe, P.4    Tiziano, F.5    Melki, J.6    Hindelang, C.7    Matyas, R.8    Rustin, P.9    Koenig, M.10
  • 60
    • 0242524453 scopus 로고    scopus 로고
    • The Inherited Basis of Diabetes Mellitus: Implications for the Genetic Analysis of Complex Traits
    • DOI 10.1146/annurev.genom.4.070802.110436
    • J.C. Florez, J. Hirschhorn, and D. Altshuler The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits Annu Rev Genomics Hum Genet 4 2003 257 291 (Pubitemid 37392926)
    • (2003) Annual Review of Genomics and Human Genetics , vol.4 , pp. 257-291
    • Florez, J.C.1    Hirschhorn, J.2    Altshuler, D.3
  • 61
    • 0030761094 scopus 로고    scopus 로고
    • The presenilins and Alzheimer's disease
    • DOI 10.1093/hmg/6.10.1639
    • M. Hutton, and J. Hardy The presenilins and Alzheimer's disease Hum Mol Genet 6 10 1997 1639 1646 (Pubitemid 27401606)
    • (1997) Human Molecular Genetics , vol.6 , Issue.10 REV. ISS. , pp. 1639-1646
    • Hutton, M.1    Hardy, J.2
  • 62
    • 0028866435 scopus 로고
    • The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway
    • C. Haass, C.A. Lemere, A. Capell, M. Citron, P. Seubert, and D. Schenk et al. The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway Nat Med 1 12 1995 1291 1296
    • (1995) Nat Med , vol.1 , Issue.12 , pp. 1291-1296
    • Haass, C.1    Lemere, C.A.2    Capell, A.3    Citron, M.4    Seubert, P.5    Schenk, D.6
  • 63
  • 64
    • 80053453887 scopus 로고    scopus 로고
    • Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells
    • W. Wang, Y. Guo, M. Xu, H.H. Huang, L. Novikova, and K. Larade et al. Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells Biochim Biophys Acta 1812 11 2011 1532 1541
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.11 , pp. 1532-1541
    • Wang, W.1    Guo, Y.2    Xu, M.3    Huang, H.H.4    Novikova, L.5    Larade, K.6
  • 66
    • 59149101704 scopus 로고    scopus 로고
    • Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: Riboregulation against neural oxidative damage in Alzheimer's disease
    • J.T. Rogers, A.I. Bush, H.H. Cho, D.H. Smith, A.M. Thomson, and A.L. Friedlich et al. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease Biochem Soc Trans 36 Pt 6 2008 1282 1287
    • (2008) Biochem Soc Trans , vol.36 , Issue.PART 6 , pp. 1282-1287
    • Rogers, J.T.1    Bush, A.I.2    Cho, H.H.3    Smith, D.H.4    Thomson, A.M.5    Friedlich, A.L.6
  • 67
    • 77956647381 scopus 로고    scopus 로고
    • Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimer's disease
    • J.A. Duce, A. Tsatsanis, M.A. Cater, S.A. James, E. Robb, and K. Wikhe et al. Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimer's disease Cell 142 6 2010 857 867
    • (2010) Cell , vol.142 , Issue.6 , pp. 857-867
    • Duce, J.A.1    Tsatsanis, A.2    Cater, M.A.3    James, S.A.4    Robb, E.5    Wikhe, K.6
  • 69
    • 84863683962 scopus 로고    scopus 로고
    • AlphaSynuclein and mitochondrial dysfunction: A pathogenic partnership in Parkinson's disease?
    • D. Protter, C. Lang, and A.A. Cooper alphaSynuclein and mitochondrial dysfunction: a pathogenic partnership in Parkinson's disease? Parkinsons Dis 2012 2012 829207
    • (2012) Parkinsons Dis , vol.2012 , pp. 829207
    • Protter, D.1    Lang, C.2    Cooper, A.A.3
  • 71
    • 0028365102 scopus 로고
    • Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene
    • J.M. van den Ouweland, H.H. Lemkes, R.C. Trembath, R. Ross, G. Velho, and D. Cohen et al. Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene Diabetes 43 6 1994 746 751
    • (1994) Diabetes , vol.43 , Issue.6 , pp. 746-751
    • Van Den Ouweland, J.M.1    Lemkes, H.H.2    Trembath, R.C.3    Ross, R.4    Velho, G.5    Cohen, D.6
  • 72
    • 0034680936 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion
    • H.Y. Wang, P. Maechler, P.A. Antinozzi, K.A. Hagenfeldt, and C.B. Wollheim Hepatocyte nuclear factor 4 alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion J Biol Chem 275 46 2000 35953 35959
    • (2000) J Biol Chem , vol.275 , Issue.46 , pp. 35953-35959
    • Wang, H.Y.1    Maechler, P.2    Antinozzi, P.A.3    Hagenfeldt, K.A.4    Wollheim, C.B.5
  • 73
    • 0034663750 scopus 로고    scopus 로고
    • Molecular targets of a human HNF1α mutation responsible for pancreatic β-cell dysfunction
    • H.Y. Wang, P.A. Antinozzi, K.A. Hagenfeldt, P. Maechler, and C.B. Wollheim Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction EMBO J 19 16 2000 4257 4264 (Pubitemid 30623736)
    • (2000) EMBO Journal , vol.19 , Issue.16 , pp. 4257-4264
    • Wang, H.1    Antinozzi, P.A.2    Hagenfeldt, K.A.3    Maechler, P.4    Wollheim, C.B.5
  • 74
    • 84878974216 scopus 로고    scopus 로고
    • Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice
    • M.A. Brehm, A.C. Powers, L.D. Shultz, and D.L. Greiner Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice Cold Spring Harb Perspect Med 2 5 2012
    • (2012) Cold Spring Harb Perspect Med , vol.2 , Issue.5
    • Brehm, M.A.1    Powers, A.C.2    Shultz, L.D.3    Greiner, D.L.4
  • 75
    • 57649165412 scopus 로고    scopus 로고
    • Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes
    • K. Larade, Z.G. Jiang, Y.Z. Zhang, W.F. Wang, S. Bonner-Weir, and H. Zhu et al. Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes J Biol Chem 283 43 2008 29285 29291
    • (2008) J Biol Chem , vol.283 , Issue.43 , pp. 29285-29291
    • Larade, K.1    Jiang, Z.G.2    Zhang, Y.Z.3    Wang, W.F.4    Bonner-Weir, S.5    Zhu, H.6
  • 76
    • 84878546428 scopus 로고    scopus 로고
    • Natural mutations lead to enhanced proteasomal degradation of human Ncb5or, a novel flavoheme reductase
    • F.S. Kalman, B. Lizak, S.K. Nagy, T. Meszaros, V. Zambo, and J. Mandl et al. Natural mutations lead to enhanced proteasomal degradation of human Ncb5or, a novel flavoheme reductase Biochimie 95 7 2013 1403 1410
    • (2013) Biochimie , vol.95 , Issue.7 , pp. 1403-1410
