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Volumn 19, Issue 38, 2013, Pages 6726-6731

Resveratrol: New avenues for a natural compound in neuroprotection

Author keywords

Aging; Autophagy; Inflammation; Neurodegeneration; Polyphenols; Resveratrol; Sirtuin 1

Indexed keywords

ANTIOXIDANT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RESVERATROL; SIRTUIN 1; BIOLOGICAL PRODUCT; NEUROPROTECTIVE AGENT; SIRT1 PROTEIN, HUMAN; STILBENE DERIVATIVE;

EID: 84896363752     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319380005     Document Type: Article
Times cited : (71)

References (83)
  • 1
    • 0034003010 scopus 로고    scopus 로고
    • Isolation and identification of stilbenes in two varieties of Polygonum cuspi-datum
    • [1] Vastano BC, Chen Y, Zhu N, Ho CT, Zhou Z, Rosen RT. Isolation and identification of stilbenes in two varieties of Polygonum cuspi-datum. J. Agri. Food Chem 2000; 48(2): 253-6.
    • (2000) J. Agri. Food Chem , vol.48 , Issue.2 , pp. 253-256
    • Vastano, B.C.1    Chen, Y.2    Zhu, N.3    Ho, C.T.4    Zhou, Z.5    Rosen, R.T.6
  • 2
    • 78650902065 scopus 로고    scopus 로고
    • Neuroprotective prop- erties of resveratrol in different neurodegenerative disorders
    • [2] Albani D, Polito L, Signorini A, Forloni G. Neuroprotective prop- erties of resveratrol in different neurodegenerative disorders. Bio-Factors 2010; 36(5): 370-76.
    • (2010) Bio-Factors , vol.36 , Issue.5 , pp. 370-376
    • Albani, D.1    Polito, L.2    Signorini, A.3    Forloni, G.4
  • 3
    • 79959261445 scopus 로고    scopus 로고
    • What is new for an old mole- cule? Systematic review and recommendations on the use of res-veratrol
    • [3] Vang O, Ahmad N, Baile CA, et al. What is new for an old mole- cule? systematic review and recommendations on the use of res-veratrol. PloS One 2011; 6(6): e19881.
    • (2011) Plos One , vol.6 , Issue.6
    • Vang, O.1    Ahmad, N.2    Baile, C.A.3
  • 4
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activa- tors of sirtuins extend Saccharomyces cerevisiae lifespan
    • [4] Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activa- tors of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003; 425(6954): 191-6.
    • (2003) Nature , vol.425 , Issue.6954 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3
  • 5
    • 34848927457 scopus 로고    scopus 로고
    • Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans
    • [5] Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mech Ageing Dev 2007; 128(10): 546-52.
    • (2007) Mech Ageing Dev , vol.128 , Issue.10 , pp. 546-552
    • Bass, T.M.1    Weinkove, D.2    Houthoofd, K.3    Gems, D.4    Partridge, L.5
  • 6
    • 31944450272 scopus 로고    scopus 로고
    • Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
    • [6] Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol 2006; 16(3): 296-300.
    • (2006) Curr Biol , vol.16 , Issue.3 , pp. 296-300
    • Valenzano, D.R.1    Terzibasi, E.2    Genade, T.3    Cattaneo, A.4    Domenici, L.5    Cellerino, A.6
  • 7
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • [7] Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006; 444(7117): 337-42.
    • (2006) Nature , vol.444 , Issue.7117 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 11
    • 78851470225 scopus 로고    scopus 로고
    • Resveratrol and life extension
    • [11] Agarwal B, Baur JA. Resveratrol and life extension. Ann New York Acad Sci 2011; 1215: 138-43.
    • (2011) Ann New York Acad Sci , vol.1215 , pp. 138-143
    • Agarwal, B.1    Baur, J.A.2
  • 12
    • 52649144195 scopus 로고    scopus 로고
    • Resveratrol and novel potent activators of SIRT1: Effects on aging and age-related diseases
    • [12] Knutson MD, Leeuwenburgh C. Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases. Nutrition Rev 2008; 66(10): 591-6.
