-
2
-
-
34250716407
-
Mitochondrial dysfunction in Parkinson's disease
-
DOI 10.1038/sj.cdd.4402160, PII 4402160
-
Schapira A. H. V., Mitochondrial dysfunction in Parkinson's disease Cell Death and Differentiation 2007 14 7 1261 1266 (Pubitemid 46965257)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.7
, pp. 1261-1266
-
-
Schapira, A.H.V.1
-
3
-
-
0024330311
-
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease
-
Mizuno Y., Ohta S., Tanaka M., Takamiya S., Suzuki K., Sato T., Oya H., Ozawa T., Kagawa Y., Deficiencies in Complex I subunits of the respiratory chain in Parkinson's disease Biochemical and Biophysical Research Communications 1989 163 1450 1455 (Pubitemid 19244751)
-
(1989)
Biochemical and Biophysical Research Communications
, vol.163
, Issue.3
, pp. 1450-1455
-
-
Mizuno, Y.1
Ohta, S.2
Tanaka, M.3
Takamiya, S.4
Suzuki, K.5
Sato, T.6
Oya, H.7
Ozawa, T.8
Kawaga, Y.9
-
4
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A. H. V., Cooper J. M., Dexter D., Jenner P., Clark J. B., Marsden C. D., Mitochondrial Complex I deficiency in Parkinson's disease The Lancet 1989 1 8649 1269 (Pubitemid 19140359)
-
(1989)
Lancet
, vol.1
, Issue.8649
, pp. 1269
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
5
-
-
0025254401
-
Mitochondrial Complex i deficiency in Parkinson's disease
-
Schapira A. H. V., Cooper J. M., Dexter D., Clark J. B., Jenner P., Marsden C. D., Mitochondrial Complex I deficiency in Parkinson's disease Journal of Neurochemistry 1990 54 3 823 827
-
(1990)
Journal of Neurochemistry
, vol.54
, Issue.3
, pp. 823-827
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
6
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
-
DOI 10.1523/JNEUROSCI.0984-06.2006
-
Keeney P. M., Xie J., Capaldi R. A., Bennett J. P., Parkinson's disease brain mitochondrial Complex I has oxidatively damaged subunits and is functionally impaired and misassembled Journal of Neuroscience 2006 26 19 5256 5264 (Pubitemid 44315308)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.19
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett Jr., J.P.4
-
7
-
-
0026544129
-
Mitochondrial complex i and II activities of lymphocytes and platelets in Parkinson's disease
-
Yoshino H., Nakagawa-Hattori Y., Kondo T., Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease Journal of Neural Transmission 1992 4 1 27 34
-
(1992)
Journal of Neural Transmission
, vol.4
, Issue.1
, pp. 27-34
-
-
Yoshino, H.1
Nakagawa-Hattori, Y.2
Kondo, T.3
-
8
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
DOI 10.1002/ana.410260606
-
Parker W. D. Jr., Boyson S. J., Parks J. K., Abnormalities of the electron transport chain in idiopathic Parkinson's disease Annals of Neurology 1989 26 6 719 723 (Pubitemid 20011004)
-
(1989)
Annals of Neurology
, vol.26
, Issue.6
, pp. 719-723
-
-
Parker Jr., W.D.1
Boyson, S.J.2
Parks, J.K.3
-
9
-
-
0026091344
-
Mitochondrial oxidative phosphorylation defects in Parkinson's disease
-
Shoffner J. M., Watts R. L., Juncos J. L., Torroni A., Wallace D. C., Mitochondrial oxidative phosphorylation defects in Parkinson's disease Annals of Neurology 1991 30 3 332 339
-
(1991)
Annals of Neurology
, vol.30
, Issue.3
, pp. 332-339
-
-
Shoffner, J.M.1
Watts, R.L.2
Juncos, J.L.3
Torroni, A.4
Wallace, D.C.5
-
10
-
-
77950661030
-
Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer
-
Esteves A. R., Lu J., Rodova M., Onyango I., Lezi E., Dubinsky R., Lyons K. E., Pahwa R., Burns J. M., Cardoso S. M., Swerdlow R. H., Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer Journal of Neurochemistry 2010 113 3 674 682
-
(2010)
Journal of Neurochemistry
, vol.113
, Issue.3
, pp. 674-682
-
-
Esteves, A.R.1
Lu, J.2
Rodova, M.3
Onyango, I.4
Lezi, E.5
Dubinsky, R.6
Lyons, K.E.7
Pahwa, R.8
Burns, J.M.9
Cardoso, S.M.10
Swerdlow, R.H.11
-
11
-
-
0029908226
-
Origin and functional consequences of the complex I defect in Parkinson's disease
-
DOI 10.1002/ana.410400417
-
Swerdlow R. H., Parks J. K., Miller S. W., Tuttle J. B., Trimmer P. A., Sheehan J. P., Bennett J. P., Davis R. E., Parker W. D., Origin and functional consequences of the Complex I defect in Parkinson's disease Annals of Neurology 1996 40 4 663 671 (Pubitemid 26357892)
-
(1996)
Annals of Neurology
, vol.40
, Issue.4
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett Jr., J.P.7
Davis, R.E.8
Parker Jr., W.D.9
-
12
-
-
77958072667
-
PGC-1{alpha}, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
-
Zheng B., Liao Z., Locascio J. J., PGC-1{alpha}, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease Sci Transl Med 2010 2 52 52ra73
-
(2010)
Sci Transl Med
, vol.2
, Issue.52
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
-
13
-
-
0037240325
-
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
-
DOI 10.1172/JCI200317575
-
Dawson T. M., Dawson V. L., Rare genetic mutations shed light on the pathogenesis of Parkinson disease Journal of Clinical Investigation 2003 111 2 145 151 (Pubitemid 36105909)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.2
, pp. 145-151
-
-
Dawson, T.M.1
Dawson, V.L.2
-
14
-
-
0344198025
-
Mechanism of toxicity in rotenone models of Parkinson's disease
-
Sherer T. B., Betarbet R., Testa C. M., Seo B. B., Richardson J. R., Kim J. H., Miller G. W., Yagi T., Matsuno-Yagi A., Greenamyre J. T., Mechanism of toxicity in rotenone models of Parkinson's disease Journal of Neuroscience 2003 23 34 10756 10764 (Pubitemid 37499681)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.34
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
15
-
-
0035344211
-
Experimental models of Parkinson's disease
-
Beal M. F., Experimental models of Parkinson's disease Nature Reviews Neuroscience 2001 2 5 325 334
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.5
, pp. 325-334
-
-
Beal, M.F.1
-
16
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
DOI 10.1113/jphysiol.2003.049478
-
Turrens J. F., Mitochondrial formation of reactive oxygen species Journal of Physiology 2003 552 2 335 344 (Pubitemid 37321833)
-
(2003)
Journal of Physiology
, vol.552
, Issue.2
, pp. 335-344
-
-
Turrens, J.F.1
-
17
-
-
70449729372
-
