메뉴 건너뛰기




Volumn 287, Issue 14, 2012, Pages 10738-10752

Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULES; PROTEINS;

EID: 84859479811     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.323493     Document Type: Article
Times cited : (109)

References (39)
  • 1
    • 0141994824 scopus 로고    scopus 로고
    • Perturbations of chromatin structure in human genetic disease: Recent advances
    • Bickmore, W. A., and van der Maarel, S. M. (2003) Perturbations of chromatin structure in human genetic disease. Recent advances. Hum. Mol. Genet 12, R207-213 (Pubitemid 37259334)
    • (2003) Human Molecular Genetics , vol.12 , Issue.REV. ISS. 2
    • Bickmore, W.A.1    Van Der Maarel, S.M.2
  • 3
    • 9444285838 scopus 로고    scopus 로고
    • Molecular biology. A higher order of silence
    • Mohd-Sarip, A., and Verrijzer, C. P. (2004) Molecular biology. A higher order of silence. Science 306, 1484-1485
    • (2004) Science , vol.306 , pp. 1484-1485
    • Mohd-Sarip, A.1    Verrijzer, C.P.2
  • 4
    • 33847106524 scopus 로고    scopus 로고
    • Higher-order structures of chromatin. The elusive 30 nm fiber
    • Tremethick, D. J. (2007) Higher-order structures of chromatin. The elusive 30 nm fiber. Cell 128, 651-654
    • (2007) Cell , vol.128 , pp. 651-654
    • Tremethick, D.J.1
  • 6
    • 9444297879 scopus 로고    scopus 로고
    • Nucleosome arrays reveal the two-start organization of the chromatin fiber
    • DOI 10.1126/science.1103124
    • Dorigo, B., Schalch, T., Kulangara, A., Duda, S., Schroeder, R. R., and Richmond, T. J. (2004) Nucleosome arrays reveal the two-start organization of the chromatin fiber. Science 306, 1571-1573 (Pubitemid 39564956)
    • (2004) Science , vol.306 , Issue.5701 , pp. 1571-1573
    • Dorigo, B.1    Schalch, T.2    Kulangara, A.3    Duda, S.4    Schroeder, R.R.5    Richmond, T.J.6
  • 7
    • 21844436803 scopus 로고    scopus 로고
    • X-ray structure of a tetranucleosome and its implications for the chromatin fibre
    • DOI 10.1038/nature03686
    • Schalch, T., Duda, S., Sargent, D. F., and Richmond, T. J. (2005) X-ray structure of a tetranucleosome and its implications for the chromatin fiber. Nature 436, 138-141 (Pubitemid 40966200)
    • (2005) Nature , vol.436 , Issue.7047 , pp. 138-141
    • Schalch, T.1    Duda, S.2    Sargent, D.F.3    Richmond, T.J.4
  • 8
    • 33646242052 scopus 로고    scopus 로고
    • EM measurements define the dimensions of the "30-nm" chromatin fiber. Evidence for a compact, interdigitated structure
    • Robinson, P. J., Fairall, L., Huynh, V. A., and Rhodes, D. (2006) EM measurements define the dimensions of the "30-nm" chromatin fiber. Evidence for a compact, interdigitated structure. Proc. Natl. Acad. Sci. U.S.A. 103, 6506-6511
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 6506-6511
    • Robinson, P.J.1    Fairall, L.2    Huynh, V.A.3    Rhodes, D.4
  • 9
    • 44649122151 scopus 로고    scopus 로고
    • Role of histone modifications in defining chromatin structure and function
    • DOI 10.1515/BC.2008.048
    • Gelato, K. A., and Fischle, W. (2008) Role of histone modifications in defining chromatin structure and function. Biol. Chem. 389, 353-363 (Pubitemid 351773917)
    • (2008) Biological Chemistry , vol.389 , Issue.4 , pp. 353-363
    • Gelato, K.A.1    Fischle, W.2
  • 11
    • 34547858913 scopus 로고    scopus 로고
    • Structure and acetyl-lysine recognition of the bromodomain
    • DOI 10.1038/sj.onc.1210618, PII 1210618
    • Mujtaba, S., Zeng, L., and Zhou, M. M. (2007) Structure and acetyl-lysine recognition of the bromodomain. Oncogene 26, 5521-5527 (Pubitemid 47255932)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5521-5527
    • Mujtaba, S.1    Zeng, L.2    Zhou, M.-M.3
  • 14
    • 0036091456 scopus 로고    scopus 로고
    • Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4
    • DOI 10.1128/MCB.22.11.3794-3802.2002
