메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Brd4 and HEXIM1: Multiple roles in P-TEFb regulation and cancer

Author keywords

[No Author keywords available]

Indexed keywords

BROMODOMAIN CONTAINING PROTEIN 4; CYCLIN D1; CYCLIN T1; DOXORUBICIN; ESTROGEN RECEPTOR ALPHA; ETOPOSIDE; FLAVOPIRIDOL; HEXAMETHYLENE BISACETAMIDE INDUCIBLE PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; NUCLEOPHOSMIN; NUTLIN 3; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN 14 3 3; PROTEIN MDM2; PROTEIN P53; REGULATOR PROTEIN; ROSCOVITINE; SCAFFOLD PROTEIN; SMALL NUCLEAR RNA; TAMOXIFEN; TAMOXIFEN CITRATE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 84896808244     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/232870     Document Type: Review
Times cited : (61)

References (129)
  • 1
    • 0029011873 scopus 로고
    • Purification of P-TEFb, a transcription factor required for the transition into productive elongation
    • 2-s2.0-0029011873 10.1074/jbc.270.21.12335
    • Marshall N. F., Price D. H., Purification of P-TEFb, a transcription factor required for the transition into productive elongation. The Journal of Biological Chemistry 1995 270 21 12335 12338 2-s2.0-0029011873 10.1074/jbc.270.21.12335
    • (1995) The Journal of Biological Chemistry , vol.270 , Issue.21 , pp. 12335-12338
    • Marshall, N.F.1    Price, D.H.2
  • 3
    • 0032534814 scopus 로고    scopus 로고
    • Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro
    • 2-s2.0-0032534814 10.1093/emboj/17.24.7395
    • Wada T., Takagi T., Yamaguchi Y., Watanabe D., Handa H., Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro. The EMBO Journal 1998 17 24 7395 7403 2-s2.0-0032534814 10.1093/emboj/17.24.7395
    • (1998) The EMBO Journal , vol.17 , Issue.24 , pp. 7395-7403
    • Wada, T.1    Takagi, T.2    Yamaguchi, Y.3    Watanabe, D.4    Handa, H.5
  • 4
    • 0033515521 scopus 로고    scopus 로고
    • NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
    • 2-s2.0-0033515521
    • Yamaguchi Y., Takagi T., Wada T., Yano K., Furuya A., Sugimoto S., Hasegawa J., Handa H., NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 1999 97 1 41 51 2-s2.0-0033515521
    • (1999) Cell , vol.97 , Issue.1 , pp. 41-51
    • Yamaguchi, Y.1    Takagi, T.2    Wada, T.3    Yano, K.4    Furuya, A.5    Sugimoto, S.6    Hasegawa, J.7    Handa, H.8
  • 6
    • 0346095303 scopus 로고    scopus 로고
    • Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element
    • 2-s2.0-0346095303 10.1128/MCB.24.2.787-795.2004
    • Fujinaga K., Irwin D., Huang Y., Taube R., Kurosu T., Peterlin B. M., Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element. Molecular and Cellular Biology 2004 24 2 787 795 2-s2.0-0346095303 10.1128/MCB.24.2.787-795.2004
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.2 , pp. 787-795
    • Fujinaga, K.1    Irwin, D.2    Huang, Y.3    Taube, R.4    Kurosu, T.5    Peterlin, B.M.6
  • 7
    • 0342748478 scopus 로고    scopus 로고
    • Domains in the SPT5 protein that modulate its transcriptional regulatory properties
    • 2-s2.0-0342748478 10.1128/MCB.20.9.2970-2983.2000
    • Ivanov D., Kwak Y. T., Guo J., Gaynor R. B., Domains in the SPT5 protein that modulate its transcriptional regulatory properties. Molecular and Cellular Biology 2000 20 9 2970 2983 2-s2.0-0342748478 10.1128/MCB.20.9.2970-2983.2000
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.9 , pp. 2970-2983
    • Ivanov, D.1    Kwak, Y.T.2    Guo, J.3    Gaynor, R.B.4
  • 8
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • 2-s2.0-67649648237 10.1016/j.cell.2009.05.047
    • Hargreaves D. C., Horng T., Medzhitov R., Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 2009 138 1 129 145 2-s2.0-67649648237 10.1016/j.cell.2009.05.047
    • (2009) Cell , vol.138 , Issue.1 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 9
    • 70149112313 scopus 로고    scopus 로고
    • Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation
    • 2-s2.0-70149112313 10.1016/j.cell.2009.07.031
    • Zippo A., Serafini R., Rocchigiani M., Pennacchini S., Krepelova A., Oliviero S., Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation. Cell 2009 138 6 1122 1136 2-s2.0-70149112313 10.1016/j.cell.2009.07.031
    • (2009) Cell , vol.138 , Issue.6 , pp. 1122-1136
    • Zippo, A.1    Serafini, R.2    Rocchigiani, M.3    Pennacchini, S.4    Krepelova, A.5    Oliviero, S.6
  • 11
    • 0035943710 scopus 로고    scopus 로고
    • Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
    • 2-s2.0-0035943710 10.1074/jbc.M102306200
    • Chao S.-H., Price D. H., Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. The Journal of Biological Chemistry 2001 276 34 31793 31799 2-s2.0-0035943710 10.1074/jbc.M102306200
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.34 , pp. 31793-31799
    • Chao, S.-H.1    Price, D.H.2
  • 12
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • 2-s2.0-34447098370 10.1016/j.cell.2007.05.042
    • Guenther M. G., Levine S. S., Boyer L. A., Jaenisch R., Young R. A., A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007 130 1 77 88 2-s2.0-34447098370 10.1016/j.cell.2007.05.042
    • (2007) Cell , vol.130 , Issue.1 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 13
    • 36549013619 scopus 로고    scopus 로고
    • RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