    • (2008) Nutrition Rev , vol.66 , Issue.10 , pp. 591-596
    • Knutson, M.D.1    Leeuwenburgh, C.2
  • 13
    • 84863328591 scopus 로고    scopus 로고
    • The journey of resveratrol from yeast to human
    • [13] Timmers S, Auwerx J, Schrauwen P. The journey of resveratrol from yeast to human. Aging (Albany NY) 2012; 4(3): 146-58.
    • (2012) Aging (Albany NY) , vol.4 , Issue.3 , pp. 146-158
    • Timmers, S.1    Auwerx, J.2    Schrauwen, P.3
  • 15
    • 77249166617 scopus 로고    scopus 로고
    • Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in Rats
    • [15] Juan ME, González-Pons E, Planas JM. Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in Rats. J Nutrition 2010; 140(3): 489-95.
    • (2010) J Nutrition , vol.140 , Issue.3 , pp. 489-495
    • Juan, M.E.1    González-Pons, E.2    Planas, J.M.3
  • 17
    • 34248146970 scopus 로고    scopus 로고
    • Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat
    • [17] Mokni M, Ekahoui S, Limam F, Amri M, Aouani E. Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat. Neurochem Res 2007; 32(6): 981-7.
    • (2007) Neurochem Res , vol.32 , Issue.6 , pp. 981-987
    • Mokni, M.1    Ekahoui, S.2    Limam, F.3    Amri, M.4    Aouani, E.5
  • 18
    • 0037184675 scopus 로고    scopus 로고
    • Resveratrol protects against global cerebral ischemic injury in gerbils
    • [18] Wang Q, Xu J, Rottinghaus GE, et al. Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 2002; 958(2): 439-47.
    • (2002) Brain Res , vol.958 , Issue.2 , pp. 439-447
    • Wang, Q.1    Xu, J.2    Rottinghaus, G.E.3
  • 19
    • 33750159449 scopus 로고    scopus 로고
    • Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses
    • [19] Mattson MP, Cheng A. Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses. Trends Neu-rosci 2006; 29(11): 632-9.
    • (2006) Trends Neu-Rosci , vol.29 , Issue.11 , pp. 632-639
    • Mattson, M.P.1    Cheng, A.2
  • 20
    • 0030661964 scopus 로고    scopus 로고
    • Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests
    • [20] Fauconneau B, Waffo-Teguo P, Huguet F, Barrier L, Decendit A, Merillon JM. Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests. Life Sci 1997; 61(21): 2103-10
    • (1997) Life Sci , vol.61 , Issue.21 , pp. 2103-2110
    • Fauconneau, B.1    Waffo-Teguo, P.2    Huguet, F.3    Barrier, L.4    Decendit, A.5    Merillon, J.M.6
  • 21
    • 84858749951 scopus 로고    scopus 로고
    • Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
    • [21] Cristòfol R, Porquet D, Corpas R, et al. Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol. J Pineal Res 2012; 52(3): 271-81.
    • (2012) J Pineal Res , vol.52 , Issue.3 , pp. 271-281
    • Cristòfol, R.1    Porquet, D.2    Corpas, R.3
  • 22
    • 0034795205 scopus 로고    scopus 로고
    • Oxidized lipoproteins, beta amyloid peptides and Alzheimer's disease
    • [22] Sun AY, Draczynska-Lusiak B, Sun GY. Oxidized lipoproteins, beta amyloid peptides and Alzheimer's disease. Neurotox Res 2001; 3(2): 167-78.
    • (2001) Neurotox Res , vol.3 , Issue.2 , pp. 167-178
    • Sun, A.Y.1    Draczynska-Lusiak, B.2    Sun, G.Y.3
  • 23
    • 84867581047 scopus 로고    scopus 로고
    • Resveratrol attenuates oxidative damage and ameliorates cognitive impairment in the brain of senescence-accelerated mice
    • [23] Liu GS, Zhang ZS, Yang B, He W. Resveratrol attenuates oxidative damage and ameliorates cognitive impairment in the brain of senescence-accelerated mice. Life Sci 2012; 91(17-18): 872-7.
