-
1
-
-
79952321571
-
NUTmidline carcinoma in a newborn with multiorgan disseminated tumor and a 2-year-old with a pancreatic/hepatic primary
-
Shehata BM, Steelman CK, Abramowsky CR, Olson TA, French CA, et al. 2009.NUTmidline carcinoma in a newborn with multiorgan disseminated tumor and a 2-year-old with a pancreatic/hepatic primary. Pediatr. Dev. Pathol. 13:481-85
-
(2009)
Pediatr. Dev. Pathol
, vol.13
, pp. 481-85
-
-
Shehata, B.M.1
Steelman, C.K.2
Abramowsky, C.R.3
Olson, T.A.4
French, C.A.5
-
2
-
-
46249117863
-
NUT rearrangement in undifferentiated carcinomas of the upper aerodigestive tract
-
Stelow EB, Bellizzi AM, Taneja K, Mills SE, Legallo RD, et al. 2008. NUT rearrangement in undifferentiated carcinomas of the upper aerodigestive tract. Am. J. Surg. Pathol. 32:828-34
-
(2008)
Am. J. Surg. Pathol
, vol.32
, pp. 828-34
-
-
Stelow, E.B.1
Bellizzi, A.M.2
Taneja, K.3
Mills, S.E.4
Legallo, R.D.5
-
3
-
-
7044245866
-
Midline carcinoma of children and young adults with NUT rearrangement
-
DOI 10.1200/JCO.2004.02.107
-
French CA, Kutok JL, Faquin WC, Toretsky JA, Antonescu CR, et al. 2004. Midline carcinoma of children and young adults with NUT rearrangement. J. Clin. Oncol. 22:4135-39 (Pubitemid 41185183)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.20
, pp. 4135-4139
-
-
French, C.A.1
Kutok, J.L.2
Faquin, W.C.3
Toretsky, J.A.4
Antonescu, C.R.5
Griffin, C.A.6
Nose, V.7
Vargas, S.O.8
Moschovi, M.9
Tzortzatou-Stathopoulou, F.10
Miyoshi, I.11
Perez-Atayde, A.R.12
Aster, J.C.13
Fletcher, J.A.14
-
4
-
-
77953714098
-
Demystified molecular pathology of NUT midline carcinomas
-
French CA. 2010. Demystified molecular pathology of NUT midline carcinomas. J. Clin. Pathol. 63:492-96
-
(2010)
J. Clin. Pathol.
, vol.63
, pp. 492-96
-
-
French, C.A.1
-
5
-
-
68249091362
-
NUT midline carcinoma of the parotid gland with mesenchymal diffentiation
-
den Bakker MA, Beverloo BH, van den Heuvel-Eibrink MM, Meeuwis CA, Tan LM, et al. 2009. NUT midline carcinoma of the parotid gland with mesenchymal diffentiation. Am. J. Surg. Pathol. 33:1253-58
-
(2009)
Am. J. Surg. Pathol
, vol.33
, pp. 1253-58
-
-
Den Bakker, M.A.1
Beverloo, B.H.2
Van Den Heuvel-Eibrink, M.M.3
Meeuwis, C.A.4
Tan, L.M.5
-
6
-
-
77953082858
-
NUT gene rearrangement in a poorly differentiated carcinoma of the submandibular gland
-
Ziai J, French CA, Zambrano E. 2010. NUT gene rearrangement in a poorly differentiated carcinoma of the submandibular gland. Head Neck Pathol. 4:163-68
-
(2010)
Head Neck Pathol.
