Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition

Journal of Biological Chemistry

Volumn 287, Issue 34, 2012, Pages 28840-28851

  Zhang, Guangtao ^a   Liu, Ruijie ^a,b   Zhong, Yifei ^c   Plotnikov, Alexander N ^a   Zhang, Weijia ^a   Zeng, Lei ^a   Rusinova, Elena ^a   Gerona Nevarro, Guillermo ^a   Moshkina, Natasha ^a   Joshua, Jennifer ^a   Chuang, Peter Y ^a   Ohlmeyer, Michael ^a   He, John Cijiang ^a,b   Zhou, Ming Ming ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION MOLECULES; ANIMAL MODEL; CHEMOKINES; CHRONIC KIDNEY DISEASE; COFACTORS; CYTOKINES; DOWN-REGULATION; END STAGE RENAL DISEASE; HIV INFECTION; KIDNEY CELLS; KIDNEY DISEASE; NEPHROPATHY; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROINFLAMMATORY; RNA POLYMERASE II; SELECTIVE INHIBITION; SMALL MOLECULES; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL COMPLEXES; TRANSGENIC MICE;

DISEASES; GENES; MOLECULES; RNA; TRANSCRIPTION;

PATHOLOGY;

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MS 417; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN BRD4; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KIDNEY DISEASE; KIDNEY INJURY; MALE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

ACYLATION; AIDS-ASSOCIATED NEPHROPATHY; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HIV-1; HUMANS; MICE; MICE, TRANSGENIC; NF-KAPPA B; NUCLEAR PROTEINS; RNA POLYMERASE II; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84865222098     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.359505     Document Type: Article

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