    • (2012) Life Sci , vol.91 , Issue.17-18 , pp. 872-877
    • Liu, G.S.1    Zhang, Z.S.2    Yang, B.3    He, W.4
  • 24
    • 84855283935 scopus 로고    scopus 로고
    • Resveratrol protects rats from A|3-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation
    • [24] Huang TC, Lu KT, Wo YY, Wu YJ, Yang YL. Resveratrol protects rats from A|3-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation. PLoS One 2011; 6(12): e29102.
    • (2011) Plos One , vol.6 , Issue.12
    • Huang, T.C.1    Lu, K.T.2    Wo, Y.Y.3    Wu, Y.J.4    Yang, Y.L.5
  • 25
    • 84859159081 scopus 로고    scopus 로고
    • Transgenic expression and activation of PGC-1a protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease
    • [25] Mudò G, Mäkelä J, Di Liberto V, et al. Transgenic expression and activation of PGC-1a protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease. Cell Mol Life Sci 2012; 69(7): 1153-65
    • (2012) Cell Mol Life Sci , vol.69 , Issue.7 , pp. 1153-1165
    • Mudò, G.1    Mäkelä, J.2    Di Liberto, V.3
  • 26
    • 80755129036 scopus 로고    scopus 로고
    • Resveratrol pretreatment attenuates cerebral ischemic injury by upregulating expression of transcription factor Nrf2 and HO-1 in rats
    • [26] Ren J, Fan C, Chen N, Huang J, Yang Q. Resveratrol pretreatment attenuates cerebral ischemic injury by upregulating expression of transcription factor Nrf2 and HO-1 in rats. Neurochem Res 2011; 36(12): 2352-62.
    • (2011) Neurochem Res , vol.36 , Issue.12 , pp. 2352-2362
    • Ren, J.1    Fan, C.2    Chen, N.3    Huang, J.4    Yang, Q.5
  • 27
    • 84878014110 scopus 로고    scopus 로고
    • Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins
    • S0955-2863(12)00212-4
    • [27] Wu PF, Xie N, Zhang JJ, et al. Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins. J Nutr Biochem 2012; S0955-2863(12)00212-4.
    • (2012) J Nutr Biochem
    • Wu, P.F.1    Xie, N.2    Zhang, J.J.3
  • 28
    • 78650747994 scopus 로고    scopus 로고
    • SIRT1 contributes to telomere maintenance and augments global homologous recombination
    • [28] Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M, Blasco MA. SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol 2010; 191(7): 1299-313.
    • (2010) J Cell Biol , vol.191 , Issue.7 , pp. 1299-1313
    • Palacios, J.A.1    Herranz, D.2    De Bonis, M.L.3    Velasco, S.4    Serrano, M.5    Blasco, M.A.6
  • 29
    • 3142740860 scopus 로고    scopus 로고
    • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
    • [29] Cohen HY, Miller C, Bitterman KJ, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305(5682): 390-2.
    • (2004) Science , vol.305 , Issue.5682 , pp. 390-392
    • Cohen, H.Y.1    Miller, C.2    Bitterman, K.J.3
  • 30
    • 67651210858 scopus 로고    scopus 로고
    • SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1
    • [30] Rajamohan SB, Pillai VB, Gupta M, et al. SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Mol Cell Biol 2009 29(15): 4116-29.
    • (2009) Mol Cell Biol , vol.29 , Issue.15 , pp. 4116-4129
    • Rajamohan, S.B.1    Pillai, V.B.2    Gupta, M.3
  • 31
    • 34547906123 scopus 로고    scopus 로고
    • Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
    • [31] Rodgers JT, Puigserver P. Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proc Natl Acad Sci USA 2007; 104(31): 12861-6.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.31 , pp. 12861-12866
    • Rodgers, J.T.1    Puigserver, P.2
  • 32
    • 77955499804 scopus 로고    scopus 로고
    • Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
    • [32] Lim JH, Lee YM, Chun YS, Chen J, Kim JE, Park JW. Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol Cell 2010; 38(6): 864-78.
