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Volumn 31, Issue 4, 2009, Pages 327-341

Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?

Author keywords

Dietary restriction; DNA methylation; Epigenetics; Histone acetylation; Resveratrol; Sirt1

Indexed keywords

DNA; RESVERATROL; SIRTUIN; SIRTUIN 1;

EID: 75949098771     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-009-9104-5     Document Type: Review
Times cited : (57)

References (127)
  • 1
    • 34548634762 scopus 로고    scopus 로고
    • Vitamin D supplementation and total mortality: A meta-analysis of randomized controlled trials
    • 1:CAS:528:DC%2BD2sXhtFejt7jN 17846391
    • P Autier S Gandini 2007 Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials Arch Intern Med 167 1730 1777 1:CAS:528:DC%2BD2sXhtFejt7jN 17846391
    • (2007) Arch Intern Med , vol.167 , pp. 1730-1777
    • Autier, P.1    Gandini, S.2
  • 2
    • 0028219470 scopus 로고
    • Comparison between the effect of butyric acid and its prodrug pivaloyloxymethylbutyrate on histones hyperacetylation in an HL-60 leukemic cell line
    • 1:CAS:528:DyaK2cXkvF2itbs%3D 8119779
    • A Aviram Y Zimrah M Shaklai, et al. 1994 Comparison between the effect of butyric acid and its prodrug pivaloyloxymethylbutyrate on histones hyperacetylation in an HL-60 leukemic cell line Int J Cancer 56 906 909 1:CAS:528:DyaK2cXkvF2itbs%3D 8119779
    • (1994) Int J Cancer , vol.56 , pp. 906-909
    • Aviram, A.1    Zimrah, Y.2    Shaklai, M.3
  • 3
    • 48349110303 scopus 로고    scopus 로고
    • A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
    • 18523577
    • JL Barger T Kayo JM Vann, et al. 2008 A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice PLoS ONE 3 e2264 18523577
    • (2008) PLoS ONE , vol.3 , pp. 2264
    • Barger, J.L.1    Kayo, T.2    Vann, J.M.3
  • 4
    • 13944276264 scopus 로고    scopus 로고
    • Life extension in the dwarf mouse
    • 1:CAS:528:DC%2BD2MXivVaitrk%3D 15536017
    • A Bartke H Brown-Borg 2004 Life extension in the dwarf mouse Curr Top Dev Biol 63 189 225 1:CAS:528:DC%2BD2MXivVaitrk%3D 15536017
    • (2004) Curr Top Dev Biol , vol.63 , pp. 189-225
    • Bartke, A.1    Brown-Borg, H.2
  • 5
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • 1:CAS:528:DC%2BD28Xht1Sgtb3I 17086191
    • JA Baur KJ Pearson NL Price, et al. 2006 Resveratrol improves health and survival of mice on a high-calorie diet Nature 444 337 342 1:CAS:528: DC%2BD28Xht1Sgtb3I 17086191
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 6
    • 0019908610 scopus 로고
    • Gestational zinc deprivation in mice: Persistence of immunodeficiency for three generations
    • 1:CAS:528:DyaL38XlvVSks7w%3D 7123244
    • RS Beach ME Gershwin LS Hurley 1982 Gestational zinc deprivation in mice: persistence of immunodeficiency for three generations Science 218 469 471 1:CAS:528:DyaL38XlvVSks7w%3D 7123244
    • (1982) Science , vol.218 , pp. 469-471
    • Beach, R.S.1    Gershwin, M.E.2    Hurley, L.S.3
  • 7
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
    • 1:CAS:528:DC%2BD2sXhtFOksL7I 17909538
    • NA Bishop L Guarente 2007 Genetic links between diet and lifespan: shared mechanisms from yeast to humans Nat Rev Genet 8 835 844 1:CAS:528: DC%2BD2sXhtFOksL7I 17909538
    • (2007) Nat Rev Genet , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 9
    • 11244313061 scopus 로고    scopus 로고
    • Homocysteine associated genomic DNA hypermethylation in patients with chronic alcoholism
    • 1:STN:280:DC%2BD2crptFKjsg%3D%3D 15565495
    • D Bonsch B Lenz U Reulbach, et al. 2004 Homocysteine associated genomic DNA hypermethylation in patients with chronic alcoholism J Neural Transm 111 1611 1616 1:STN:280:DC%2BD2crptFKjsg%3D%3D 15565495
    • (2004) J Neural Transm , vol.111 , pp. 1611-1616
    • Bonsch, D.1    Lenz, B.2    Reulbach, U.3
  • 10
    • 33244486764 scopus 로고    scopus 로고
    • Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
    • 16366736
    • L Bordone MC Motta F Picard, et al. 2006 Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells PLoS Biol 4 e31 16366736
    • (2006) PLoS Biol , vol.4 , pp. 31
    • Bordone, L.1    Motta, M.C.2    Picard, F.3
  • 11
    • 36248975293 scopus 로고    scopus 로고
    • SIRT1 transgenic mice show phenotypes resembling calorie restriction
    • 1:CAS:528:DC%2BD2sXhsVeksbbJ 17877786
    • L Bordone D Cohen A Robinson, et al. 2007 SIRT1 transgenic mice show phenotypes resembling calorie restriction Aging Cell 6 759 767 1:CAS:528:DC%2BD2sXhsVeksbbJ 17877786
    • (2007) Aging Cell , vol.6 , pp. 759-767
    • Bordone, L.1    Cohen, D.2    Robinson, A.3
  • 12
    • 20444444649 scopus 로고    scopus 로고
    • Mechanism of human SIRT1 activation by resveratrol
    • 1:CAS:528:DC%2BD2MXjsFOgtb8%3D 15749705
    • MT Borra BC Smith JM Denu 2005 Mechanism of human SIRT1 activation by resveratrol J Biol Chem 280 17187 17195 1:CAS:528:DC%2BD2MXjsFOgtb8%3D 15749705
    • (2005) J Biol Chem , vol.280 , pp. 17187-17195
    • Borra, M.T.1    Smith, B.C.2    Denu, J.M.3
  • 13
    • 34047258298 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations
    • 1:CAS:528:DC%2BD2sXjvVSitbY%3D 17313703
    • GC Burdge J Slater-Jefferies C Torrens, et al. 2007 Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations Br J Nutr 97 435 439 1:CAS:528:DC%2BD2sXjvVSitbY%3D 17313703
    • (2007) Br J Nutr , vol.97 , pp. 435-439
    • Burdge, G.C.1    Slater-Jefferies, J.2    Torrens, C.3
  • 14
    • 0141839825 scopus 로고    scopus 로고
    • Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
    • 1:CAS:528:DC%2BD3sXmvFeqs7s%3D 14577574
    • MA Casillas Jr N Lopatina LG Andrews, et al. 2003 Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically- transformed human fibroblasts Mol Cell Biochem 252 33 43 1:CAS:528: DC%2BD3sXmvFeqs7s%3D 14577574
    • (2003) Mol Cell Biochem , vol.252 , pp. 33-43
    • Casillas Jr, M.A.1    Lopatina, N.2    Andrews, L.G.3
  • 15
    • 0018840155 scopus 로고
    • Alteration of higher order structure of rat liver chromatin by dietary composition
    • 1:CAS:528:DyaL3cXht1OnsL8%3D 7354375
    • CE Castro JS Sevall 1980 Alteration of higher order structure of rat liver chromatin by dietary composition J Nutr 110 105 116 1:CAS:528: DyaL3cXht1OnsL8%3D 7354375
    • (1980) J Nutr , vol.110 , pp. 105-116
    • Castro, C.E.1    Sevall, J.S.2
  • 16
    • 33846583673 scopus 로고    scopus 로고
    • SIR2: A potential target for calorie restriction mimetics
    • 1:CAS:528:DC%2BD2sXhtlSnsro%3D 17207661