DJ-1 binds to mitochondrial Complex i and maintains its activity
-
Hayashi T., Ishimori C., Takahashi-Niki K., Taira T., Kim Y. C., Maita H., Maita C., Ariga H., Iguchi-Ariga S. M. M., DJ-1 binds to mitochondrial Complex I and maintains its activity Biochemical and Biophysical Research Communications 2009 390 3 667 672
-
(2009)
Biochemical and Biophysical Research Communications
, vol.390
, Issue.3
, pp. 667-672
-
-
Hayashi, T.1
Ishimori, C.2
Takahashi-Niki, K.3
Taira, T.4
Kim, Y.C.5
Maita, H.6
Maita, C.7
Ariga, H.8
Iguchi-Ariga, S.M.M.9
-
18
-
-
79953903691
-
DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex i inhibitor-induced neurotoxicity
-
Mullett S. J., Hinkle D. A., DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity Journal of Neurochemistry 2011 117 3 375 387
-
(2011)
Journal of Neurochemistry
, vol.117
, Issue.3
, pp. 375-387
-
-
Mullett, S.J.1
Hinkle, D.A.2
-
20
-
-
84863677452
-
The evolution and role of mitochondrial fusion and fission in aging and disease
-
Kowald A., Kirkwood T. B., The evolution and role of mitochondrial fusion and fission in aging and disease Communicative Integrative Biology 2011 4 627 629
-
(2011)
Communicative Integrative Biology
, vol.4
, pp. 627-629
-
-
Kowald, A.1
Kirkwood, T.B.2
-
21
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang X., Winter D., Ashrafi G., Schlehe J., Wong Y. L., Selkoe D., Rice S., Steen J., LaVoie M. J., Schwarz T. L., PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility Cell 2011 147 893 906
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
Lavoie, M.J.9
Schwarz, T.L.10
-
22
-
-
34447289622
-
Pathogenic mutations in Parkinson disease
-
DOI 10.1002/humu.20507
-
Tan E. K., Skipper L. M., Pathogenic mutations in Parkinson disease Human Mutation 2007 28 7 641 653 (Pubitemid 47047290)
-
(2007)
Human Mutation
, vol.28
, Issue.7
, pp. 641-653
-
-
Tan, E.-K.1
Skipper, L.M.2
-
23
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos M. H., Lavedan C., Leroy E., Ide S. E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E. S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W. G., Lazzarini A. M., Duvoisin R. C., Di Iorio G., Golbe L. I., Nussbaum R. L., Mutation in the -Synuclein gene identified in families with Parkinson's disease Science 1997 276 5321 2045 2047 (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
24
-
-
77951185469
-
Genome-Wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for parkinson disease
-
Edwards T. L., Scott W. K., Almonte C., Burt A., Powell E. H., Beecham G. W., Wang L., Zchner S., Konidari I., Wang G., Singer C., Nahab F., Scott B., Stajich J. M., Pericak-Vance M., Haines J., Vance J. M., Martin E. R., Genome-Wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for parkinson disease Annals of Human Genetics 2010 74 2 97 109
-
(2010)
Annals of Human Genetics
, vol.74
, Issue.2
, pp. 97-109
-
-
Edwards, T.L.1
Scott, W.K.2
Almonte, C.3
Burt, A.4
Powell, E.H.5
Beecham, G.W.6
Wang, L.7
Zchner, S.8
Konidari, I.9
Wang, G.10
Singer, C.11
Nahab, F.12
Scott, B.13
Stajich, J.M.14
Pericak-Vance, M.15
Haines, J.16
Vance, J.M.17
Martin, E.R.18
-
25
-
-
78149489129
-
SNCA variant associated with Parkinson disease and plasma -Synuclein level
-
Mata I. F., Shi M., Agarwal P., Chung K. A., Edwards K. L., Factor S. A., Galasko D. R., Ginghina C., Griffith A., Higgins D. S., Kay D. M., Kim H., Leverenz J. B., Quinn J. F., Roberts J. W., Samii A., Snapinn K. W., Tsuang D. W., Yearout D., Zhang J., Payami H., Zabetian C. P., SNCA variant associated with Parkinson disease and plasma -Synuclein level Archives of Neurology 2010 67 11 1350 1356
-
(2010)
Archives of Neurology
, vol.67
, Issue.11
, pp. 1350-1356
-
-
Mata, I.F.1
Shi, M.2
Agarwal, P.3
Chung, K.A.4
Edwards, K.L.5
Factor, S.A.6
Galasko, D.R.7
Ginghina, C.8
Griffith, A.9
Higgins, D.S.10
Kay, D.M.11
Kim, H.12
Leverenz, J.B.13
Quinn, J.F.14
Roberts, J.W.15
Samii, A.16
Snapinn, K.W.17
Tsuang, D.W.18
Yearout, D.19
Zhang, J.20
Payami, H.21
Zabetian, C.P.22
more..
-
26
-
-
79955113404
-
Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease
-
Mata I. F., Yearout D., Alvarez V., Coto E., de Mena L., Ribacoba R., Lorenzo-Betancor O., Samaranch L., Pastor P., Cervantes S., Infante J., Garcia-Gorostiaga I., Sierra M., Combarros O., Snapinn K. W., Edwards K. L., Zabetian C. P., Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease Movement Disorders 2011 26 5 819 823
-
(2011)
Movement Disorders
, vol.26
, Issue.5
, pp. 819-823
-
-
Mata, I.F.1
Yearout, D.2
Alvarez, V.3
Coto, E.4
De Mena, L.5
Ribacoba, R.6
Lorenzo-Betancor, O.7
Samaranch, L.8
Pastor, P.9
Cervantes, S.10
Infante, J.11
Garcia-Gorostiaga, I.12
Sierra, M.13
Combarros, O.14
Snapinn, K.W.15
Edwards, K.L.16
Zabetian, C.P.17
-
27
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simn-Snchez J., Schulte C., Bras J. M., Sharma M., Gibbs J. R., Berg D., Paisan-Ruiz C., Lichtner P., Scholz S. W., Hernandez D. G., Krger R., Federoff M., Klein C., Goate A., Perlmutter J., Bonin M., Nalls M. A., Illig T., Gieger C., Houlden H., Steffens M., Okun M. S., Racette B. A., Cookson M. R., Foote K. D., Fernandez H. H., Traynor B. J., Schreiber S., Arepalli S., Zonozi R., Gwinn K., Van Der Brug M., Lopez G., Chanock S. J., Schatzkin A., Park Y., Hollenbeck A., Gao J., Huang X., Wood N. W., Lorenz D., Deuschl G., Chen H., Riess O., Hardy J. A., Singleton A. B., Gasser T., Genome-wide association study reveals genetic risk underlying Parkinson's disease Nature Genetics 2009 41 12 1308 1312
-
(2009)
Nature Genetics
, vol.41
, Issue.12
, pp. 1308-1312
-
-
Simn-Snchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.W.9
Hernandez, D.G.10
Krger, R.11
Federoff, M.12
Klein, C.13
Goate, A.14
Perlmutter, J.15
Bonin, M.16
Nalls, M.A.17
Illig, T.18
Gieger, C.19
Houlden, H.20
Steffens, M.21
Okun, M.S.22
Racette, B.A.23
Cookson, M.R.24
Foote, K.D.25
Fernandez, H.H.26
Traynor, B.J.27
Schreiber, S.28
Arepalli, S.29
Zonozi, R.30
Gwinn, K.31
Van Der Brug, M.32
Lopez, G.33
Chanock, S.J.34
Schatzkin, A.35
Park, Y.36
Hollenbeck, A.37
Gao, J.38
Huang, X.39
Wood, N.W.40
Lorenz, D.41
Deuschl, G.42
Chen, H.43
Riess, O.44
Hardy, J.A.45
Singleton, A.B.46
Gasser, T.47
more..