    • Kalman, F.S.1    Lizak, B.2    Nagy, S.K.3    Meszaros, T.4    Zambo, V.5    Mandl, J.6
  • 77
    • 84897954217 scopus 로고    scopus 로고
    • Impaired iron metabolism in monogenic Ncb5or diabetes
    • [abstract]
    • H. Zhu, W.F. Wang, H.P. Wang, M. Xu, L. E, and R.H. Swerdlow Impaired iron metabolism in monogenic Ncb5or diabetes Diabetes 62 2013 556 587 [abstract]
    • (2013) Diabetes , vol.62 , pp. 556-587
    • Zhu, H.1    Wang, W.F.2    Wang, H.P.3    Xu, M.4    Swerdlow, R.H.5
  • 78
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: Prevalence estimates using the 2000 census
    • DOI 10.1001/archneur.60.8.1119
    • L.E. Hebert, P.A. Scherr, J.L. Bienias, D.A. Bennett, and D.A. Evans Alzheimer disease in the US population - prevalence estimates using the 2000 census Arch Neurol 60 8 2003 1119 1122 (Pubitemid 36975801)
    • (2003) Archives of Neurology , vol.60 , Issue.8 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3    Bennett, D.A.4    Evans, D.A.5
  • 79
    • 84873722367 scopus 로고    scopus 로고
    • Apolipoprotein e and Alzheimer disease: Risk, mechanisms and therapy
    • C.C. Liu, T. Kanekiyo, H. Xu, and G. Bu Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy Nat Rev Neurol 9 2 2013 106 118
    • (2013) Nat Rev Neurol , vol.9 , Issue.2 , pp. 106-118
    • Liu, C.C.1    Kanekiyo, T.2    Xu, H.3    Bu, G.4
  • 82
    • 78650639655 scopus 로고    scopus 로고
    • Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE epsilon 4 allele, the major late-onset Alzheimer's susceptibility gene
    • J. Valla, R. Yaari, A.B. Wolf, Y. Kusne, T.G. Beach, and A.E. Roher et al. Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE epsilon 4 allele, the major late-onset Alzheimer's susceptibility gene J Alzheimers Dis 22 1 2010 307 313
    • (2010) J Alzheimers Dis , vol.22 , Issue.1 , pp. 307-313
    • Valla, J.1    Yaari, R.2    Wolf, A.B.3    Kusne, Y.4    Beach, T.G.5    Roher, A.E.6
  • 83
    • 0028131438 scopus 로고
    • Posterior cingulate cortex in Alzheimer's disease [19]
    • S. Minoshima, N.L. Foster, and D.E. Kuhl Posterior cingulate cortex in Alzheimer's disease Lancet 344 8926 1994 895 (Pubitemid 24290409)
    • (1994) Lancet , vol.344 , Issue.8926 , pp. 895
    • Minoshima, S.1    Foster, N.L.2    Kuhl, D.E.3
  • 85
    • 0035853154 scopus 로고    scopus 로고
    • Declining brain activity in cognitively normal apolipoprotein E ε4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent alzheimer's disease
    • DOI 10.1073/pnas.061509598
    • E.M. Reiman, R.J. Caselli, K. Chen, G.E. Alexander, D. Bandy, and J. Frost Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease Proc Natl Acad Sci USA 98 6 2001 3334 3339 (Pubitemid 32220846)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.6 , pp. 3334-3339
    • Reiman, E.M.1    Caselli, R.J.2    Chen, K.3    Alexander, G.E.4    Bandy, D.5    Frost, J.6
  • 86
    • 0036235195 scopus 로고    scopus 로고
    • Longitudinal PET evaluation of cerebral metabolic decline in dementia: A potential outcome measure in Alzheimer's disease treatment studies
    • DOI 10.1176/appi.ajp.159.5.738
    • G.E. Alexander, K. Chen, P. Pietrini, S.I. Rapoport, and E.M. Reiman Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies Am J Psychiatry 159 5 2002 738 745 (Pubitemid 34465046)
    • (2002) American Journal of Psychiatry , vol.159 , Issue.5 , pp. 738-745
    • Alexander, G.E.1    Chen, K.2    Pietrini, P.3    Rapoport, S.I.4    Reiman, E.M.5
  • 87
    • 0035399655 scopus 로고    scopus 로고
    • Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: Superficial laminar cytochrome oxidase associated with disease duration
    • J. Valla, J.D. Berndt, and F. Gonzalez-Lima Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration J Neurosci 21 13 2001 4923 4930 (Pubitemid 32565651)
    • (2001) Journal of Neuroscience , vol.21 , Issue.13 , pp. 4923-4930
    • Valla, J.1    Berndt, J.D.2    Gonzalez-Lima, F.3
  • 89
    • 54149085713 scopus 로고    scopus 로고
    • Decreased cognition in children with risk factors for Alzheimer's disease
    • C.S. Bloss, D.C. Delis, D.P. Salmon, and M.W. Bondi Decreased cognition in children with risk factors for Alzheimer's disease Biol Psychiatry 64 10 2008 904 906
    • (2008) Biol Psychiatry , vol.64 , Issue.10 , pp. 904-906
    • Bloss, C.S.1    Delis, D.C.2    Salmon, D.P.3    Bondi, M.W.4
  • 90
    • 84899637954 scopus 로고    scopus 로고
    • Multiple sclerosis: Basic knowledge and new insights in perioperative management
    • 10.1007/s00540-013-1697-2 [Epub ahead of print]
    • A. Makris, A. Piperopoulos, and I. Karmaniolou Multiple sclerosis: basic knowledge and new insights in perioperative management J Anesth 2013 10.1007/s00540-013-1697-2 [Epub ahead of print]
    • (2013) J Anesth
    • Makris, A.1    Piperopoulos, A.2    Karmaniolou, I.3
  • 91
    • 1842608738 scopus 로고    scopus 로고
    • Hereditary causes of disturbed iron homeostasis in the central nervous system
    • DOI 10.1196/annals.1306.022
    • P. Ponka Hereditary causes of disturbed iron homeostasis in the central nervous system Ann N Y Acad Sci 1012 2004 267 281 (Pubitemid 38453531)
    • (2004) Annals of the New York Academy of Sciences , vol.1012 , pp. 267-281
    • Ponka, P.1
  • 92
    • 83255181779 scopus 로고    scopus 로고
    • Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11 C]Pittsburgh compound B data
    • A.G. Vlassenko, M.A. Mintun, C.J. Xiong, Y.I. Sheline, A.M. Goate, and T.L.S. Benzinger et al. Amyloid-beta plaque growth in cognitively normal adults: longitudinal [11 C]Pittsburgh compound B data Ann Neurol 70 5 2011 857 861
    • (2011) Ann Neurol , vol.70 , Issue.5 , pp. 857-861
    • Vlassenko, A.G.1    Mintun, M.A.2    Xiong, C.J.3    Sheline, Y.I.4    Goate, A.M.5    Benzinger, T.L.S.6
  • 93
    • 60349125886 scopus 로고    scopus 로고
    • Reassessing the amyloid cascade hypothesis of Alzheimer's disease
