-
1
-
-
84872168596
-
Microglia: scapegoat, saboteur, or something else?
-
Aguzzi A., Barres B.A., Bennett M.L. Microglia: scapegoat, saboteur, or something else?. Science 2013, 339:156-161.
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
2
-
-
34247506244
-
Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system
-
Bell R.D., Sagare A.P., Friedman A.E., Bedi G.S., Holtzman D.M., Deane R., Zlokovic B.V. Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system. J.Cereb. Blood Flow Metab. 2007, 27:909-918.
-
(2007)
J.Cereb. Blood Flow Metab.
, vol.27
, pp. 909-918
-
-
Bell, R.D.1
Sagare, A.P.2
Friedman, A.E.3
Bedi, G.S.4
Holtzman, D.M.5
Deane, R.6
Zlokovic, B.V.7
-
3
-
-
55049142500
-
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE
-
Bertram L., Lange C., Mullin K., Parkinson M., Hsiao M., Hogan M.F., Schjeide B.M., Hooli B., Divito J., Ionita I., et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am. J. Hum. Genet. 2008, 83:623-632.
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 623-632
-
-
Bertram, L.1
Lange, C.2
Mullin, K.3
Parkinson, M.4
Hsiao, M.5
Hogan, M.F.6
Schjeide, B.M.7
Hooli, B.8
Divito, J.9
Ionita, I.10
-
4
-
-
77957927865
-
The genetics of Alzheimer disease: back to the future
-
Bertram L., Lill C.M., Tanzi R.E. The genetics of Alzheimer disease: back to the future. Neuron 2010, 68:270-281.
-
(2010)
Neuron
, vol.68
, pp. 270-281
-
-
Bertram, L.1
Lill, C.M.2
Tanzi, R.E.3
-
5
-
-
0038656361
-
CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice
-
Brinkman-Van der Linden E.C., Angata T., Reynolds S.A., Powell L.D., Hedrick S.M., Varki A. CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice. Mol. Cell. Biol. 2003, 23:4199-4206.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4199-4206
-
-
Brinkman-Van der Linden, E.C.1
Angata, T.2
Reynolds, S.A.3
Powell, L.D.4
Hedrick, S.M.5
Varki, A.6
-
6
-
-
51649118169
-
ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein invitro
-
Chan S.L., Kim W.S., Kwok J.B., Hill A.F., Cappai R., Rye K.A., Garner B. ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein invitro. J.Neurochem. 2008, 106:793-804.
-
(2008)
J.Neurochem.
, vol.106
, pp. 793-804
-
-
Chan, S.L.1
Kim, W.S.2
Kwok, J.B.3
Hill, A.F.4
Cappai, R.5
Rye, K.A.6
Garner, B.7
-
7
-
-
49849085127
-
Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation
-
Choi S.H., Veeraraghavalu K., Lazarov O., Marler S., Ransohoff R.M., Ramirez J.M., Sisodia S.S. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron 2008, 59:568-580.
-
(2008)
Neuron
, vol.59
, pp. 568-580
-
-
Choi, S.H.1
Veeraraghavalu, K.2
Lazarov, O.3
Marler, S.4
Ransohoff, R.M.5
Ramirez, J.M.6
Sisodia, S.S.7
-
9
-
-
84860234082
-
CD33-related siglecs as potential modulators of inflammatory responses
-
Crocker P.R., McMillan S.J., Richards H.E. CD33-related siglecs as potential modulators of inflammatory responses. Ann. N Y Acad. Sci. 2012, 1253:102-111.
-
(2012)
Ann. N Y Acad. Sci.
, vol.1253
, pp. 102-111
-
-
Crocker, P.R.1
McMillan, S.J.2
Richards, H.E.3
-
10
-
-
9144224765
-
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism invivo
-
DeMattos R.B., Cirrito J.R., Parsadanian M., May P.C., O'Dell M.A., Taylor J.W., Harmony J.A., Aronow B.J., Bales K.R., Paul S.M., Holtzman D.M. ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism invivo. Neuron 2004, 41:193-202.