    • Houzelstein, D., Bullock, S. L., Lynch, D. E., Grigorieva, E. F., Wilson, V. A., and Beddington, R. S. (2002) Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol. Cell. Biol. 22, 3794-3802 (Pubitemid 34525221)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.11 , pp. 3794-3802
    • Houzelstein, D.1    Bullock, S.L.2    Lynch, D.E.3    Grigorieva, E.F.4    Wilson, V.A.5    Beddington, R.S.P.6
  • 16
    • 31944442800 scopus 로고    scopus 로고
    • Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: Preservation of acetylated chromatin
    • DOI 10.1091/mbc.E05-08-0729
    • Nishiyama, A., Dey, A., Miyazaki, J., and Ozato, K. (2006) Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest. Preservation of acetylated chromatin. Mol. Biol. Cell 17, 814-823 (Pubitemid 43191115)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.2 , pp. 814-823
    • Nishiyama, A.1    Dey, A.2    Miyazaki, J.-I.3    Ozato, K.4
  • 18
    • 38549113034 scopus 로고    scopus 로고
    • 1 gene expression and cell cycle progression
    • DOI 10.1128/MCB.01020-07
    • Yang, Z., He, N., and Zhou, Q. (2008) Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. Mol. Cell. Biol. 28, 967-976 (Pubitemid 351160053)
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.3 , pp. 967-976
    • Yang, Z.1    He, N.2    Zhou, Q.3
  • 19
    • 2042468820 scopus 로고    scopus 로고
    • Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes
    • DOI 10.1016/S0092-8674(04)00402-7, PII S0092867404004027
    • You, J., Croyle, J. L., Nishimura, A., Ozato, K., and Howley, P. M. (2004) Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 117, 349-360 (Pubitemid 38534541)
    • (2004) Cell , vol.117 , Issue.3 , pp. 349-360
    • You, J.1    Croyle, J.L.2    Nishimura, A.3    Ozato, K.4    Howley, P.M.5
  • 20
    • 33748484257 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes
    • DOI 10.1128/JVI.00502-06
    • You, J., Srinivasan, V., Denis, G. V., Harrington, W. J., Jr., Ballestas, M. E., Kaye, K. M., and Howley, P. M. (2006) Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes. J. Virol. 80, 8909-8919 (Pubitemid 44359965)
    • (2006) Journal of Virology , vol.80 , Issue.18 , pp. 8909-8919
    • You, J.1    Srinivasan, V.2    Denis, G.V.3    Harrington Jr., W.J.4    Ballestas, M.E.5    Kaye, K.M.6    Howley, P.M.7
  • 21
    • 33750356102 scopus 로고    scopus 로고
    • 1 cell cycle arrest
    • DOI 10.1128/JVI.00804-06
    • Ottinger, M., Christalla, T., Nathan, K., Brinkmann, M. M., Viejo-Borbolla, A., and Schulz, T. F. (2006) Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest. J. Virol. 80, 10772-10786 (Pubitemid 44628923)
    • (2006) Journal of Virology , vol.80 , Issue.21 , pp. 10772-10786
    • Ottinger, M.1    Christalla, T.2    Nathan, K.3    Brinkmann, M.M.4    Viejo-Borbolla, A.5    Schulz, T.F.6
  • 22
    • 57349095971 scopus 로고    scopus 로고
    • The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4
    • Lin, A., Wang, S., Nguyen, T., Shire, K., and Frappier, L. (2008) The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J. Virol. 82, 12009-12019
    • (2008) J. Virol. , vol.82 , pp. 12009-12019
    • Lin, A.1    Wang, S.2    Nguyen, T.3    Shire, K.4    Frappier, L.5
  • 27
    • 23744467035 scopus 로고    scopus 로고
    • Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
    • DOI 10.1016/j.molcel.2005.06.029, PII S1097276505014310
    • Yang, Z., Yik, J. H., Chen, R., He, N., Jang, M. K., Ozato, K., and Zhou, Q. (2005) Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol. Cell 19, 535-545 (Pubitemid 41140010)
    • (2005) Molecular Cell , vol.19 , Issue.4 , pp. 535-545
    • Yang, Z.1    Yik, J.H.N.2    Chen, R.3    He, N.4    Moon, K.J.5    Ozato, K.6    Zhou, Q.7
  • 29
    • 23744514308 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
    • DOI 10.1016/j.molcel.2005.06.027, PII S1097276505014322