    • S.W. Pimplikar Reassessing the amyloid cascade hypothesis of Alzheimer's disease Int J Biochem Cell Biol 41 6 2009 1261 1268
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.6 , pp. 1261-1268
    • Pimplikar, S.W.1
  • 96
    • 3042806534 scopus 로고    scopus 로고
    • A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease
    • DOI 10.1016/j.mehy.2003.12.045, PII S0306987704001252
    • R.H. Swerdlow, and S.M. Khan A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease Med Hypotheses 63 1 2004 8 20 (Pubitemid 38887104)
    • (2004) Medical Hypotheses , vol.63 , Issue.1 , pp. 8-20
    • Swerdlow, R.H.1    Khan, S.M.2
  • 97
    • 67649687124 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis: An update
    • R.H. Swerdlow, and S.M. Khan The Alzheimer's disease mitochondrial cascade hypothesis: an update Exp Neurol 218 2 2009 308 315
    • (2009) Exp Neurol , vol.218 , Issue.2 , pp. 308-315
    • Swerdlow, R.H.1    Khan, S.M.2
  • 98
    • 77956224679 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis
    • R.H. Swerdlow, J.M. Burns, and S.M. Khan The Alzheimer's disease mitochondrial cascade hypothesis J Alzheimers Dis 20 Suppl. 2 2010 S265 S279
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 2
    • Swerdlow, R.H.1    Burns, J.M.2    Khan, S.M.3
  • 99
    • 84903304968 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
    • 10.1016/j.bbadis.2013.09.010 pii: S0925-4439(13)00289-5 [Epub ahead of print]
    • R.H. Swerdlow, J.M. Burns, and S.M. Khan The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives Biochim Biophys Acta 2013 10.1016/j.bbadis.2013.09.010 pii: S0925-4439(13)00289-5 [Epub ahead of print]
    • (2013) Biochim Biophys Acta
    • Swerdlow, R.H.1    Burns, J.M.2    Khan, S.M.3
  • 100
    • 0018826694 scopus 로고
    • Coenzyme A-acetylating enzymes in Alzheimer's disease: Possible cholinergic 'compartment' of pyruvate dehydrogenase
    • DOI 10.1016/0304-3940(80)90220-7
    • E.K. Perry, R.H. Perry, B.E. Tomlinson, G. Blessed, and P.H. Gibson Coenzyme A-acetylating enzymes in Alzheimer's disease: possible cholinergic 'compartment' of pyruvate dehydrogenase Neurosci Lett 18 1 1980 105 110 (Pubitemid 10122792)
    • (1980) Neuroscience Letters , vol.18 , Issue.1 , pp. 105-110
    • Perry, E.K.1    Perry, R.H.2    Tomlinson, B.E.3
  • 101
    • 0020685951 scopus 로고
    • Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain
    • DOI 10.1002/ana.410130116
    • S. Sorbi, E.D. Bird, and J.P. Blass Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain Ann Neurol 13 1 1983 72 78 (Pubitemid 13224203)
    • (1983) Annals of Neurology , vol.13 , Issue.1 , pp. 72-78
    • Sorbi, S.1    Bird, E.D.2    Blass, J.P.3
  • 102
    • 0023732664 scopus 로고
    • Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease
    • G.E. Gibson, K.F. Sheu, J.P. Blass, A. Baker, K.C. Carlson, and B. Harding et al. Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease Arch Neurol 45 8 1988 836 840
    • (1988) Arch Neurol , vol.45 , Issue.8 , pp. 836-840
    • Gibson, G.E.1    Sheu, K.F.2    Blass, J.P.3    Baker, A.4    Carlson, K.C.5    Harding, B.6
  • 104
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • K. Talbot, H.Y. Wang, H. Kazi, L.Y. Han, K.P. Bakshi, and A. Stucky et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline J Clin Invest 122 4 2012 1316 1338
    • (2012) J Clin Invest , vol.122 , Issue.4 , pp. 1316-1338
    • Talbot, K.1    Wang, H.Y.2    Kazi, H.3    Han, L.Y.4    Bakshi, K.P.5    Stucky, A.6
  • 105
    • 0025024024 scopus 로고
    • Cytochrome oxidase deficiency in Alzheimer's disease
    • W.D. Parker Jr., C.M. Filley, and J.K. Parks Cytochrome oxidase deficiency in Alzheimer's disease Neurology 40 8 1990 1302 1303 (Pubitemid 20244999)
    • (1990) Neurology , vol.40 , Issue.8 , pp. 1302-1303
    • Parker Jr., W.D.1    Filley, C.M.2    Parks, J.K.3
  • 107
    • 0028110234 scopus 로고
    • Cortical cytochrome oxidase activity is reduced in Alzheimer's disease
    • E.M. Mutisya, A.C. Bowling, and M.F. Beal Cortical cytochrome-oxidase activity is reduced in Alzheimers-disease J Neurochem 63 6 1994 2179 2184 (Pubitemid 24369993)
    • (1994) Journal of Neurochemistry , vol.63 , Issue.6 , pp. 2179-2184
    • Mutisya, E.M.1    Bowling, A.C.2    Beal, M.F.3
  • 108
    • 0030930721 scopus 로고    scopus 로고
    • Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells
    • DOI 10.1016/S0304-3940(97)00536-3, PII S0304394097005363
    • L. Gasparini, M. Racchi, L. Benussi, D. Curti, G. Binetti, and A. Bianchetti et al. Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells Neurosci Lett 231 2 1997 113 117 (Pubitemid 27386502)
    • (1997) Neuroscience Letters , vol.231 , Issue.2 , pp. 113-117
    • Gasparini, L.1    Racchi, M.2    Benussi, L.3    Curti, D.4    Binetti, G.5    Bianchetti, A.6    Trabucchi, M.7    Govoni, S.8
  • 109
    • 0028200649 scopus 로고
    • Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
    • D. Gabuzda, J. Busciglio, L.B. Chen, P. Matsudaira, and B.A. Yankner Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative J Biol Chem 269 18 1994 13623 13628 (Pubitemid 24206141)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.18 , pp. 13623-13628
    • Gabuzda, D.1    Busciglio, J.2    Chen, L.B.3    Matsudaira, P.4    Yankner, B.A.5
  • 111
    • 34347353834 scopus 로고    scopus 로고
    • Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies
    • DOI 10.1002/jnr.21167
    • R.H. Swerdlow Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies J Neurosci Res 85 15 2007 3416 3428 (Pubitemid 350058530)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.15 , pp. 3416-3428
    • Swerdlow, R.H.1
  • 112
    • 84885187866 scopus 로고    scopus 로고
    • Pathophysiology and treatment of neurodegeneration with brain iron accumulation in the pediatric population