    • (2010) Mol Cell , vol.38 , Issue.6 , pp. 864-878
    • Lim, J.H.1    Lee, Y.M.2    Chun, Y.S.3    Chen, J.4    Kim, J.E.5    Park, J.W.6
  • 33
    • 63449112017 scopus 로고    scopus 로고
    • Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
    • [33] Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab 2009; 9(4): 327-38.
    • (2009) Cell Metab , vol.9 , Issue.4 , pp. 327-338
    • Purushotham, A.1    Schug, T.T.2    Xu, Q.3    Surapureddi, S.4    Guo, X.5    Li, X.6
  • 34
    • 52049096152 scopus 로고    scopus 로고
    • Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons
    • [34] Hasegawa K, Yoshikawa K. Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci 2008; 28(35): 8772-84.
    • (2008) J Neurosci , vol.28 , Issue.35 , pp. 8772-8784
    • Hasegawa, K.1    Yoshikawa, K.2
  • 35
    • 35349011726 scopus 로고    scopus 로고
    • Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
    • [35] Kim EJ, Kho JH, Kang MR, Um SJ. Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol Cell 2007; 28(2): 277-90.
    • (2007) Mol Cell , vol.28 , Issue.2 , pp. 277-290
    • Kim, E.J.1    Kho, J.H.2    Kang, M.R.3    Um, S.J.4
  • 36
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • 26, 2011-5
    • [36] Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 26; 303(5666) 2011-5.
    • (2004) Science , vol.303 , Issue.5666
    • Brunet, A.1    Sweeney, L.B.2    Sturgill, J.F.3
  • 37
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • 16
    • [37] Yeung F, Hoberg JE, Ramsey CS, et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004 16; 23(12) 2369-80.
    • (2004) EMBO J , vol.23 , Issue.12 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3
  • 38
    • 67650439330 scopus 로고    scopus 로고
    • Caloric restriction delays disease onset and mortality in Rhesus monkeys
    • 10
    • [38] Colman RJ, Anderson RM, Johnson SC, et al. Caloric restriction delays disease onset and mortality in Rhesus monkeys. Science 2009 10; 325 (5937) 201-4.
    • (2009) Science , vol.325 , Issue.5937 , pp. 201-204
    • Colman, R.J.1    Erson, R.M.2    Johnson, S.C.3
  • 39
    • 84866163081 scopus 로고    scopus 로고
    • Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
    • [39] Mattison JA, Roth GS, Beasley TM, et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 2012; 489(7415): 318-21.
    • (2012) Nature , vol.489 , Issue.7415 , pp. 318-321
    • Mattison, J.A.1    Roth, G.S.2    Beasley, T.M.3
  • 40
    • 48349110303 scopus 로고    scopus 로고
    • A low dose of dietary resvera-trol partially mimics caloric restriction and retards aging parameters in mice
    • 4
    • [40] Barger JL, Kayo T, Vann JM, et al. A low dose of dietary resvera-trol partially mimics caloric restriction and retards aging parameters in mice. PLoS One 2008; 4; 3(6): e2264.
    • (2008) Plos One , vol.3 , Issue.6
    • Barger, J.L.1    Kayo, T.2    Vann, J.M.3
  • 41
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • [41] Pearson KJ, Baur JA, Lewis KN, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008; 8(2): 157-68.
    • (2008) Cell Metab , vol.8 , Issue.2 , pp. 68
    • Pearson, K.J.1    Baur, J.A.2    Lewis, K.N.3
  • 42
    • 63549094179 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
    • [42] Smith JJ, Kenney RD, Gagne DJ, et al. Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo. BMC Syst Biol 2009; 10: 30-1.
    • (2009) BMC Syst Biol , vol.10 , pp. 30-31
    • Smith, J.J.1    Kenney, R.D.2    Gagne, D.J.3
  • 43
    • 77958488312 scopus 로고    scopus 로고
    • SIRT1 Activation by Small Molecules: Kinetic and biophysical evidence for direct interaction of enzyme and activator
    • [43] Dai H, Kustigian L, Carney D, et al. SIRT1 Activation by Small Molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator. J Biol Chem 2010; 285(43): 32695-703.
