Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes

Mitochondrion

Volumn 11, Issue 6, 2011, Pages 845-854

  Chowdhury, Subir K Roy ^a   Dobrowsky, Rick T ^b   Fernyhough, Paul ^a,c  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF KANSAS   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

AMPK; Diabetic neuropathy; Dorsal root ganglia; Mitochondrial respiratory chain; PGC 1 ; SIRT

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE BETA; ADENYLATE KINASE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; INSULIN; MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEOME; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE) IRON SULFUR PROTEIN 3; SIRTUIN 1; UNCLASSIFIED DRUG;

AUTOPHAGOSOME; CELL METABOLISM; DEACETYLATION; DIABETES MELLITUS; DIABETIC NEUROPATHY; ENERGY METABOLISM; GENE EXPRESSION; HUMAN; HYPERPOLARIZATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVE DEGENERATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY CHAIN; REVIEW; SENSORY NERVE CELL; SENSORY NEUROPATHY; SPINAL GANGLION;

ANIMALS; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; FOOD; HUMANS; MITOCHONDRIA; NEURONS; PROTEOME; RODENTIA;

RODENTIA;

EID: 82755197943     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2011.06.007     Document Type: Review

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