    • S.A. Schneider, G. Zorzi, and N. Nardocci Pathophysiology and treatment of neurodegeneration with brain iron accumulation in the pediatric population Curr Treat Options Neurol 15 5 2013 652 667
    • (2013) Curr Treat Options Neurol , vol.15 , Issue.5 , pp. 652-667
    • Schneider, S.A.1    Zorzi, G.2    Nardocci, N.3
  • 113
    • 84873440661 scopus 로고    scopus 로고
    • Effect of conjugated linoleic acid, mu-calpain inhibitor, on pathogenesis of Alzheimer's disease
    • E. Lee, J.E. Eom, H.L. Kim, K.H. Baek, K.Y. Jun, and H.J. Kim et al. Effect of conjugated linoleic acid, mu-calpain inhibitor, on pathogenesis of Alzheimer's disease Biochim Biophys Acta-Mol Cell Biol Lipids 1831 4 2013 709 718
    • (2013) Biochim Biophys Acta-Mol Cell Biol Lipids , vol.1831 , Issue.4 , pp. 709-718
    • Lee, E.1    Eom, J.E.2    Kim, H.L.3    Baek, K.H.4    Jun, K.Y.5    Kim, H.J.6
  • 114
    • 84875254177 scopus 로고    scopus 로고
    • Beta amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice
    • C.A. Briggs, C. Schneider, J.C. Richardson, and G.E. Stutzmann Beta amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice Neurobiol Aging 34 6 2013 1632 1643
    • (2013) Neurobiol Aging , vol.34 , Issue.6 , pp. 1632-1643
    • Briggs, C.A.1    Schneider, C.2    Richardson, J.C.3    Stutzmann, G.E.4
  • 115
    • 0032526940 scopus 로고    scopus 로고
    • The regulation of reactive oxygen species production during programmed cell death
    • DOI 10.1083/jcb.141.6.1423
    • S. Tan, Y. Sagara, Y. Liu, P. Maher, and D. Schubert The regulation of reactive oxygen species production during programmed cell death J Cell Biol 141 6 1998 1423 1432 (Pubitemid 28289917)
    • (1998) Journal of Cell Biology , vol.141 , Issue.6 , pp. 1423-1432
    • Tan, S.1    Sagara, Y.2    Liu, Y.3    Maher, P.4    Schubert, D.5
  • 116
    • 33745628757 scopus 로고    scopus 로고
    • Generation of superoxide by the mitochondrial Complex I
    • DOI 10.1016/j.bbabio.2006.03.013, PII S0005272806000685
    • V.G. Grivennikova, and A.D. Vinogradov Generation of superoxide by the mitochondrial complex I Biochim Biophys Acta 1757 5-6 2006 553 561 (Pubitemid 43993849)
    • (2006) Biochimica et Biophysica Acta - Bioenergetics , vol.1757 , Issue.5-6 , pp. 553-561
    • Grivennikova, V.G.1    Vinogradov, A.D.2
  • 117
    • 75949121583 scopus 로고    scopus 로고
    • Oxidative stress in the progression of Alzheimer disease in the frontal cortex
    • M.A. Ansari, and S.W. Scheff Oxidative stress in the progression of Alzheimer disease in the frontal cortex J Neuropathol Exp Neurol 69 2 2010 155 167
    • (2010) J Neuropathol Exp Neurol , vol.69 , Issue.2 , pp. 155-167
    • Ansari, M.A.1    Scheff, S.W.2
  • 118
    • 84879430920 scopus 로고    scopus 로고
    • Sites of reactive oxygen species generation by mitochondria oxidizing different substrates
    • C.L. Quinlan, I.V. Perevoshchikova, M. Hey-Mogensen, A.L. Orr, and M.D. Brand Sites of reactive oxygen species generation by mitochondria oxidizing different substrates Redox Biol 1 1 2013 304 312
    • (2013) Redox Biol , vol.1 , Issue.1 , pp. 304-312
    • Quinlan, C.L.1    Perevoshchikova, I.V.2    Hey-Mogensen, M.3    Orr, A.L.4    Brand, M.D.5
  • 119
    • 0030016323 scopus 로고    scopus 로고
    • Increased risk of dementia in mothers of Alzheimer's disease cases: Evidence for maternal inheritance
    • S.D. Edland, J.M. Silverman, E.R. Peskind, D. Tsuang, E. Wijsman, and J.C. Morris Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal inheritance Neurology 47 1 1996 254 256 (Pubitemid 26243893)
    • (1996) Neurology , vol.47 , Issue.1 , pp. 254-256
    • Edland, S.D.1    Silverman, J.M.2    Peskind, E.R.3    Tsuang, D.4    Wijsman, E.5    Morris, J.C.6
  • 120
    • 85027951376 scopus 로고    scopus 로고
    • Maternal transmission of Alzheimer's disease: Prodromal metabolic phenotype and the search for genes
    • L. Mosconi, V. Berti, R.H. Swerdlow, A. Pupi, R. Duara, and M. de Leon Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes Hum Genomics 4 3 2010 170 193
    • (2010) Hum Genomics , vol.4 , Issue.3 , pp. 170-193
    • Mosconi, L.1    Berti, V.2    Swerdlow, R.H.3    Pupi, A.4    Duara, R.5    De Leon, M.6
  • 124
    • 0032613038 scopus 로고    scopus 로고
    • Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease
    • C.S. Atwood, X.D. Huang, R.D. Moir, R.E. Tanzi, and A.I. Bush Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease Met Ions Biol Syst 36 1999 309 364
    • (1999) Met Ions Biol Syst , vol.36 , pp. 309-364
    • Atwood, C.S.1    Huang, X.D.2    Moir, R.D.3    Tanzi, R.E.4    Bush, A.I.5
  • 126
    • 84938039523 scopus 로고
    • Alzheimer's disease; A clinico-pathologic analysis of twenty-three cases with a theory on pathogenesis
    • L. Goodman Alzheimer's disease; a clinico-pathologic analysis of twenty-three cases with a theory on pathogenesis J Nerv Ment Dis 118 2 1953 97 130
    • (1953) J Nerv Ment Dis , vol.118 , Issue.2 , pp. 97-130
    • Goodman, L.1
  • 129
    • 0036724204 scopus 로고    scopus 로고
    • Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: Implications in the formation of neurofibrillary tangles of Alzheimer's disease
    • DOI 10.1046/j.1471-4159.2002.01061.x
    • A. Yamamoto, R.W. Shin, K. Hasegawa, H. Naiki, H. Sato, and F. Yoshimasu et al. Iron(III) induces aggregation of hyperphosphorylated tau and its reduction to iron(II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease J Neurochem 82 5 2002 1137 1147 (Pubitemid 34966626)
    • (2002) Journal of Neurochemistry , vol.82 , Issue.5 , pp. 1137-1147
    • Yamamoto, A.1    Shin, R.-W.2    Hasegawa, K.3    Naiki, H.4    Sato, H.5    Yoshimasu, F.6    Kitamoto, T.7
  • 130
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid β protein toxicity
    • DOI 10.1016/0092-8674(94)90131-7
    • C. Behl, J.B. Davis, R. Lesley, and D. Schubert Hydrogen-peroxide mediates amyloid-beta protein toxicity Cell 77 6 1994 817 827 (Pubitemid 24187680)