, vol.4
, pp. 163-68
-
-
Ziai, J.1
French, C.A.2
Zambrano, E.3
-
7
-
-
35648989427
-
Successful treatment of a child with t(15;19)-positive tumor
-
DOI 10.1002/pbc.20755
-
Mertens F, Wiebe T, Adlercreutz C, Mandahl N, French CA. 2007. Successful treatment of a child with t(15;19)-positive tumor. Pediatr. Blood Cancer 49:1015-17 (Pubitemid 350022467)
-
(2007)
Pediatric Blood and Cancer
, vol.49
, Issue.7
, pp. 1015-1017
-
-
Mertens, F.1
Wiebe, T.2
Adlercreutz, C.3
Mandahl, N.4
French, C.A.5
-
8
-
-
33646251400
-
Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy
-
Engleson J, Soller M, Panagopoulos I, Dahlen A, Dictor M, Jerkeman M. 2006. Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy. BMC Cancer 6:69
-
(2006)
BMC Cancer
, vol.6
, pp. 69
-
-
Engleson, J.1
Soller, M.2
Panagopoulos, I.3
Dahlen, A.4
Dictor, M.5
Jerkeman, M.6
-
9
-
-
77953462791
-
Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1
-
Liebertz DJ, Lechner MG, Masood R, Sinha UK, Han J, et al. 2010. Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1. Head Neck Oncol. 2:5
-
(2010)
Head Neck Oncol.
, vol.2
, pp. 5
-
-
Liebertz, D.J.1
Lechner, M.G.2
Masood, R.3
Sinha, U.K.4
Han, J.5
-
10
-
-
33845311843
-
Human cancers express a mutator phenotype
-
DOI 10.1073/pnas.0607057103
-
Bielas JH, Loeb KR, Rubin BP, True LD, Loeb LA. 2006. Human cancers express a mutator phenotype. Proc. Natl. Acad. Sci. USA 103:18238-42 (Pubitemid 44871642)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.48
, pp. 18238-18242
-
-
Bielas, J.H.1
Loeb, K.R.2
Rubin, B.P.3
True, L.D.4
Loeb, L.A.5
-
11
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE. 1997. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopietic cell. Nat. Med. 3:730-37 (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
12
-
-
24644480749
-
Molecular requirements for epithelial-mesenchymal transition during tumor progression
-
DOI 10.1016/j.ceb.2005.08.001, PII S0955067405001043
-
HuberMA, KrautN, BeugH. 2005. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr. Opin. Cell Biol. 17:548-58 (Pubitemid 41267170)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.SPEC. ISS. 5
, pp. 548-558
-
-
Huber, M.A.1
Kraut, N.2
Beug, H.3
-
13
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
DOI 10.1038/nrm1835, PII NRM1835
-
Thiery JP, Sleeman JP. 2006. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7:131-42 (Pubitemid 43278296)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.2
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
14
-
-
77956394108
-
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
-
Reynoird N, Schwartz BE, Delvecchio M, Sadoul K, Meyers D, et al. 2010. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J. 29:2943-52
-
(2010)
EMBO J.
, vol.29
, pp. 2943-52
-
-
Reynoird, N.1
Schwartz, B.E.2
Delvecchio, M.3
Sadoul, K.4
Meyers, D.5
-
15
-
-
0037439788
-
BRD4-NUT fusion oncogene: A novel mechanism in aggressive carcinoma
-
French CA, Miyoshi I, Kubonishi I, Grier HE, Perez-Atayde AR, Fletcher JA. 2003. BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma. Cancer Res. 63:304-7 (Pubitemid 36152484)
-
(2003)
Cancer Research
, vol.63
, Issue.2
, pp. 304-307
-
-
French, C.A.1
Miyoshi, I.2
Kubonishi, I.3
Grier, H.E.4
Perez-Atayde, A.R.5
Fletcher, J.A.6
-
16
-
-
41649120757
-
BRD-NUT oncoproteins: A family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells
-
DOI 10.1038/sj.onc.1210852, PII 1210852
-
French CA, Ramirez CL, Kolmakova J, Hickman TT, Cameron MJ, et al. 2008. BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells. Oncogene 27:2237-42 (Pubitemid 351483375)
-
(2008)
Oncogene
, vol.27
, Issue.15
, pp. 2237-2242
-
-
French, C.A.1
Ramirez, C.L.2
Kolmakova, J.3
Hickman, T.T.4
Cameron, M.J.5
Thyne, M.E.6
Kutok, J.L.7
Toretsky, J.A.8
Tadavarthy, A.K.9
Kees, U.R.10
Fletcher, J.A.11
Aster, J.C.12
-
17
-
-
0035180206
-
BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19)
-
French CA, Miyoshi I, Aster JC, Kubonishi I, Kroll TG, et al. 2001. BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19). Am. J. Pathol. 159:1987-92 (Pubitemid 33104253)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.6
, pp. 1987-1992
-
-
French, C.A.1
Miyoshi, I.2
Aster, J.C.3
Kubonishi, I.4
Kroll, T.G.5
Ci, P.D.6
Vargas, S.O.7
Perez-Atayde, A.R.8
Fletcher, J.A.9
-
18
-
-
79953320005
-
Differentiation of NUT midline carcinoma by epigenomic reprogramming
-
Schwartz BE, Hofer MD, Lemieux ME, Bauer DE, Cameron MJ, et al. 2011. Differentiation of NUT midline carcinoma by epigenomic reprogramming. Cancer Res. 71:2686-96
-
(2011)
Cancer Res.