    • (2010) J Biol Chem , vol.285 , Issue.43 , pp. 32695-32703
    • Dai, H.1    Kustigian, L.2    Carney, D.3
  • 44
    • 36248975293 scopus 로고    scopus 로고
    • SIRT1 transgenic mice show phenotypes resembling calorie restriction
    • [44] Bordone L, Cohen D, Robinson A, et al. SIRT1 transgenic mice show phenotypes resembling calorie restriction. Cell 2007; 6(6): 759-67.
    • (2007) Cell , vol.6 , Issue.6 , pp. 759-767
    • Bordone, L.1    Cohen, D.2    Robinson, A.3
  • 45
    • 20444444649 scopus 로고    scopus 로고
    • Mechanism of human SIRT1 activation by resveratrol
    • [45] Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 2005; 280(17): 17187-95.
    • (2005) J Biol Chem , vol.280 , Issue.17 , pp. 17187-17195
    • Borra, M.T.1    Smith, B.C.2    Denu, J.M.3
  • 46
    • 20444431507 scopus 로고    scopus 로고
    • Substrate-specific activation of sirtuins by resveratrol
    • [46] Kaeberlein M, McDonagh T, Heltweg B, et al. Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 2005; 280(17): 17038-45.
    • (2005) J Biol Chem , vol.280 , Issue.17 , pp. 17038-17045
    • Kaeberlein, M.1    Mcdonagh, T.2    Heltweg, B.3
  • 47
    • 70350524083 scopus 로고    scopus 로고
    • Resveratrol is not a direct activator of SIRT1 enzyme activity
    • [47] Beher D, Wu J, Cumine S, et al. Resveratrol is not a direct activator of SIRT1 enzyme activity. Chem Biol Drug Des 2009; 74(6): 619-24.
    • (2009) Chem Biol Drug Des , vol.74 , Issue.6 , pp. 619-624
    • Beher, D.1    Wu, J.2    Cumine, S.3
  • 48
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • [48] Michán S, Li Y, Chou MM, et al. SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci 2010; 30(29): 9695-707.
    • (2010) J Neurosci , vol.30 , Issue.29 , pp. 9695-9707
    • Michán, S.1    Li, Y.2    Chou, M.M.3
  • 49
    • 34249846128 scopus 로고    scopus 로고
    • Resveratrol stimulates AMP kinase activity in neurons
    • [49] Dasgupta B, Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci USA 2007; 104(17): 7217-22.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.17 , pp. 7217-7222
    • Dasgupta, B.1    Milbrandt, J.2
  • 50
    • 84863011114 scopus 로고    scopus 로고
    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodi-esterases
    • [50] Park SJ, Ahmad F, Philp A, et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodi-esterases. Cell 2012 148(3): 421-33.
    • (2012) Cell , vol.148 , Issue.3 , pp. 421-433
    • Park, S.J.1    Ahmad, F.2    Philp, A.3
  • 51
    • 67349273985 scopus 로고    scopus 로고
    • SIRT1: Regulation of longevity via autophagy
    • [51] Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal 2009; 21(9): 1356-66.
    • (2009) Cell Signal , vol.21 , Issue.9 , pp. 1356-1366
    • Salminen, A.1    Kaarniranta, K.2
  • 52
    • 83855164099 scopus 로고    scopus 로고
    • Morphological and biochemical studies on aging and autophagy
    • [52] Rezzani R, Stacchiotti A, Rodella LF. Morphological and biochemical studies on aging and autophagy. Ageing Res Rev 2012; 11(1): 10-31.
    • (2012) Ageing Res Rev , vol.11 , Issue.1 , pp. 10-31
    • Rezzani, R.1    Stacchiotti, A.2    Rodella, L.F.3
  • 53
    • 2642586352 scopus 로고    scopus 로고
    • Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
    • [53] Ravikumar B, Vacher C, Berger Z, et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet 2004; 36(6): 585-95.