    • 2-s2.0-36549013619 10.1038/ng.2007.26
    • Zeitlinger J., Stark A., Kellis M., Hong J.-W., Nechaev S., Adelman K., Levine M., Young R. A., RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nature Genetics 2007 39 12 1512 1516 2-s2.0-36549013619 10.1038/ng.2007.26
    • (2007) Nature Genetics , vol.39 , Issue.12 , pp. 1512-1516
    • Zeitlinger, J.1    Stark, A.2    Kellis, M.3    Hong, J.-W.4    Nechaev, S.5    Adelman, K.6    Levine, M.7    Young, R.A.8
  • 15
    • 84874175008 scopus 로고    scopus 로고
    • Precise maps of RNA polymerase reveal how promoters direct initiation and pausing
    • Kwak H., Fuda N. J., Core L. J., Lis J. T., Precise maps of RNA polymerase reveal how promoters direct initiation and pausing. Science 2013 339 6122 950 953
    • (2013) Science , vol.339 , Issue.6122 , pp. 950-953
    • Kwak, H.1    Fuda, N.J.2    Core, L.J.3    Lis, J.T.4
  • 17
    • 0024414213 scopus 로고
    • HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
    • 2-s2.0-0024414213
    • Laspia M. F., Rice A. P., Mathews M. B., HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation. Cell 1989 59 2 283 292 2-s2.0-0024414213
    • (1989) Cell , vol.59 , Issue.2 , pp. 283-292
    • Laspia, M.F.1    Rice, A.P.2    Mathews, M.B.3
  • 18
    • 0033102387 scopus 로고    scopus 로고
    • Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b
    • 2-s2.0-0033102387 10.1006/viro.1998.9589
    • Wimmer J., Fujinaga K., Taube R., Cujec T. P., Zhu Y., Peng J., Price D. H., Peterlin B. M., Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b. Virology 1999 255 1 182 189 2-s2.0-0033102387 10.1006/viro.1998.9589
    • (1999) Virology , vol.255 , Issue.1 , pp. 182-189
    • Wimmer, J.1    Fujinaga, K.2    Taube, R.3    Cujec, T.P.4    Zhu, Y.5    Peng, J.6    Price, D.H.7    Peterlin, B.M.8
  • 19
    • 0032533253 scopus 로고    scopus 로고
    • The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein
    • 2-s2.0-0032533253
    • Garber M. E., Wei P., KewalRamani V. N., Mayall T. P., Herrmann C. H., Rice A. P., Littman D. R., Jones K. A., The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes and Development 1998 12 22 3512 3527 2-s2.0-0032533253
    • (1998) Genes and Development , vol.12 , Issue.22 , pp. 3512-3527
    • Garber, M.E.1    Wei, P.2    Kewalramani, V.N.3    Mayall, T.P.4    Herrmann, C.H.5    Rice, A.P.6    Littman, D.R.7    Jones, K.A.8
  • 20
    • 0033053040 scopus 로고    scopus 로고
    • Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription
    • 2-s2.0-0033053040 10.1073/pnas.96.6.2728
    • Chen D., Fong Y., Zhou Q., Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription. Proceedings of the National Academy of Sciences of the United States of America 1999 96 6 2728 2733 2-s2.0-0033053040 10.1073/pnas.96.6.2728
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.6 , pp. 2728-2733
    • Chen, D.1    Fong, Y.2    Zhou, Q.3
  • 21
    • 0032577577 scopus 로고    scopus 로고
    • Identification of a cyclin subunit required for the function of Drosophila P-TEFb
    • 2-s2.0-0032577577 10.1074/jbc.273.22.13855
    • Peng J., Marshall N. F., Price D. H., Identification of a cyclin subunit required for the function of Drosophila P-TEFb. The Journal of Biological Chemistry 1998 273 22 13855 13860 2-s2.0-0032577577 10.1074/jbc.273.22.13855
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.22 , pp. 13855-13860
    • Peng, J.1    Marshall, N.F.2    Price, D.H.3
  • 22
    • 0032548918 scopus 로고    scopus 로고
    • A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
    • 2-s2.0-0032548918 10.1016/S0092-8674(00)80939-3
    • Wei P., Garber M. E., Fang S.-M., Fischer W. H., Jones K. A., A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 1998 92 4 451 462 2-s2.0-0032548918 10.1016/S0092-8674(00)80939-3
    • (1998) Cell , vol.92 , Issue.4 , pp. 451-462
    • Wei, P.1    Garber, M.E.2    Fang, S.-M.3    Fischer, W.H.4    Jones, K.A.5
  • 23
    • 0037102566 scopus 로고    scopus 로고
    • CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C elegans embryo
    • 2-s2.0-0037102566 10.1101/gad.999002
    • Shim E. Y., Walker A. K., Shi Y., Blackwell T. K., CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo. Genes and Development 2002 16 16 2135 2146 2-s2.0-0037102566 10.1101/gad.999002
    • (2002) Genes and Development , vol.16 , Issue.16 , pp. 2135-2146
    • Shim, E.Y.1    Walker, A.K.2    Shi, Y.3    Blackwell, T.K.4
  • 24
    • 1642441939 scopus 로고    scopus 로고
    • Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes
    • 2-s2.0-1642441939 10.1016/S1097-2765(03)00526-4
    • Ni Z., Schwartz B. E., Werner J., Suarez J.-R., Lis J. T., Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. Molecular Cell 2004 13 1 55 65 2-s2.0-1642441939 10.1016/S1097-2765(03)00526-4
    • (2004) Molecular Cell , vol.13 , Issue.1 , pp. 55-65
    • Ni, Z.1    Schwartz, B.E.2    Werner, J.3    Suarez, J.-R.4    Lis, J.T.5
  • 25
    • 77958587420 scopus 로고    scopus 로고
    • CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
    • 2-s2.0-77958587420 10.1101/gad.1968210
    • Bartkowiak B., Liu P., Phatnani H. P., Fuda N. J., Cooper J. J., Price D. H., Adelman K., Lis J. T., Greenleaf A. L., CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes and Development 2010 24 20 2303 2316 2-s2.0-77958587420 10.1101/gad.1968210