    • D Chen L Guarente 2007 SIR2: a potential target for calorie restriction mimetics Trends Mol Med 13 64 71 1:CAS:528:DC%2BD2sXhtlSnsro%3D 17207661
    • (2007) Trends Mol Med , vol.13 , pp. 64-71
    • Chen, D.1    Guarente, L.2
  • 17
    • 46249100836 scopus 로고    scopus 로고
    • Tissue-specific regulation of SIRT1 by calorie restriction
    • 1:CAS:528:DC%2BD1cXot1egu78%3D 18550784
    • D Chen J Bruno E Easlon, et al. 2008 Tissue-specific regulation of SIRT1 by calorie restriction Genes Dev 22 1753 1757 1:CAS:528:DC%2BD1cXot1egu78%3D 18550784
    • (2008) Genes Dev , vol.22 , pp. 1753-1757
    • Chen, D.1    Bruno, J.2    Easlon, E.3
  • 18
    • 0141814680 scopus 로고    scopus 로고
    • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
    • 1:CAS:528:DC%2BD3sXnslyntrc%3D 12960381
    • HL Cheng R Mostoslavsky S Saito, et al. 2003 Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice Proc Natl Acad Sci USA 100 10794 10799 1:CAS:528:DC%2BD3sXnslyntrc%3D 12960381
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10794-10799
    • Cheng, H.L.1    Mostoslavsky, R.2    Saito, S.3
  • 19
    • 0032729779 scopus 로고    scopus 로고
    • Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon
    • 1:CAS:528:DyaK1MXmvFaitrk%3D 10539767
    • SW Choi F Stickel HW Baik, et al. 1999 Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon J Nutr 129 1945 1950 1:CAS:528:DyaK1MXmvFaitrk%3D 10539767
    • (1999) J Nutr , vol.129 , pp. 1945-1950
    • Choi, S.W.1    Stickel, F.2    Baik, H.W.3
  • 20
    • 33947710793 scopus 로고    scopus 로고
    • Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
    • 17341128
    • AE Civitarese S Carling LK Heilbronn, et al. 2007 Calorie restriction increases muscle mitochondrial biogenesis in healthy humans PLoS Med 4 e76 17341128
    • (2007) PLoS Med , vol.4 , pp. 76
    • Civitarese, A.E.1    Carling, S.2    Heilbronn, L.K.3
  • 21
    • 3142740860 scopus 로고    scopus 로고
    • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
    • 1:CAS:528:DC%2BD2cXls1egtrs%3D 15205477
    • HY Cohen C Miller KJ Bitterman, et al. 2004 Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase Science 305 390 392 1:CAS:528:DC%2BD2cXls1egtrs%3D 15205477
    • (2004) Science , vol.305 , pp. 390-392
    • Cohen, H.Y.1    Miller, C.2    Bitterman, K.J.3
  • 22
    • 0032822001 scopus 로고    scopus 로고
    • Body fat distribution with long-term dietary restriction in adult male rhesus macaques
    • 1:STN:280:DyaK1MzovFamtA%3D%3D 10462160
    • RJ Colman JJ Ramsey EB Roecker, et al. 1999 Body fat distribution with long-term dietary restriction in adult male rhesus macaques J Gerontol A Biol Sci Med Sci 54 B283 B290 1:STN:280:DyaK1MzovFamtA%3D%3D 10462160
    • (1999) J Gerontol A Biol Sci Med Sci , vol.54
    • Colman, R.J.1    Ramsey, J.J.2    Roecker, E.B.3
  • 23
    • 31544436888 scopus 로고    scopus 로고
    • Dietary HDAC inhibitors: Time to rethink weak ligands in cancer chemoprevention?
    • 1:CAS:528:DC%2BD28XmslyrtQ%3D%3D 16267097
    • RH Dashwood MC Myzak E Ho 2006 Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis 27 344 349 1:CAS:528:DC%2BD28XmslyrtQ%3D%3D 16267097
    • (2006) Carcinogenesis , vol.27 , pp. 344-349
    • Dashwood, R.H.1    Myzak, M.C.2    Ho, E.3
  • 24
    • 0036170179 scopus 로고    scopus 로고
    • Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells
    • 1:CAS:528:DC%2BD38XhtFGnsrY%3D 11823593
    • CD Davis EO Uthus 2002 Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells J Nutr 132 292 297 1:CAS:528:DC%2BD38XhtFGnsrY%3D 11823593
    • (2002) J Nutr , vol.132 , pp. 292-297
    • Davis, C.D.1    Uthus, E.O.2
  • 25
    • 0041417403 scopus 로고    scopus 로고
    • Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats
    • 1:CAS:528:DC%2BD3sXntlaks7c%3D 12949386
    • CD Davis EO Uthus 2003 Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats J Nutr 133 2907 2914 1:CAS:528: DC%2BD3sXntlaks7c%3D 12949386
    • (2003) J Nutr , vol.133 , pp. 2907-2914
    • Davis, C.D.1    Uthus, E.O.2
  • 26
    • 0034533186 scopus 로고    scopus 로고
    • Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon
    • 1:CAS:528:DC%2BD3cXptVKmtLg%3D 11110844
    • CD Davis EO Uthus JW Finley 2000 Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon J Nutr 130 2903 2909 1:CAS:528:DC%2BD3cXptVKmtLg%3D 11110844
    • (2000) J Nutr , vol.130 , pp. 2903-2909
    • Davis, C.D.1    Uthus, E.O.2    Finley, J.W.3
  • 27
    • 45549101782 scopus 로고    scopus 로고
    • Cell divisions and mammalian aging: Integrative biology insights from genes that regulate longevity
    • 18478536
    • JP de Magalhaes RG Faragher 2008 Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity Bioessays 30 567 578 18478536
    • (2008) Bioessays , vol.30 , pp. 567-578
    • De Magalhaes, J.P.1    Faragher, R.G.2
  • 28
    • 1842732174 scopus 로고    scopus 로고
    • Temporal linkage between the phenotypic and genomic responses to caloric restriction
    • 1:CAS:528:DC%2BD2cXjsVagurg%3D 15044709
    • JM Dhahbi HJ Kim PL Mote, et al. 2004 Temporal linkage between the phenotypic and genomic responses to caloric restriction Proc Natl Acad Sci USA 101 5524 5529 1:CAS:528:DC%2BD2cXjsVagurg%3D 15044709
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 5524-5529
    • Dhahbi, J.M.1    Kim, H.J.2    Mote, P.L.3
  • 29
    • 0038527642 scopus 로고    scopus 로고
    • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
    • 11834837
    • L Di Croce VA Raker M Corsaro, et al. 2002 Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor Science 295 1079 1082 11834837
    • (2002) Science , vol.295 , pp. 1079-1082
    • Di Croce, L.1    Raker, V.A.2    Corsaro, M.3
  • 30
    • 33645633542 scopus 로고    scopus 로고
    • Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
    • 1:CAS:528:DC%2BD28Xktlensrs%3D 16581547
    • DC Dolinoy JR Weidman RA Waterland, et al. 2006 Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome Environ Health Perspect 114 567 572 1:CAS:528:DC%2BD28Xktlensrs%3D 16581547
    • (2006) Environ Health Perspect , vol.114 , pp. 567-572
    • Dolinoy, D.C.1    Weidman, J.R.2    Waterland, R.A.3
  • 31
    • 34548715144 scopus 로고    scopus 로고
    • Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
    • 1:CAS:528:DC%2BD2sXpt1GhsL8%3D 17670942
    • DC Dolinoy D Huang RL Jirtle 2007 Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development Proc Natl Acad Sci USA 104 13056 13061 1:CAS:528:DC%2BD2sXpt1GhsL8%3D 17670942
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13056-13061
    • Dolinoy, D.C.1    Huang, D.2    Jirtle, R.L.3
  • 32
