Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo

Journal of Biological Chemistry

Volumn 276, Issue 34, 2001, Pages 31793-31799

  Chao, Sheng Hao ^a   Price, David H ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOASSAY; ENZYME INHIBITION; IMMUNOLOGY; ONCOLOGY; RNA; VIRUSES;

PHOSPHORYLATION;

BIOCHEMISTRY;

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; CYCLIN DEPENDENT KINASE 9; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN T1; ELONGATION FACTOR; ELONGATION FACTOR P TEFB; FLAVOPIRIDOL; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RNA POLYMERASE II; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; ENZYME INHIBITOR; FLAVONOID; PIPERIDINE DERIVATIVE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CANCER; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IC 50; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STOICHIOMETRY; TRANSACTIVATION; TRANSCRIPTION REGULATION; VIRUS REPLICATION; ANIMAL; DROSOPHILA; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PROTEIN BINDING;

HUMAN IMMUNODEFICIENCY VIRUS; UNIDENTIFIED BACULOVIRUS;

ANIMALS; DROSOPHILA; ENZYME INHIBITORS; FLAVONOIDS; PIPERIDINES; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

EID: 0035943710     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102306200     Document Type: Article

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