    • (2004) Nat Genet , vol.36 , Issue.6 , pp. 585-595
    • Ravikumar, B.1    Vacher, C.2    Berger, Z.3
  • 54
    • 84863328591 scopus 로고    scopus 로고
    • The journey of resveratrol from yeast to human
    • [54] Timmers S, Auwerx J, Schrauwen P. The journey of resveratrol from yeast to human. Aging (Albany NY) 2012; 4(3): 146-58.
    • (2012) Aging (Albany NY) , vol.4 , Issue.3 , pp. 146-158
    • Timmers, S.1    Auwerx, J.2    Schrauwen, P.3
  • 55
    • 41549138483 scopus 로고    scopus 로고
    • A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagia
    • [55] Lee IH, Cao L, Mostoslavsky R, et al.: A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagia. Proc. Natl. Acad. Sci. USA 2008; 105: 3374-9.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 3374-3379
    • Lee, I.H.1    Cao, L.2    Mostoslavsky, R.3
  • 56
    • 77950127881 scopus 로고    scopus 로고
    • SIRT1 negatively regulates the mammalian target of rapamycin
    • 15
    • [56] Ghosh HS, McBurney M, Robbins PD. SIRT1 negatively regulates the mammalian target of rapamycin. PLoS One: 2010; 15; 5(2): e91995.
    • (2010) Plos One , vol.5 , Issue.2
    • Ghosh, H.S.1    Mcburney, M.2    Robbins, P.D.3
  • 57
    • 55549096745 scopus 로고    scopus 로고
    • SIRT1 modulation of the
    • [57] Lan F, Cacicedo JM, Ruderman N, Ido Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J Biol Chem 2008; 283: 27628-35.
    • (2008) J Biol Chem , vol.283 , pp. 27628-27635
    • Lan, F.1    Cacicedo, J.M.2    Ruderman, N.3    Ido, Y.4
  • 59
    • 61649103107 scopus 로고    scopus 로고
    • Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism?
    • [59] Ryter SW, Chen ZH, Kim HP, Choi AM. Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism? Autophagy 2009; 5: 235-7.
    • (2009) Autophagy , vol.5 , pp. 235-237
    • Ryter, S.W.1    Chen, Z.H.2    Kim, H.P.3    Choi, A.M.4
  • 60
    • 53749087325 scopus 로고    scopus 로고
    • Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
    • [60] Chen ZH, Kim HP, Sciurba FC, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease PLoS One 2008; 3: e3316.
    • (2008) Plos One , vol.3 , pp. e3316
    • Chen, Z.H.1    Kim, H.P.2    Sciurba, F.C.3
  • 61
    • 70349641034 scopus 로고    scopus 로고
    • Autophagy and the pancreatic beta-cell in human type 2 diabetes
    • [61] Marchetti P, Masini M. Autophagy and the pancreatic beta-cell in human type 2 diabetes. Autophagy 2009; 5: 1055-6.
    • (2009) Autophagy , vol.5 , pp. 1055-1056
    • Marchetti, P.1    Masini, M.2
  • 62
    • 77954251401 scopus 로고    scopus 로고
    • Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes
    • [62] Ost A, Svensson K, Ruishalme I, et al. Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes. Mol Med 2012; 16(7-8): 235-46.
    • (2012) Mol Med , vol.16 , Issue.7 , pp. 235-246
    • Ost, A.1    Svensson, K.2    Ruishalme, I.3
  • 63
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • [63] Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994; 12: 141-79.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 64
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-kappa B
    • [64] May MJ, Ghosh S. Signal transduction through NF-kappa B. Immunol Today 1998; 19: 80-8.
    • (1998) Immunol Today , vol.19 , pp. 80-88
    • May, M.J.1    Ghosh, S.2
  • 65
    • 77950189559 scopus 로고    scopus 로고
    • NF-kappaB inhibitory action of resveratrol: A probable mechanism of neuroprotection in experimental diabetic neuropathy
    • [65] Kumar A, Sharma SS. NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy. Biochem Biophys Res Commun 2010; 394(2): 360-5.