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • 1:CAS:528:DC%2BD3sXktlektb8%3D 12702868
    • A Eden F Gaudet A Waghmare, et al. 2003 Chromosomal instability and tumors promoted by DNA hypomethylation Science 300 455 1:CAS:528: DC%2BD3sXktlektb8%3D 12702868
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3
  • 33
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • 1:CAS:528:DC%2BD2MXhtVKiurjI 16203797
    • MZ Fang D Chen Y Sun, et al. 2005 Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy Clin Cancer Res 11 7033 7041 1:CAS:528:DC%2BD2MXhtVKiurjI 16203797
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3
  • 34
    • 33745215673 scopus 로고    scopus 로고
    • Mechanisms by which poor early growth programs type-2 diabetes, obesity and the metabolic syndrome
    • 1:CAS:528:DC%2BD28Xmt1Oqtrs%3D 16782139
    • DS Fernandez-Twinn SE Ozanne, et al. 2006 Mechanisms by which poor early growth programs type-2 diabetes, obesity and the metabolic syndrome Physiol Behav 88 234 243 1:CAS:528:DC%2BD28Xmt1Oqtrs%3D 16782139
    • (2006) Physiol Behav , vol.88 , pp. 234-243
    • Fernandez-Twinn, D.S.1    Ozanne, S.E.2
  • 35
    • 33847764645 scopus 로고    scopus 로고
    • Aging, adiposity, and calorie restriction
    • 1:CAS:528:DC%2BD2sXisFKmu78%3D 17341713
    • L Fontana S Klein 2007 Aging, adiposity, and calorie restriction JAMA 297 986 994 1:CAS:528:DC%2BD2sXisFKmu78%3D 17341713
    • (2007) JAMA , vol.297 , pp. 986-994
    • Fontana, L.1    Klein, S.2
  • 36
    • 2342647592 scopus 로고    scopus 로고
    • Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
    • 1:CAS:528:DC%2BD2cXjvVyiu7c%3D 15096581
    • L Fontana TE Meyer S Klein, et al. 2004 Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans Proc Natl Acad Sci USA 101 6659 6663 1:CAS:528:DC%2BD2cXjvVyiu7c%3D 15096581
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6659-6663
    • Fontana, L.1    Meyer, T.E.2    Klein, S.3
  • 37
    • 23044514669 scopus 로고    scopus 로고
    • Epigenetic differences arise during the lifetime of monozygotic twins
    • 1:CAS:528:DC%2BD2MXntVSiur0%3D 16009939
    • MF Fraga E Ballestar MF Paz, et al. 2005 Epigenetic differences arise during the lifetime of monozygotic twins Proc Natl Acad Sci USA 102 10604 10609 1:CAS:528:DC%2BD2MXntVSiur0%3D 16009939
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10604-10609
    • Fraga, M.F.1    Ballestar, E.2    Paz, M.F.3
  • 38
    • 34249683635 scopus 로고    scopus 로고
    • Cross-talk between aging and cancer: The epigenetic language
    • 1:CAS:528:DC%2BD2sXlslOisLY%3D 17460165
    • MF Fraga R Agrelo M Esteller 2007 Cross-talk between aging and cancer: the epigenetic language Ann N Y Acad Sci 1100 60 74 1:CAS:528: DC%2BD2sXlslOisLY%3D 17460165
    • (2007) Ann N y Acad Sci , vol.1100 , pp. 60-74
    • Fraga, M.F.1    Agrelo, R.2    Esteller, M.3
  • 39
    • 0242584449 scopus 로고    scopus 로고
    • Induction of tumors in mice by genomic hypomethylation
    • 1:CAS:528:DC%2BD3sXivFyms7Y%3D 12702876
    • F Gaudet JG Hodgson A Eden, et al. 2003 Induction of tumors in mice by genomic hypomethylation Science 300 489 492 1:CAS:528:DC%2BD3sXivFyms7Y%3D 12702876
    • (2003) Science , vol.300 , pp. 489-492
    • Gaudet, F.1    Hodgson, J.G.2    Eden, A.3
  • 40
    • 33645702660 scopus 로고    scopus 로고
    • DNA methyltransferases control telomere length and telomere recombination in mammalian cells
    • 1:CAS:528:DC%2BD28Xjt12qs7g%3D 16565708
    • S Gonzalo I Jaco MF Fraga, et al. 2006 DNA methyltransferases control telomere length and telomere recombination in mammalian cells Nat Cell Biol 8 416 424 1:CAS:528:DC%2BD28Xjt12qs7g%3D 16565708
    • (2006) Nat Cell Biol , vol.8 , pp. 416-424
    • Gonzalo, S.1    Jaco, I.2    Fraga, M.F.3
  • 41
    • 0034791231 scopus 로고    scopus 로고
    • Dietary restriction and glucose regulation in aging rhesus monkeys: A follow-up report at 8.5 yr
    • 1:CAS:528:DC%2BD3MXnsFSksrg%3D 11551852
    • TA Gresl RJ Colman EB Roecker, et al. 2001 Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr Am J Physiol Endocrinol Metab 281 E757 E765 1:CAS:528:DC%2BD3MXnsFSksrg%3D 11551852
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Gresl, T.A.1    Colman, R.J.2    Roecker, E.B.3
  • 42
    • 48249091971 scopus 로고    scopus 로고
    • Sirtuins in aging and disease
    • 1:CAS:528:DC%2BD1cXnvVWltrg%3D 18419308
    • L Guarente 2007 Sirtuins in aging and disease Cold Spring Harb Symp Quant Biol 72 483 488 1:CAS:528:DC%2BD1cXnvVWltrg%3D 18419308
    • (2007) Cold Spring Harb Symp Quant Biol , vol.72 , pp. 483-488
    • Guarente, L.1
  • 43
    • 13944253348 scopus 로고    scopus 로고
    • Calorie restriction-the SIR2 connection
    • 1:CAS:528:DC%2BD2MXitVWnuro%3D 15734680
    • L Guarente F Picard 2005 Calorie restriction-the SIR2 connection Cell 120 473 482 1:CAS:528:DC%2BD2MXitVWnuro%3D 15734680
    • (2005) Cell , vol.120 , pp. 473-482
    • Guarente, L.1    Picard, F.2
  • 44
    • 39149098441 scopus 로고    scopus 로고
    • H1 histone subtype constitution and phosphorylation state of the ageing cell system of human peripheral blood lymphocytes
    • 1:CAS:528:DC%2BD1cXitVOms7g%3D 18234461
    • N Happel D Doenecke KE Sekeri-Pataryas, et al. 2008 H1 histone subtype constitution and phosphorylation state of the ageing cell system of human peripheral blood lymphocytes Exp Gerontol 43 184 199 1:CAS:528: DC%2BD1cXitVOms7g%3D 18234461
    • (2008) Exp Gerontol , vol.43 , pp. 184-199
    • Happel, N.1    Doenecke, D.2    Sekeri-Pataryas, K.E.3
  • 45
    • 0001001689 scopus 로고
    • Effects of food restriction on aging: Separation of food intake and adiposity
    • 1:STN:280:DyaL2c7ntVeqtQ%3D%3D 6608731
    • DE Harrison JR Archer CM Astle 1984 Effects of food restriction on aging: separation of food intake and adiposity Proc Natl Acad Sci USA 81 1835 1838 1:STN:280:DyaL2c7ntVeqtQ%3D%3D 6608731
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 1835-1838
    • Harrison, D.E.1    Archer, J.R.2    Astle, C.M.3
  • 46
    • 0027745794 scopus 로고
    • Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro
    • 1:CAS:528:DyaK2cXhs1ansro%3D 7507563
    • BS Hass RW Hart MH Lu, et al. 1993 Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro Mutat Res 295 281 289 1:CAS:528:DyaK2cXhs1ansro%3D 7507563
    • (1993) Mutat Res , vol.295 , pp. 281-289
    • Hass, B.S.1    Hart, R.W.2    Lu, M.H.3
  • 48
    • 1442314701 scopus 로고    scopus 로고
    • Adipose tissue energy metabolism: Altered gene expression profile of mice subjected to long-term caloric restriction
    • 1:CAS:528:DC%2BD2cXht1GitLw%3D 14688200