-
28
-
-
78650550275
-
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21
-
Spencer C. C., Plagnol V., Strange A., Gardner M., Paisan-Ruiz C., Band G., Barker R. A., Bellenguez C., Bhatia K., Blackburn H., Blackwell J. M., Bramon E., Brown M. A., Brown M. A., Burn D., Casas J. P., Chinnery P. F., Clarke C. E., Corvin A., Craddock N., Deloukas P., Edkins S., Evans J., Freeman C., Gray E., Hardy J., Hudson G., Hunt S., Jankowski J., Langford C., Lees A. J., Markus H. S., Mathew C. G., McCarthy M. I., Morrison K. E., Palmer C. N., Pearson J. P., Peltonen L., Pirinen M., Plomin R., Potter S., Rautanen A., Sawcer S. J., Su Z., Trembath R. C., Viswanathan A. C., Williams N. W., Morris H. R., Donnelly P., Wood N. W., Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21 Human Molecular Genetics 2011 20 2 345 353
-
(2011)
Human Molecular Genetics
, vol.20
, Issue.2
, pp. 345-353
-
-
Spencer, C.C.1
Plagnol, V.2
Strange, A.3
Gardner, M.4
Paisan-Ruiz, C.5
Band, G.6
Barker, R.A.7
Bellenguez, C.8
Bhatia, K.9
Blackburn, H.10
Blackwell, J.M.11
Bramon, E.12
Brown, M.A.13
Brown, M.A.14
Burn, D.15
Casas, J.P.16
Chinnery, P.F.17
Clarke, C.E.18
Corvin, A.19
Craddock, N.20
Deloukas, P.21
Edkins, S.22
Evans, J.23
Freeman, C.24
Gray, E.25
Hardy, J.26
Hudson, G.27
Hunt, S.28
Jankowski, J.29
Langford, C.30
Lees, A.J.31
Markus, H.S.32
Mathew, C.G.33
McCarthy, M.I.34
Morrison, K.E.35
Palmer, C.N.36
Pearson, J.P.37
Peltonen, L.38
Pirinen, M.39
Plomin, R.40
Potter, S.41
Rautanen, A.42
Sawcer, S.J.43
Su, Z.44
Trembath, R.C.45
Viswanathan, A.C.46
Williams, N.W.47
Morris, H.R.48
Donnelly, P.49
Wood, N.W.50
more..
-
29
-
-
77958482255
-
The N-terminus of the intrinsically disordered protein -Synuclein triggers membrane binding and helix folding
-
Bartels T., Ahlstrom L. S., Leftin A., Kamp F., Haass C., Brown M. F., Beyer K., The N-terminus of the intrinsically disordered protein -Synuclein triggers membrane binding and helix folding Biophysical Journal 2010 99 7 2116 2124
-
(2010)
Biophysical Journal
, vol.99
, Issue.7
, pp. 2116-2124
-
-
Bartels, T.1
Ahlstrom, L.S.2
Leftin, A.3
Kamp, F.4
Haass, C.5
Brown, M.F.6
Beyer, K.7
-
30
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Farias I., Choi-Lundberg D., Ho W. H., Castillo P. E., Shinsky N., Garcia Verdugo J. M., Armanini M., Ryan A., Hynes M., Phillips H., Sulzer D., Rosenthal A., Mice lacking -Synuclein display functional deficits in the nigrostriatal dopamine system Neuron 2000 25 1 239 252 (Pubitemid 30316525)
-
(2000)
Neuron
, vol.25
, Issue.1
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.-H.5
Castillo, P.E.6
Shinsky, N.7
Garcia Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
31
-
-
0033771793
-
Is there a cause-and-effect relationship between -Synuclein fibrillization and Parkinson's disease?