-
(2004)
Neuron
, vol.41
, pp. 193-202
-
-
DeMattos, R.B.1
Cirrito, J.R.2
Parsadanian, M.3
May, P.C.4
O'Dell, M.A.5
Taylor, J.W.6
Harmony, J.A.7
Aronow, B.J.8
Bales, K.R.9
Paul, S.M.10
Holtzman, D.M.11
-
11
-
-
51349085578
-
TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
-
Frank S., Burbach G.J., Bonin M., Walter M., Streit W., Bechmann I., Deller T. TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice. Glia 2008, 56:1438-1447.
-
(2008)
Glia
, vol.56
, pp. 1438-1447
-
-
Frank, S.1
Burbach, G.J.2
Bonin, M.3
Walter, M.4
Streit, W.5
Bechmann, I.6
Deller, T.7
-
12
-
-
68849123079
-
Accumulation of tau induced in neurites by microglial proinflammatory mediators
-
Gorlovoy P., Larionov S., Pham T.T., Neumann H. Accumulation of tau induced in neurites by microglial proinflammatory mediators. FASEB J. 2009, 23:2502-2513.
-
(2009)
FASEB J.
, vol.23
, pp. 2502-2513
-
-
Gorlovoy, P.1
Larionov, S.2
Pham, T.T.3
Neumann, H.4
-
13
-
-
74949127437
-
Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia
-
Grathwohl S.A., Kälin R.E., Bolmont T., Prokop S., Winkelmann G., Kaeser S.A., Odenthal J., Radde R., Eldh T., Gandy S., et al. Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat. Neurosci. 2009, 12:1361-1363.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 1361-1363
-
-
Grathwohl, S.A.1
Kälin, R.E.2
Bolmont, T.3
Prokop, S.4
Winkelmann, G.5
Kaeser, S.A.6
Odenthal, J.7
Radde, R.8
Eldh, T.9
Gandy, S.10
-
14
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Alzheimer Genetic Analysis Group
-
Guerreiro R., Wojtas A., Bras J., Carrasquillo M., Rogaeva E., Majounie E., Cruchaga C., Sassi C., Kauwe J.S., Younkin S., et al. TREM2 variants in Alzheimer's disease. N.Engl. J. Med. 2013, 368:117-127. Alzheimer Genetic Analysis Group.
-
(2013)
N.Engl. J. Med.
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
Cruchaga, C.7
Sassi, C.8
Kauwe, J.S.9
Younkin, S.10
-
15
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
Hardy J.A., Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992, 256:184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
16
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
17
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D., Abraham R., Hollingworth P., Sims R., Gerrish A., Hamshere M.L., Pahwa J.S., Moskvina V., Dowzell K., Williams A., et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat. Genet. 2009, 41:1088-1093.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
Pahwa, J.S.7
Moskvina, V.8
Dowzell, K.9
Williams, A.10
-
18
-
-
84867797446
-
Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide
-
Hashimoto T., Serrano-Pozo A., Hori Y., Adams K.W., Takeda S., Banerji A.O., Mitani A., Joyner D., Thyssen D.H., Bacskai B.J., et al. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide. J.Neurosci. 2012, 32:15181-15192.
-
(2012)
J.Neurosci.
, vol.32
, pp. 15181-15192
-
-
Hashimoto, T.1
Serrano-Pozo, A.2
Hori, Y.3
Adams, K.W.4
Takeda, S.5
Banerji, A.O.6
Mitani, A.7
Joyner, D.8
Thyssen, D.H.9
Bacskai, B.J.10
-
19
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Alzheimer's Disease Neuroimaging Initiative, CHARGE consortiumCHARGE consortium, EADI1 consortiumEADI1 consortium
-
Hollingworth P., Harold D., Sims R., Gerrish A., Lambert J.C., Carrasquillo M.M., Abraham R., Hamshere M.L., Pahwa J.S., Moskvina V., et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 2011, 43:429-435. Alzheimer's Disease Neuroimaging Initiative, CHARGE consortiumCHARGE consortium, EADI1 consortiumEADI1 consortium.