    • (2010) Genes and Development , vol.24 , Issue.20 , pp. 2303-2316
    • Bartkowiak, B.1    Liu, P.2    Phatnani, H.P.3    Fuda, N.J.4    Cooper, J.J.5    Price, D.H.6    Adelman, K.7    Lis, J.T.8    Greenleaf, A.L.9
  • 26
    • 0037468903 scopus 로고    scopus 로고
    • Identification of a novel isoform of Cdk9
    • 2-s2.0-0037468903 10.1016/S0378-1119(03)00466-9
    • Shore S. M., Byers S. A., Maury W., Price D. H., Identification of a novel isoform of Cdk9. Gene 2003 307 1-2 175 182 2-s2.0-0037468903 10.1016/S0378-1119(03)00466-9
    • (2003) Gene , vol.307 , Issue.1-2 , pp. 175-182
    • Shore, S.M.1    Byers, S.A.2    Maury, W.3    Price, D.H.4
  • 27
    • 0032031706 scopus 로고    scopus 로고
    • Identification of multiple cyclin subunits of human P-TEFb
    • 2-s2.0-0032031706
    • Peng J., Zhu Y., Milton J. T., Price D. H., Identification of multiple cyclin subunits of human P-TEFb. Genes and Development 1998 12 5 755 762 2-s2.0-0032031706
    • (1998) Genes and Development , vol.12 , Issue.5 , pp. 755-762
    • Peng, J.1    Zhu, Y.2    Milton, J.T.3    Price, D.H.4
  • 28
    • 0033521094 scopus 로고    scopus 로고
    • Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription
    • 2-s2.0-0033521094 10.1074/jbc.274.49.34527
    • Fu T.-J., Peng J., Lee G., Price D. H., Flores O., Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription. The Journal of Biological Chemistry 1999 274 49 34527 34530 2-s2.0-0033521094 10.1074/jbc.274.49.34527
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.49 , pp. 34527-34530
    • Fu, T.-J.1    Peng, J.2    Lee, G.3    Price, D.H.4    Flores, O.5
  • 29
    • 0242361319 scopus 로고    scopus 로고
    • Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA
    • 2-s2.0-0242361319 10.1016/S1097-2765(03)00388-5
    • Yik J. H. N., Chen R., Nishimura R., Jennings J. L., Link A. J., Zhou Q., Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Molecular Cell 2003 12 4 971 982 2-s2.0-0242361319 10.1016/S1097-2765(03)00388-5
    • (2003) Molecular Cell , vol.12 , Issue.4 , pp. 971-982
    • Yik, J.H.N.1    Chen, R.2    Nishimura, R.3    Jennings, J.L.4    Link, A.J.5    Zhou, Q.6
  • 30
    • 0038111978 scopus 로고    scopus 로고
    • MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner
    • 2-s2.0-0038111978 10.1128/MCB.23.14.4859-4869.2003
    • Michels A. A., Nguyen V. T., Fraldi A., Labas V., Edwards M., Bonnet F., Lania L., Bensaude O., MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. Molecular and Cellular Biology 2003 23 14 4859 4869 2-s2.0-0038111978 10.1128/MCB.23.14.4859-4869.2003
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.14 , pp. 4859-4869
    • Michels, A.A.1    Nguyen, V.T.2    Fraldi, A.3    Labas, V.4    Edwards, M.5    Bonnet, F.6    Lania, L.7    Bensaude, O.8
  • 34
    • 29244474416 scopus 로고    scopus 로고
    • Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb
    • 2-s2.0-29244474416 10.1038/sj.emboj.7600883
    • Barboric M., Kohoutek J., Price J. P., Blazek D., Price D. H., Peterlin B. M., Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb. The EMBO Journal 2005 24 24 4291 4303 2-s2.0-29244474416 10.1038/sj.emboj.7600883
    • (2005) The EMBO Journal , vol.24 , Issue.24 , pp. 4291-4303
    • Barboric, M.1    Kohoutek, J.2    Price, J.P.3    Blazek, D.4    Price, D.H.5    Peterlin, B.M.6
  • 35
    • 23744467035 scopus 로고    scopus 로고
    • Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
    • 2-s2.0-23744467035 10.1016/j.molcel.2005.06.029
    • Yang Z., Yik J. H. N., Chen R., He N., Moon K. J., Ozato K., Zhou Q., Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Molecular Cell 2005 19 4 535 545 2-s2.0-23744467035 10.1016/j.molcel.2005.06.029
    • (2005) Molecular Cell , vol.19 , Issue.4 , pp. 535-545
    • Yang, Z.1    Yik, J.H.N.2    Chen, R.3    He, N.4    Moon, K.J.5    Ozato, K.6    Zhou, Q.7
  • 36
    • 23744514308 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
    • 2-s2.0-23744514308 10.1016/j.molcel.2005.06.027
    • Jang M. K., Mochizuki K., Zhou M., Jeong H.-S., Brady J. N., Ozato K., The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Molecular Cell 2005 19 4 523 534 2-s2.0-23744514308 10.1016/j.molcel.2005.06.027
    • (2005) Molecular Cell , vol.19 , Issue.4 , pp. 523-534
    • Jang, M.K.1    Mochizuki, K.2    Zhou, M.3    Jeong, H.-S.4    Brady, J.N.5    Ozato, K.6
  • 37
    • 33749234198 scopus 로고    scopus 로고
    • The Yin and Yang of P-TEFb regulation: Implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation
    • 2-s2.0-33749234198 10.1128/MMBR.00011-06
    • Zhou Q., Yik J. H. N., The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation. Microbiology and Molecular Biology Reviews 2006 70 3 646 659 2-s2.0-33749234198 10.1128/MMBR.00011-06
    • (2006) Microbiology and Molecular Biology Reviews , vol.70 , Issue.3 , pp. 646-659
    • Zhou, Q.1    Yik, J.H.N.2
  • 38
    • 34548219126 scopus 로고    scopus 로고
    • HEXIM1 and the control of transcription elongation: From cancer and inflammation to AIDS and cardiac hypertrophy
    • 2-s2.0-34548219126
    • Dey A., Chao S.-H., Lane D. P., HEXIM1 and the control of transcription elongation: from cancer and inflammation to AIDS and cardiac hypertrophy. Cell Cycle 2007 6 15 1856 1863 2-s2.0-34548219126
