Xenotransplantation: Immunological hurdles and progress toward tolerance

Immunological Reviews

Volumn 258, Issue 1, 2014, Pages 241-258

  Griesemer, Adam ^a   Yamada, Kazuhiko ^b   Sykes, Megan ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Genetically modified swine; Mixed chimerism; NK cells; Thymus transplant; Tolerance; Xenotransplantation

Indexed keywords

ADAPTIVE IMMUNITY; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY RESPONSE; B LYMPHOCYTE; CHIMERA; CYTOTOXICITY; DISEASE TRANSMISSION; DNA MODIFICATION; ENDOGENOUS RETROVIRUS; GENETIC MANIPULATION; GRAFT REJECTION; HEART GRAFT; HLA SYSTEM; HUMAN; IMMUNOGLOBULIN PRODUCING CELL; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; KIDNEY GRAFT; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; RHESUS MONKEY; RISK REDUCTION; T LYMPHOCYTE; THYMUS GRAFT; THYMUS TRANSPLANTATION; TRANSGENE; TRANSPLANTATION TOLERANCE; XENOGRAFT; XENOTRANSPLANTATION; ANIMAL; CELLULAR IMMUNITY; GRAFT SURVIVAL; HISTOCOMPATIBILITY; HUMORAL IMMUNITY; IMMUNOLOGY; ORGAN TRANSPLANTATION; THYMUS; TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; ORGAN TRANSPLANTATION; THYMUS GLAND; TRANSPLANTATION CHIMERA; TRANSPLANTATION TOLERANCE; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME;

EID: 84893565575     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12152     Document Type: Review

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