    • Y Higami TD Pugh GP Page, et al. 2004 Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction Faseb J 18 415 417 1:CAS:528:DC%2BD2cXht1GitLw%3D 14688200
    • (2004) Faseb J , vol.18 , pp. 415-417
    • Higami, Y.1    Pugh, T.D.2    Page, G.P.3
  • 49
    • 0031058447 scopus 로고    scopus 로고
    • Mortality rate and longevity of food-restricted exercising male rats: A reevaluation
    • 1:STN:280:DyaK2s3gt1Wruw%3D%3D 9049716
    • JO Holloszy 1997 Mortality rate and longevity of food-restricted exercising male rats: a reevaluation J Appl Physiol 82 399 403 1:STN:280:DyaK2s3gt1Wruw%3D%3D 9049716
    • (1997) J Appl Physiol , vol.82 , pp. 399-403
    • Holloszy, J.O.1
  • 50
    • 0022410244 scopus 로고
    • Effect of voluntary exercise on longevity of rats
    • 1:STN:280:DyaL28%2FjtlCisQ%3D%3D 4055572
    • JO Holloszy EK Smith M Vining, et al. 1985 Effect of voluntary exercise on longevity of rats J Appl Physiol 59 826 831 1:STN:280:DyaL28%2FjtlCisQ%3D%3D 4055572
    • (1985) J Appl Physiol , vol.59 , pp. 826-831
    • Holloszy, J.O.1    Smith, E.K.2    Vining, M.3
  • 51
    • 0029935604 scopus 로고    scopus 로고
    • Replicative senescence: Considerations relating to the stability of heterochromatin domains
    • 1:STN:280:DyaK283mtVKrsw%3D%3D 8706797
    • BH Howard 1996 Replicative senescence: considerations relating to the stability of heterochromatin domains Exp Gerontol 31 281 293 1:STN:280:DyaK283mtVKrsw%3D%3D 8706797
    • (1996) Exp Gerontol , vol.31 , pp. 281-293
    • Howard, B.H.1
  • 52
    • 20444457163 scopus 로고    scopus 로고
    • Promotor hypermethylation of p14ARF is a key alteration for progression of oral squamous cell carcinoma
    • 1:CAS:528:DC%2BD2MXlsFGgsbo%3D 15975525
    • E Ishida M Nakamura M Ikuta, et al. 2005 Promotor hypermethylation of p14ARF is a key alteration for progression of oral squamous cell carcinoma Oral Oncol 41 614 622 1:CAS:528:DC%2BD2MXlsFGgsbo%3D 15975525
    • (2005) Oral Oncol , vol.41 , pp. 614-622
    • Ishida, E.1    Nakamura, M.2    Ikuta, M.3
  • 53
    • 0028001087 scopus 로고
    • Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
    • 1:CAS:528:DyaK2cXlsFSntb0%3D 7951326
    • JP Issa YL Ottaviano P Celano, et al. 1994 Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon Nat Genet 7 536 540 1:CAS:528:DyaK2cXlsFSntb0%3D 7951326
    • (1994) Nat Genet , vol.7 , pp. 536-540
    • Issa, J.P.1    Ottaviano, Y.L.2    Celano, P.3
  • 54
    • 0035328527 scopus 로고    scopus 로고
    • Accelerated age-related CpG island methylation in ulcerative colitis
    • 1:CAS:528:DC%2BD3MXjsFCgtLw%3D 11325821
    • JP Issa N Ahuja M Toyota, et al. 2001 Accelerated age-related CpG island methylation in ulcerative colitis Cancer Res 61 3573 3577 1:CAS:528: DC%2BD3MXjsFCgtLw%3D 11325821
    • (2001) Cancer Res , vol.61 , pp. 3573-3577
    • Issa, J.P.1    Ahuja, N.2    Toyota, M.3
  • 55
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • 1:CAS:528:DyaK1cXktlajsL4%3D 9649607
    • RA Jacob DM Gretz PC Taylor, et al. 1998 Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women J Nutr 128 1204 1212 1:CAS:528:DyaK1cXktlajsL4%3D 9649607
    • (1998) J Nutr , vol.128 , pp. 1204-1212
    • Jacob, R.A.1    Gretz, D.M.2    Taylor, P.C.3
  • 56
    • 0017841253 scopus 로고
    • Impact of Westernization on the nutrition of Japanese: Changes in physique, cancer, longevity and centenarians
    • 1:CAS:528:DyaE1cXksFylsLk%3D 674107
    • Y Kagawa 1978 Impact of Westernization on the nutrition of Japanese: changes in physique, cancer, longevity and centenarians Prev Med 7 205 217 1:CAS:528:DyaE1cXksFylsLk%3D 674107
    • (1978) Prev Med , vol.7 , pp. 205-217
    • Kagawa, Y.1
  • 57
    • 0031459719 scopus 로고    scopus 로고
    • Adult-onset energy restriction of rhesus monkeys attenuates oxidative stress-induced cytokine expression by peripheral blood mononuclear cells
    • 1:CAS:528:DyaK1cXislSksw%3D%3D 9405577
    • MJ Kim JM Aiken T Havighurst, et al. 1997 Adult-onset energy restriction of rhesus monkeys attenuates oxidative stress-induced cytokine expression by peripheral blood mononuclear cells J Nutr 127 2293 2301 1:CAS:528: DyaK1cXislSksw%3D%3D 9405577
    • (1997) J Nutr , vol.127 , pp. 2293-2301
    • Kim, M.J.1    Aiken, J.M.2    Havighurst, T.3
  • 58
    • 33845647686 scopus 로고    scopus 로고
    • Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence
    • 1:CAS:528:DC%2BD2sXht1Squg%3D%3D 17110088
    • J Kim JY Kim KS Song, et al. 2007 Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence Biochim Biophys Acta 1772 72 80 1:CAS:528:DC%2BD2sXht1Squg%3D%3D 17110088
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 72-80
    • Kim, J.1    Kim, J.Y.2    Song, K.S.3
  • 59
    • 0018644035 scopus 로고
    • MAR1-a regulator of the HMa and HMalpha loci in Saccharomyces cerevisiae
    • 17248968
    • AJ Klar S Fogel K Macleod 1979 MAR1-a regulator of the HMa and HMalpha loci in Saccharomyces cerevisiae Genetics 93 37 50 17248968
    • (1979) Genetics , vol.93 , pp. 37-50
    • Klar, A.J.1    Fogel, S.2    MacLeod, K.3
  • 60
    • 34447128753 scopus 로고    scopus 로고
    • Age-related DNA methylation changes in normal human prostate tissues
    • 1:CAS:528:DC%2BD2sXntFymsbs%3D 17606710
    • B Kwabi-Addo W Chung L Shen, et al. 2007 Age-related DNA methylation changes in normal human prostate tissues Clin Cancer Res 13 3796 3802 1:CAS:528:DC%2BD2sXntFymsbs%3D 17606710
    • (2007) Clin Cancer Res , vol.13 , pp. 3796-3802
    • Kwabi-Addo, B.1    Chung, W.2    Shen, L.3
  • 61
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
    • 1:CAS:528:DC%2BD2sXhs1egsQ%3D%3D 17112576
    • M Lagouge C Argmann Z Gerhart-Hines, et al. 2006 Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha Cell 127 1109 1122 1:CAS:528:DC%2BD2sXhs1egsQ%3D%3D 17112576
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3
  • 62
    • 0029994960 scopus 로고    scopus 로고
    • Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents
    • 1:CAS:528:DyaK28XivVKqsrk%3D 8633033
    • MA Lane DJ Baer WV Rumpler, et al. 1996 Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents Proc Natl Acad Sci USA 93 4159 4164 1:CAS:528:DyaK28XivVKqsrk%3D 8633033
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4159-4164
    • Lane, M.A.1    Baer, D.J.2    Rumpler, W.V.3
  • 63
    • 0033377625 scopus 로고    scopus 로고
    • Calorie restriction in nonhuman primates: Effects on diabetes and cardiovascular disease risk
    • 1:CAS:528:DC%2BD3cXhtFyrsg%3D%3D 10630589
    • MA Lane DK Ingram GS Roth 1999 Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk Toxicol Sci 52 41 48 1:CAS:528:DC%2BD3cXhtFyrsg%3D%3D 10630589