-
(2011)
Nat. Genet.
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
Gerrish, A.4
Lambert, J.C.5
Carrasquillo, M.M.6
Abraham, R.7
Hamshere, M.L.8
Pahwa, J.S.9
Moskvina, V.10
-
20
-
-
40449110688
-
CD33 detection by immunohistochemistry in paraffin-embedded tissues: a new antibody shows excellent specificity and sensitivity for cells of myelomonocytic lineage
-
Hoyer J.D., Grogg K.L., Hanson C.A., Gamez J.D., Dogan A. CD33 detection by immunohistochemistry in paraffin-embedded tissues: a new antibody shows excellent specificity and sensitivity for cells of myelomonocytic lineage. Am. J. Clin. Pathol. 2008, 129:316-323.
-
(2008)
Am. J. Clin. Pathol.
, vol.129
, pp. 316-323
-
-
Hoyer, J.D.1
Grogg, K.L.2
Hanson, C.A.3
Gamez, J.D.4
Dogan, A.5
-
21
-
-
65649114773
-
A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
-
Hsieh C.L., Koike M., Spusta S.C., Niemi E.C., Yenari M., Nakamura M.C., Seaman W.E. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J.Neurochem. 2009, 109:1144-1156.
-
(2009)
J.Neurochem.
, vol.109
, pp. 1144-1156
-
-
Hsieh, C.L.1
Koike, M.2
Spusta, S.C.3
Niemi, E.C.4
Yenari, M.5
Nakamura, M.C.6
Seaman, W.E.7
-
22
-
-
79960371234
-
Targeting siglecs-a novel pharmacological strategy for immuno- and glycotherapy
-
Jandus C., Simon H.U., von Gunten S. Targeting siglecs-a novel pharmacological strategy for immuno- and glycotherapy. Biochem. Pharmacol. 2011, 82:323-332.
-
(2011)
Biochem. Pharmacol.
, vol.82
, pp. 323-332
-
-
Jandus, C.1
Simon, H.U.2
von Gunten, S.3
-
23
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide invivo: evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky J.L., Fadale D.J., Anderson J., Xu G.M., Gonzales V., Jenkins N.A., Copeland N.G., Lee M.K., Younkin L.H., Wagner S.L., et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide invivo: evidence for augmentation of a 42-specific gamma secretase. Hum. Mol. Genet. 2004, 13:159-170.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
-
24
-
-
44649197748
-
ApoE promotes the proteolytic degradation of Abeta
-
Jiang Q., Lee C.Y., Mandrekar S., Wilkinson B., Cramer P., Zelcer N., Mann K., Lamb B., Willson T.M., Collins J.L., et al. ApoE promotes the proteolytic degradation of Abeta. Neuron 2008, 58:681-693.
-
(2008)
Neuron
, vol.58
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
-
25
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson T., Stefansson H., Steinberg S., Jonsdottir I., Jonsson P.V., Snaedal J., Bjornsson S., Huttenlocher J., Levey A.I., Lah J.J., et al. Variant of TREM2 associated with the risk of Alzheimer's disease. N.Engl. J. Med. 2013, 368:107-116.
-
(2013)
N.Engl. J. Med.
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
Bjornsson, S.7
Huttenlocher, J.8
Levey, A.I.9
Lah, J.J.10
-
26
-
-
84859238174
-
What happened to anti-CD33 therapy for acute myeloid leukemia?
-
Jurcic J.G. What happened to anti-CD33 therapy for acute myeloid leukemia?. Curr Hematol Malig Rep 2012, 7:65-73.
-
(2012)
Curr Hematol Malig Rep
, vol.7
, pp. 65-73
-
-
Jurcic, J.G.1
-
27
-
-
84870584668
-
Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains
-
Karch C.M., Jeng A.T., Nowotny P., Cady J., Cruchaga C., Goate A.M. Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains. PLoS ONE 2012, 7:e50976.