    • (1994) Cell , vol.77 , Issue.6 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 132
    • 0028908516 scopus 로고
    • Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons
    • M.E. Harris, K. Hensley, D.A. Butterfield, R.A. Leedle, and J.M. Carney Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons Exp Neurol 131 2 1995 193 202
    • (1995) Exp Neurol , vol.131 , Issue.2 , pp. 193-202
    • Harris, M.E.1    Hensley, K.2    Butterfield, D.A.3    Leedle, R.A.4    Carney, J.M.5
  • 133
    • 84857658656 scopus 로고    scopus 로고
    • Iron enhances the neurotoxicity of amyloid beta
    • L. Wang, G. Xi, R.F. Keep, and Y. Hua Iron enhances the neurotoxicity of amyloid beta Transl Stroke Res 3 1 2012 107 113
    • (2012) Transl Stroke Res , vol.3 , Issue.1 , pp. 107-113
    • Wang, L.1    Xi, G.2    Keep, R.F.3    Hua, Y.4
  • 134
    • 84859390312 scopus 로고    scopus 로고
    • Altered serum iron and copper homeostasis predicts cognitive decline in mild cognitive impairment
    • C. Mueller, M. Schrag, A. Crofton, J. Stolte, M.U. Muckenthaler, and S. Magaki et al. Altered serum iron and copper homeostasis predicts cognitive decline in mild cognitive impairment J Alzheimers Dis 29 2 2012 341 350
    • (2012) J Alzheimers Dis , vol.29 , Issue.2 , pp. 341-350
    • Mueller, C.1    Schrag, M.2    Crofton, A.3    Stolte, J.4    Muckenthaler, M.U.5    Magaki, S.6
  • 135
    • 0030974795 scopus 로고    scopus 로고
    • Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains
    • DOI 10.1016/S0387-7604(97)00559-7, PII S0387760497005597
    • Y. Arai, A. Suzuki, M. Mizuguchi, and S. Takashima Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains Brain Dev 19 4 1997 290 294 (Pubitemid 27236856)
    • (1997) Brain and Development , vol.19 , Issue.4 , pp. 290-294
    • Arai, Y.1    Suzuki, A.2    Mizuguchi, M.3    Takashima, S.4
  • 136
    • 34948858043 scopus 로고    scopus 로고
    • Heme as a magnificient molecule with multiple missions: Heme determines its own fate and governs cellular homeostasis
    • DOI 10.1620/tjem.213.1
    • K. Furuyama, K. Kaneko, and P.D. Vargas Heme as a magnificent molecule with multiple missions: Heme determines its own fate and governs cellular homeostasis Tohoku J Exp Med 213 1 2007 1 16 (Pubitemid 47516896)
    • (2007) Tohoku Journal of Experimental Medicine , vol.213 , Issue.1 , pp. 1-16
    • Furuyama, K.1    Kaneko, K.2    Vargas, P.D.3
  • 137
    • 77956218282 scopus 로고    scopus 로고
    • Mitochondrial iron metabolism and its role in neurodegeneration
    • M.P. Horowitz, and J.T. Greenamyre Mitochondrial iron metabolism and its role in neurodegeneration J Alzheimers Dis 20 2010 S551 S568
    • (2010) J Alzheimers Dis , vol.20
    • Horowitz, M.P.1    Greenamyre, J.T.2
  • 138
    • 0031574362 scopus 로고    scopus 로고
    • Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging
    • DOI 10.1016/S0169-328X(97)00278-7, PII S0169328X97002787
    • A. Barrientos, J. Casademont, F. Cardellach, X. Estivill, A. Urbano-Marquez, and V. Nunes Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging Brain Res Mol Brain Res 52 2 1997 284 289 (Pubitemid 28043472)
    • (1997) Molecular Brain Research , vol.52 , Issue.2 , pp. 284-289
    • Barrientos, A.1    Casademont, J.2    Cardellach, F.3    Estivill, X.4    Urbano-Marquez, A.5    Nunes, V.6
  • 139
    • 0027017232 scopus 로고
    • Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
    • M. Corral-Debrinski, T. Horton, M.T. Lott, J.M. Shoffner, M.F. Beal, and D.C. Wallace Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age Nat Genet 2 4 1992 324 329
    • (1992) Nat Genet , vol.2 , Issue.4 , pp. 324-329
    • Corral-Debrinski, M.1    Horton, T.2    Lott, M.T.3    Shoffner, J.M.4    Beal, M.F.5    Wallace, D.C.6
  • 140
    • 0036982389 scopus 로고    scopus 로고
    • Mitochondria in Alzheimer's disease
    • R.H. Swerdlow, and S.J. Kish Mitochondria in Alzheimer's disease Int Rev Neurobiol 53 2002 341 385
    • (2002) Int Rev Neurobiol , vol.53 , pp. 341-385
    • Swerdlow, R.H.1    Kish, S.J.2
  • 141
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • DOI 10.1038/414799a
    • A.R. Saltiel, and C.R. Kahn Insulin signalling and the regulation of glucose and lipid metabolism Nature 414 6865 2001 799 806 (Pubitemid 34000783)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 143
    • 84884535368 scopus 로고    scopus 로고
    • Mitochondrial function and insulin secretion
    • P. Maechler Mitochondrial function and insulin secretion Mol Cell Endocrinol 379 1-2 2013 12 18
    • (2013) Mol Cell Endocrinol , vol.379 , Issue.12 , pp. 12-18
    • Maechler, P.1
  • 144
    • 84875652238 scopus 로고    scopus 로고
    • Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E
    • B.S. Jhun, H. Lee, Z.G. Jin, and Y. Yoon Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E PLoS ONE 8 4 2013 e60810
    • (2013) PLoS ONE , vol.8 , Issue.4 , pp. 60810
    • Jhun, B.S.1    Lee, H.2    Jin, Z.G.3    Yoon, Y.4
  • 145
    • 33947592820 scopus 로고    scopus 로고
    • Mitochondrial GTP Regulates Glucose-Stimulated Insulin Secretion
    • DOI 10.1016/j.cmet.2007.02.008, PII S155041310700040X
    • R.G. Kibbey, R.L. Pongratz, A.J. Romanelli, C.B. Wollheim, G.W. Cline, and G.I. Shulman Mitochondrial GTP regulates glucose-stimulated insulin secretion Cell Metab 5 4 2007 253 264 (Pubitemid 46477853)
    • (2007) Cell Metabolism , vol.5 , Issue.4 , pp. 253-264
    • Kibbey, R.G.1    Pongratz, R.L.2    Romanelli, A.J.3    Wollheim, C.B.4    Cline, G.W.5    Shulman, G.I.6
  • 146
    • 0036217052 scopus 로고    scopus 로고
    • Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
    • DOI 10.1210/er.23.2.201
    • G.F. Lewis, A. Carpentier, K. Adeli, and A. Giacca Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes Endocr Rev 23 2 2002 201 229 (Pubitemid 34299024)
    • (2002) Endocrine Reviews , vol.23 , Issue.2 , pp. 201-229
