NUT midline carcinoma: An imaging case series and review of literature

Pediatric Radiology

Volumn 42, Issue 2, 2012, Pages 205-210

  Polsani, Aruna ^a   Braithwaite, Kiery A ^a   Alazraki, Adina L ^a   Abramowsky, Carlos ^a   Shehata, Bahig M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Children; Imaging; NUT midline carcinoma; Radiology

Indexed keywords

ARTICLE; CARCINOMA; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; IMAGING; KARYOTYPING; MALE; MEDICAL RECORD REVIEW; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUT MIDLINE CARCINOMA; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; ADOLESCENT; DIFFERENTIAL DIAGNOSIS; FATALITY; FEMALE; INFANT; KARYOTYPE; LIVER TUMOR; ORBIT TUMOR; REVIEW; THIGH;

CONTRAST MEDIUM; DIAGNOSTIC AGENT; NUCLEAR PROTEIN; NUT PROTEIN, HUMAN; ONCOPROTEIN;

ADOLESCENT; CARCINOMA; CONTRAST MEDIA; DIAGNOSIS, DIFFERENTIAL; FATAL OUTCOME; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; INFANT, NEWBORN; KARYOTYPE; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; NUCLEAR PROTEINS; ONCOGENE PROTEINS; ORBITAL NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RETROSPECTIVE STUDIES; THIGH; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84862306532     PISSN: 03010449     EISSN: 14321998     Source Type: Journal    
DOI: 10.1007/s00247-011-2272-3     Document Type: Article

References (13)

1. Shehata BM, Steelman CK, Abramowsky CR et al (2009) NUT midline carcinoma in a newborn with multiorgan disseminated tumor and a 2-year-old with a pancreatic/hepatic primary. Pediatr Dev Pathol 13:481-485
2. French CA (2010) NUT midline carcinoma. Cancer Genet Cytogenet 203:16-20
3. Kubonishi I, Takehara N, Iwata J et al (1991) Novel t(15;19)(q15; p13) chromosomal abnormality in a thymic carcinoma. Cancer Res 51:3327-3328
4. French CA, Kutok JL, Faquin WC et al (2004) Midline carcinoma of children and young adults with NUT rearrangement. J Clin Oncol 22:4135-4139 (Pubitemid 41185183)
5. Stelow EB, French CA (2009) Carcinomas of the upper aerodigestive tract with rearrangement of the nuclear protein of the testis (NUT) gene (NUT midline carcinomas). Adv Anat Pathol 16:92-96
6. French CA (2010) Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol 63:492-496
7. Teo MY, Crotty P, O'Sullivan M et al (2011) NUT midline carcinoma in a young woman. J Clin Oncol 29:336-339
8. Nelson BA, Lee EY, French CA et al (2010) BRD4-NUT carcinoma of the mediastinum in a pediatric patient: Multidetector computed tomography imaging findings. J Thorac Imaging 25:9-96
9. Mertens F, Wiebe T, Alfdercreutz C et al (2007) Successful treatment of a child with t(15;19)-positive tumor. Pediatr Blood Cancer 49:1015-1017 (Pubitemid 350022467)
10. Rahbar R, Vargas SO, Miyamoto CR et al (2003) The role of chromosomal translocation (15;19) in the carcinoma of the upper aerodigestive tract in children. Otolaryngol Head Neck Surg 129:698-704 (Pubitemid 37509770)
11. Schwartz ES, Mathias HD, Lemieux ME et al (2011) Differentiation of NUT midline carcinoma by epigenomic reprogramming. Cancer Res 71:2686-2696
12. Fujioka N, French CA, Cameron MJ et al (2010) Long-term survival of a patient with squamous cell carcinoma harboring NUT gene rearrangement. J Thorac Oncol 5:1704-1705
13. Zhu B, Laskin W, French CA et al (2011) NUT midline carcinoma: A neoplasm with diagnostic challenges in cytology. Cytopathology. doi:10.1111/j.1365-2303. 2010.00838.x