-
Goldberg M. S., Lansbury P. T., Is there a cause-and-effect relationship between -Synuclein fibrillization and Parkinson's disease? Nature Cell Biology 2000 2 7 E115 E119
-
(2000)
Nature Cell Biology
, vol.2
, Issue.7
-
-
Goldberg, M.S.1
Lansbury, P.T.2
-
33
-
-
33746533924
-
α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
DOI 10.1126/science.1129462
-
Cooper A. A., Gitler A. D., Cashikar A., Haynes C. M., Hill K. J., Bhullar B., Liu K., Xu K., Strathearn K. E., Liu F., Cao S., Caldwell K. A., Caldwell G. A., Marsischky G., Kolodner R. D., LaBaer J., Rochet J. C., Bonini N. M., Lindquist S., -Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models Science 2006 313 5785 324 328 (Pubitemid 44480951)
-
(2006)
Science
, vol.313
, Issue.5785
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
Bhullar, B.6
Liu, K.7
Xu, K.8
Strathearn, K.E.9
Liu, F.10
Cao, S.11
Caldwell, K.A.12
Caldwell, G.A.13
Marsischky, G.14
Kolodner, R.D.15
LaBaer, J.16
Rochet, J.-C.17
Bonini, N.M.18
Lindquist, S.19
-
34
-
-
38849174979
-
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
-
DOI 10.1172/JCI32806
-
Martinez-Vicente M., Talloczy Z., Kaushik S., Massey A. C., Mazzulli J., Mosharov E. V., Hodara R., Fredenburg R., Wu D. C., Follenzi A., Dauer W., Przedborski S., Ischiropoulos H., Lansbury P. T., Sulzer D., Cuervo A. M., Dopamine-modified -Synuclein blocks chaperone-mediated autophagy Journal of Clinical Investigation 2008 118 2 777 778 (Pubitemid 351206565)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 777-778
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
Massey, A.C.4
Mazzulli, J.5
Mosharov, E.V.6
Hodara, R.7
Fredenburg, R.8
Wu, D.-C.9
Follenzi, A.10
Dauer, W.11
Przedborski, S.12
Ischiropoulos, H.13
Lansbury, P.T.14
Sulzer, D.15
Cuervo, A.M.16
-
35
-
-
0037227397
-
Altered proteasomal function in sporadic Parkinson's disease
-
DOI 10.1006/exnr.2002.8050
-
McNaught K. S. P., Belizaire R., Isacson O., Jenner P., Olanow C. W., Altered proteasomal function in sporadic Parkinson's disease Experimental Neurology 2003 179 1 38 46 (Pubitemid 36062617)
-
(2003)
Experimental Neurology
, vol.179
, Issue.1
, pp. 38-46
-
-
McNaught, K.St.P.1
Belizaire, R.2
Isacson, O.3
Jenner, P.4
Olanow, C.W.5
-
36
-
-
0033890821
-
α-Synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu L. J., Sagara Y., Arroyo A., Rockenstein E., Sisk A., Mallory M., Wong J., Takenouchi T., Hashimoto M., Masliah E., -Synuclein promotes mitochondrial deficit and oxidative stress The American Journal of Pathology 2000 157 2 401 410 (Pubitemid 30627559)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
37
-
-
1542617769
-
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP
-
DOI 10.1016/S0014-4886(03)00342-X, PII S001448860300342X
-
Song D. D., Shults C. W., Sisk A., Rockenstein E., Masliah E., Enhanced substantia nigra mitochondrial pathology in human -Synuclein transgenic mice after treatment with MPTP Experimental Neurology 2004 186 2 158 172 (Pubitemid 38333191)
-
(2004)
Experimental Neurology
, vol.186
, Issue.2
, pp. 158-172
-
-
Song, D.D.1
Shults, C.W.2
Sisk, A.3
Rockenstein, E.4
Masliah, E.5
-
38
-
-
77949438990
-
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models
-
Su L. J., Auluck P. K., Outeiro T. F., Yeger-Lotem E., Kritzer J. A., Tardiff D. F., Strathearn K. E., Liu F., Cao S., Hamamichi S., Hill K. J., Caldwell K. A., Bell G. W., Fraenkel E., Cooper A. A., Caldwell G. A., Michael McCaffery J., Rochet J. C., Lindquist S., Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models DMM Disease Models and Mechanisms 2010 3 3-4 194 208
-
(2010)
DMM Disease Models and Mechanisms
, vol.3
, Issue.34
, pp. 194-208
-
-
Su, L.J.1
Auluck, P.K.2
Outeiro, T.F.3
Yeger-Lotem, E.4
Kritzer, J.A.5
Tardiff, D.F.6
Strathearn, K.E.7
Liu, F.8
Cao, S.9
Hamamichi, S.10
Hill, K.J.11
Caldwell, K.A.12
Bell, G.W.13
Fraenkel, E.14
Cooper, A.A.15
Caldwell, G.A.16
Michael McCaffery, J.17
Rochet, J.C.18
Lindquist, S.19
-
39
-
-
44649150145
-
Mitochondrial localization of alpha-Synuclein protein in alpha-Synuclein overexpressing cells
-
Shavali S., Brown-Borg H. M., Ebadi M., Porter J., Mitochondrial localization of alpha-Synuclein protein in alpha-Synuclein overexpressing cells Neuroscience Letters 2008 439 2 125 128
-
(2008)
Neuroscience Letters
, vol.439
, Issue.2
, pp. 125-128
-
-
Shavali, S.1
Brown-Borg, H.M.2
Ebadi, M.3
Porter, J.4
-
40
-
-
34748826792
-
Localization of α-synuclein to mitochondria within midbrain of mice
-
DOI 10.1097/WNR.0b013e3282f03db4, PII 0000175620071008000007
-
Li W. W., Yang R., Guo J. C., Ren H. M., Zha X. L., Cheng J. S., Cai D. F., Localization of -Synuclein to mitochondria within midbrain of mice NeuroReport 2007 18 15 1543 1546 (Pubitemid 47476380)
-
(2007)
NeuroReport
, vol.18
, Issue.15
, pp. 1543-1546
-
-
Li, W.-W.1
Yang, R.2
Guo, J.-C.3
Ren, H.-M.4
Zha, X.-L.5
Cheng, J.-S.6
Cai, D.-F.7
-
41
-
-
79960279832
-
Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
-
Pranke I. M., Morello V., Bigay J., Gibson K., Verbavatz J. M., Antonny B., Jackson C. L., Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding Journal of Cell Biology 2011 194 1 89 103
-
(2011)
Journal of Cell Biology
, vol.194
, Issue.1
, pp. 89-103
-
-
Pranke, I.M.1
Morello, V.2
Bigay, J.3
Gibson, K.4
Verbavatz, J.M.5
Antonny, B.6
Jackson, C.L.7
-
42
-
-
44749085250
-
Mitochondrial translocation of -Synuclein is promoted by intracellular acidification
-
Cole N. B., DiEuliis D., Leo P., Mitchell D. C., Nussbaum R. L., Mitochondrial translocation of -Synuclein is promoted by intracellular acidification Experimental Cell Research 2008 314 10 2076 2089
-
(2008)
Experimental Cell Research
, vol.314
, Issue.10
, pp. 2076-2089
-
-
Cole, N.B.1
Dieuliis, D.2
Leo, P.3
Mitchell, D.C.4
Nussbaum, R.L.5
-
43
-
-
44049099669
-
