HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

PLoS Pathogens

Volumn 3, Issue 10, 2007, Pages 1459-1469

  Contreras, Xavier ^a   Barboric, Matjaz ^a   Lenasi, Tina ^a   Peterlin, B Matija ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HEXAMETHYLENEBISACETAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN HEXIM1; PROTEIN KINASE B; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG; ACETAMIDE DERIVATIVE; AKT1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; HEXIM1 PROTEIN, HUMAN; RNA BINDING PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN;

APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERSISTENT VIRUS INFECTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; TRANSCRIPTION INITIATION; VIROGENESIS; VIRUS GENOME; VIRUS TRANSCRIPTION; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETAMIDES; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, VIRAL; HIV-1; HUMANS; JURKAT CELLS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTO-ONCOGENE PROTEINS C-AKT; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA-BINDING PROTEINS;

EID: 36048945927     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030146     Document Type: Article

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