-
(2012)
PLoS ONE
, vol.7
-
-
Karch, C.M.1
Jeng, A.T.2
Nowotny, P.3
Cady, J.4
Cruchaga, C.5
Goate, A.M.6
-
29
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
European Alzheimer's Disease Initiative Investigators
-
Lambert J.C., Heath S., Even G., Campion D., Sleegers K., Hiltunen M., Combarros O., Zelenika D., Bullido M.J., Tavernier B., et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat. Genet. 2009, 41:1094-1099. European Alzheimer's Disease Initiative Investigators.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
Combarros, O.7
Zelenika, D.8
Bullido, M.J.9
Tavernier, B.10
-
30
-
-
84862911656
-
Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels
-
Lee C.Y., Tse W., Smith J.D., Landreth G.E. Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels. J.Biol. Chem. 2012, 287:2032-2044.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 2032-2044
-
-
Lee, C.Y.1
Tse, W.2
Smith, J.D.3
Landreth, G.E.4
-
31
-
-
84877311468
-
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
-
Liu C.C., Kanekiyo T., Xu H., Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat. Rev. Neurol. 2013, 9:184.
-
(2013)
Nat. Rev. Neurol.
, vol.9
, pp. 184
-
-
Liu, C.C.1
Kanekiyo, T.2
Xu, H.3
Bu, G.4
-
32
-
-
65249170245
-
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis
-
Mandrekar S., Jiang Q., Lee C.Y., Koenigsknecht-Talboo J., Holtzman D.M., Landreth G.E. Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis. J.Neurosci. 2009, 29:4252-4262.
-
(2009)
J.Neurosci.
, vol.29
, pp. 4252-4262
-
-
Mandrekar, S.1
Jiang, Q.2
Lee, C.Y.3
Koenigsknecht-Talboo, J.4
Holtzman, D.M.5
Landreth, G.E.6
-
33
-
-
77956238665
-
Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease
-
Melchior B., Garcia A.E., Hsiung B.K., Lo K.M., Doose J.M., Thrash J.C., Stalder A.K., Staufenbiel M., Neumann H., Carson M.J. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease. ASN Neuro 2010, 2:e00037.
-
(2010)
ASN Neuro
, vol.2
-
-
Melchior, B.1
Garcia, A.E.2
Hsiung, B.K.3
Lo, K.M.4
Doose, J.M.5
Thrash, J.C.6
Stalder, A.K.7
Staufenbiel, M.8
Neumann, H.9
Carson, M.J.10
-
34
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
-
Naj A.C., Jun G., Beecham G.W., Wang L.S., Vardarajan B.N., Buros J., Gallins P.J., Buxbaum J.D., Jarvik G.P., Crane P.K., et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat. Genet. 2011, 43:436-441.
-
(2011)
Nat. Genet.
, vol.43
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
Wang, L.S.4
Vardarajan, B.N.5
Buros, J.6
Gallins, P.J.7
Buxbaum, J.D.8
Jarvik, G.P.9
Crane, P.K.10
-
35
-
-
65349147691
-
Siglecs as targets for therapy in immune-cell-mediated disease
-
O'Reilly M.K., Paulson J.C. Siglecs as targets for therapy in immune-cell-mediated disease. Trends Pharmacol. Sci. 2009, 30:240-248.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 240-248
-
-
O'Reilly, M.K.1
Paulson, J.C.2
-
36
-
-
84860241831
-
Siglecs as sensors of self in innate and adaptive immune responses
-
Paulson J.C., Macauley M.S., Kawasaki N. Siglecs as sensors of self in innate and adaptive immune responses. Ann. N Y Acad. Sci. 2012, 1253:37-48.
-
(2012)
Ann. N Y Acad. Sci.
, vol.1253
, pp. 37-48
-
-
Paulson, J.C.1
Macauley, M.S.2
Kawasaki, N.3
-
37
-
-
79956129497
-
Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells
-
Pérez-Oliva A.B., Martínez-Esparza M., Vicente-Fernández J.J., Corral-San Miguel R., García-Peñarrubia P., Hernández-Caselles T. Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells. Glycobiology 2011, 21:757-770.