    • (2010) Biochem Biophys Res Commun , vol.394 , Issue.2 , pp. 360-365
    • Kumar, A.1    Sharma, S.S.2
  • 67
    • 80054899332 scopus 로고    scopus 로고
    • Resveratrol inhibition of inducible nitric oxide synthase in skeletal muscle involves AMPK but not SIRT1
    • [67] Centeno-Baez C, Dallaire P, Marette A. Resveratrol inhibition of inducible nitric oxide synthase in skeletal muscle involves AMPK but not SIRT1. Am J Physiol Endocrinol Metab 2011; 301: E922-30.
    • (2011) Am J Physiol Endocrinol Metab , vol.301 , pp. E922-EE30
    • Centeno-Baez, C.1    Dallaire, P.2    Marette, A.3
  • 68
    • 80053091840 scopus 로고    scopus 로고
    • Resveratrol down-regulates interferon-y-inducible inflammatory genes in macrophages: Molecular mechanism via decreased STAT-1 activation
    • [68] Chung EY, Kim BH, Hong JT, et al. Resveratrol down-regulates interferon-y-inducible inflammatory genes in macrophages: molecular mechanism via decreased STAT-1 activation. J Nutr Biochem 2011; 22(10): 902-9.
    • (2011) J Nutr Biochem , vol.22 , Issue.10 , pp. 902-909
    • Chung, E.Y.1    Kim, B.H.2    Hong, J.T.3
  • 69
    • 84860865702 scopus 로고    scopus 로고
    • Resveratrol targeting of carcinogen-induced brain endothelial cell inflammation biomarkers MMP-9 and COX-2 is Sirt1-independent
    • [69] Annabi B, Lord-Dufour S, Vézina A, Béliveau R. Resveratrol targeting of carcinogen-induced brain endothelial cell inflammation biomarkers MMP-9 and COX-2 is Sirt1-independent. Drug Target Insights 2012; 6: 1-11.
    • (2012) Drug Target Insights , vol.6 , pp. 1-11
    • Annabi, B.1    Lord-Dufour, S.2    Vézina, A.3    Béliveau, R.4
  • 70
    • 0035793240 scopus 로고    scopus 로고
    • Resveratrol decreases hyperalgesia induced by carrageenan in the rat hind paw
    • [70] Gentilli M, Mazoit JX, Bouaziz H, et al. Resveratrol decreases hyperalgesia induced by carrageenan in the rat hind paw. Life Sci 2001; 68(11): 1317-21.
    • (2001) Life Sci , vol.68 , Issue.11 , pp. 1317-1321
    • Gentilli, M.1    Mazoit, J.X.2    Bouaziz, H.3
  • 71
    • 77956585215 scopus 로고    scopus 로고
    • An antiinflammatory and reactive oxygen species suppressive effects of an extract of Poly-gonum cuspidatum containing resveratrol
    • [71] Ghanim H, Sia CL, Abuaysheh S, et al. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Poly-gonum cuspidatum containing resveratrol. J Clin Endocrinol Metab 2010; 95: E1-E8.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. E1-E8
    • Ghanim, H.1    Sia, C.L.2    Abuaysheh, S.3
  • 72
    • 84865322408 scopus 로고    scopus 로고
    • Bioactive compounds with effects on inflammation markers in humans
    • [72] Rosa FT, Zulet MÁ, Marchini JS, Martínez JA. Bioactive compounds with effects on inflammation markers in humans. Int J Food Sci Nutr 2012; 63(6): 749-65.
    • (2012) Int J Food Sci Nutr , vol.63 , Issue.6 , pp. 749-765
    • Rosa, F.T.1    Zulet, M.2    Marchini, J.S.3    Martínez, J.A.4
  • 73
    • 0037063709 scopus 로고    scopus 로고
    • Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats
    • [73] Sharma M, Gupta YK. Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats. Life Sci 2002; 71(21): 2489-98.
    • (2002) Life Sci , vol.71 , Issue.21 , pp. 2489-2498
    • Sharma, M.1    Gupta, Y.K.2
  • 74
    • 33845917602 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats
    • [74] Kumar A, Naidu PS, Seghal N, Padi SS. Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. Pharmacology 2007; 79(1): 17-26.
