Frataxin deficiency in pancreatic islets causes diabetes due to loss of β cell mass

Journal of Clinical Investigation

Volumn 112, Issue 4, 2003, Pages 527-534

  Ristow, Michael ^a,b   Mulder, Hindrik ^c   Pomplun, Doreen ^a,b   Schulz, Tim J ^a,b   Müller Schmehl, Katrin ^a   Krause, Anja ^a   Fex, Malin ^c   Puccio, Hélène ^d   Müller, Jörg ^e   Isken, Frank ^a,b   Spranger, Joachim ^a,b   Müller Wieland, Dirk ^f   Magnuson, Mark A ^g   Möhlig, Matthias ^a,b   Koenig, Michel ^d   Pfeiffer, Andreas F H ^a,b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c LUND UNIVERSITY   (Sweden)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^e Magnettech GmbH   (Germany)

^f LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^g VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; INSULIN; REACTIVE OXYGEN METABOLITE; COMPLEMENTARY DNA; IRON BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; GENE DISRUPTION; IMMUNOHISTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY; ALLELE; ANIMAL; C57BL MOUSE; CELL DIVISION; EXON; FLUORESCENCE MICROSCOPY; GENETICS; GENOTYPE; GLUCOSE TOLERANCE TEST; MAGNETISM; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; PHYSIOLOGY; SECRETION; TIME; TISSUE DISTRIBUTION;

ALLELES; ANIMALS; APOPTOSIS; CELL DIVISION; DIABETES MELLITUS; DNA, COMPLEMENTARY; EXONS; GENOTYPE; GLUCOSE TOLERANCE TEST; INSULIN; IRON-BINDING PROTEINS; ISLETS OF LANGERHANS; MAGNETICS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; REACTIVE OXYGEN SPECIES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 85047690706     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI18107     Document Type: Article

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