    • Lewis, G.F.1    Carpentier, A.2    Adeli, K.3    Giacca, A.4
  • 147
    • 84895555916 scopus 로고    scopus 로고
    • The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes
    • 10.1016/j.bbagen.2013.09.019 pii: S0304-4165(13)00400-5
    • S.D. Martin, and S.L. McGee The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes Biochim Biophys Acta 2013 10.1016/j.bbagen.2013.09.019 pii: S0304-4165(13)00400-5
    • (2013) Biochim Biophys Acta
    • Martin, S.D.1    McGee, S.L.2
  • 148
    • 0024995157 scopus 로고
    • A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation
    • Y. Sako, and V.E. Grill A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin-secretion and B-cell oxidation through a process likely coupled to fatty-acid oxidation Endocrinology 127 4 1990 1580 1589 (Pubitemid 20315212)
    • (1990) Endocrinology , vol.127 , Issue.4 , pp. 1580-1589
    • Sako, Y.1    Grill, V.E.2
  • 149
    • 85025386842 scopus 로고
    • The relation Oe diabetes mellitus to lesions of the pancreas. Hyaline degeneration of the islands Oe Langerhans
    • E.L. Opie The relation Oe diabetes mellitus to lesions of the pancreas. Hyaline degeneration of the islands Oe Langerhans J Exp Med 5 5 1901 527 540
    • (1901) J Exp Med , vol.5 , Issue.5 , pp. 527-540
    • Opie, E.L.1
  • 150
    • 0023025399 scopus 로고
    • A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas
    • DOI 10.1016/0006-291X(86)90708-4
    • P. Westermark, C. Wernstedt, E. Wilander, and K. Sletten A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas Biochem Biophys Res Commun 140 3 1986 827 831 (Pubitemid 17207764)
    • (1986) Biochemical and Biophysical Research Communications , vol.140 , Issue.3 , pp. 827-831
    • Westermark, P.1    Wernstedt, C.2    Wilander, E.3    Sletten, K.4
  • 152
    • 84907135505 scopus 로고
    • Amyloid and polypeptide hormones - What is their interrelationship
    • P. Westermark Amyloid and polypeptide hormones - what is their interrelationship Amyloid 1 1 1994 47 60
    • (1994) Amyloid , vol.1 , Issue.1 , pp. 47-60
    • Westermark, P.1
  • 153
    • 79952101635 scopus 로고    scopus 로고
    • Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin
    • X.L. Li, T. Chen, Y.S. Wong, G. Xu, R.R. Fan, and H.L. Zhao et al. Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: an effect attenuated by phycocyanin Int J Biochem Cell Biol 43 4 2011 525 534
    • (2011) Int J Biochem Cell Biol , vol.43 , Issue.4 , pp. 525-534
    • Li, X.L.1    Chen, T.2    Wong, Y.S.3    Xu, G.4    Fan, R.R.5    Zhao, H.L.6
  • 154
    • 84892690389 scopus 로고    scopus 로고
    • The neuroprotection of liraglutide on Alzheimer-like learning and memory impairment by modulating the hyperphosphorylation of tau and neurofilament proteins and insulin signaling pathways in mice
    • H. Xiong, C. Zheng, J. Wang, J. Song, G. Zhao, and H. Shen et al. The neuroprotection of liraglutide on Alzheimer-like learning and memory impairment by modulating the hyperphosphorylation of tau and neurofilament proteins and insulin signaling pathways in mice J Alzheimers Dis 37 3 2013 623 635
    • (2013) J Alzheimers Dis , vol.37 , Issue.3 , pp. 623-635
    • Xiong, H.1    Zheng, C.2    Wang, J.3    Song, J.4    Zhao, G.5    Shen, H.6
  • 155
    • 84897848470 scopus 로고    scopus 로고
    • Central effects of GLP-1: New opportunities for treatments of neurodegenerative diseases
    • 10.1530/JOE-13-0221 [Epub ahead of print]
    • C. Holscher Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases J Endocrinol 2013 10.1530/JOE-13-0221 [Epub ahead of print]
    • (2013) J Endocrinol
    • Holscher, C.1
  • 156
    • 77955019118 scopus 로고    scopus 로고
    • Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: Potential involvement of AKT and mitochondria biogenesis
    • R. Fan, X. Li, X. Gu, J.C. Chan, and G. Xu Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis Diabetes Obes Metab 12 9 2010 815 824
    • (2010) Diabetes Obes Metab , vol.12 , Issue.9 , pp. 815-824
    • Fan, R.1    Li, X.2    Gu, X.3    Chan, J.C.4    Xu, G.5
  • 157
    • 84861460226 scopus 로고    scopus 로고
    • Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy
    • M. Kan, G. Guo, B. Singh, V. Singh, and D.W. Zochodne Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy J Neuropathol Exp Neurol 71 6 2012 494 510
    • (2012) J Neuropathol Exp Neurol , vol.71 , Issue.6 , pp. 494-510
    • Kan, M.1    Guo, G.2    Singh, B.3    Singh, V.4    Zochodne, D.W.5
  • 158
  • 160
    • 3142758093 scopus 로고    scopus 로고
    • Elevated iron indices in patients with diabetes
    • DOI 10.1111/j.1464-5491.2004.01196.x
    • M.C. Thomas, R.J. MacIsaac, C. Tsalamandris, and G. Jerums Elevated iron indices in patients with diabetes Diabet Med 21 7 2004 798 802 (Pubitemid 38916230)
    • (2004) Diabetic Medicine , vol.21 , Issue.7 , pp. 798-802
    • Thomas, M.C.1    Maclsaac, R.J.2    Tsalamandrist, C.3    Jerums, G.4
  • 161
    • 0033364044 scopus 로고    scopus 로고
    • Diabetes and serum ferritin concentration among U.S. Adults
    • E.S. Ford, and M.E. Cogswell Diabetes and serum ferritin concentration among US adults Diabetes Care 22 12 1999 1978 1983 (Pubitemid 30433975)
    • (1999) Diabetes Care , vol.22 , Issue.12 , pp. 1978-1983
    • Ford, E.S.1    Cogswell, M.E.2
  • 163
    • 84887627392 scopus 로고    scopus 로고
    • High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. Adults
    • C.L. Cheung, T.T. Cheung, K.S. Lam, and B.M. Cheung High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults Clin Nutr 32 6 2013 1055 1060
    • (2013) Clin Nutr , vol.32 , Issue.6 , pp. 1055-1060
    • Cheung, C.L.1    Cheung, T.T.2    Lam, K.S.3    Cheung, B.M.4
  • 164
    • 84871680844 scopus 로고    scopus 로고
    • Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: A meta-analysis