Mitochondrial import and accumulation of -Synuclein impair Complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi L., Raghavendran V., Prabhu B. M., Avadhani N. G., Anandatheerthavarada H. K., Mitochondrial import and accumulation of -Synuclein impair Complex I in human dopaminergic neuronal cultures and Parkinson disease brain Journal of Biological Chemistry 2008 283 14 9089 9100
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.14
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
44
-
-
71949090833
-
Mitochondrial trafficking of APP and alpha-Synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases
-
Devi L., Anandatheerthavarada H. K., Mitochondrial trafficking of APP and alpha-Synuclein: relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases Biochimica et Biophysica Acta 2010 1802 1 11 19
-
(2010)
Biochimica et Biophysica Acta
, vol.1802
, Issue.1
, pp. 11-19
-
-
Devi, L.1
Anandatheerthavarada, H.K.2
-
45
-
-
77958450202
-
Inhibition of mitochondrial fusion by -Synuclein is rescued by PINK1, Parkin and DJ-1
-
Kamp F., Exner N., Lutz A. K., Wender N., Hegermann J., Brunner B., Nuscher B., Bartels T., Giese A., Beyer K., Eimer S., Winklhofer K. F., Haass C., Inhibition of mitochondrial fusion by -Synuclein is rescued by PINK1, Parkin and DJ-1 The EMBO Journal 2010 29 20 3571 3589
-
(2010)
The EMBO Journal
, vol.29
, Issue.20
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
Eimer, S.11
Winklhofer, K.F.12
Haass, C.13
-
46
-
-
63449093494
-
Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates Complex i activity
-
Liu G., Zhang C., Yin J., Li X., Cheng F., Li Y., Yang H., Uéda K., Chan P., Yu S., Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates Complex I activity Neuroscience Letters 2009 454 3 187 192
-
(2009)
Neuroscience Letters
, vol.454
, Issue.3
, pp. 187-192
-
-
Liu, G.1
Zhang, C.2
Yin, J.3
Li, X.4
Cheng, F.5
Li, Y.6
Yang, H.7
Uéda, K.8
Chan, P.9
Yu, S.10
-
47
-
-
79957974579
-
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein -synuclein
-
Nakamura K., Nemani V. M., Azarbal F., Skibinski G., Levy J. M., Egami K., Munishkina L., Zhang J., Gardner B., Wakabayashi J., Sesaki H., Cheng Y., Finkbeiner S., Nussbaum R. L., Masliah E., Edwards R. H., Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein -synuclein Journal of Biological Chemistry 2011 286 23 20710 20726
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.23
, pp. 20710-20726
-
-
Nakamura, K.1
Nemani, V.M.2
Azarbal, F.3
Skibinski, G.4
Levy, J.M.5
Egami, K.6
Munishkina, L.7
Zhang, J.8
Gardner, B.9
Wakabayashi, J.10
Sesaki, H.11
Cheng, Y.12
Finkbeiner, S.13
Nussbaum, R.L.14
Masliah, E.15
Edwards, R.H.16
-
48
-
-
41749104745
-
Complex I deficiency in Parkinson's disease frontal cortex
-
DOI 10.1016/j.brainres.2007.10.061, PII S0006899307025814
-
Parker W. D., Parks J. K., Swerdlow R. H., Complex I deficiency in Parkinson's disease frontal cortex Brain Research 2008 1189 1 215 218 (Pubitemid 351842538)
-
(2008)
Brain Research
, vol.1189
, Issue.1
, pp. 215-218
-
-
Parker Jr., W.D.1
Parks, J.K.2
Swerdlow, R.H.3
-
49
-
-
77951239770
-
The transgenic overexpression of -Synuclein and not its related pathology associates with Complex i inhibition
-
Loeb V., Yakunin E., Saada A., Sharon R., The transgenic overexpression of -Synuclein and not its related pathology associates with Complex I inhibition Journal of Biological Chemistry 2010 285 10 7334 7343
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.10
, pp. 7334-7343
-
-
Loeb, V.1
Yakunin, E.2
Saada, A.3
Sharon, R.4
-
50
-
-
78049383132
-
Mitochondrial alpha-Synuclein accumulation impairs Complex i function in dopaminergic neurons and results in increased mitophagy in vivo
-
Chinta S. J., Mallajosyula J. K., Rane A., Andersen J. K., Mitochondrial alpha-Synuclein accumulation impairs Complex I function in dopaminergic neurons and results in increased mitophagy in vivo Neuroscience Letters 2010 486 3 235 239
-
(2010)
Neuroscience Letters
, vol.486
, Issue.3
, pp. 235-239
-
-
Chinta, S.J.1
Mallajosyula, J.K.2
Rane, A.3
Andersen, J.K.4
-
51
-
-
0035834655
-
Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins
-
Perrin R. J., Woods W. S., Clayton D. F., George J. M., Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins Journal of Biological Chemistry 2001 276 45 41958 41962
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.45
, pp. 41958-41962
-
-
Perrin, R.J.1
Woods, W.S.2
Clayton, D.F.3
George, J.M.4
-
52
-
-
77951290337
-
Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson's disease
-
Banerjee K., Sinha M., Pham C. L. L., Jana S., Chanda D., Cappai R., Chakrabarti S., Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: implications in Parkinson's disease FEBS Letters 2010 584 8 1571 1576
-
(2010)
FEBS Letters
, vol.584
, Issue.8
, pp. 1571-1576
-
-
Banerjee, K.1
Sinha, M.2
Pham, C.L.L.3
Jana, S.4
Chanda, D.5
Cappai, R.6
Chakrabarti, S.7
-
53
-
-
68949151944
-
Alpha-Synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
-
Parihar M. S., Parihar A., Fujita M., Hashimoto M., Ghafourifar P., Alpha-Synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells International Journal of Biochemistry and Cell Biology 2009 41 10 2015 2024
-
(2009)
International Journal of Biochemistry and Cell Biology
, vol.41
, Issue.10
, pp. 2015-2024
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
54
-
-
78651287877
-
Making heads or tails of phospholipids in mitochondria
-
Osman C., Voelker D. R., Langer T., Making heads or tails of phospholipids in mitochondria Journal of Cell Biology 2011 192 1 7 16
-
(2011)
Journal of Cell Biology
, vol.192
, Issue.1
, pp. 7-16
-
-
Osman, C.1
Voelker, D.R.2
Langer, T.3
-
55
-
-
84856839349
-
Deficiency of cardiolipin synthase causes abnormal mitochondrial function and morphology in germ cells of Caenorhabditis elegans
-
Sakamoto T., Inoue T., Otomo Y., Yokomori N., Ohno M., Arai H., Nakagawa Y., Deficiency of cardiolipin synthase causes abnormal mitochondrial function and morphology in germ cells of Caenorhabditis elegans The Journal of Biological Chemistry 2012 287 7 4590 4601
