-
1
-
-
39749109478
-
Triggers, targets and treatments for thrombosis
-
Mackman N. Triggers, targets and treatments for thrombosis. Nature 2008; 451:914-918.
-
(2008)
Nature
, vol.451
, pp. 914-918
-
-
MacKman, N.1
-
2
-
-
50449098285
-
Mechanisms of thrombus formation
-
Furie B, Furie BC. Mechanisms of thrombus formation. N Engl J Med 2008; 359:938-949.
-
(2008)
N Engl J Med
, vol.359
, pp. 938-949
-
-
Furie, B.1
Furie, B.C.2
-
3
-
-
32244438720
-
Tissue factor pathway inhibitor: Structure, biology and involvement in disease
-
DOI 10.1002/path.1871
-
Lwaleed BA, Bass PS. Tissue factor pathway inhibitor: structure, biology and involvement in disease. J Pathol 2006; 208:327-339. (Pubitemid 43210519)
-
(2006)
Journal of Pathology
, vol.208
, Issue.3
, pp. 327-339
-
-
Lwaleed, B.A.1
Bass, P.S.2
-
4
-
-
77956547096
-
The Kunitz-3 domain of TFPI-alpha is required for protein S-dependent enhancement of factor Xa inhibition
-
Ndonwi M, Tuley EA, Broze GJ Jr. The Kunitz-3 domain of TFPI-alpha is required for protein S-dependent enhancement of factor Xa inhibition. Blood 2010; 116:1344-1351.
-
(2010)
Blood
, vol.116
, pp. 1344-1351
-
-
Ndonwi, M.1
Tuley, E.A.2
Broze Jr., G.J.3
-
5
-
-
34250787144
-
Serpins in thrombosis, hemostasis and fibrinolysis
-
DOI 10.1111/j.1538-7836.2006.02283.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
-
Rau JC, Beaulieu LM, Huntington JA, Church FC. Serpins in thrombosis, hemostasis and fibrinolysis. J Thromb Haemost 2007; 5 (Suppl. 1):102-115. (Pubitemid 46958823)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.SUPPL. 1
, pp. 102-115
-
-
Rau, J.C.1
Beaulieu, L.M.2
Huntington, J.A.3
Church, F.C.4
-
6
-
-
20444427991
-
The anticoagulant protein C pathway
-
DOI 10.1016/j.febslet.2005.03.001, PII S0014579305003066
-
Dahlback B, Villoutreix BO. The anticoagulant protein C pathway. FEBS Lett 2005; 579:3310-3316. (Pubitemid 40804679)
-
(2005)
FEBS Letters
, vol.579
, Issue.15
, pp. 3310-3316
-
-
Dahlback, B.1
Villoutreix, B.O.2
-
7
-
-
0035869411
-
Endothelial cell protein C receptor plays an important role in protein C activation in vivo
-
DOI 10.1182/blood.V97.6.1685
-
Taylor FB Jr, Peer GT, Lockhart MS, et al. Endothelial cell protein C receptor plays an important role in protein C activation in vivo. Blood 2001; 97:1685-1688. (Pubitemid 32217234)
-
(2001)
Blood
, vol.97
, Issue.6
, pp. 1685-1688
-
-
Taylor Jr., F.B.1
Peer, G.T.2
Lockhart, M.S.3
Ferrell, G.4
Esmon, C.T.5
-
8
-
-
77949515745
-
The protein C pathway in tissue inflammation and injury: Pathogenic role and therapeutic implications
-
Danese S, Vetrano S, Zhang L, et al. The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications. Blood 2010; 115:1121-1130.
-
(2010)
Blood
, vol.115
, pp. 1121-1130
-
-
Danese, S.1
Vetrano, S.2
Zhang, L.3
-
10
-
-
70350512348
-
Coagulation and innate immune responses: Can we view them separately?
-
Delvaeye M, Conway EM. Coagulation and innate immune responses: can we view them separately? Blood 2009; 114:2367-2374.
-
(2009)
Blood
, vol.114
, pp. 2367-2374
-
-
Delvaeye, M.1
Conway, E.M.2
-
11
-
-
43449093705
-
Evidence for nontraditional activation of complement factor C3 during murine liver regeneration
-
Clark A, Weymann A, Hartman E, et al. Evidence for nontraditional activation of complement factor C3 during murine liver regeneration. Mol Immunol 2008; 45:3125-3132.
