Molecular targets of a human HNF1α mutation responsible for pancreatic β-cell dysfunction

EMBO Journal

Volumn 19, Issue 16, 2000, Pages 4257-4264

  Wang, Haiyan ^a   Antinozzi, Peter A ^a   Hagenfeldt, Kerstin A ^a   Maechler, Pierre ^a   Wollheim, Claes B ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

cell gene expression; HNF1 ; Insulin secretion; Mitochondrial function; MODY3

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON 14; DNA BINDING PROTEIN; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE TRANSPORTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INSULIN; MESSENGER RNA; MITOCHONDRIAL ENZYME; NUCLEAR FACTOR I; OXOGLUTARATE DEHYDROGENASE; PYRUVATE KINASE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL METABOLISM; CELL SECRETION; CONTROLLED STUDY; GENE INDUCTION; GENE MUTATION; INSULINOMA; MATURITY ONSET DIABETES MELLITUS; MOLECULAR BIOLOGY; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-BACTERIAL AGENTS; BINDING SITES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; DIABETES MELLITUS, TYPE 2; DNA; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXYCYCLINE; FRUCTOSE-BISPHOSPHATE ALDOLASE; GENES, DOMINANT; GLUCOSE TRANSPORTER TYPE 2; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT; IMMUNOBLOTTING; INSULIN; ION CHANNELS; ISLETS OF LANGERHANS; KETOGLUTARATE DEHYDROGENASE COMPLEX; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; NUCLEAR PROTEINS; OXYGEN; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEINS; PYRUVATE KINASE; PYRUVATES; RATS; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

ANIMALIA;

EID: 0034663750     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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