, vol.71
, pp. 2686-96
-
-
Schwartz, B.E.1
Hofer, M.D.2
Lemieux, M.E.3
Bauer, D.E.4
Cameron, M.J.5
-
19
-
-
67649531792
-
Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody
-
Haack H, Johnson LA, Fry CJ, Crosby K, Polakiewicz RD, et al. 2009. Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody. Am. J. Surg. Pathol. 33:984-91
-
(2009)
Am. J. Surg. Pathol
, vol.33
, pp. 984-91
-
-
Haack, H.1
Johnson, L.A.2
Fry, C.J.3
Crosby, K.4
Polakiewicz, R.D.5
-
20
-
-
0025742958
-
Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma
-
Kubonishi I, Takehara N, Iwata J, Sonobe H, Ohtsuki Y, et al. 1991. Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma. Cancer Res. 51:3327-28
-
(1991)
Cancer Res
, vol.51
, pp. 3327-28
-
-
Kubonishi, I.1
Takehara, N.2
Iwata, J.3
Sonobe, H.4
Ohtsuki, Y.5
-
21
-
-
0025720075
-
Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19)
-
Kees UR, Mulcahy MT, Willoughby ML. 1991. Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19). Am. J. Pediatr. Hematol. Oncol. 13:459-64
-
(1991)
Am. J. Pediatr. Hematol. Oncol
, vol.13
, pp. 459-64
-
-
Kees, U.R.1
Mulcahy, M.T.2
Willoughby, M.L.3
-
22
-
-
0027275415
-
Disseminated mediastinal carcinoma with chromosomal translocation (15;19): A distinctive clinicopathologic syndrome
-
Lee AC, Kwong YI, Fu KH, Chan GC, Ma L, Lau YL. 1993. Disseminated mediastinal carcinoma with chromosomal translocation (15;19). A distinctive clinicopathologic syndrome. Cancer 72:2273-76 (Pubitemid 23280160)
-
(1993)
Cancer
, vol.72
, Issue.7
, pp. 2273-2276
-
-
Lee, A.C.W.1
Kwong, Y.-L.2
Fu, K.H.3
Chan, G.C.F.4
Ma, L.5
Lau, Y.-L.6
-
23
-
-
0035446797
-
Upper respiratory tract carcinoma with chromosomal translocation 15;19: Evidence for a distinct disease entity of young patients with a rapidly fatal course
-
DOI 10.1002/1097-0142(20010901)92:5<1195::AID-CNCR1438>3.0.CO;2-3
-
Vargas SO, French CA, Faul PN, Fletcher JA, Davis IJ, et al. 2001. Upper respiratory tract carcinoma with chromosomal translocation 15;19: evidence for a distinct disease entity of young patients with a rapidly fatal course. Cancer 92:1195-203 (Pubitemid 32861669)
-
(2001)
Cancer
, vol.92
, Issue.5
, pp. 1195-1203
-
-
Vargas, S.O.1
French, C.A.2
Faul, P.N.3
Fletcher, J.A.4
Davis, I.J.5
DalCin, P.6
Perez-Atayde, A.R.7
-
24
-
-
0038517750
-
Translocation (11;15;19): A highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients
-
DOI 10.1097/00000421-200306000-00019
-
Toretsky JA, Jenson J, Sun CC, Eskenazi AE, Campbell A, et al. 2003. Translocation (11;15;19): a highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients. Am. J. Clin. Oncol. 26:300-6 (Pubitemid 36712648)
-
(2003)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.26
, Issue.3
, pp. 300-306
-
-
Toretsky, J.A.1
Jenson, J.2
Sun, C.-C.3
Eskenazi, A.E.4
Campbell, A.5
Hunger, S.P.6
Caires, A.7
Frantz, C.8
Hill, J.L.9
Stamberg, J.10
-
25
-
-
2042468820
-
Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes
-
DOI 10.1016/S0092-8674(04)00402-7, PII S0092867404004027
-
You J, Croyle JL, Nishimura A, Ozato K, Howley PM. 2004. Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 117:349-60 (Pubitemid 38534541)
-
(2004)
Cell
, vol.117
, Issue.3
, pp. 349-360
-
-
You, J.1