    • (1999) Toxicol Sci , vol.52 , pp. 41-48
    • Lane, M.A.1    Ingram, D.K.2    Roth, G.S.3
  • 64
    • 0037093346 scopus 로고    scopus 로고
    • Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
    • 1:CAS:528:DC%2BD38XktFChu7c%3D 12006491
    • E Langley M Pearson M Faretta, et al. 2002 Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence EMBO J 21 2383 2396 1:CAS:528:DC%2BD38XktFChu7c%3D 12006491
    • (2002) EMBO J , vol.21 , pp. 2383-2396
    • Langley, E.1    Pearson, M.2    Faretta, M.3
  • 65
    • 25144507259 scopus 로고    scopus 로고
    • Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
    • 1:CAS:528:DC%2BD2MXhtVyhu7bM 16037419
    • WJ Lee JY Shim BT Zhu 2005 Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids Mol Pharmacol 68 1018 1030 1:CAS:528:DC%2BD2MXhtVyhu7bM 16037419
    • (2005) Mol Pharmacol , vol.68 , pp. 1018-1030
    • Lee, W.J.1    Shim, J.Y.2    Zhu, B.T.3
  • 66
    • 20444411948 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
    • 1:CAS:528:DC%2BD2MXltFaiu7Y%3D 15930441
    • KA Lillycrop ES Phillips AA Jackson, et al. 2005 Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring J Nutr 135 1382 1386 1:CAS:528:DC%2BD2MXltFaiu7Y%3D 15930441
    • (2005) J Nutr , vol.135 , pp. 1382-1386
    • Lillycrop, K.A.1    Phillips, E.S.2    Jackson, A.A.3
  • 67
    • 34247514180 scopus 로고    scopus 로고
    • Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications
    • 1:CAS:528:DC%2BD2sXnt1Gisrs%3D 17433129
    • KA Lillycrop JL Slater-Jefferies MA Hanson, et al. 2007 Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications Br J Nutr 97 1064 1073 1:CAS:528:DC%2BD2sXnt1Gisrs%3D 17433129
    • (2007) Br J Nutr , vol.97 , pp. 1064-1073
    • Lillycrop, K.A.1    Slater-Jefferies, J.L.2    Hanson, M.A.3
  • 69
    • 0035679346 scopus 로고    scopus 로고
    • Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts
    • 11787061
    • N Lopatina JF Haskell LG Andrews, et al. 2002 Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts J Cell Biochem 84 324 334 11787061
    • (2002) J Cell Biochem , vol.84 , pp. 324-334
    • Lopatina, N.1    Haskell, J.F.2    Andrews, L.G.3
  • 70
    • 49649128985 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and healthy aging
    • 1:CAS:528:DC%2BD1cXhtVart7rJ 18662766
    • G Lopez-Lluch PM Irusta P Navas, et al. 2008 Mitochondrial biogenesis and healthy aging Exp Gerontol 43 813 819 1:CAS:528:DC%2BD1cXhtVart7rJ 18662766
    • (2008) Exp Gerontol , vol.43 , pp. 813-819
    • Lopez-Lluch, G.1    Irusta, P.M.2    Navas, P.3
  • 71
    • 1242306276 scopus 로고    scopus 로고
    • Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice
    • 1:STN:280:DC%2BD2c%2FotVGjsA%3D%3D 14969733
    • CR Marutha Ravindran MK Ticku 2004 Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice Brain Res Mol Brain Res 121 19 27 1:STN:280:DC%2BD2c%2FotVGjsA%3D%3D 14969733
    • (2004) Brain Res Mol Brain Res , vol.121 , pp. 19-27
    • Marutha Ravindran, C.R.1    Ticku, M.K.2
  • 72
    • 68949146690 scopus 로고    scopus 로고
    • Nutrition, epigenetics and aging
    • Friso S, Choi SW (eds) CRC, Boca Raton
    • Mathers JC, Ford D (2009) Nutrition, epigenetics and aging. In: Friso S, Choi SW (eds) Nutrients and epigenetics. CRC, Boca Raton, pp 175-206
    • (2009) Nutrients and Epigenetics , pp. 175-206
    • Mathers, J.C.1    Ford, D.2
  • 73
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • 1:CAS:528:DyaA2MXmtFCgug%3D%3D
    • CM McCay MF Crowell LA Maynard 1935 The effect of retarded growth upon the length of life span and upon the ultimate body size J Nutr 10 63 79 1:CAS:528:DyaA2MXmtFCgug%3D%3D
    • (1935) J Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 74
    • 33845898766 scopus 로고    scopus 로고
    • Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates
    • 1:CAS:528:DC%2BD2sXhs1yrsw%3D%3D 17159149
    • I Messaoudi J Warner M Fischer, et al. 2006 Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates Proc Natl Acad Sci USA 103 19448 19453 1:CAS:528:DC%2BD2sXhs1yrsw%3D%3D 17159149
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19448-19453
    • Messaoudi, I.1    Warner, J.2    Fischer, M.3
  • 75
    • 56849113103 scopus 로고    scopus 로고
    • Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates
    • 1:CAS:528:DC%2BD1cXhsFemt77L 19032694
    • I Messaoudi M Fischer J Warner, et al. 2008 Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates Aging Cell 7 908 919 1:CAS:528:DC%2BD1cXhsFemt77L 19032694
    • (2008) Aging Cell , vol.7 , pp. 908-919
    • Messaoudi, I.1    Fischer, M.2    Warner, J.3
  • 76
    • 30344435943 scopus 로고    scopus 로고
    • Long-term caloric restriction ameliorates the decline in diastolic function in humans
    • 1:CAS:528:DC%2BD28XksFCntQ%3D%3D 16412867
    • TE Meyer SJ Kovacs AA Ehsani, et al. 2006 Long-term caloric restriction ameliorates the decline in diastolic function in humans J Am Coll Cardiol 47 398 402 1:CAS:528:DC%2BD28XksFCntQ%3D%3D 16412867
    • (2006) J Am Coll Cardiol , vol.47 , pp. 398-402
    • Meyer, T.E.1    Kovacs, S.J.2    Ehsani, A.A.3
  • 77
    • 0028245837 scopus 로고
    • Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage
    • 1:CAS:528:DyaK2cXlsFSgtL4%3D 7926745
    • EJ Michaud MJ van Vugt SJ Bultman, et al. 1994 Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage Genes Dev 8 1463 1472 1:CAS:528: DyaK2cXlsFSgtL4%3D 7926745
    • (1994) Genes Dev , vol.8 , pp. 1463-1472
    • Michaud, E.J.1    Van Vugt, M.J.2    Bultman, S.J.3
  • 78
    • 0027533513 scopus 로고
    • Effects of energy restriction on age-associated changes of DNA methylation in mouse liver
    • 1:CAS:528:DyaK3sXhs1yitb8%3D 7680421
    • Y Miyamura R Tawa A Koizumi, et al. 1993 Effects of energy restriction on age-associated changes of DNA methylation in mouse liver Mutat Res 295 63 69 1:CAS:528:DyaK3sXhs1yitb8%3D 7680421
    • (1993) Mutat Res , vol.295 , pp. 63-69
    • Miyamura, Y.1    Tawa, R.2    Koizumi, A.3
  • 79
    • 0036949793 scopus 로고    scopus 로고
    • Inhibitory effects of beta-carotene and vitamin a during the progression phase of hepatocarcinogenesis involve inhibition of cell proliferation but not alterations in DNA methylation
    • 1:CAS:528:DC%2BD3sXjtFGisbs%3D 12672634
    • FS Moreno T SW MM Naves, et al. 2002 Inhibitory effects of beta-carotene and vitamin a during the progression phase of hepatocarcinogenesis involve inhibition of cell proliferation but not alterations in DNA methylation Nutr Cancer 44 80 88 1:CAS:528:DC%2BD3sXjtFGisbs%3D 12672634