-
(2012)
The Journal of Biological Chemistry
, vol.287
, Issue.7
, pp. 4590-4601
-
-
Sakamoto, T.1
Inoue, T.2
Otomo, Y.3
Yokomori, N.4
Ohno, M.5
Arai, H.6
Nakagawa, Y.7
-
56
-
-
0034698098
-
Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function
-
DOI 10.1074/jbc.M909868199
-
Jiang F., Ryan M. T., Schlame M., Zhao M., Gu Z., Klingenberg M., Pfanner N., Greenberg M. L., Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function Journal of Biological Chemistry 2000 275 29 22387 22394 (Pubitemid 30621825)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 22387-22394
-
-
Jiang, F.1
Ryan, M.T.2
Schlame, M.3
Zhao, M.4
Gu, Z.5
Klingenberg, M.6
Pfanner, N.7
Greenberg, M.L.8
-
57
-
-
0019887784
-
Cardiolipin requirement for electron transfer in Complex i and III of the mitochondrial respiratory chain
-
Fry M., Green D. E., Cardiolipin requirement for electron transfer in Complex I and III of the mitochondrial respiratory chain. Journal of Biological Chemistry 1981 256 4 1874 1880
-
(1981)
Journal of Biological Chemistry
, vol.256
, Issue.4
, pp. 1874-1880
-
-
Fry, M.1
Green, D.E.2
-
58
-
-
27644578107
-
Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking α-synuclein
-
DOI 10.1128/MCB.25.22.10190-10201.2005
-
Ellis C. E., Murphy E. J., Mitchell D. C., Golovko M. Y., Scaglia F., Barcel-Coblijn G. C., Nussbaum R. L., Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking -Synuclein Molecular and Cellular Biology 2005 25 22 10190 10201 (Pubitemid 41572763)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.22
, pp. 10190-10201
-
-
Ellis, C.E.1
Murphy, E.J.2
Mitchell, D.C.3
Golovko, M.Y.4
Scaglia, F.5
Barcelo-Coblijn, G.C.6
Nussbaum, R.L.7
-
59
-
-
67649756320
-
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease
-
Beler H., Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease Experimental Neurology 2009 218 2 235 246
-
(2009)
Experimental Neurology
, vol.218
, Issue.2
, pp. 235-246
-
-
Beler, H.1
-
60
-
-
77957189194
-
Synuclein impairs macroautophagy: Implications for Parkinson's disease
-
Winslow A. R., Chen C. W., Corrochano S., Acevedo-Arozena A., Gordon D. E., Peden A. A., Lichtenberg M., Menzies F. M., Ravikumar B., Imarisio S., Brown S., O'Kane C. J., Rubinsztein D. C., Synuclein impairs macroautophagy: implications for Parkinson's disease Journal of Cell Biology 2010 190 6 1023 1037
-
(2010)
Journal of Cell Biology
, vol.190
, Issue.6
, pp. 1023-1037
-
-
Winslow, A.R.1
Chen, C.W.2
Corrochano, S.3
Acevedo-Arozena, A.4
Gordon, D.E.5
Peden, A.A.6
Lichtenberg, M.7
Menzies, F.M.8
Ravikumar, B.9
Imarisio, S.10
Brown, S.11
O'Kane, C.J.12
Rubinsztein, D.C.13
-
61
-
-
79953202481
-
Mutant A53T -Synuclein induces neuronal death by increasing mitochondrial autophagy
-
Choubey V., Safiulina D., Vaarmann A., Cagalinec M., Wareski P., Kuum M., Zharkovsky A., Kaasik A., Mutant A53T -Synuclein induces neuronal death by increasing mitochondrial autophagy Journal of Biological Chemistry 2011 286 12 10814 10824
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.12
, pp. 10814-10824
-
-
Choubey, V.1
Safiulina, D.2
Vaarmann, A.3
Cagalinec, M.4
Wareski, P.5
Kuum, M.6
Zharkovsky, A.7
Kaasik, A.8
-
62
-
-
57649195400
-
Autophagy and multivesicular bodies: Two closely related partners
-
Fader C. M., Colombo M. I., Autophagy and multivesicular bodies: two closely related partners Cell Death and Differentiation 2009 16 1 70 78
-
(2009)
Cell Death and Differentiation
, vol.16
, Issue.1
, pp. 70-78
-
-
Fader, C.M.1
Colombo, M.I.2
-
63
-
-
0035490884
-
The endocytic pathway: A mosaic of domains
-
DOI 10.1038/35096054
-
Gruenberg J., The endocytic pathway: a mosaic of domains Nature Reviews Molecular Cell Biology 2001 2 10 721 730 (Pubitemid 33679834)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.10
, pp. 721-730
-
-
Gruenberg, J.1
-
64
-
-
33750902737
-
The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control
-
DOI 10.1089/ars.2006.8.1391
-
Grlach A., Klappa P., Kietzmann T., The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control Antioxidants and Redox Signaling 2006 8 9-10 1391 1418 (Pubitemid 44726319)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.9-10
, pp. 1391-1418
-
-
Gorlach, A.1
Klappa, P.2
Kietzmann, T.3
-
65
-
-
67749122635
-
An ER-mitochondria tethering complex revealed by a synthetic biology screen
-
Kornmann B., Currie E., Collins S. R., Schuldiner M., Nunnari J., Weissman J. S., Walter P., An ER-mitochondria tethering complex revealed by a synthetic biology screen Science 2009 325 5939 477 481
-
(2009)
Science
, vol.325
, Issue.5939
, pp. 477-481
-
-
Kornmann, B.1
Currie, E.2
Collins, S.R.3
Schuldiner, M.4
Nunnari, J.5
Weissman, J.S.6
Walter, P.7
-
66
-
-
73849141134
-
Shaping the mitochondrion: Mitochondrial biogenesis, dynamics and dysfunction. Conference on mitochondrial assembly and dynamics in health and disease
-
Shaw J. M., Winge D. R., Shaping the mitochondrion: mitochondrial biogenesis, dynamics and dysfunction. Conference on mitochondrial assembly and dynamics in health and disease EMBO Reports 2009 10 12 1301 1305
-
(2009)
EMBO Reports
, vol.10
, Issue.12
, pp. 1301-1305
-
-
Shaw, J.M.1
Winge, D.R.2
-
67
-
-
67649342203
-
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: Relevance to Parkinson's disease
-
Arduno D. M., Esteves A. R., Cardoso S. M., Oliveira C. R., Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease Neurochemistry International 2009 55 5 341 348
-
(2009)
Neurochemistry International
, vol.55
, Issue.5
, pp. 341-348
-
-
Arduno, D.M.1
Esteves, A.R.2
Cardoso, S.M.3
Oliveira, C.R.4
-
68
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
Friedman J. R., Lackner L. L., West M., DiBenedetto J. R., Nunnari J., Voeltz G.K., ER tubules mark sites of mitochondrial division Science 2011 334 358 362
-
(2011)
Science
, vol.334
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
Dibenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
69
-
-