    • (2007) Cell Cycle , vol.6 , Issue.15 , pp. 1856-1863
    • Dey, A.1    Chao, S.-H.2    Lane, D.P.3
  • 39
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • 2-s2.0-0034610814 10.1038/47412
    • Strahl B. D., Allis C. D., The language of covalent histone modifications. Nature 2000 403 6765 41 45 2-s2.0-0034610814 10.1038/47412
    • (2000) Nature , vol.403 , Issue.6765 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 40
    • 70149105669 scopus 로고    scopus 로고
    • The role of human bromodomains in chromatin biology and gene transcription
    • 2-s2.0-70149105669
    • Sanchez R., Zhou M.-M., The role of human bromodomains in chromatin biology and gene transcription. Current Opinion in Drug Discovery and Development 2009 12 5 659 665 2-s2.0-70149105669
    • (2009) Current Opinion in Drug Discovery and Development , vol.12 , Issue.5 , pp. 659-665
    • Sanchez, R.1    Zhou, M.-M.2
  • 43
    • 77956392623 scopus 로고    scopus 로고
    • Brd4 engagement from chromatin targeting to transcriptional regulation: Selective contact with acetylated histone H3 and H4
    • Chiang C. M., Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4. F1000 Biology Reports 2009 1 98
    • (2009) F1000 Biology Reports , vol.1 , pp. 98
    • Chiang, C.M.1
  • 44
    • 79959483607 scopus 로고    scopus 로고
    • The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3
    • 2-s2.0-79959483607 10.1128/MCB.01341-10
    • Rahman S., Sowa M. E., Ottinger M., Smith J. A., Shi Y., Harper J. W., Howley P. M., The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Molecular and Cellular Biology 2011 31 13 2641 2652 2-s2.0-79959483607 10.1128/MCB.01341-10
    • (2011) Molecular and Cellular Biology , vol.31 , Issue.13 , pp. 2641-2652
    • Rahman, S.1    Sowa, M.E.2    Ottinger, M.3    Smith, J.A.4    Shi, Y.5    Harper, J.W.6    Howley, P.M.7
  • 46
  • 47
    • 42049095157 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 stimulates g1 gene transcription and promotes progression to S phase
    • 2-s2.0-42049095157 10.1074/jbc.M707603200
    • Mochizuki K., Nishiyama A., Jang M. K., Dey A., Ghosh A., Tamura T., Natsume H., Yao H., Ozato K., The bromodomain protein Brd4 stimulates g1 gene transcription and promotes progression to S phase. The Journal of Biological Chemistry 2008 283 14 9040 9048 2-s2.0-42049095157 10.1074/jbc.M707603200
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.14 , pp. 9040-9048
    • Mochizuki, K.1    Nishiyama, A.2    Jang, M.K.3    Dey, A.4    Ghosh, A.5    Tamura, T.6    Natsume, H.7    Yao, H.8    Ozato, K.9
  • 48
    • 38549113034 scopus 로고    scopus 로고
    • Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G 1 gene expression and cell cycle progression
    • 2-s2.0-38549113034 10.1128/MCB.01020-07
    • Yang Z., He N., Zhou Q., Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G 1 gene expression and cell cycle progression. Molecular and Cellular Biology 2008 28 3 967 976 2-s2.0-38549113034 10.1128/MCB.01020-07
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.3 , pp. 967-976
    • Yang, Z.1    He, N.2    Zhou, Q.3
  • 49
    • 73949087197 scopus 로고    scopus 로고
    • Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription
    • 2-s2.0-73949087197 10.1091/mbc.E09-05-0380
    • Dey A., Nishiyama A., Karpova T., McNally J., Ozato K., Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription. Molecular Biology of the Cell 2009 20 23 4899 4909 2-s2.0-73949087197 10.1091/mbc.E09-05- 0380
    • (2009) Molecular Biology of the Cell , vol.20 , Issue.23 , pp. 4899-4909
    • Dey, A.1    Nishiyama, A.2    Karpova, T.3    McNally, J.4    Ozato, K.5
  • 50
    • 80455122751 scopus 로고    scopus 로고
    • Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation
    • 2-s2.0-80455122751 10.1038/ncb2341
    • Zhao R., Nakamura T., Fu Y., Lazar Z., Spector D. L., Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nature Cell Biology 2011 13 11 1295 1304 2-s2.0-80455122751 10.1038/ncb2341
    • (2011) Nature Cell Biology , vol.13 , Issue.11 , pp. 1295-1304
    • Zhao, R.1    Nakamura, T.2    Fu, Y.3    Lazar, Z.4    Spector, D.L.5
  • 51
    • 84872174424 scopus 로고    scopus 로고
    • Two faces of BRD4: Mitotic bookmark and transcriptional lynchpin
    • Devaiah B. N., Singer D. S., Two faces of BRD4: mitotic bookmark and transcriptional lynchpin. Transcription 2012 4 1 13 17
    • (2012) Transcription , vol.4 , Issue.1 , pp. 13-17
    • Devaiah, B.N.1    Singer, D.S.2
  • 52
    • 82255175234 scopus 로고    scopus 로고
    • BRD4 jump-starts transcription after mitotic silencing
    • ARTICLE 133 2-s2.0-82255175234 10.1186/gb-2011-12-11-133
    • Voigt P., Reinberg D., BRD4 jump-starts transcription after mitotic silencing. Genome Biology 2011 12 11, article 133 2-s2.0-82255175234 10.1186/gb-2011-12-11-133
    • (2011) Genome Biology , vol.12 , Issue.11
    • Voigt, P.1    Reinberg, D.2
  • 53
    • 84859479811 scopus 로고    scopus 로고
    • Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure
    • 2-s2.0-84859479811 10.1074/jbc.M111.323493
    • Wang R., Li Q., Helfer C. M., Jiao J., You J., Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure. The Journal of Biological Chemistry 2012 287 14 10738 10752 2-s2.0-84859479811 10.1074/jbc.M111.323493