-
(2011)
Glycobiology
, vol.21
, pp. 757-770
-
-
Pérez-Oliva, A.B.1
Martínez-Esparza, M.2
Vicente-Fernández, J.J.3
Corral-San Miguel, R.4
García-Peñarrubia, P.5
Hernández-Caselles, T.6
-
38
-
-
84859400408
-
Siglecs and immune regulation
-
Pillai S., Netravali I.A., Cariappa A., Mattoo H. Siglecs and immune regulation. Annu. Rev. Immunol. 2012, 30:357-392.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 357-392
-
-
Pillai, S.1
Netravali, I.A.2
Cariappa, A.3
Mattoo, H.4
-
39
-
-
80053233055
-
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
-
Prinz M., Priller J., Sisodia S.S., Ransohoff R.M. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat. Neurosci. 2011, 14:1227-1235.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1227-1235
-
-
Prinz, M.1
Priller, J.2
Sisodia, S.S.3
Ransohoff, R.M.4
-
40
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S., Neale B., Todd-Brown K., Thomas L., Ferreira M.A., Bender D., Maller J., Sklar P., de Bakker P.I., Daly M.J., Sham P.C. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 2007, 81:559-575.
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.I.9
Daly, M.J.10
Sham, P.C.11
-
42
-
-
84878458787
-
-
R Development Core Team . R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna. ISBN 3-900051-07-0, .
-
R Development Core Team (2009). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna. ISBN 3-900051-07-0, . http://www.R-project.org.
-
(2009)
-
-
-
43
-
-
0345636018
-
Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model
-
Reilly J.F., Games D., Rydel R.E., Freedman S., Schenk D., Young W.G., Morrison J.H., Bloom F.E. Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model. Proc. Natl. Acad. Sci. USA 2003, 100:4837-4842.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4837-4842
-
-
Reilly, J.F.1
Games, D.2
Rydel, R.E.3
Freedman, S.4
Schenk, D.5
Young, W.G.6
Morrison, J.H.7
Bloom, F.E.8
-
44
-
-
80054113954
-
Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin
-
Ricart A.D. Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin. Clin. Cancer Res. 2011, 17:6417-6427.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6417-6427
-
-
Ricart, A.D.1
-
45
-
-
84860308669
-
The value of immunohistochemistry for CD14, CD123, CD33, myeloperoxidase and CD68R in the diagnosis of acute and chronic myelomonocytic leukaemias
-
Rollins-Raval M.A., Roth C.G. The value of immunohistochemistry for CD14, CD123, CD33, myeloperoxidase and CD68R in the diagnosis of acute and chronic myelomonocytic leukaemias. Histopathology 2012, 60:933-942.
-
(2012)
Histopathology
, vol.60
, pp. 933-942
-
-
Rollins-Raval, M.A.1
Roth, C.G.2
-
46
-
-
84866456583
-
Preventing Alzheimer's disease
-
Selkoe D.J. Preventing Alzheimer's disease. Science 2012, 337:1488-1492.
-
(2012)
Science
, vol.337
, pp. 1488-1492
-
-
Selkoe, D.J.1
-
47
-
-
80052837439
-
Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease
-
Serrano-Pozo A., Mielke M.L., Gomez-Isla T., Betensky R.A., Growdon J.H., Frosch M.P., Hyman B.T. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. Am. J. Pathol. 2011, 179:1373-1384.
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 1373-1384
-
-
Serrano-Pozo, A.1
Mielke, M.L.2
Gomez-Isla, T.3
Betensky, R.A.4
Growdon, J.H.5
Frosch, M.P.6
Hyman, B.T.7
-
48
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
CHARGE Consortium, GERAD1 ConsortiumGERAD1 Consortium, EADI1 ConsortiumEADI1 Consortium
-
Seshadri S., Fitzpatrick A.L., Ikram M.A., DeStefano A.L., Gudnason V., Boada M., Bis J.C., Smith A.V., Carassquillo M.M., Lambert J.C., et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010, 303:1832-1840. CHARGE Consortium, GERAD1 ConsortiumGERAD1 Consortium, EADI1 ConsortiumEADI1 Consortium.