33846605587
-
Activation of the unfolded protein response in Parkinson's disease
-
DOI 10.1016/j.bbrc.2007.01.043, PII S0006291X07000708
-
Hoozemans J. J. M., van Haastert E. S., Eikelenboom P., de Vos R. A. I., Rozemuller J. M., Scheper W., Activation of the unfolded protein response in Parkinson's disease Biochemical and Biophysical Research Communications 2007 354 3 707 711 (Pubitemid 46186242)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.354
, Issue.3
, pp. 707-711
-
-
Hoozemans, J.J.M.1
Van Haastert, E.S.2
Eikelenboom, P.3
De Vos, R.A.I.4
Rozemuller, J.M.5
Scheper, W.6
-
70
-
-
77952900626
-
Synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs
-
Thayanidhi N., Helm J. R., Nycz D. C., Bentley M., Liang Y., Hay J. C., -Synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs Molecular Biology of the Cell 2010 21 11 1850 1863
-
(2010)
Molecular Biology of the Cell
, vol.21
, Issue.11
, pp. 1850-1863
-
-
Thayanidhi, N.1
Helm, J.R.2
Nycz, D.C.3
Bentley, M.4
Liang, Y.5
Hay, J.C.6
-
71
-
-
84862217471
-
Mitochondria at the interface between danger signaling and metabolism: Role of unfolded protein responses in chronic inflammation
-
In press
-
Rath E., Haller D., Mitochondria at the interface between danger signaling and metabolism: role of unfolded protein responses in chronic inflammation. Inflammatory Bowel Diseases. In press
-
Inflammatory Bowel Diseases
-
-
Rath, E.1
Haller, D.2
-
72
-
-
24344433558
-
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma
-
Chiang P. C., Chien C. L., Pan S. L., Chen W. P., Teng C. M., Shen Y. C., Guh J. H., Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma Journal of Hepatology 2005 43 4 679 686
-
(2005)
Journal of Hepatology
, vol.43
, Issue.4
, pp. 679-686
-
-
Chiang, P.C.1
Chien, C.L.2
Pan, S.L.3
Chen, W.P.4
Teng, C.M.5
Shen, Y.C.6
Guh, J.H.7
-
73
-
-
77955824765
-
An intimate liaison: Spatial organization of the endoplasmic reticulum-mitochondria relationship
-
De Brito O. M., Scorrano L., An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship The EMBO Journal 2010 29 16 2715 2723
-
(2010)
The EMBO Journal
, vol.29
, Issue.16
, pp. 2715-2723
-
-
De Brito, O.M.1
Scorrano, L.2
-
74
-
-
0034194189
-
Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria
-
DOI 10.1042/0264-6021:3470687
-
Koshkin V., Greenberg M. L., Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria Biochemical Journal 2000 347 3 687 691 (Pubitemid 30260957)
-
(2000)
Biochemical Journal
, vol.347
, Issue.3
, pp. 687-691
-
-
Koshkin, V.1
Greenberg, M.L.2
-
75
-
-
84856056846
-
Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration
-
Sheng Z. H., Cai Q., Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration Nature Reviews Neuroscience 2012 13 77 93
-
(2012)
Nature Reviews Neuroscience
, vol.13
, pp. 77-93
-
-
Sheng, Z.H.1
Cai, Q.2
-
76
-
-
77956966416
-
Molecular interaction of -Synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells
-
Zhou R. M., Huang Y. X., Li X. L., Molecular interaction of -Synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells Molecular Biology Reports 2010 37 7 3183 3192
-
(2010)
Molecular Biology Reports
, vol.37
, Issue.7
, pp. 3183-3192
-
-
Zhou, R.M.1
Huang, Y.X.2
Li, X.L.3
-
77
-
-
33947625072
-
Oligomeric α-synuclein inhibits tubulin polymerization
-
DOI 10.1016/j.bbrc.2007.02.163, PII S0006291X07004615
-
Chen L., Jin J., Davis J., Zhou Y., Wang Y., Liu J., Lockhart P. J., Zhang J., Oligomeric alpha-Synuclein inhibits tubulin polymerization Biochemical and Biophysical Research Communications 2007 356 548 553 (Pubitemid 46499002)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.356
, Issue.3
, pp. 548-553
-
-
Chen, L.1
Jin, J.2
Davis, J.3
Zhou, Y.4
Wang, Y.5
Liu, J.6
Lockhart, P.J.7
Zhang, J.8
-
78
-
-
4644249092
-
Demonstration of a role for α-synuclein as a functional microtubule-associated protein
-
Alim M. A., Ma Q. L., Takeda K., Aizawa T., Matsubara M., Nakamura M., Asada A., Saito T., Kaji H., Yoshii M., Hisanaga S., Uéda K., Demonstration of a role for -Synuclein as a functional microtubule-associated protein Journal of Alzheimer's Disease 2004 6 4 435 442. discussion 443449 (Pubitemid 39287257)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.4
, pp. 435-442
-
-
Alim, M.A.1
Ma, Q.L.2
Takeda, K.3
Aizawa, T.4
Matsubara, M.5
Nakamura, M.6
Asada, A.7
Saito, T.8
Kaji, H.9
Yoshii, M.10
Hisanaga, S.11
Ueda, K.12
-
80
-
-
36849008768
-
Impairment of microtubule system increases α-synuclein aggregation and toxicity
-
DOI 10.1016/j.bbrc.2007.11.020, PII S0006291X07024060
-
Kim M., Jung W., Lee I. H., Bhak G., Paik S.R., Hahn J. S., Impairment of microtubule system increases alpha-Synuclein aggregation and toxicity Biochemical and Biophysical Research Communications 2008 365 628 635 (Pubitemid 350234838)
-
(2008)
Biochemical and Biophysical Research Communications
, vol.365
, Issue.4
, pp. 628-635
-
-
Kim, M.1
Jung, W.2
Lee, I.-H.3
Bhak, G.4
Paik, S.R.5
Hahn, J.-S.6
-
81
-
-
79958164975
-
Neuroprotective upregulation of endogenous alpha-Synuclein precedes ubiquitination in cultured dopaminergic neurons
-
Musgrove R. E. J., King A. E., Dickson T. C., Neuroprotective upregulation of endogenous alpha-Synuclein precedes ubiquitination in cultured dopaminergic neurons Neurotoxicity Research 2011 19 4 592 602
-
(2011)
Neurotoxicity Research
, vol.19
, Issue.4
, pp. 592-602
-
-
Musgrove, R.E.J.1
King, A.E.2
Dickson, T.C.3
-
82
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu E. J., Harding H. P., Angelastro J. M., Vitolo O. V., Ron D., Greene L. A., Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease Journal of Neuroscience 2002 22 24 10690 10698 (Pubitemid 36005143)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.24
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
Vitolo, O.V.4
Ron, D.5
Greene, L.A.6
-
83
-
-
56949089426
-
Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: A molecular mechanism leading to hepatic insulin resistance
