Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: A model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration

Neuron

Volumn 42, Issue 6, 2004, Pages 947-959

  Alarcón, Juan M ^a   Malleret, Gaël ^a   Touzani, Khalid ^a   Vronskaya, Svetlana ^a   Ishii, Shunsuke ^c   Kandel, Eric R ^a,b   Barco, Angel ^a  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c RIKEN TSUKUBA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HISTONE ACETYLTRANSFERASE;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVITY; FEAR; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; MEMORY; MEMORY DISORDER; MOLECULAR GENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RUBINSTEIN SYNDROME;

ACETYLATION; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; CHROMATIN; CONDITIONING (PSYCHOLOGY); CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; DYNORPHINS; ELECTROPHYSIOLOGY; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIALS; FEAR; FEMALE; GENE EXPRESSION; HETEROZYGOTE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; NEURAL INHIBITION; NEURONS; NUCLEAR PROTEINS; PHOSPHODIESTERASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-FOS; PSYCHOMOTOR PERFORMANCE; REACTION TIME; RECOGNITION (PSYCHOLOGY); ROLIPRAM; RUBINSTEIN-TAYBI SYNDROME; SYNAPTOPHYSIN; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 2942705826     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2004.05.021     Document Type: Article

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