Necdin regulates p53 acetylation via sirtuin1 to modulate DNA damage response in cortical neurons

Journal of Neuroscience

Volumn 28, Issue 35, 2008, Pages 8772-8784

  Hasegawa, Koichi ^a   Yoshikawa, Kazuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Acetylation; Apoptosis; DNA damage; Necdin; p53; Sirt1

Indexed keywords

CAMPTOTHECIN; HYDROGEN PEROXIDE; NECDIN; PROTEIN P53; SIRTUIN 1; SMALL INTERFERING RNA; NERVE PROTEIN; NUCLEAR PROTEIN; SIRT1 PROTEIN, MOUSE; SIRTUIN;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DEACETYLATION; DNA DAMAGE; FEMALE; FOREBRAIN; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; ANALYSIS OF VARIANCE; ANIMAL; CARCINOMA; CELL CULTURE; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; EMBRYO (ANATOMY); GENETIC TRANSFECTION; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; METHODOLOGY; MOUSE MUTANT; MUTATION; NERVE CELL; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; RNA INTERFERENCE;

ACETYLATION; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CARCINOMA; CELLS, CULTURED; DOWN-REGULATION; EMBRYO, MAMMALIAN; HUMANS; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; ORGAN CULTURE TECHNIQUES; PROSENCEPHALON; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIRTUINS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 52049096152     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3052-08.2008     Document Type: Article

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