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
DeStefano, A.L.4
Gudnason, V.5
Boada, M.6
Bis, J.C.7
Smith, A.V.8
Carassquillo, M.M.9
Lambert, J.C.10
-
50
-
-
84872574316
-
A brief history of Alzheimer's disease gene discovery
-
Tanzi R.E. A brief history of Alzheimer's disease gene discovery. J.Alzheimers Dis. 2013, 33(Suppl 1):S5-S13.
-
(2013)
J.Alzheimers Dis.
, vol.33
, Issue.SUPPL 1
-
-
Tanzi, R.E.1
-
51
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective
-
Tanzi R.E., Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005, 120:545-555.
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
52
-
-
82755197062
-
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast
-
Treusch S., Hamamichi S., Goodman J.L., Matlack K.E., Chung C.Y., Baru V., Shulman J.M., Parrado A., Bevis B.J., Valastyan J.S., et al. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science 2011, 334:1241-1245.
-
(2011)
Science
, vol.334
, pp. 1241-1245
-
-
Treusch, S.1
Hamamichi, S.2
Goodman, J.L.3
Matlack, K.E.4
Chung, C.Y.5
Baru, V.6
Shulman, J.M.7
Parrado, A.8
Bevis, B.J.9
Valastyan, J.S.10
-
53
-
-
56549099820
-
Basic and clinical immunology of Siglecs
-
von Gunten S., Bochner B.S. Basic and clinical immunology of Siglecs. Ann. N Y Acad. Sci. 2008, 1143:61-82.
-
(2008)
Ann. N Y Acad. Sci.
, vol.1143
, pp. 61-82
-
-
von Gunten, S.1
Bochner, B.S.2
-
54
-
-
38149122249
-
Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor
-
Walter R.B., Häusermann P., Raden B.W., Teckchandani A.M., Kamikura D.M., Bernstein I.D., Cooper J.A. Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor. Traffic 2008, 9:267-279.
-
(2008)
Traffic
, vol.9
, pp. 267-279
-
-
Walter, R.B.1
Häusermann, P.2
Raden, B.W.3
Teckchandani, A.M.4
Kamikura, D.M.5
Bernstein, I.D.6
Cooper, J.A.7
-
55
-
-
79951538920
-
P75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain
-
Wang Y.J., Wang X., Lu J.J., Li Q.X., Gao C.Y., Liu X.H., Sun Y., Yang M., Lim Y., Evin G., et al. p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain. J.Neurosci. 2011, 31:2292-2304.
-
(2011)
J.Neurosci.
, vol.31
, pp. 2292-2304
-
-
Wang, Y.J.1
Wang, X.2
Lu, J.J.3
Li, Q.X.4
Gao, C.Y.5
Liu, X.H.6
Sun, Y.7
Yang, M.8
Lim, Y.9
Evin, G.10
-
56
-
-
84862270067
-
Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis
-
Xiao Q., Gil S.C., Yan P., Wang Y., Han S., Gonzales E., Perez R., Cirrito J.R., Lee J.M. Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis. J.Biol. Chem. 2012, 287:21279-21289.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 21279-21289
-
-
Xiao, Q.1
Gil, S.C.2
Yan, P.3
Wang, Y.4
Han, S.5
Gonzales, E.6
Perez, R.7
Cirrito, J.R.8
Lee, J.M.9
-
57
-
-
34547823043
-
The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures
-
Yerbury J.J., Poon S., Meehan S., Thompson B., Kumita J.R., Dobson C.M., Wilson M.R. The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures. FASEB J. 2007, 21:2312-2322.
-
(2007)
FASEB J.
, vol.21
, pp. 2312-2322
-
-
Yerbury, J.J.1
Poon, S.2
Meehan, S.3
Thompson, B.4
Kumita, J.R.5
Dobson, C.M.6
Wilson, M.R.7
|