    • (2002) Nutr Cancer , vol.44 , pp. 80-88
    • Moreno, F.S.1    Sw, T.2    Naves, M.M.3
  • 80
    • 33744990610 scopus 로고    scopus 로고
    • Dietary agents as histone deacetylase inhibitors
    • 1:CAS:528:DC%2BD28XlvVCnsbg%3D 16652377
    • MC Myzak E Ho RH Dashwood 2006 Dietary agents as histone deacetylase inhibitors Mol Carcinog 45 443 446 1:CAS:528:DC%2BD28XlvVCnsbg%3D 16652377
    • (2006) Mol Carcinog , vol.45 , pp. 443-446
    • Myzak, M.C.1    Ho, E.2    Dashwood, R.H.3
  • 81
    • 33746752125 scopus 로고    scopus 로고
    • A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
    • 1:CAS:528:DC%2BD28XosFGjtbg%3D 16901784
    • M Narita M Narita V Krizhanovsky, et al. 2006 A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation Cell 126 503 514 1:CAS:528:DC%2BD28XosFGjtbg%3D 16901784
    • (2006) Cell , vol.126 , pp. 503-514
    • Narita, M.1    Narita, M.2    Krizhanovsky, V.3
  • 82
    • 26844558334 scopus 로고    scopus 로고
    • Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
    • 1:CAS:528:DC%2BD2MXhtV2hurvO 16224023
    • E Nisoli C Tonello A Cardile, et al. 2005 Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS Science 310 314 317 1:CAS:528:DC%2BD2MXhtV2hurvO 16224023
    • (2005) Science , vol.310 , pp. 314-317
    • Nisoli, E.1    Tonello, C.2    Cardile, A.3
  • 83
    • 56749156405 scopus 로고    scopus 로고
    • SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
    • 1:CAS:528:DC%2BD1cXhsV2jtr%2FF 19041753
    • P Oberdoerffer S Michan M McVay, et al. 2008 SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging Cell 135 907 918 1:CAS:528:DC%2BD1cXhsV2jtr%2FF 19041753
    • (2008) Cell , vol.135 , pp. 907-918
    • Oberdoerffer, P.1    Michan, S.2    McVay, M.3
  • 84
    • 50849104569 scopus 로고    scopus 로고
    • Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
    • 18704159
    • HM O'Hagan HP Mohammad SB Baylin 2008 Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island PLoS Genet 4 e1000155 18704159
    • (2008) PLoS Genet , vol.4 , pp. 1000155
    • O'Hagan, H.M.1    Mohammad, H.P.2    Baylin, S.B.3
  • 85
    • 0035114222 scopus 로고    scopus 로고
    • Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans
    • 1:CAS:528:DC%2BD3MXhs1Sgs74%3D 11237928
    • MR Olthof PC Hollman PL Zock, et al. 2001 Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans Am J Clin Nutr 73 532 538 1:CAS:528:DC%2BD3MXhs1Sgs74%3D 11237928
    • (2001) Am J Clin Nutr , vol.73 , pp. 532-538
    • Olthof, M.R.1    Hollman, P.C.2    Zock, P.L.3
  • 86
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • 1:CAS:528:DC%2BD3sXjt1GjsLg%3D 12719720
    • M Oren 2003 Decision making by p53: life, death and cancer Cell Death Differ 10 431 442 1:CAS:528:DC%2BD3sXjt1GjsLg%3D 12719720
    • (2003) Cell Death Differ , vol.10 , pp. 431-442
    • Oren, M.1
  • 87
    • 30544445468 scopus 로고    scopus 로고
    • Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells
    • 1:CAS:528:DC%2BD28XjtV2isA%3D%3D 16170353
    • H Ota E Tokunaga K Chang, et al. 2006 Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells Oncogene 25 176 185 1:CAS:528:DC%2BD28XjtV2isA%3D%3D 16170353
    • (2006) Oncogene , vol.25 , pp. 176-185
    • Ota, H.1    Tokunaga, E.2    Chang, K.3
  • 88
    • 6344294841 scopus 로고    scopus 로고
    • Mediterranean diet and cognitive decline
    • 1:STN:280:DC%2BD2crhtlKlsQ%3D%3D 15482625
    • F Panza V Solfrizzi AM Colacicco, et al. 2004 Mediterranean diet and cognitive decline Public Health Nutr 7 959 963 1:STN:280:DC%2BD2crhtlKlsQ%3D%3D 15482625
    • (2004) Public Health Nutr , vol.7 , pp. 959-963
    • Panza, F.1    Solfrizzi, V.2    Colacicco, A.M.3
  • 89
    • 16344363621 scopus 로고    scopus 로고
    • Gene expression profiling studies of aging in cardiac and skeletal muscles
    • 1:CAS:528:DC%2BD2MXivFyqtrc%3D 15820189
    • SK Park TA Prolla 2005 Gene expression profiling studies of aging in cardiac and skeletal muscles Cardiovasc Res 66 205 212 1:CAS:528: DC%2BD2MXivFyqtrc%3D 15820189
    • (2005) Cardiovasc Res , vol.66 , pp. 205-212
    • Park, S.K.1    Prolla, T.A.2
  • 90
    • 33645768490 scopus 로고    scopus 로고
    • Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
    • 16596166
    • K Pruitt RL Zinn JE Ohm, et al. 2006 Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation PLoS Genet 2 e40 16596166
    • (2006) PLoS Genet , vol.2 , pp. 40
    • Pruitt, K.1    Zinn, R.L.2    Ohm, J.E.3
  • 91
    • 0038523843 scopus 로고    scopus 로고
    • Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: A case control study
    • 1:CAS:528:DC%2BD3sXktVSktro%3D 12730865
    • M Pufulete R Al-Ghnaniem AJ Leather, et al. 2003 Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study Gastroenterology 124 1240 1248 1:CAS:528:DC%2BD3sXktVSktro%3D 12730865
    • (2003) Gastroenterology , vol.124 , pp. 1240-1248
    • Pufulete, M.1    Al-Ghnaniem, R.2    Leather, A.J.3
  • 92
    • 16244389260 scopus 로고    scopus 로고
    • Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer
    • 1:CAS:528:DC%2BD2MXitV2jurg%3D 15726099
    • M Pufulete R Al-Ghnaniem JA Rennie, et al. 2005 Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer Br J Cancer 92 838 842 1:CAS:528: DC%2BD2MXitV2jurg%3D 15726099
    • (2005) Br J Cancer , vol.92 , pp. 838-842
    • Pufulete, M.1    Al-Ghnaniem, R.2    Rennie, J.A.3
  • 93
    • 0033805888 scopus 로고    scopus 로고
    • Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
    • 1:CAS:528:DC%2BD3cXnt1amt7k%3D 11010943
    • GC Rampersaud GP Kauwell AD Hutson, et al. 2000 Genomic DNA methylation decreases in response to moderate folate depletion in elderly women Am J Clin Nutr 72 998 1003 1:CAS:528:DC%2BD3cXnt1amt7k%3D 11010943
    • (2000) Am J Clin Nutr , vol.72 , pp. 998-1003
    • Rampersaud, G.C.1    Kauwell, G.P.2    Hutson, A.D.3
  • 94
    • 42449100009 scopus 로고    scopus 로고
    • Isoflavones promote mitochondrial biogenesis
    • 1:CAS:528:DC%2BD1cXlsVOjtrs%3D 18267976
    • KA Rasbach RG Schnellmann 2008 Isoflavones promote mitochondrial biogenesis J Pharmacol Exp Ther 325 536 543 1:CAS:528:DC%2BD1cXlsVOjtrs%3D 18267976
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 536-543
    • Rasbach, K.A.1    Schnellmann, R.G.2
  • 95
    • 0018564390 scopus 로고
    • A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: Evidence for and identification of cryptic mating-type loci
    • 1:STN:280:DyaL3c3gt1Ghsw%3D%3D 397913
    • J Rine JN Strathern JB Hicks, et al. 1979 A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci Genetics 93 877 901 1:STN:280:DyaL3c3gt1Ghsw%3D%3D 397913