    • (2012) The Journal of Biological Chemistry , vol.287 , Issue.14 , pp. 10738-10752
    • Wang, R.1    Li, Q.2    Helfer, C.M.3    Jiao, J.4    You, J.5
  • 54
    • 2042468820 scopus 로고    scopus 로고
    • Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes
    • 2-s2.0-2042468820 10.1016/S0092-8674(04)00402-7
    • You J., Croyle J. L., Nishimura A., Ozato K., Howley P. M., Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 2004 117 3 349 360 2-s2.0-2042468820 10.1016/S0092-8674(04)00402-7
    • (2004) Cell , vol.117 , Issue.3 , pp. 349-360
    • You, J.1    Croyle, J.L.2    Nishimura, A.3    Ozato, K.4    Howley, P.M.5
  • 56
    • 78650566210 scopus 로고    scopus 로고
    • Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation
    • 2-s2.0-78650566210 10.1016/j.bbagrm.2010.11.001
    • Nechaev S., Adelman K., Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elongation. Biochimica et Biophysica Acta 2011 1809 1 34 45 2-s2.0-78650566210 10.1016/j.bbagrm.2010.11.001
    • (2011) Biochimica et Biophysica Acta , vol.1809 , Issue.1 , pp. 34-45
    • Nechaev, S.1    Adelman, K.2
  • 58
    • 84889026690 scopus 로고    scopus 로고
    • RNA polymerase II transcription elongation control
    • Guo J., Price D. H., RNA polymerase II transcription elongation control. Chemical Reviews 2013 113 11 8583 8603
    • (2013) Chemical Reviews , vol.113 , Issue.11 , pp. 8583-8603
    • Guo, J.1    Price, D.H.2
  • 59
    • 66449089824 scopus 로고    scopus 로고
    • 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor
    • 2-s2.0-66449089824 10.4161/rna.6.2.8115
    • Diribarne G., Bensaude O., 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor. RNA Biology 2009 6 2 122 128 2-s2.0-66449089824 10.4161/rna.6.2.8115
    • (2009) RNA Biology , vol.6 , Issue.2 , pp. 122-128
    • Diribarne, G.1    Bensaude, O.2
  • 60
    • 77449119756 scopus 로고    scopus 로고
    • A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP
    • 2-s2.0-77449119756 10.1093/nar/gkp977
    • Xue Y., Yang Z., Chen R., Zhou Q., A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP. Nucleic Acids Research 2009 38 2 360 369 2-s2.0-77449119756 10.1093/nar/gkp977
    • (2009) Nucleic Acids Research , vol.38 , Issue.2 , pp. 360-369
    • Xue, Y.1    Yang, Z.2    Chen, R.3    Zhou, Q.4
  • 61
    • 44149117974 scopus 로고    scopus 로고
    • PP2B and PP1 α cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling
    • 2-s2.0-44149117974 10.1101/gad.1636008
    • Chen R., Liu M., Li H., Xue Y., Ramey W. N., He N., Ai N., Luo H., Zhu Y., Zhou N., Zhou Q., PP2B and PP1 α cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. Genes and Development 2008 22 10 1356 1368 2-s2.0-44149117974 10.1101/gad.1636008
    • (2008) Genes and Development , vol.22 , Issue.10 , pp. 1356-1368
    • Chen, R.1    Liu, M.2    Li, H.3    Xue, Y.4    Ramey, W.N.5    He, N.6    Ai, N.7    Luo, H.8    Zhu, Y.9    Zhou, N.10    Zhou, Q.11
  • 62
    • 36048945927 scopus 로고    scopus 로고
    • HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription
    • 2-s2.0-36048945927 10.1371/journal.ppat.0030146
    • Contreras X., Barboric M., Lenasi T., Peterlin B. M., HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription. PLoS Pathogens 2007 3 10 1459 1469 2-s2.0-36048945927 10.1371/journal.ppat. 0030146
    • (2007) PLoS Pathogens , vol.3 , Issue.10 , pp. 1459-1469
    • Contreras, X.1    Barboric, M.2    Lenasi, T.3    Peterlin, B.M.4
  • 64
    • 83755220044 scopus 로고    scopus 로고
    • Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation
    • 2-s2.0-83755220044 10.1093/nar/gkr698
    • Ai N., Hu X., Ding F., Yu B., Wang H., Lu X., Zhang K., Li Y., Han A., Lin W., Liu R., Chen R., Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation. Nucleic Acids Research 2011 39 22 9592 9604 2-s2.0-83755220044 10.1093/nar/gkr698
    • (2011) Nucleic Acids Research , vol.39 , Issue.22 , pp. 9592-9604
    • Ai, N.1    Hu, X.2    Ding, F.3    Yu, B.4    Wang, H.5    Lu, X.6    Zhang, K.7    Li, Y.8    Han, A.9    Lin, W.10    Liu, R.11    Chen, R.12
  • 68
    • 84874582225 scopus 로고    scopus 로고
    • A new BET on the control of HIV latency
    • Karn J., A new BET on the control of HIV latency. Cell Cycle 2013 12 4 545 546
    • (2013) Cell Cycle , vol.12 , Issue.4 , pp. 545-546
    • Karn, J.1
  • 69
    • 58149487612 scopus 로고    scopus 로고
    • Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29
    • 2-s2.0-58149487612 10.1128/JVI.01316-08
    • Zhou M., Huang K., Jung K.-J., Cho W.-K., Klase Z., Kashanchi F., Pise-Masison C. A., Brady J. N., Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29. Journal of Virology 2009 83 2 1036 1044 2-s2.0-58149487612 10.1128/JVI.01316-08
    • (2009) Journal of Virology , vol.83 , Issue.2 , pp. 1036-1044
    • Zhou, M.1    Huang, K.2    Jung, K.-J.3    Cho, W.-K.4    Klase, Z.5    Kashanchi, F.6    Pise-Masison, C.A.7    Brady, J.N.8
  • 70
    • 78651469063 scopus 로고    scopus 로고
    • Isolation and functional characterization of P-TEFb-associated factors that control general and HIV-1 transcriptional elongation
    • 2-s2.0-78651469063 10.1016/j.ymeth.2010.04.005
    • Chen R., Liu M., Zhang K., Zhou Q., Isolation and functional characterization of P-TEFb-associated factors that control general and HIV-1 transcriptional elongation. Methods 2011 53 1 85 90 2-s2.0-78651469063 10.1016/j.ymeth.2010.04.005