    • Jang, M. K., Mochizuki, K., Zhou, M., Jeong, H. S., Brady, J. N., and Ozato, K. (2005) The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol. Cell 19, 523-534 (Pubitemid 41140009)
    • (2005) Molecular Cell , vol.19 , Issue.4 , pp. 523-534
    • Moon, K.J.1    Mochizuki, K.2    Zhou, M.3    Jeong, H.-S.4    Brady, J.N.5    Ozato, K.6
  • 30
    • 41549115095 scopus 로고    scopus 로고
    • The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription
    • DOI 10.1016/j.molcel.2008.01.018, PII S1097276508001573
    • LeRoy, G., Rickards, B., and Flint, S. J. (2008) The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol. Cell 30, 51-60 (Pubitemid 351470152)
    • (2008) Molecular Cell , vol.30 , Issue.1 , pp. 51-60
    • LeRoy, G.1    Rickards, B.2    Flint, S.J.3
  • 31
    • 0042090936 scopus 로고    scopus 로고
    • Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein
    • DOI 10.1128/MCB.23.15.5354-5365.2003
    • Pivot-Pajot, C., Caron, C., Govin, J., Vion, A., Rousseaux, S., and Khochbin, S. (2003) Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. Mol. Cell. Biol. 23, 5354-5365 (Pubitemid 36950890)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.15 , pp. 5354-5365
    • Pivot-Pajot, C.1    Caron, C.2    Govin, J.3    Vion, A.4    Rousseaux, S.5    Khochbin, S.6
  • 32
    • 72849149501 scopus 로고    scopus 로고
    • Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression
    • Yan, J., Li, Q., Lievens, S., Tavernier, J., and You, J. (2010) Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression. J. Virol. 84, 76-87
    • (2010) J. Virol. , vol.84 , pp. 76-87
    • Yan, J.1    Li, Q.2    Lievens, S.3    Tavernier, J.4    You, J.5
  • 33
    • 70249141638 scopus 로고    scopus 로고
    • Regulation of aurora B expression by the bromodomain protein Brd4
    • You, J., Li, Q., Wu, C., Kim, J., Ottinger, M., and Howley, P. M. (2009) Regulation of aurora B expression by the bromodomain protein Brd4. Mol. Cell Biol. 29, 5094-5103
    • (2009) Mol. Cell Biol. , vol.29 , pp. 5094-5103
    • You, J.1    Li, Q.2    Wu, C.3    Kim, J.4    Ottinger, M.5    Howley, P.M.6
  • 34
    • 79960972120 scopus 로고    scopus 로고
    • Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinoma
    • Yan, J., Diaz, J., Jiao, J., Wang, R., and You, J. (2011) Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinoma. J. Biol. Chem. 286, 27663-27675
    • (2011) J. Biol. Chem. , vol.286 , pp. 27663-27675
    • Yan, J.1    Diaz, J.2    Jiao, J.3    Wang, R.4    You, J.5
  • 37
    • 34347222583 scopus 로고    scopus 로고
    • Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells
    • Kerppola, T. K. (2006) Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells. Nat. Protoc. 1, 1278-1286
    • (2006) Nat. Protoc. , vol.1 , pp. 1278-1286
    • Kerppola, T.K.1
  • 38
    • 0036138908 scopus 로고    scopus 로고
    • A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications
    • DOI 10.1038/nbt0102-87
    • Nagai, T., Ibata, K., Park, E. S., Kubota, M., Mikoshiba, K., and Miyawaki, A. (2002) A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat. Biotechnol. 20, 87-90 (Pubitemid 34044921)
    • (2002) Nature Biotechnology , vol.20 , Issue.1 , pp. 87-90
    • Nagai, T.1    Ibata, K.2    Park, E.S.3    Kubota, M.4    Mikoshiba, K.5    Miyawaki, A.6
  • 39
    • 4744366751 scopus 로고    scopus 로고
    • Bromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localization
    • DOI 10.1128/MCB.24.20.9059-9069.2004
    • Farina, A., Hattori, M., Qin, J., Nakatani, Y., Minato, N., and Ozato, K. (2004) Bromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localization. Mol. Cell Biol. 24, 9059-9069 (Pubitemid 39313910)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.20 , pp. 9059-9069
    • Farina, A.1    Hattori, M.2    Qin, J.3    Nakatani, Y.4    Minato, N.5    Ozato, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.