    • (1979) Genetics , vol.93 , pp. 877-901
    • Rine, J.1    Strathern, J.N.2    Hicks, J.B.3
  • 96
    • 39449103319 scopus 로고    scopus 로고
    • Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells
    • 1:CAS:528:DC%2BD1cXitVKktro%3D 18084025
    • J Rodriguez L Vives M Jorda, et al. 2008 Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells Nucleic Acids Res 36 770 784 1:CAS:528:DC%2BD1cXitVKktro%3D 18084025
    • (2008) Nucleic Acids Res , vol.36 , pp. 770-784
    • Rodriguez, J.1    Vives, L.2    Jorda, M.3
  • 97
    • 8644224064 scopus 로고    scopus 로고
    • Sir2 mediates longevity in the fly through a pathway related to calorie restriction
    • 1:CAS:528:DC%2BD2cXhtVGis77E 15520384
    • B Rogina SL Helfand 2004 Sir2 mediates longevity in the fly through a pathway related to calorie restriction Proc Natl Acad Sci USA 101 15998 16003 1:CAS:528:DC%2BD2cXhtVGis77E 15520384
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15998-16003
    • Rogina, B.1    Helfand, S.L.2
  • 98
    • 0000062739 scopus 로고
    • Length of life and nutrition in the rat
    • 1:CAS:528:DyaF3sXksVeks7k%3D 14494200
    • MH Ross 1961 Length of life and nutrition in the rat J Nutr 75 197 210 1:CAS:528:DyaF3sXksVeks7k%3D 14494200
    • (1961) J Nutr , vol.75 , pp. 197-210
    • Ross, M.H.1
  • 99
    • 0036194094 scopus 로고    scopus 로고
    • Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats
    • 1:CAS:528:DC%2BD38XitFSqsbs%3D 11880556
    • MJ Rowling MH McMullen KL Schalinske 2002 Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats J Nutr 132 365 369 1:CAS:528:DC%2BD38XitFSqsbs%3D 11880556
    • (2002) J Nutr , vol.132 , pp. 365-369
    • Rowling, M.J.1    McMullen, M.H.2    Schalinske, K.L.3
  • 100
    • 0037131426 scopus 로고    scopus 로고
    • Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging
    • 1:CAS:528:DC%2BD38XnvVeisLk%3D 12154089
    • B Sarg E Koutzamani W Helliger, et al. 2002 Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging J Biol Chem 277 39195 39201 1:CAS:528:DC%2BD38XnvVeisLk%3D 12154089
    • (2002) J Biol Chem , vol.277 , pp. 39195-39201
    • Sarg, B.1    Koutzamani, E.2    Helliger, W.3
  • 101
    • 33749545356 scopus 로고    scopus 로고
    • Gluconeogenesis: Re-evaluating the FOXO1-PGC-1alpha connection
    • 1:CAS:528:DC%2BD28XhtVCiu73L 17024043
    • MM Schilling JK Oeser JN Boustead, et al. 2006 Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection Nature 443 E10 E11 1:CAS:528:DC%2BD28XhtVCiu73L 17024043
    • (2006) Nature , vol.443
    • Schilling, M.M.1    Oeser, J.K.2    Boustead, J.N.3
  • 102
    • 51649112590 scopus 로고    scopus 로고
    • Sirt1-null mice develop an autoimmune-like condition
    • 1:CAS:528:DC%2BD1cXhtFCktbbP 18687325
    • J Sequeira G Boily S Bazinet, et al. 2008 sirt1-null mice develop an autoimmune-like condition Exp Cell Res 314 3069 3074 1:CAS:528: DC%2BD1cXhtFCktbbP 18687325
    • (2008) Exp Cell Res , vol.314 , pp. 3069-3074
    • Sequeira, J.1    Boily, G.2    Bazinet, S.3
  • 103
    • 0027441579 scopus 로고
    • Diet and the suitability of the male Fischer 344 rat as a model for aging research
    • 1:STN:280:DyaK3s7hsFCiug%3D%3D 8418135
    • I Shimokawa Y Higami GB Hubbard, et al. 1993 Diet and the suitability of the male Fischer 344 rat as a model for aging research J Gerontol 48 B27 B32 1:STN:280:DyaK3s7hsFCiug%3D%3D 8418135
    • (1993) J Gerontol , vol.48
    • Shimokawa, I.1    Higami, Y.2    Hubbard, G.B.3
  • 104
    • 0031459980 scopus 로고    scopus 로고
    • Extrachromosomal rDNA circles-a cause of aging in yeast
    • 1:CAS:528:DyaK1cXjtVKitQ%3D%3D 9428525
    • DA Sinclair L Guarente 1997 Extrachromosomal rDNA circles-a cause of aging in yeast Cell 91 1033 1042 1:CAS:528:DyaK1cXjtVKitQ%3D%3D 9428525
    • (1997) Cell , vol.91 , pp. 1033-1042
    • Sinclair, D.A.1    Guarente, L.2
  • 105
    • 0036558155 scopus 로고    scopus 로고
    • Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer
    • 1:CAS:528:DC%2BD38XjtlGrsLw%3D 11980632
    • SM Sirchia M Ren R Pili, et al. 2002 Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer Cancer Res 62 2455 2461 1:CAS:528:DC%2BD38XjtlGrsLw%3D 11980632
    • (2002) Cancer Res , vol.62 , pp. 2455-2461
    • Sirchia, S.M.1    Ren, M.2    Pili, R.3
  • 106
    • 0030053650 scopus 로고    scopus 로고
    • Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae
    • 1:CAS:528:DyaK28Xhtlems74%3D 8598049
    • T Smeal J Claus B Kennedy, et al. 1996 Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae Cell 84 633 642 1:CAS:528:DyaK28Xhtlems74%3D 8598049
    • (1996) Cell , vol.84 , pp. 633-642
    • Smeal, T.1    Claus, J.2    Kennedy, B.3
  • 107
    • 0036288659 scopus 로고    scopus 로고
    • Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle
    • 1:CAS:528:DC%2BD38XlsVCrsb8%3D 12067840
    • R Sreekumar J Unnikrishnan A Fu, et al. 2002 Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle Am J Physiol Endocrinol Metab 283 E38 E43 1:CAS:528:DC%2BD38XlsVCrsb8%3D 12067840
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Sreekumar, R.1    Unnikrishnan, J.2    Fu, A.3
  • 108
    • 19844371353 scopus 로고    scopus 로고
    • Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model
    • 1:CAS:528:DC%2BD2MXjsFOmsrk%3D 15695236
    • JM Stempak KJ Sohn EP Chiang, et al. 2005 Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model Carcinogenesis 26 981 990 1:CAS:528:DC%2BD2MXjsFOmsrk%3D 15695236
    • (2005) Carcinogenesis , vol.26 , pp. 981-990
    • Stempak, J.M.1    Sohn, K.J.2    Chiang, E.P.3
  • 109
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • 1:CAS:528:DC%2BD3MXitVyqtbg%3D 11242085
    • HA Tissenbaum L Guarente 2001 Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 227 230 1:CAS:528: DC%2BD3MXitVyqtbg%3D 11242085
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 110
    • 18044368276 scopus 로고    scopus 로고
    • Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study
    • 15820966
    • A Trichopoulou P Orfanos T Norat, et al. 2005 Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study BMJ 330 991 15820966
    • (2005) BMJ , vol.330 , pp. 991
    • Trichopoulou, A.1    Orfanos, P.2    Norat, T.3
  • 111
    • 4944245398 scopus 로고    scopus 로고
    • Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
    • 1:CAS:528:DC%2BD2cXptVKqtrw%3D 15469825
    • A Vaquero M Scher D Lee, et al. 2004 Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin Mol Cell 16 93 105 1:CAS:528:DC%2BD2cXptVKqtrw%3D 15469825
    • (2004) Mol Cell , vol.16 , pp. 93-105