    • (2011) Methods , vol.53 , Issue.1 , pp. 85-90
    • Chen, R.1    Liu, M.2    Zhang, K.3    Zhou, Q.4
  • 72
    • 61749088806 scopus 로고    scopus 로고
    • Brd4 coactivates transcriptional activation of NF- B via specific binding to acetylated RelA
    • 2-s2.0-61749088806 10.1128/MCB.01365-08
    • Huang B., Yang X.-D., Zhou M.-M., Ozato K., Chen L.-F., Brd4 coactivates transcriptional activation of NF- B via specific binding to acetylated RelA. Molecular and Cellular Biology 2009 29 5 1375 1387 2-s2.0-61749088806 10.1128/MCB.01365-08
    • (2009) Molecular and Cellular Biology , vol.29 , Issue.5 , pp. 1375-1387
    • Huang, B.1    Yang, X.-D.2    Zhou, M.-M.3    Ozato, K.4    Chen, L.-F.5
  • 76
    • 84885776400 scopus 로고    scopus 로고
    • Brd4 shields chromatin from ATM kinase signaling storms
    • Choi S., Bakkenist C. J., Brd4 shields chromatin from ATM kinase signaling storms. Science Signaling 2013 6 293 pe30
    • (2013) Science Signaling , vol.6 , Issue.293
    • Choi, S.1    Bakkenist, C.J.2
  • 78
    • 84862738480 scopus 로고    scopus 로고
    • BET domain co-regulators in obesity, inflammation and cancer
    • Belkina A. C., Denis G. V., BET domain co-regulators in obesity, inflammation and cancer. Nature Reviews Cancer 2012 12 7 465 477
    • (2012) Nature Reviews Cancer , vol.12 , Issue.7 , pp. 465-477
    • Belkina, A.C.1    Denis, G.V.2
  • 81
    • 84862306532 scopus 로고    scopus 로고
    • NUT midline carcinoma: An imaging case series and review of literature
    • 2-s2.0-80054873409 10.1007/s00247-011-2272-3
    • Polsani A., Braithwaite K. A., Alazraki A. L., Abramowsky C., Shehata B. M., NUT midline carcinoma: an imaging case series and review of literature. Pediatric Radiology 2012 42 2 205 210 2-s2.0-80054873409 10.1007/s00247-011- 2272-3
    • (2012) Pediatric Radiology , vol.42 , Issue.2 , pp. 205-210
    • Polsani, A.1    Braithwaite, K.A.2    Alazraki, A.L.3    Abramowsky, C.4    Shehata, B.M.5
  • 82
    • 84856857218 scopus 로고    scopus 로고
    • Pathogenesis of NUT midline carcinoma
    • 2-s2.0-84856857218 10.1146/annurev-pathol-011811-132438
    • French C. A., Pathogenesis of NUT midline carcinoma. Annual Review of Pathology 2012 7 247 265 2-s2.0-84856857218 10.1146/annurev-pathol-011811-132438
    • (2012) Annual Review of Pathology , vol.7 , pp. 247-265
    • French, C.A.1
  • 83
    • 78049425945 scopus 로고    scopus 로고
    • NUT midline carcinoma
    • 2-s2.0-78049425945
    • French C. A., NUT midline carcinoma. Cancer Genetics and Cytogenetics 2010 203 1 16 20 2-s2.0-78049425945
    • (2010) Cancer Genetics and Cytogenetics , vol.203 , Issue.1 , pp. 16-20
    • French, C.A.1
  • 84
    • 84861627221 scopus 로고    scopus 로고
    • Bromodomain-Containing protein 4: A dynamic regulator of breast cancer metastasis through modulation of the extracellular matrix
    • 670632 10.1155/2012/670632
    • Alsarraj J., Hunter K. W., Bromodomain-Containing protein 4: a dynamic regulator of breast cancer metastasis through modulation of the extracellular matrix. International Journal of Breast Cancer 2012 2012 7 670632 10.1155/2012/670632
    • (2012) International Journal of Breast Cancer , vol.2012 , pp. 7
    • Alsarraj, J.1    Hunter, K.W.2
  • 85
    • 79954603178 scopus 로고    scopus 로고
    • Deletion of the proline-rich region of the murine metastasis susceptibility gene Brd4 promotes epithelial-to-mesenchymal transition- and stem cell-like conversion
    • 2-s2.0-79954603178 10.1158/0008-5472.CAN-10-4417
    • Alsarraj J., Walker R. C., Webster J. D., Geiger T. R., Crawford N. P. S., Simpson R. M., Ozato K., Hunter K. W., Deletion of the proline-rich region of the murine metastasis susceptibility gene Brd4 promotes epithelial-to- mesenchymal transition- and stem cell-like conversion. Cancer Research 2011 71 8 3121 3131 2-s2.0-79954603178 10.1158/0008-5472.CAN-10-4417
    • (2011) Cancer Research , vol.71 , Issue.8 , pp. 3121-3131
    • Alsarraj, J.1    Walker, R.C.2    Webster, J.D.3    Geiger, T.R.4    Crawford, N.P.S.5    Simpson, R.M.6    Ozato, K.7    Hunter, K.W.8
  • 86
    • 84899927814 scopus 로고    scopus 로고
    • Brd4 maintains constitutively active NF-kappaB in cancer cells by binding to acetylated RelA
    • 10.1038/onc.2013.179
    • Zou Z., Huang B., Wu X., Zhang H., Qi J., Bradner J., Nair S., Chen L. F., Brd4 maintains constitutively active NF-kappaB in cancer cells by binding to acetylated RelA. Oncogene 2013 10.1038/onc.2013.179
    • (2013) Oncogene
    • Zou, Z.1    Huang, B.2    Wu, X.3    Zhang, H.4    Qi, J.5    Bradner, J.6    Nair, S.7    Chen, L.F.8
  • 87
    • 80052595172 scopus 로고    scopus 로고
    • Short hairpin RNA screen reveals bromodomain proteins as novel targets in acute myeloid leukemia
    • 2-s2.0-80052595172 10.1016/j.ccr.2011.08.019
    • Blobel G. A., Kalota A., Sanchez P. V., Carroll M., Short hairpin RNA screen reveals bromodomain proteins as novel targets in acute myeloid leukemia. Cancer Cell 2011 20 3 287 288 2-s2.0-80052595172 10.1016/j.ccr.2011.08.019
    • (2011) Cancer Cell , vol.20 , Issue.3 , pp. 287-288
    • Blobel, G.A.1    Kalota, A.2    Sanchez, P.V.3    Carroll, M.4
  • 95
    • 85052488824 scopus 로고    scopus 로고
    • When are the BET factors the most sensitive to bromodomain inhibitors?