Croyle, J.L.2
Nishimura, A.3
Ozato, K.4
Howley, P.M.5
-
26
-
-
70349669271
-
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
-
Moriniere J, Rousseaux S, Steuerwald U, Soler-Lopez M, Curtet S, et al. 2009. Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. Nature 461:664-68
-
(2009)
Nature
, vol.461
, pp. 664-68
-
-
Moriniere, J.1
Rousseaux, S.2
Steuerwald, U.3
Soler-Lopez, M.4
Curtet, S.5
-
27
-
-
0041806599
-
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
-
DOI 10.1073/pnas.1433065100
-
Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. 2003. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. USA 100:8758-63 (Pubitemid 36899172)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.15
, pp. 8758-8763
-
-
Dey, A.1
Chitsaz, F.2
Abbasi, A.3
Misteli, T.4
Ozato, K.5
-
28
-
-
0033519641
-
Structure and ligand of a histone acetyltransferase bromodomain
-
DOI 10.1038/20974
-
Dhalluin C, Carlson JE, Zeng L, He C, Aggarwal AK, Zhou MM. 1999. Structure and ligand of a histone acetyltransferase bromodomain. Nature 399:491-96 (Pubitemid 29258857)
-
(1999)
Nature
, vol.399
, Issue.6735
, pp. 491-496
-
-
Dhalluin, C.1
Carlson, J.E.2
Zeng, L.3
He, C.4
Aggarwal, A.K.5
Zhou, M.-M.6
-
29
-
-
0033842522
-
2-to-M transition
-
DOI 10.1128/MCB.20.17.6537-6549.2000
-
Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, et al. 2000. A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G2-to-M transition. Mol. Cell Biol. 20:6537-49 (Pubitemid 30650239)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.17
, pp. 6537-6549
-
-
Dey, A.1
Ellenberg, J.2
Farina, A.3
Coleman, A.E.4
Maruyama, T.5
Sciortino, S.6
Lippincott-Schwartz, J.7
Ozato, K.8
-
30
-
-
23744514308
-
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
-
DOI 10.1016/j.molcel.2005.06.027, PII S1097276505014322
-
Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K. 2005. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNApolymerase II-dependent transcription. Mol. Cell 19:523-34 (Pubitemid 41140009)
-
(2005)
Molecular Cell
, vol.19
, Issue.4
, pp. 523-534
-
-
Moon, K.J.1
Mochizuki, K.2
Zhou, M.3
Jeong, H.-S.4
Brady, J.N.5
Ozato, K.6
-
31
-
-
42049095157
-
The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase
-
Mochizuki K, Nishiyama A, Jang MK, Dey A, Ghosh A, et al. 2008. The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase. J. Biol. Chem. 283:9040-48
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9040-48
-
-
Mochizuki, K.1
Nishiyama, A.2
Jang, M.K.3
Dey, A.4
Ghosh, A.5
-
32
-
-
23744467035
-
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
-
DOI 10.1016/j.molcel.2005.06.029, PII S1097276505014310
-
Yang Z, Yik JH, Chen R, He N, Jang MK, et al. 2005. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol. Cell 19:535-45 (Pubitemid 41140010)
-
(2005)
Molecular Cell
, vol.19
, Issue.4
, pp. 535-545
-
-
Yang, Z.1
Yik, J.H.N.2
Chen, R.3
He, N.4
Moon, K.J.5
Ozato, K.6
Zhou, Q.7
-
33
-
-
56749096290
-
Solution structure of the extraterminal domain of the bromodomain-containing protein BRD4
-
Lin YJ, Umehara T, Inoue M, Saito K, Kigawa T, et al. 2008. Solution structure of the extraterminal domain of the bromodomain-containing protein BRD4. Protein Sci. 17:2174-79
-
(2008)
Protein Sci
