Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase

Nature Communications

Volumn 5, Issue , 2014, Pages

  Kanatsu, Kunihiko ^a   Morohashi, Yuichi ^a,b   Suzuki, Mai ^c   Kuroda, Hiromasa ^a   Watanabe, Toshio ^c   Tomita, Taisuke ^a,b   Iwatsubo, Takeshi ^a,b,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NARA WOMEN'S UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CLATHRIN; CLATHRIN ASSEMBLY PROTEIN; CLATHRIN HEAVY CHAIN; GAMMA SECRETASE; MESNA; SYNAPTOBREVIN; AMYLOID BETA PROTEIN; SECRETASE;

ENZYME ACTIVITY; GENE EXPRESSION; METABOLISM; PEPTIDE; POLYMORPHISM; PROTEIN; STEADY-STATE EQUILIBRIUM;

ANIMAL EXPERIMENT; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; COATED PIT; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME REGULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; STABLE EXPRESSION; STEADY STATE; TRANSIENT EXPRESSION; ANIMAL; FEMALE; GENETICS; HELA CELL LINE; METABOLISM; MUTANT MOUSE STRAIN; PHYSIOLOGY;

AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ENDOCYTOSIS; FEMALE; HELA CELLS; HUMANS; MICE; MICE, MUTANT STRAINS; MONOMERIC CLATHRIN ASSEMBLY PROTEINS;

EID: 84896898403     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4386     Document Type: Article

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