-
(2008)
Mol Immunol
, vol.45
, pp. 3125-3132
-
-
Clark, A.1
Weymann, A.2
Hartman, E.3
-
12
-
-
33744987414
-
Generation of C5a in the absence of C3: A new complement activation pathway
-
DOI 10.1038/nm1419, PII N1419
-
Huber-Lang M, Sarma JV, Zetoune FS, et al. Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med 2006; 12:682-687. (Pubitemid 43865238)
-
(2006)
Nature Medicine
, vol.12
, Issue.6
, pp. 682-687
-
-
Huber-Lang, M.1
Sarma, J.V.2
Zetoune, F.S.3
Rittirsch, D.4
Neff, T.A.5
McGuire, S.R.6
Lambris, J.D.7
Warner, R.L.8
Flierl, M.A.9
Hoesel, L.M.10
Gebhard, F.11
Younger, J.G.12
Drouin, S.M.13
Wetsel, R.A.14
Ward, P.A.15
-
13
-
-
33749118495
-
A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways
-
Ritis K, Doumas M, Mastellos D, et al. A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. J Immunol 2006; 177:4794-4802. (Pubitemid 44469814)
-
(2006)
Journal of Immunology
, vol.177
, Issue.7
, pp. 4794-4802
-
-
Ritis, K.1
Doumas, M.2
Mastellos, D.3
Micheli, A.4
Giaglis, S.5
Magotti, P.6
Rafail, S.7
Kartalis, G.8
Sideras, P.9
Lambris, J.D.10
-
14
-
-
71149116751
-
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo
-
Muller F, Mutch NJ, Schenk WA, et al. Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell 2009; 139:1143-1156.
-
(2009)
Cell
, vol.139
, pp. 1143-1156
-
-
Muller, F.1
Mutch, N.J.2
Schenk, W.A.3
-
15
-
-
0025963529
-
Regulation of thrombomodulin by tumor necrosis factor-alpha: Comparison of transcriptional and posttranscriptional mechanisms
-
Lentz SR, Tsiang M, Sadler JE. Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms. Blood 1991; 77:542-550.
-
(1991)
Blood
, vol.77
, pp. 542-550
-
-
Lentz, S.R.1
Tsiang, M.2
Sadler, J.E.3
-
16
-
-
0346155802
-
Thrombomodulin RNA Is Destabilized Through Its 3′-Untranslated Element in Cells Exposed to IFN-γ
-
DOI 10.1089/107999003772084833
-
Navarro A, Frevel M, Gamero AM, et al. Thrombomodulin RNA is destabilized through its 30-untranslated element in cells exposed to IFN-gamma. J Interferon Cytokine Res 2003; 23:723-728. (Pubitemid 38041443)
-
(2003)
Journal of Interferon and Cytokine Research
, vol.23
, Issue.12
, pp. 723-728
-
-
Navarro, A.1
Frevel, M.2
Gamero, A.M.3
Williams, B.R.G.4
Feldman, G.5
Larner, A.C.6
-
17
-
-
0025241217
-
Plasma thrombomodulin in health and diseases
-
Takano S, Kimura S, Ohdama S, Aoki N. Plasma thrombomodulin in health and diseases. Blood 1990; 76:2024-2029.
-
(1990)
Blood
, vol.76
, pp. 2024-2029
-
-
Takano, S.1
Kimura, S.2
Ohdama, S.3
Aoki, N.4
-
18
-
-
34247853512
-
Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3
-
DOI 10.1111/j.1538-7836.2007.02480.x
-
Villegas-Mendez A, Montes R, Ambrose LR, et al. Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3. J Thromb Haemost 2007; 5:980-988. (Pubitemid 46691727)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.5
, pp. 980-988
-
-
Villegas-Mendez, A.1
Montes, R.2
Ambrose, L.R.3
Warrens, A.N.4
Laffan, M.5
Lane, D.A.6
-
19
-
-
67651036210
-
Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
-
Menschikowski M, Hagelgans A, Eisenhofer G, Siegert G. Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways. Exp Cell Res 2009; 315:2673-2682.
-
(2009)
Exp Cell Res
, vol.315
, pp. 2673-2682
-
-
Menschikowski, M.1
Hagelgans, A.2
Eisenhofer, G.3
Siegert, G.4
-
20
-
-
77955410626
-
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
-
Massberg S, Grahl L, von Bruehl ML, et al. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat Med 2010; 16:887-896.
-
(2010)
Nat Med
, vol.16
, pp. 887-896
-
-
Massberg, S.1
Grahl, L.2
Von Bruehl, M.L.3
-
21
-
-
33745848867
-
Endothelium and allotransplantation
-
DOI 10.1097/01.tp.0000231345.23918.bd, PII 0000789020060715100004
-
Aird WC. Endothelium and allotransplantation. Transplantation 2006; 82 (1 Suppl.):S6-S8. (Pubitemid 44035977)
-
(2006)
Transplantation
, vol.82
, Issue.SUPPL. 1
-
-
Aird, W.C.1
-
22
-
-
77954048044
-
Thrombotic microangiopathy after kidney transplantation
-
Noris M, Remuzzi G. Thrombotic microangiopathy after kidney transplantation. Am J Transplant 2010; 10:1517-1523.