    • Khochbin S., When are the BET factors the most sensitive to bromodomain inhibitors? Transcription 2013 4 2 54 57
    • (2013) Transcription , vol.4 , Issue.2 , pp. 54-57
    • Khochbin, S.1
  • 96
    • 83255192184 scopus 로고    scopus 로고
    • A peek into the complex realm of histone phosphorylation
    • 2-s2.0-83255192184 10.1128/MCB.05631-11
    • Banerjee T., Chakravarti D., A peek into the complex realm of histone phosphorylation. Molecular and Cellular Biology 2011 31 24 4858 4873 2-s2.0-83255192184 10.1128/MCB.05631-11
    • (2011) Molecular and Cellular Biology , vol.31 , Issue.24 , pp. 4858-4873
    • Banerjee, T.1    Chakravarti, D.2
  • 97
    • 1642326716 scopus 로고    scopus 로고
    • Phosphorylation of histone H3: A balancing act between chromosome condensation and transcriptional activation
    • 2-s2.0-1642326716 10.1016/j.tig.2004.02.007
    • Nowak S. J., Corces V. G., Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends in Genetics 2004 20 4 214 220 2-s2.0-1642326716 10.1016/j.tig.2004.02.007
    • (2004) Trends in Genetics , vol.20 , Issue.4 , pp. 214-220
    • Nowak, S.J.1    Corces, V.G.2
  • 98
    • 84867183192 scopus 로고    scopus 로고
    • Histone phosphorylation: A chromatin modification involved in diverse nuclear events
    • Rossetto D., Avvakumov N., Cote J., Histone phosphorylation: a chromatin modification involved in diverse nuclear events. Epigenetics 2012 7 10 1098 1108
    • (2012) Epigenetics , vol.7 , Issue.10 , pp. 1098-1108
    • Rossetto, D.1    Avvakumov, N.2    Cote, J.3
  • 99
    • 84867399880 scopus 로고    scopus 로고
    • Histone H3 phosphorylation - A versatile chromatin modification for different occasions
    • Sawicka A., Seiser C., Histone H3 phosphorylation-a versatile chromatin modification for different occasions. Biochimie 2012 94 11 2193 2201
    • (2012) Biochimie , vol.94 , Issue.11 , pp. 2193-2201
    • Sawicka, A.1    Seiser, C.2
  • 100
    • 0025872683 scopus 로고
    • Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors
    • 2-s2.0-0025872683
    • Mahadevan L. C., Willis A. C., Barratt M. J., Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors. Cell 1991 65 5 775 783 2-s2.0-0025872683
    • (1991) Cell , vol.65 , Issue.5 , pp. 775-783
    • Mahadevan, L.C.1    Willis, A.C.2    Barratt, M.J.3
  • 102
    • 0033120663 scopus 로고    scopus 로고
    • Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis
    • 2-s2.0-0033120663 10.1006/dbio.1998.9180
    • Ghatpande S., Goswami S., Mathew S., Rong G., Cai L., Shafiq S., Siddiqui M. A. Q., Identification of a novel cardiac lineage-associated protein(cCLP-1): a candidate regulator of cardiogenesis. Developmental Biology 1999 208 1 210 221 2-s2.0-0033120663 10.1006/dbio.1998.9180
    • (1999) Developmental Biology , vol.208 , Issue.1 , pp. 210-221
    • Ghatpande, S.1    Goswami, S.2    Mathew, S.3    Rong, G.4    Cai, L.5    Shafiq, S.6    Siddiqui, M.A.Q.7
  • 104
    • 0042014234 scopus 로고    scopus 로고
    • Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors
    • 2-s2.0-0042014234
    • Wittmann B. M., Wang N., Montano M. M., Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors. Cancer Research 2003 63 16 5151 5158 2-s2.0-0042014234
    • (2003) Cancer Research , vol.63 , Issue.16 , pp. 5151-5158
    • Wittmann, B.M.1    Wang, N.2    Montano, M.M.3
  • 105
    • 0035903160 scopus 로고    scopus 로고
    • Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements
    • 2-s2.0-0035903160 10.1074/jbc.M103339200
    • Castro-Rivera E., Samudio I., Safe S., Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements. The Journal of Biological Chemistry 2001 276 33 30853 30861 2-s2.0-0035903160 10.1074/jbc.M103339200
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.33 , pp. 30853-30861
    • Castro-Rivera, E.1    Samudio, I.2    Safe, S.3
  • 106
    • 0033637703 scopus 로고    scopus 로고
    • Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
    • 2-s2.0-0033637703
    • Shang Y., Hu X., DiRenzo J., Lazar M. A., Brown M., Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 2000 103 6 843 852 2-s2.0-0033637703
    • (2000) Cell , vol.103 , Issue.6 , pp. 843-852
    • Shang, Y.1    Hu, X.2    Direnzo, J.3    Lazar, M.A.4    Brown, M.5
  • 107
    • 0034485142 scopus 로고    scopus 로고
    • Estrogen receptor alpha in human breast cancer: Occurrence and significance
    • 2-s2.0-0034485142 10.1023/A:1009594727358
    • Ali S., Coombes R. C., Estrogen receptor alpha in human breast cancer: occurrence and significance. Journal of Mammary Gland Biology and Neoplasia 2000 5 3 271 281 2-s2.0-0034485142 10.1023/A:1009594727358
    • (2000) Journal of Mammary Gland Biology and Neoplasia , vol.5 , Issue.3 , pp. 271-281
    • Ali, S.1    Coombes, R.C.2
  • 108
    • 2142652244 scopus 로고    scopus 로고
    • Therapeutic targeting in the estrogen receptor hormonal pathway
    • 2-s2.0-2142652244
    • Katzenellenbogen B. S., Frasor J., Therapeutic Targeting in the Estrogen Receptor Hormonal Pathway. Seminars in Oncology 2004 31 1, supplement 3 28 38 2-s2.0-2142652244
    • (2004) Seminars in Oncology , vol.31 , Issue.1 SUPPL. 3 , pp. 28-38
    • Katzenellenbogen, B.S.1    Frasor, J.2
  • 109
    • 24644486087 scopus 로고    scopus 로고
    • The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1
    • 2-s2.0-24644486087 10.1038/sj.onc.1208728
    • Wittmann B. M., Fujinaga K., Deng H., Ogba N., Montano M. M., The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1. Oncogene 2005 24 36 5576 5588 2-s2.0-24644486087 10.1038/sj.onc.1208728
    • (2005) Oncogene , vol.24 , Issue.36 , pp. 5576-5588
    • Wittmann, B.M.1    Fujinaga, K.2    Deng, H.3    Ogba, N.4    Montano, M.M.5
  • 110
    • 33747347877 scopus 로고    scopus 로고