    • (2007) Pharmacology , vol.79 , Issue.1 , pp. 17-26
    • Kumar, A.1    Naidu, P.S.2    Seghal, N.3    Padi, S.S.4
  • 75
    • 84863498111 scopus 로고    scopus 로고
    • Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease
    • [75] Chang J, Rimando A, Pallas M, et al. Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease. Neurobiol Aging 2012; 33(9): 2062-7.
    • (2012) Neurobiol Aging , vol.33 , Issue.9 , pp. 2062-2067
    • Chang, J.1    Rimando, A.2    Pallas, M.3
  • 76
    • 77955540457 scopus 로고    scopus 로고
    • Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
    • [76] Lu X, Ma L, Ruan L, et al. Resveratrol differentially modulates inflammatory responses of microglia and astrocytes J Neuroin-flammation 2010; 7: 46.
    • (2010) J Neuroin-Flammation , vol.7 , pp. 46
    • Lu, X.1    Ma, L.2    Ruan, L.3
  • 77
    • 38349190690 scopus 로고    scopus 로고
    • Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells
    • [77] Son YH, Jeong YT, Lee KA, et al. Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells. J Cardiovasc Pharmacol 2008; 51(1): 71-7.
    • (2008) J Cardiovasc Pharmacol , vol.51 , Issue.1 , pp. 71-77
    • Son, Y.H.1    Jeong, Y.T.2    Lee, K.A.3
  • 78
    • 77349084360 scopus 로고    scopus 로고
    • Naturally occurring phytochemicals for the prevention of Alzheimer's disease
    • [78] Kim J, Lee HJ, Lee KW. Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem 2010; 112(6): 1415-30.
    • (2010) J Neurochem , vol.112 , Issue.6 , pp. 1415-1430
    • Kim, J.1    Lee, H.J.2    Lee, K.W.3
  • 79
    • 84867385981 scopus 로고    scopus 로고
    • Autophagy, polyphenols and healthy ageing
    • [79] Pallauf K, Rimbach G. Autophagy, polyphenols and healthy ageing. Ageing Res Rev 2012; 12(1): 237-52.
    • (2012) Ageing Res Rev , vol.12 , Issue.1 , pp. 237-252
    • Pallauf, K.1    Rimbach, G.2
  • 80
    • 84862777943 scopus 로고    scopus 로고
    • An epigenetic blockade of cognitive functions in the neurodegenerating brain
    • [80] Gräff J, Rei D, Guan JS, et al. An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 2012; 483(7388): 222-6
    • (2012) Nature , vol.483 , Issue.7388 , pp. 222-226
    • Gräff, J.1    Rei, D.2    Guan, J.S.3
  • 81
    • 80054958546 scopus 로고    scopus 로고
    • The potential role of epigenetic responses to diet in ageing
    • [81] Ford D, Ions LJ, Alatawi F, Wakeling LA. The potential role of epigenetic responses to diet in ageing. Proc Nutr Soc 2011; 70(3): 374-84.
    • (2011) Proc Nutr Soc , vol.70 , Issue.3 , pp. 374-384
    • Ford, D.1    Ions, L.J.2    Alatawi, F.3    Wakeling, L.A.4
  • 82
    • 75949098771 scopus 로고    scopus 로고
    • Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?
    • [82] Wakeling LA, Ions LJ, Ford D. Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions? Age (Dordr) 2009; 31(4): 327-34.
    • (2009) Age (Dordr) , vol.31 , Issue.4 , pp. 327-334
    • Wakeling, L.A.1    Ions, L.J.2    Ford, D.3
  • 83
    • 2942705826 scopus 로고    scopus 로고
    • Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    • [83] Alarcón JM, Malleret G, Touzani K, et al. Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 2004; 42(6): 947-59.
    • (2004) Neuron , vol.42 , Issue.6 , pp. 947-959
    • Alarcón, J.M.1    Malleret, G.2    Touzani, K.3


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