    • Y. Rong, W. Bao, S. Rong, M. Fang, D. Wang, and P. Yao et al. Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: a meta-analysis Am J Epidemiol 176 6 2012 461 472
    • (2012) Am J Epidemiol , vol.176 , Issue.6 , pp. 461-472
    • Rong, Y.1    Bao, W.2    Rong, S.3    Fang, M.4    Wang, D.5    Yao, P.6
  • 165
    • 14744290384 scopus 로고    scopus 로고
    • Dietary iron intake and blood donations in relation to risk of type 2 diabetes in men: A prospective cohort study
    • R. Jiang, J. Ma, A. Ascherio, M.J. Stampfer, W.C. Willett, and F.B. Hu Dietary iron intake and blood donations in relation to risk of type 2 diabetes in men: a prospective cohort study Am J Clin Nutr 79 1 2004 70 75 (Pubitemid 41132064)
    • (2004) American Journal of Clinical Nutrition , vol.79 , Issue.1 , pp. 70-75
    • Jiang, R.1    Ma, J.2    Ascherio, A.3    Stampfer, M.J.4    Willett, W.C.5    Hu, F.B.6
  • 166
    • 23444453550 scopus 로고    scopus 로고
    • Iron stores, blood donation, and insulin sensitivity and secretion
    • DOI 10.1373/clinchem.2004.046847
    • J.M. Fernandez-Real, A. Lopez-Bermejo, and W. Ricart Iron stores, blood donation, and insulin sensitivity and secretion Clin Chem 51 7 2005 1201 1205 (Pubitemid 43079398)
    • (2005) Clinical Chemistry , vol.51 , Issue.7 , pp. 1201-1205
    • Fernandez-Real, J.M.1    Lopez-Bermejo, A.2    Ricart, W.3
  • 168
    • 84872685206 scopus 로고    scopus 로고
    • The role of aberrant mitochondrial bioenergetics in diabetic neuropathy
    • S.K. Chowdhury, D.R. Smith, and P. Fernyhough The role of aberrant mitochondrial bioenergetics in diabetic neuropathy Neurobiol Dis 51 2013 56 65
    • (2013) Neurobiol Dis , vol.51 , pp. 56-65
    • Chowdhury, S.K.1    Smith, D.R.2    Fernyhough, P.3
  • 169
    • 82755197943 scopus 로고    scopus 로고
    • Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes
    • S.K. Chowdhury, R.T. Dobrowsky, and P. Fernyhough Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes Mitochondrion 11 6 2011 845 854
    • (2011) Mitochondrion , vol.11 , Issue.6 , pp. 845-854
    • Chowdhury, S.K.1    Dobrowsky, R.T.2    Fernyhough, P.3
  • 170
    • 84870910517 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor activates NF-kappa B to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin- induced diabetic rodents
    • A. Saleh, S.K.R. Chowdhury, D.R. Smith, S. Balakrishnan, L. Tessler, and C. Martens et al. Ciliary neurotrophic factor activates NF-kappa B to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents Neuropharmacology 65 2013 65 73
    • (2013) Neuropharmacology , vol.65 , pp. 65-73
    • Saleh, A.1    Chowdhury, S.K.R.2    Smith, D.R.3    Balakrishnan, S.4    Tessler, L.5    Martens, C.6
  • 171
    • 0035135246 scopus 로고    scopus 로고
    • Advanced glycation end-products: A review
    • DOI 10.1007/s001250051591
    • R. Singh, A. Barden, T. Mori, and L. Beilin Advanced glycation end-products: a review Diabetologia 44 2 2001 129 146 (Pubitemid 32156196)
    • (2001) Diabetologia , vol.44 , Issue.2 , pp. 129-146
    • Singh, R.1    Barden, A.2    Mori, T.3    Beilin, L.4
  • 172
    • 84888108332 scopus 로고    scopus 로고
    • Early progression of diabetic nephropathy correlates with methylglyoxal-derived advanced glycation end products
    • P.J. Beisswenger, S.K. Howell, G.B. Russell, M.E. Miller, S.S. Rich, and M. Mauer Early progression of diabetic nephropathy correlates with methylglyoxal-derived advanced glycation end products Diabetes Care 36 10 2013 3234 3239
    • (2013) Diabetes Care , vol.36 , Issue.10 , pp. 3234-3239
    • Beisswenger, P.J.1    Howell, S.K.2    Russell, G.B.3    Miller, M.E.4    Rich, S.S.5    Mauer, M.6
  • 173
    • 84862020461 scopus 로고    scopus 로고
    • Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
    • A. Bierhaus, T. Fleming, S. Stoyanov, A. Leffler, A. Babes, and C. Neacsu et al. Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy Nat Med 18 6 2012 926 933
    • (2012) Nat Med , vol.18 , Issue.6 , pp. 926-933
    • Bierhaus, A.1    Fleming, T.2    Stoyanov, S.3    Leffler, A.4    Babes, A.5    Neacsu, C.6
  • 174
    • 84863423974 scopus 로고    scopus 로고
    • Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ) in Parkinsonian brains
    • Y. Deng, Y. Zhang, Y. Li, S. Xiao, D. Song, and H. Qing et al. Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4- tetrahydroisoquinoline (ADTIQ) in Parkinsonian brains J Neural Transm 119 4 2012 435 441
    • (2012) J Neural Transm , vol.119 , Issue.4 , pp. 435-441
    • Deng, Y.1    Zhang, Y.2    Li, Y.3    Xiao, S.4    Song, D.5    Qing, H.6
  • 175
    • 77952585217 scopus 로고    scopus 로고
    • Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice
    • C.G. Jolivalt, R. Hurford, C.A. Lee, W. Dumaop, E. Rockenstein, and E. Masliah Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice Exp Neurol 223 2 2010 422 431
    • (2010) Exp Neurol , vol.223 , Issue.2 , pp. 422-431
    • Jolivalt, C.G.1    Hurford, R.2    Lee, C.A.3    Dumaop, W.4    Rockenstein, E.5    Masliah, E.6
  • 176
    • 84869179307 scopus 로고    scopus 로고
    • Diabetes exacerbates amyloid and neurovascular pathology in aging-accelerated mice
    • A. Currais, M. Prior, D. Lo, C. Jolivalt, D. Schubert, and P. Maher Diabetes exacerbates amyloid and neurovascular pathology in aging-accelerated mice Aging Cell 11 6 2012 1017 1026
    • (2012) Aging Cell , vol.11 , Issue.6 , pp. 1017-1026
    • Currais, A.1    Prior, M.2    Lo, D.3    Jolivalt, C.4    Schubert, D.5    Maher, P.6
  • 178
    • 84856210604 scopus 로고    scopus 로고
    • Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease
    • C.G. Jolivalt, N.A. Calcutt, and E. Masliah Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease Neuroscience 202 2012 405 412
    • (2012) Neuroscience , vol.202 , pp. 405-412
    • Jolivalt, C.G.1    Calcutt, N.A.2    Masliah, E.3
  • 179
    • 85056046161 scopus 로고    scopus 로고
    • Diabetes and Alzheimer's disease - Is there a connection?