    • Vaquero, A.1    Scher, M.2    Lee, D.3
  • 112
    • 36248954501 scopus 로고    scopus 로고
    • SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
    • 1:CAS:528:DC%2BD2sXhtlajs7%2FM 18004385
    • A Vaquero M Scher H Erdjument-Bromage, et al. 2007 SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation Nature 450 440 444 1:CAS:528:DC%2BD2sXhtlajs7%2FM 18004385
    • (2007) Nature , vol.450 , pp. 440-444
    • Vaquero, A.1    Scher, M.2    Erdjument-Bromage, H.3
  • 113
    • 0033977890 scopus 로고    scopus 로고
    • The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
    • 1:CAS:528:DC%2BD3cXhtF2ntb8%3D 10669761
    • RB Vega JM Huss DP Kelly 2000 The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes Mol Cell Biol 20 1868 1876 1:CAS:528:DC%2BD3cXhtF2ntb8%3D 10669761
    • (2000) Mol Cell Biol , vol.20 , pp. 1868-1876
    • Vega, R.B.1    Huss, J.M.2    Kelly, D.P.3
  • 114
    • 0030759780 scopus 로고    scopus 로고
    • The heterochromatin loss model of aging
    • 1:STN:280:DyaK2svmtFSktA%3D%3D 9315443
    • B Villeponteau 1997 The heterochromatin loss model of aging Exp Gerontol 32 383 394 1:STN:280:DyaK2svmtFSktA%3D%3D 9315443
    • (1997) Exp Gerontol , vol.32 , pp. 383-394
    • Villeponteau, B.1
  • 115
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans
    • 1:CAS:528:DC%2BD2cXhtFGitrfE 15333514
    • T Walle F Hsieh MH DeLegge, et al. 2004 High absorption but very low bioavailability of oral resveratrol in humans Drug Metab Dispos 32 1377 1382 1:CAS:528:DC%2BD2cXhtFGitrfE 15333514
    • (2004) Drug Metab Dispos , vol.32 , pp. 1377-1382
    • Walle, T.1    Hsieh, F.2    Delegge, M.H.3
  • 116
    • 0021972234 scopus 로고
    • Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver
    • 1:CAS:528:DyaL2MXhtlSrsrg%3D 3968590
    • JC Wallwork JA Duerre 1985 Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver J Nutr 115 252 262 1:CAS:528:DyaL2MXhtlSrsrg%3D 3968590
    • (1985) J Nutr , vol.115 , pp. 252-262
    • Wallwork, J.C.1    Duerre, J.A.2
  • 117
    • 33751101893 scopus 로고    scopus 로고
    • Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation
    • 1:CAS:528:DC%2BD28XhtFGqtLbO 17056795
    • GR Wasson AP McGlynn H McNulty, et al. 2006 Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation J Nutr 136 2748 2753 1:CAS:528:DC%2BD28XhtFGqtLbO 17056795
    • (2006) J Nutr , vol.136 , pp. 2748-2753
    • Wasson, G.R.1    McGlynn, A.P.2    McNulty, H.3
  • 118
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
    • 1:CAS:528:DC%2BD3sXlslGmsrw%3D 12861015
    • RA Waterland RL Jirtle 2003 Transposable elements: targets for early nutritional effects on epigenetic gene regulation Mol Cell Biol 23 5293 5300 1:CAS:528:DC%2BD3sXlslGmsrw%3D 12861015
    • (2003) Mol Cell Biol , vol.23 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 119
    • 35248840160 scopus 로고    scopus 로고
    • Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female
    • DOI 10.1096/fj.07-8229com
    • RA Waterland M Travisano KG Tahiliani 2007 Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female Faseb J 21 3380 3385 1:CAS:528:DC%2BD2sXhtFKntbbN 17551099 (Pubitemid 47565556)
    • (2007) FASEB Journal , vol.21 , Issue.12 , pp. 3380-3385
    • Waterland, R.A.1    Travisano, M.2    Tahiliani, K.G.3
  • 120
    • 0020044308 scopus 로고
    • Dietary restriction in mice beginning at 1 year of age: Effect on life-span and spontaneous cancer incidence
    • 1:STN:280:DyaL387lt1OlsA%3D%3D 7063854
    • R Weindruch RL Walford 1982 Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence Science 215 1415 1418 1:STN:280:DyaL387lt1OlsA%3D%3D 7063854
    • (1982) Science , vol.215 , pp. 1415-1418
    • Weindruch, R.1    Walford, R.L.2
  • 121
    • 0022517746 scopus 로고
    • The retardation of aging in mice by dietary restriction: Longevity, cancer, immunity and lifetime energy intake
    • 1:STN:280:DyaL287ntVygsQ%3D%3D 3958810
    • R Weindruch RL Walford S Fligiel, et al. 1986 The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake J Nutr 116 641 654 1:STN:280:DyaL287ntVygsQ%3D%3D 3958810
    • (1986) J Nutr , vol.116 , pp. 641-654
    • Weindruch, R.1    Walford, R.L.2    Fligiel, S.3
  • 122
    • 33746633037 scopus 로고    scopus 로고
    • Caloric restriction and human longevity: What can we learn from the Okinawans?
    • 16810568
    • DC Willcox BJ Willcox H Todoriki, et al. 2006 Caloric restriction and human longevity: what can we learn from the Okinawans? Biogerontology 7 173 177 16810568
    • (2006) Biogerontology , vol.7 , pp. 173-177
    • Willcox, D.C.1    Willcox, B.J.2    Todoriki, H.3
  • 123
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • 1:CAS:528:DyaL3sXktVenurk%3D 6844925
    • VL Wilson PA Jones 1983 DNA methylation decreases in aging but not in immortal cells Science 220 1055 1057 1:CAS:528:DyaL3sXktVenurk%3D 6844925
    • (1983) Science , vol.220 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 124
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • 1:CAS:528:DyaK1MXks1Kktrs%3D 10412986
    • Z Wu P Puigserver U Andersson, et al. 1999 Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1 Cell 98 115 124 1:CAS:528:DyaK1MXks1Kktrs%3D 10412986
    • (1999) Cell , vol.98 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3
  • 125
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • 14973332
    • AS Yang MR Estecio K Doshi, et al. 2004 A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements Nucleic Acids Res 32 e38 14973332
    • (2004) Nucleic Acids Res , vol.32 , pp. 38
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3
  • 126
    • 0020059410 scopus 로고
    • Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: Longevity, growth, lean body mass and disease
    • 1:STN:280:DyaL387itFSjtA%3D%3D 7056998
    • BP Yu EJ Masoro I Murata, et al. 1982 Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: longevity, growth, lean body mass and disease J Gerontol 37 130 141 1:STN:280:DyaL387itFSjtA%3D%3D 7056998
    • (1982) J Gerontol , vol.37 , pp. 130-141
    • Yu, B.P.1    Masoro, E.J.2    Murata, I.3
  • 127
    • 0033817976 scopus 로고    scopus 로고
    • Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle
    • 1:CAS:528:DC%2BD3cXms1Cmur0%3D 10973932
    • TA Zainal TD Oberley DB Allison, et al. 2000 Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle Faseb J 14 1825 1836 1:CAS:528:DC%2BD3cXms1Cmur0%3D 10973932
    • (2000) Faseb J , vol.14 , pp. 1825-1836
    • Zainal, T.A.1    Oberley, T.D.2    Allison, D.B.3


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