-
(2010)
Am J Transplant
, vol.10
, pp. 1517-1523
-
-
Noris, M.1
Remuzzi, G.2
-
23
-
-
0034653591
-
Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: Protective effects of sCR1 and heparin
-
Bennet W, Sundberg B, Lundgren T, et al. Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomolgus monkeys: protective effects of sCR1 and heparin. Transplantation 2000; 69:711-719. (Pubitemid 30174086)
-
(2000)
Transplantation
, vol.69
, Issue.5
, pp. 711-719
-
-
Bennet, W.1
Sundberg, B.2
Lundgren, T.3
Tibell, A.4
Groth, C.-G.5
Richards, A.6
White, D.J.7
Elgue, G.8
Larsson, R.9
Nilsson, B.10
Korsgren, O.11
-
24
-
-
20044371024
-
Tissue factor produced by the endocrine cells of the islets of langerhans is associated with a negative outcome of clinical islet transplantation
-
DOI 10.2337/diabetes.54.6.1755
-
Johansson H, Lukinius A, Moberg L, et al. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation. Diabetes 2005; 54:1755-1762. (Pubitemid 40770765)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1755-1762
-
-
Johansson, H.1
Lukinius, A.2
Moberg, L.3
Lundgren, T.4
Berne, C.5
Foss, A.6
Felldin, M.7
Kallen, R.8
Salmela, K.9
Tibell, A.10
Tufveson, G.11
Ekdahl, K.N.12
Elgue, G.13
Korsgren, O.14
Nilsson, B.15
-
25
-
-
33846590924
-
Reactivity of human natural antibodies to endothelial cells from Galα(1,3)Gal-deficient pigs
-
DOI 10.1097/01.tp.0000250478.00567.e5, PII 0000789020070127000010
-
Baumann BC, Stussi G, Huggel K, et al. Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs. Transplantation 2007; 83:193-201. (Pubitemid 46185210)
-
(2007)
Transplantation
, vol.83
, Issue.2
, pp. 193-201
-
-
Baumann, B.C.1
Stussi, G.2
Huggel, K.3
Rieben, R.4
Seebach, J.D.5
-
26
-
-
77956469984
-
Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by antinonGal IgG binding to porcine aortic endothelial cells
-
Lin CC, Ezzelarab M, Hara H, et al. Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by antinonGal IgG binding to porcine aortic endothelial cells. J Thromb Haemost 2010; 8:2001-2010.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 2001-2010
-
-
Lin, C.C.1
Ezzelarab, M.2
Hara, H.3
-
27
-
-
47249084343
-
Advances in understanding pathogenic mechanisms of thrombophilic disorders
-
Dahlback B. Advances in understanding pathogenic mechanisms of thrombophilic disorders. Blood 2008; 112:19-27.
-
(2008)
Blood
, vol.112
, pp. 19-27
-
-
Dahlback, B.1
-
28
-
-
70449107044
-
Extracellular histones are major mediators of death in sepsis
-
Xu J, Zhang X, Pelayo R, et al. Extracellular histones are major mediators of death in sepsis. Nat Med 2009; 15:1318-1321.
-
(2009)
Nat Med
, vol.15
, pp. 1318-1321
-
-
Xu, J.1
Zhang, X.2
Pelayo, R.3
-
29
-
-
0030802799
-
Xenogeneic endothelial cells activate human prothrombin
-
DOI 10.1097/00007890-199709270-00017
-
Siegel JB, Grey ST, Lesnikoski BA, et al. Xenogeneic endothelial cells activate human prothrombin. Transplantation 1997; 64:888-896. (Pubitemid 27422273)
-
(1997)
Transplantation
, vol.64
, Issue.6
, pp. 888-896
-
-
Siegel, J.B.1
Grey, S.T.2
Lesnikoski, B.-A.3
Kopp, C.W.4
Soares, M.5
Bach, F.H.6
Robson, S.C.7
-
30
-
-
0030910713
-
The evaluation of thrombomodulin activity in porcine to human xenotransplantation
-
DOI 10.1016/S0041-1345(96)00192-3, PII S0041134596001923
-
Lawson JH, Daniels LJ, Platt JL. The evaluation of thrombomodulin activity in porcine to human xenotransplantation. Transplant Proc 1997; 29:884-885. (Pubitemid 27126004)
-
(1997)
Transplantation Proceedings
, vol.29
, Issue.1-2
, pp. 884-885
-
-
Lawson, J.H.1
Daniels, L.J.2
Platt, J.L.3
-
31
-
-
44449173082
-
Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI
-
DOI 10.1111/j.1600-6143.2008.02210.x
-
Roussel JC, Moran CJ, Salvaris EJ, et al. Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI. Am J Transplant 2008; 8:1101-1112. (Pubitemid 351766700)
-
(2008)
American Journal of Transplantation
, vol.8
, Issue.6
, pp. 1101-1112
-
-
Roussel, J.C.1
Moran, C.J.2
Salvaris, E.J.3
Nandurkar, H.H.4
D'Apice, A.J.F.5
Cowan, P.J.6
-
32
-
-
76349087621
-
Potential value of human thrombomodulin and DAF expression for coagulation control in pig-to-human xenotransplantation
-
Miwa Y, Yamamoto K, Onishi A, et al. Potential value of human thrombomodulin and DAF expression for coagulation control in pig-to-human xenotransplantation. Xenotransplantation 2010; 17:26-37.