, vol.17
, pp. 2174-79
-
-
Lin, Y.J.1
Umehara, T.2
Inoue, M.3
Saito, K.4
Kigawa, T.5
-
34
-
-
33750356102
-
1 cell cycle arrest
-
DOI 10.1128/JVI.00804-06
-
Ottinger M, Christalla T, Nathan K, Brinkmann MM, Viejo-Borbolla A, Schulz TF. 2006. Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest. J. Virol. 80:10772-86 (Pubitemid 44628923)
-
(2006)
Journal of Virology
, vol.80
, Issue.21
, pp. 10772-10786
-
-
Ottinger, M.1
Christalla, T.2
Nathan, K.3
Brinkmann, M.M.4
Viejo-Borbolla, A.5
Schulz, T.F.6
-
35
-
-
77956394108
-
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
-
Reynoird N, Schwartz BE, Delvecchio M, Sadoul K, Meyers D, et al. 2010. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J. 29:2943-52
-
(2010)
EMBO J.
, vol.29
, pp. 2943-52
-
-
Reynoird, N.1
Schwartz, B.E.2
Delvecchio, M.3
Sadoul, K.4
Meyers, D.5
-
36
-
-
22244440809
-
Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro
-
DOI 10.1136/jmg.2004.029686
-
Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Gonzalez A, et al. 2005. Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro. J. Med. Genet. 42:558-64 (Pubitemid 40993831)
-
(2005)
Journal of Medical Genetics
, vol.42
, Issue.7
, pp. 558-564
-
-
Haruki, N.1
Kawaguchi, K.S.2
Eichenberger, S.3
Massion, P.P.4
Gonzalez, A.5
Gazdar, A.F.6
Minna, J.D.7
Carbone, D.P.8
Dang, T.P.9
-
37
-
-
33645995094
-
Histone acetylation- mediated chromatin compaction during mouse spermatogenesis
-
Govin J, Lestrat C, Caron C, Pivot-Pajot C, Rousseaux S, Khochbin S. 2006. Histone acetylation- mediated chromatin compaction during mouse spermatogenesis. Ernst Schering Res. Found. Workshop 2006:155-72
-
(2006)
Ernst Schering Res. Found. Workshop
, vol.2006
, pp. 155-72
-
-
Govin, J.1
Lestrat, C.2
Caron, C.3
Pivot-Pajot, C.4
Rousseaux, S.5
Khochbin, S.6
-
38
-
-
0042090936
-
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein
-
DOI 10.1128/MCB.23.15.5354-5365.2003
-
Pivot-Pajot C, Caron C, Govin J, Vion A, Rousseaux S, Khochbin S. 2003. Acetylation-dependent chromatin reorganization byBRDT, a testis-specific bromodomain-containing protein. Mol. Cell Biol. 23:5354-65 (Pubitemid 36950890)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.15
, pp. 5354-5365
-
-
Pivot-Pajot, C.1
Caron, C.2
Govin, J.3
Vion, A.4
Rousseaux, S.5
Khochbin, S.6
-
39
-
-
0042924440
-
An activated receptor tyrosine kinase, TEL/PDGFβR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice
-
DOI 10.1073/pnas.1531730100
-
Grisolano JL, O'Neal J, Cain J, Tomasson MH. 2003. An activated receptor tyrosine kinase, TEL/PDGFR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. Proc. Natl. Acad. Sci. USA 100:9506-11 (Pubitemid 37033958)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9506-9511
-
-
Grisolano, J.L.1
O'Neal, J.2
Cain, J.3
Tomasson, M.H.4
-
40
-
-
23744498520
-
Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22)
-
DOI 10.1038/sj.leu.2403803
-
Nanri T, Matsuno N, Kawakita T, Suzushima H, Kawano F, et al. 2005. Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22). Leukemia 19:1361-66 (Pubitemid 41136329)
-
(2005)
Leukemia
, vol.19
, Issue.8
, pp. 1361-1366
-
-
Nanri, T.1
Matsuno, N.2
Kawakita, T.3
Suzushima, H.4
Kawano, F.5
Mitsuya, H.6
Asou, N.7
-
41