-
Lim J. H., Lee H. J., Ho Jung M., Song J., Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance Cellular Signalling 2009 21 1 169 177
-
(2009)
Cellular Signalling
, vol.21
, Issue.1
, pp. 169-177
-
-
Lim, J.H.1
Lee, H.J.2
Ho Jung, M.3
Song, J.4
-
84
-
-
79957689114
-
ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells
-
Lee J. W., Kim W. H., Yeo J., Jung M. H., ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells. Molecules and cells 2010 30 6 545 549
-
(2010)
Molecules and Cells
, vol.30
, Issue.6
, pp. 545-549
-
-
Lee, J.W.1
Kim, W.H.2
Yeo, J.3
Jung, M.H.4
-
85
-
-
78751701091
-
Raised calcium promotes -Synuclein aggregate formation
-
Nath S., Goodwin J., Engelborghs Y., Pountney D. L., Raised calcium promotes -Synuclein aggregate formation Molecular and Cellular Neuroscience 2011 46 2 516 526
-
(2011)
Molecular and Cellular Neuroscience
, vol.46
, Issue.2
, pp. 516-526
-
-
Nath, S.1
Goodwin, J.2
Engelborghs, Y.3
Pountney, D.L.4
-
86
-
-
84862833343
-
Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by beta-lapachone treatment
-
Lee H., Park M. T., Choi B.H., Oh E. T., Song M. J., Lee J., Kim C., Lim B. U., Park H. J., Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by beta-lapachone treatment PLoS One 2011 6
-
(2011)
PLoS One
, vol.6
-
-
Lee, H.1
Park, M.T.2
Choi, B.H.3
Oh, E.T.4
Song, M.J.5
Lee, J.6
Kim, C.7
Lim, B.U.8
Park, H.J.9
-
87
-
-
0032560572
-
Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione
-
DOI 10.1073/pnas.95.13.7631
-
Clementi E., Brown G. C., Feelisch M., Moncada S., Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial Complex I and protective action of glutathione Proceedings of the National Academy of Sciences of the United States of America 1998 95 13 7631 7636 (Pubitemid 28293304)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.13
, pp. 7631-7636
-
-
Clementi, E.1
Brown, G.C.2
Feelisch, M.3
Moncada, S.4
-
88
-
-
79952860820
-
S-nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases
-
Nakamura T., Lipton S. A., S-nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases Antioxidants and Redox Signaling 2011 14 8 1479 1492
-
(2011)
Antioxidants and Redox Signaling
, vol.14
, Issue.8
, pp. 1479-1492
-
-
Nakamura, T.1
Lipton, S.A.2
-
89
-
-
77956298994
-
Nitrated -Synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats
-
Yu Z., Xu X., Xiang Z., Zhou J., Zhang Z., Hu C., He C., Nitrated -Synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats PLoS ONE 2010 5 4
-
(2010)
PLoS ONE
, vol.5
, Issue.4
-
-
Yu, Z.1
Xu, X.2
Xiang, Z.3
Zhou, J.4
Zhang, Z.5
Hu, C.6
He, C.7
-
90
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective -Synuclein nitration in synucleinopathy lesions
-
Giasson B. I., Duda J. E., Murray I. V. J., Chen Q., Souza J. M., Hurtig H. I., Ischiropoulos H., Trojanowski J. Q., Lee V. M. Y., Oxidative damage linked to neurodegeneration by selective -Synuclein nitration in synucleinopathy lesions Science 2000 290 5493 985 989
-
(2000)
Science
, vol.290
, Issue.5493
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.J.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.Y.9
-
91
-
-
12244299912
-
Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study
-
DOI 10.1093/hmg/ddg009
-
Levecque C., Elbaz A., Clavel J., Richard F., Vidal J. S., Amouyel P., Tzourio C., Alpérovitch A., Chartier-Harlin M. C., Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study Human Molecular Genetics 2003 12 1 79 86 (Pubitemid 36104179)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.1
, pp. 79-86
-
-
Levecque, C.1
Elbaz, A.2
Clavel, J.3
Richard, F.4
Vidal, J.-S.5
Amouyel, P.6
Tzourio, C.7
Alperovitch, A.8
Chartier-Harlin, M.-C.9
-
92
-
-
79959886743
-
Complex inhibitory effects of nitric oxide on autophagy
-
Sarkar S., Korolchuk V. I., Renna M., Imarisio S., Fleming A., Williams A., Garcia-Arencibia M., Rose C., Luo S., Underwood B. R., Kroemer G., O'Kane C. J., Rubinsztein D. C., Complex inhibitory effects of nitric oxide on autophagy Molecular Cell 2011 43 1 19 32
-
(2011)
Molecular Cell
, vol.43
, Issue.1
, pp. 19-32
-
-
Sarkar, S.1
Korolchuk, V.I.2
Renna, M.3
Imarisio, S.4
Fleming, A.5
Williams, A.6
Garcia-Arencibia, M.7
Rose, C.8
Luo, S.9
Underwood, B.R.10
Kroemer, G.11
O'Kane, C.J.12
Rubinsztein, D.C.13
-
93
-
-
79955685287
-
Allostery in a disordered protein: Oxidative modifications to -Synuclein act distally to regulate membrane binding
-
Sevcsik E., Trexler A. J., Dunn J. M., Rhoades E., Allostery in a disordered protein: oxidative modifications to -Synuclein act distally to regulate membrane binding Journal of the American Chemical Society 2011 133 18 7152 7158
-
(2011)
Journal of the American Chemical Society
, vol.133
, Issue.18
, pp. 7152-7158
-
-
Sevcsik, E.1
Trexler, A.J.2
Dunn, J.M.3
Rhoades, E.4
-
94
-
-
15544381031
-
Effects of nitration on the structure and aggregation of α-synuclein
-
DOI 10.1016/j.molbrainres.2004.11.014
-
Uversky V. N., Yamin G., Munishkina L. A., Karymov M. A., Millett I. S., Doniach S., Lyubchenko Y. L., Fink A. L., Effects of nitration on the structure and aggregation of -Synuclein Molecular Brain Research 2005 134 1 84 102 (Pubitemid 40403641)
-
(2005)
Molecular Brain Research
, vol.134
, Issue.1
, pp. 84-102
-
-
Uversky, V.N.1
Yamin, G.2
Munishkina, L.A.3
Karymov, M.A.4
Millett, I.S.5
Doniach, S.6
Lyubchenko, Y.L.7
Fink, A.L.8
-
95
-
-
0038711511
-
Effects of oxidative and nitrative challenges on α-synuclein fibrillogenesis involve distinct mechanisms of protein modifications
-
DOI 10.1074/jbc.M212436200
-
Norris E. H., Giasson B. I., Ischiropoulos H., Lee V. M. Y., Effects of oxidative and nitrative challenges on -Synuclein fibrillogenesis involve distinct mechanisms of protein modifications Journal of Biological Chemistry 2003 278 29 27230 27240 (Pubitemid 36876880)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 27230-27240
-
-
Norris, E.H.1
Giasson, B.I.2
Ischiropoulos, H.3
Lee, V.M.-Y.4
|