Identification of HEXIM1 as a positive regulator of p53

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36443-36454

  Lew, Qiao Jing ^a   Chia, Yi Ling ^a   Chu, Kai Ling ^a   Lam, Yuen Ting ^a   Gurumurthy, Meera ^a   Xu, Shengli ^a,b   Lam, Kong Peng ^a,b   Cheong, Nge ^a,b   Chao, Sheng Hao ^a,b  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA; ANTI-CANCER AGENTS; ANTICANCER DRUG; BREAST CANCER; C-TERMINAL REGIONS; CELL-CYCLE ARREST; COLORECTAL CARCINOMA; DOXORUBICIN; ETOPOSIDE; MOLECULAR MECHANISM; MRNA SYNTHESIS; NUCLEOPHOSMIN; OVER-EXPRESSION; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN LEVEL; PROTEIN STABILITY; PROTEIN-PROTEIN INTERACTIONS; RNA POLYMERASE II; ROSCOVITINE; SIGNALING PATHWAYS; TARGET GENES; UBIQUITINATION; UP-REGULATION;

BIOSYNTHESIS; DISEASES; GENES; PROTEINS; RNA; ULTRAVIOLET RADIATION;

TRANSCRIPTION;

DOXORUBICIN; ETOPOSIDE; FLAVOPIRIDOL; HEXAMETHYLENE BISACETAMIDE INDUCIBLE PROTEIN 1; NUTLIN 3; PROTEIN MDM2; PROTEIN P53; REGULATOR PROTEIN; ROSCOVITINE; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG TARGETING; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; P21 GENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PUMA GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UBIQUITINATION; ULTRAVIOLET RADIATION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA POLYMERASE II; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 84867835635     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.374157     Document Type: Article

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