    • A.A. Sima, and Z.G. Li Diabetes and Alzheimer's disease - is there a connection? Rev Diabet Stud 3 4 2006 161 168
    • (2006) Rev Diabet Stud , vol.3 , Issue.4 , pp. 161-168
    • Sima, A.A.1    Li, Z.G.2
  • 183
    • 84872479149 scopus 로고    scopus 로고
    • Passive immunotherapy for Alzheimer's disease: What have we learned, and where are we headed?
    • P.S. Aisen, and B. Vellas Passive immunotherapy for Alzheimer's disease: what have we learned, and where are we headed? J Nutr Health Aging 17 1 2013 49 50
    • (2013) J Nutr Health Aging , vol.17 , Issue.1 , pp. 49-50
    • Aisen, P.S.1    Vellas, B.2
  • 184
    • 77949300796 scopus 로고    scopus 로고
    • 11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: A phase 2, double-blind, placebo-controlled, ascending-dose study
    • J.O. Rinne, D.J. Brooks, M.N. Rossor, N.C. Fox, R. Bullock, and W.E. Klunk et al. 11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study Lancet Neurol 9 4 2010 363 372
    • (2010) Lancet Neurol , vol.9 , Issue.4 , pp. 363-372
    • Rinne, J.O.1    Brooks, D.J.2    Rossor, M.N.3    Fox, N.C.4    Bullock, R.5    Klunk, W.E.6
  • 186
    • 84881548115 scopus 로고    scopus 로고
    • Amyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds
    • N. Joseph-Mathurin, O. Dorieux, S.G. Trouche, A. Boutajangout, A. Kraska, and P. Fontes et al. Amyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds Neurobiol Aging 34 11 2013 2613 2622
    • (2013) Neurobiol Aging , vol.34 , Issue.11 , pp. 2613-2622
    • Joseph-Mathurin, N.1    Dorieux, O.2    Trouche, S.G.3    Boutajangout, A.4    Kraska, A.5    Fontes, P.6
  • 187
    • 80055078025 scopus 로고    scopus 로고
    • Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases
    • R.H. Swerdlow Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases Curr Pharm Des 17 31 2011 3356 3373
    • (2011) Curr Pharm des , vol.17 , Issue.31 , pp. 3356-3373
    • Swerdlow, R.H.1
  • 188
    • 84897409736 scopus 로고    scopus 로고
    • Bioenergetic medicine
    • 10.1111/bph.12394
    • R.H. Swerdlow Bioenergetic medicine Br J Pharmacol 2013 10.1111/bph.12394
    • (2013) Br J Pharmacol
    • Swerdlow, R.H.1
  • 189
    • 84877691201 scopus 로고    scopus 로고
    • Predominance of beta-cell neogenesis rather than replication in humans with an impaired glucose tolerance and newly diagnosed diabetes
    • S. Yoneda, S. Uno, H. Iwahashi, Y. Fujita, A. Yoshikawa, and J. Kozawa et al. Predominance of beta-cell neogenesis rather than replication in humans with an impaired glucose tolerance and newly diagnosed diabetes J Clin Endocrinol Metab 98 5 2013 2053 2061
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.5 , pp. 2053-2061
    • Yoneda, S.1    Uno, S.2    Iwahashi, H.3    Fujita, Y.4    Yoshikawa, A.5    Kozawa, J.6
  • 190
    • 80052572136 scopus 로고    scopus 로고
    • Diabetes prevention trial TDSG: Metabolic tests to determine risk for type 1 diabetes in clinical trials
    • C.J. Greenbaum, B. Buckingham, H.P. Chase, and J. Krischer Diabetes prevention trial TDSG: metabolic tests to determine risk for type 1 diabetes in clinical trials Diabetes Metab Res Rev 27 6 2011 584 589
    • (2011) Diabetes Metab Res Rev , vol.27 , Issue.6 , pp. 584-589
    • Greenbaum, C.J.1    Buckingham, B.2    Chase, H.P.3    Krischer, J.4
  • 192
    • 31844443761 scopus 로고    scopus 로고
    • The rise and fall of insulin secretion in type 1 diabetes mellitus
    • DOI 10.1007/s00125-005-0100-8
    • E.B. Tsai, N.A. Sherry, J.P. Palmer, and K.C. Herold The rise and fall of insulin secretion in type 1 diabetes mellitus Diabetologia 49 2 2006 261 270 (Pubitemid 43185394)
    • (2006) Diabetologia , vol.49 , Issue.2 , pp. 261-270
    • Tsai, E.B.1    Sherry, N.A.2    Palmer, J.P.3    Herold, K.C.4
  • 193
    • 0028091753 scopus 로고
    • Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus
    • H. Beck-Nielsen, and L.C. Groop Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus J Clin Invest 94 5 1994 1714 1721
    • (1994) J Clin Invest , vol.94 , Issue.5 , pp. 1714-1721
    • Beck-Nielsen, H.1    Groop, L.C.2
  • 194
    • 79953167203 scopus 로고    scopus 로고
    • Ncb5or deficiency increases fatty acid catabolism and oxidative stress
    • M. Xu, W. Wang, J.R. Frontera, M.C. Neely, J. Lu, and D. Aires et al. Ncb5or deficiency increases fatty acid catabolism and oxidative stress J Biol Chem 286 13 2011 11141 11154
    • (2011) J Biol Chem , vol.286 , Issue.13 , pp. 11141-11154
    • Xu, M.1    Wang, W.2    Frontera, J.R.3    Neely, M.C.4    Lu, J.5    Aires, D.6
  • 195
    • 84895812643 scopus 로고    scopus 로고
    • Risk estimates for complex disorders: Comparing personal genome testing and family history
    • 10.1038/gim.2013.115
    • L. Aiyar, C. Shuman, R. Hayeems, A. Dupuis, S. Pu, and S. Wodak et al. Risk estimates for complex disorders: comparing personal genome testing and family history Genet Med 2013 10.1038/gim.2013.115
    • (2013) Genet Med
    • Aiyar, L.1    Shuman, C.2    Hayeems, R.3    Dupuis, A.4    Pu, S.5    Wodak, S.6


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