    • Treatment of postmenopausal breast cancer with selective estrogen receptor modulators (SERMs)
    • 2-s2.0-33747347877
    • Lewis-Wambi J. S., Jordan V. C., Treatment of postmenopausal breast cancer with selective estrogen receptor modulators (SERMs). Breast Disease 2005 24 1 93 105 2-s2.0-33747347877
    • (2005) Breast Disease , vol.24 , Issue.1 , pp. 93-105
    • Lewis-Wambi, J.S.1    Jordan, V.C.2
  • 111
    • 80051796258 scopus 로고    scopus 로고
    • HEXIM1 is a critical determinant of the response to tamoxifen
    • 2-s2.0-80051796258 10.1038/onc.2011.76
    • Ketchart W., Ogba N., Kresak A., Albert J. M., Pink J. J., Montano M. M., HEXIM1 is a critical determinant of the response to tamoxifen. Oncogene 2011 30 33 3563 3569 2-s2.0-80051796258 10.1038/onc.2011.76
    • (2011) Oncogene , vol.30 , Issue.33 , pp. 3563-3569
    • Ketchart, W.1    Ogba, N.2    Kresak, A.3    Albert, J.M.4    Pink, J.J.5    Montano, M.M.6
  • 112
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • 2-s2.0-0037699954 10.1038/nm0603-669
    • Ferrara N., Gerber H.-P., LeCouter J., The biology of VEGF and its receptors. Nature Medicine 2003 9 6 669 676 2-s2.0-0037699954 10.1038/nm0603-669
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 669-676
    • Ferrara, N.1    Gerber, H.-P.2    Lecouter, J.3
  • 113
    • 77954087427 scopus 로고    scopus 로고
    • HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland
    • 2-s2.0-77954087427 10.1038/onc.2010.110
    • Ogba N., Doughman Y. Q., Chaplin L. J., Hu Y., Gargesha M., Watanabe M., Montano M. M., HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland. Oncogene 2010 29 25 3639 3649 2-s2.0-77954087427 10.1038/onc.2010.110
    • (2010) Oncogene , vol.29 , Issue.25 , pp. 3639-3649
    • Ogba, N.1    Doughman, Y.Q.2    Chaplin, L.J.3    Hu, Y.4    Gargesha, M.5    Watanabe, M.6    Montano, M.M.7
  • 115
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • 2-s2.0-0036984640
    • Folkman J., Role of angiogenesis in tumor growth and metastasis. Seminars in Oncology 2002 29 6, supplement 16 15 18 2-s2.0-0036984640
    • (2002) Seminars in Oncology , vol.29 , Issue.6 SUPPL. 16 , pp. 15-18
    • Folkman, J.1
  • 118
    • 0036302062 scopus 로고    scopus 로고
    • Nucleophosmin regulates the stability and transcriptional activity of p53
    • 2-s2.0-0036302062 10.1038/ncb814
    • Colombo E., Marine J.-C., Danovi D., Falini B., Pelicci P. G., Nucleophosmin regulates the stability and transcriptional activity of p53. Nature Cell Biology 2002 4 7 529 533 2-s2.0-0036302062 10.1038/ncb814
    • (2002) Nature Cell Biology , vol.4 , Issue.7 , pp. 529-533
    • Colombo, E.1    Marine, J.-C.2    Danovi, D.3    Falini, B.4    Pelicci, P.G.5
  • 120
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19(ARF)
    • 2-s2.0-0030728468
    • Kamijo T., Zindy F., Roussel M. F., Quelle D. E., Downing J. R., Ashmun R. A., Grosveld G., Sherr C. J., Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19(ARF). Cell 1997 91 5 649 659 2-s2.0-0030728468
    • (1997) Cell , vol.91 , Issue.5 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3    Quelle, D.E.4    Downing, J.R.5    Ashmun, R.A.6    Grosveld, G.7    Sherr, C.J.8
  • 121
    • 2342491487 scopus 로고    scopus 로고
    • Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation
    • 2-s2.0-2342491487 10.1016/S1535-6108(04)00110-2
    • Kurki S., Peltonen K., Latonen L., Kiviharju T. M., Ojala P. M., Meek D., Laiho M., Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation. Cancer Cell 2004 5 5 465 475 2-s2.0-2342491487 10.1016/S1535-6108(04)00110-2
    • (2004) Cancer Cell , vol.5 , Issue.5 , pp. 465-475
    • Kurki, S.1    Peltonen, K.2    Latonen, L.3    Kiviharju, T.M.4    Ojala, P.M.5    Meek, D.6    Laiho, M.7
  • 124
    • 79959223906 scopus 로고    scopus 로고
    • NPMc+ AML cell line shows differential protein expression and lower sensitivity to DNA-damaging and p53-inducing anti-cancer compounds
    • 2-s2.0-79959223906 10.4161/cc.10.12.15859
    • Lew Q. J., Tan C. H., Gurumurthy M., Chu K. L., Cheong N., Lane D. P., Chao S.-H., NPMc+ AML cell line shows differential protein expression and lower sensitivity to DNA-damaging and p53-inducing anti-cancer compounds. Cell Cycle 2011 10 12 1978 1987 2-s2.0-79959223906 10.4161/cc.10.12.15859
    • (2011) Cell Cycle , vol.10 , Issue.12 , pp. 1978-1987
    • Lew, Q.J.1    Tan, C.H.2    Gurumurthy, M.3    Chu, K.L.4    Cheong, N.5    Lane, D.P.6    Chao, S.-H.7
  • 125
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • 2-s2.0-0030941458 10.1016/S0092-8674(00)81871-1
    • Levine A. J., p53, the cellular gatekeeper for growth and division. Cell 1997 88 3 323 331 2-s2.0-0030941458 10.1016/S0092-8674(00)81871-1
    • (1997) Cell , vol.88 , Issue.3 , pp. 323-331
    • Levine, A.J.1
  • 126
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • 2-s2.0-0031583962 10.1016/S0014-5793(97)01480-4
    • Honda R., Tanaka H., Yasuda H., Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Letters 1997 420 1 25 27 2-s2.0-0031583962 10.1016/S0014-5793(97)01480-4
    • (1997) FEBS Letters , vol.420 , Issue.1 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 127
    • 0033767235 scopus 로고    scopus 로고
    • Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome- mediated degradation
    • 2-s2.0-0033767235 10.1128/MCB.20.22.8458-8467.2000
    • Rodriguez M. S., Desterro J. M. P., Lain S., Lane D. P., Hay R. T., Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation. Molecular and Cellular Biology 2000 20 22 8458 8467 2-s2.0-0033767235 10.1128/MCB.20.22.8458-8467.2000
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.22 , pp. 8458-8467
    • Rodriguez, M.S.1    Desterro, J.M.P.2    Lain, S.3    Lane, D.P.4    Hay, R.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.