BET proteins promote efficient murine leukemia virus integration at transcription start sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 29, 2013, Pages 12036-12041

  Sharma, Amit ^a   Larue, Ross C ^a   Plumb, Matthew R ^a   Malani, Nirav ^a   Male, Frances ^a   Slaughter, Alison ^a   Kessl, Jacques J ^a   Shkriabai, Nikolozi ^a   Coward, Elizabeth ^a   Aiyer, Sriram S ^b   Green, Patrick L ^a,c   Wu, Li ^a,c   Roth, Monica J ^b   Bushman, Frederic D ^a   Kvaratskhelia, Mamuka ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Retroviral Gene Therapy; Virus Host Interactions

Indexed keywords

BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN BRD2; BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN BRD3; BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN BRD4; CELL PROTEIN; HISTONE; INTEGRASE; RECOMBINANT PROTEIN; RETROVIRUS VECTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RNA INTERFERENCE; TRANSCRIPTION INITIATION SITE; VIRAL GENE THERAPY; VIRUS CELL INTERACTION; VIRUS DNA CELL DNA INTERACTION;

RETROVIRAL GENE THERAPY; VIRUS-HOST INTERACTIONS;

ANIMALS; AZEPINES; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; HEK293 CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOST-PATHOGEN INTERACTIONS; HUMANS; INTEGRASES; LEUKEMIA VIRUS, MURINE; MASS SPECTROMETRY; MICE; NIH 3T3 CELLS; NUCLEAR PROTEINS; PROTEOMICS; RECOMBINANT PROTEINS; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRIAZOLES; VIRUS INTEGRATION;

EID: 84880392326     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1307157110     Document Type: Article

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