NPMc+ AML cell line shows differential protein expression and lower sensitivity to DNA-damaging and p53-inducing anti-cancer compounds

Cell Cycle

Volumn 10, Issue 12, 2011, Pages 1978-1987

  Lew, Qiao Jing ^a   Tan, Chuan Hao ^a   Gurumurthy, Meera ^a   Chu, Kai Ling ^a   Cheong, Nge ^a   Lane, David P ^b   Chao, Sheng Hao ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

Author keywords

Acute myeloid leukemia; CYC202; Doxorubicin; Etoposide; Flavopiridol; HEXIM1; Nucleophosmin; Nutlin 3; P TEFb; p53

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CASPASE 7; CASPASE 9; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; CYCLOHEXIMIDE; DNA; DOXORUBICIN; ETOPOSIDE; FLAVOPIRIDOL; HEXAMETHYLENE BISACETAMIDE INDUCIBLE PROTEIN 1; MESSENGER RNA; NUCLEAR PROTEIN; NUCLEOPHOSMIN; NUTLIN 3; PROTEIN MDM2; PROTEIN NOXA; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; REPRESSOR PROTEIN; RNA POLYMERASE II; ROSCOVITINE; SURVIVIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL MUTANT; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

EID: 79959223906     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.12.15859     Document Type: Article

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