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M, Yokota S, Iwai T, Kaneko H, Horiike S, et al. 1996. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia 10:1911-18 (Pubitemid 27019637)
-
(1996)
Leukemia
, vol.10
, Issue.12
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
Kaneko, H.4
Horiike, S.5
Kashima, K.6
Sonoda, Y.7
Fujimoto, T.8
Misawa, S.9
-
42
-
-
66149092582
-
Exome sequencing takes centre stage in cancer profiling
-
Maher B. 2009. Exome sequencing takes centre stage in cancer profiling. Nature 459:146-47
-
(2009)
Nature
, vol.459
, pp. 146-47
-
-
Maher, B.1
-
43
-
-
33144469085
-
Glutamineexpanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction
-
Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, et al. 2006. Glutamineexpanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. PLoS Biol. 4:e67
-
(2006)
PLoS Biol
, vol.4
-
-
Helmlinger, D.1
Hardy, S.2
Abou-Sleymane, G.3
Eberlin, A.4
Bowman, A.B.5
-
44
-
-
0035909999
-
Histone deacetylase inhibitors reduce polyglutamine toxicity
-
DOI 10.1073/pnas.261400698
-
McCampbell A, Taye AA, Whitty L, Penney E, Steffan JS, Fischbeck KH. 2001. Histone deacetylase inhibitors reduce polyglutamine toxicity. Proc. Natl. Acad. Sci. USA 98:15179-84 (Pubitemid 34013989)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.26
, pp. 15179-15184
-
-
McCampbell, A.1
Taye, A.A.2
Whitty, L.3
Penney, E.4
Steffan, J.S.5
Fischbeck, K.H.6
-
45
-
-
0034285017
-
CREB-binding protein sequestration by expanded polyglutamine
-
McCampbell A, Taylor JP, Taye AA, Robitschek J, Li M, et al. 2000. CREB-binding protein sequestration by expanded polyglutamine. Hum. Mol. Genet. 9:2197-202
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 2197-202
-
-
McCampbell, A.1
Taylor, J.P.2
Taye, A.A.3
Robitschek, J.4
Li, M.5
-
46
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
DOI 10.1038/35099568
-
Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, et al. 2001. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 413:739-43 (Pubitemid 33009952)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
Zhu, Y.-Z.9
Greenwald, M.10
Kurokawa, R.11
Housman, D.E.12
Jackson, G.R.13
Marsh, J.L.14
Thompson, L.M.15
-
47
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
DOI 10.1182/blood-2006-06-025999
-
Duvic M, Talpur R, Ni X, Zhang C, Hazarika P, et al. 2007. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 109:31-39 (Pubitemid 46053039)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
Zhang, C.4
Hazarika, P.5
Kelly, C.6
Chiao, J.H.7
Reilly, J.F.8
Ricker, J.L.9
Richon, V.M.10
Frankel, S.R.11
-
48
-
-
0030739980
-
Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid
-
Redner RL, Corey SJ, Rush EA. 1997. Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid. Leukemia 11:1014-16 (Pubitemid 27345950)
-
(1997)
Leukemia
, vol.11
, Issue.7
, pp. 1014-1016
-
-
Redner, R.L.1
Corey, S.J.2
Rush, E.A.3
-
49
-
-
0032487923
-
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
-
DOI 10.1056/NEJM199811053391901
-
Soignet SL, Maslak P, Wang ZG, Jhanwar S, Calleja E, et al. 1998. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N. Engl. J. Med. 339:1341-48 (Pubitemid 28509343)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.19
, pp. 1341-1348
-
-
Soignet, S.L.1
Maslak, P.2
Wang, Z.-G.3
Jhanwar, S.4
Calleja, E.5
Dardashti, L.J.6
Corso, D.7
DeBlasio, A.8
Gabrilove, J.9
Scheinberg, D.A.10
Pandolfi, P.P.11
Warrell Jr., R.P.12
-
50
-
-
62549083523
-
Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia
-
Hu J, Liu YF, Wu CF, Xu F, Shen ZX, et al. 2009. Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 106:3342-47
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 3342-47
-
-
Hu, J.1
Liu, Y.F.2
Wu, C.F.3
Xu, F.4
Shen, Z.X.5
-
51
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
-
DOI 10.1038/sj.onc.1204704
-
Tuveson DA, Willis NA, Jacks T, Griffin JD, Singer S, et al. 2001. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene 20:5054-58 (Pubitemid 32769795)
-
(2001)
Oncogene
, vol.20
, Issue.36
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
Griffin, J.D.4
Singer, S.5
Fletcher, C.D.M.6
Fletcher, J.A.7
Demetri, G.D.8
-
52
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez JG, J'anne PA, Lee JC, Tracy S, Greulich H, et al. 2004. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304:1497-500 (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
53
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, et al. 1996. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med. 2:561-66
-
(1996)
Nat. Med
, vol.2
, pp. 561-66
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
-
54
-
-
77956513286
-
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
-
Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, et al. 2010. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 467:596-99
-
(2010)
Nature
, vol.467
, pp. 596-99
-
-
Bollag, G.1
Hirth, P.2
Tsai, J.3
Zhang, J.4
Ibrahim, P.N.5
-
55
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, et al. 2010. Selective inhibition of BET bromodomains. Nature 468:1067-73
-
(2010)
Nature
, vol.468
, pp. 1067-73
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
-
56
-
-
0031782323
-
The leukemic protein core binding factor β (CBFβ)-smooth-muscle myosin heavy chain sequesters CBFα2 into cytoskeletal filaments and aggregates
-
Adya N, Stacy T, Speck NA, Liu PP. 1998. The leukemic protein core binding factor (CBF)-smoothmuscle myosin heavy chain sequesters CBF2 into cytoskeletal filaments and aggregates. Mol. Cell Biol. 18:7432-43 (Pubitemid 28533062)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.12
, pp. 7432-7443
-
-
Adya, N.1
Stacy, T.2
Speck, N.A.3
Liu, P.P.4
-
57
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, et al. 2010. Suppression of inflammation by a synthetic histone mimic. Nature 468:1119-23
-
(2010)
Nature
, vol.468
, pp. 1119-23
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
Beinke, S.4
Dewell, S.5
-
58
-
-
0034674896
-
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
-
Dang TP, Gazdar AF, Virmani AK, Sepetavec T, Hande KR, et al. 2000. Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. J. Natl. Cancer Inst. 92:1355-57 (Pubitemid 30660597)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.16
, pp. 1355-1357
-
-
Dang, T.P.1
Gazdar, A.F.2
Virmani, A.K.3
Sepetavec, T.4
Hande, K.R.5
Minna, J.D.6
Roberts, J.R.7
Carbone, D.P.8
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