-
(2010)
Xenotransplantation
, vol.17
, pp. 26-37
-
-
Miwa, Y.1
Yamamoto, K.2
Onishi, A.3
-
33
-
-
12144279878
-
O-linked glycosylation and functional incompatibility of porcine von Willebrand factor for human platelet GPIb receptors
-
DOI 10.1111/j.1399-3089.2004.00187.x
-
Schulte Am Esch J, 2nd, Robson SC, Knoefel WT, et al. O-linked glycosylation and functional incompatibility of porcine vonWillebrand factor for human platelet GPIb receptors. Xenotransplantation 2005; 12:30-37. (Pubitemid 40105146)
-
(2005)
Xenotransplantation
, vol.12
, Issue.1
, pp. 30-37
-
-
Schulte Am Esch II, J.1
Robson, S.C.2
Knoefel, W.T.3
Hosch, S.B.4
Rogiers, X.5
-
34
-
-
0030897023
-
Effect of porcine endothelial tissue factor pathway inhibitor on human coagulation factors
-
DOI 10.1097/00007890-199703150-00023
-
Kopp CW, Siegel JB, Hancock WW, et al. Effect of porcine endothelial tissue factor pathway inhibitor on human coagulation factors. Transplantation 1997; 63:749-758. (Pubitemid 27132211)
-
(1997)
Transplantation
, vol.63
, Issue.5
, pp. 749-758
-
-
Kopp, C.W.1
Siegel, J.B.2
Hancock, W.W.3
Anrather, J.4
Winkler, H.5
Geczy, C.L.6
Kaczmarek, E.7
Bach, F.H.8
Robson, S.C.9
-
35
-
-
0031909830
-
Regulation of monocyte tissue factor activity by allogeneic and xenogeneic endothelial cells
-
Kopp CW, Robson SC, Siegel JB, et al. Regulation of monocyte tissue factor activity by allogeneic and xenogeneic endothelial cells. Thromb Haemost 1998; 79:529-538. (Pubitemid 28120785)
-
(1998)
Thrombosis and Haemostasis
, vol.79
, Issue.3
, pp. 529-538
-
-
Kopp, C.W.1
Robson, S.C.2
Siegel, J.B.3
Anrather, J.4
Winkler, H.5
Grey, S.6
Kaczmarek, E.7
Bach, F.H.8
Geczy, C.L.9
-
36
-
-
47349107350
-
Recombinant pig TFPI efficiently regulates human tissue factor pathways
-
DOI 10.1111/j.1399-3089.2008.00476.x
-
Lee KF, Salvaris EJ, Roussel JC, et al. Recombinant pig TFPI efficiently regulates human tissue factor pathways. Xenotransplantation 2008; 15:191-197. (Pubitemid 352000255)
-
(2008)
Xenotransplantation
, vol.15
, Issue.3
, pp. 191-197
-
-
Lee, K.F.E.1
Salvaris, E.J.2
Roussel, J.-C.3
Robson, S.C.4
D'Apice, A.J.F.5
Cowan, P.J.6
-
37
-
-
53449098952
-
Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells
-
Lin CC, Chen D, McVey JH, et al. Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells. Transplantation 2008; 86:702-709.
-
(2008)
Transplantation
, vol.86
, pp. 702-709
-
-
Lin, C.C.1
Chen, D.2
McVey, J.H.3
-
38
-
-
2142820093
-
Endothelial Induction of fgl2 Contributes to Thrombosis during Acute Vascular Xenograft Rejection
-
Ghanekar A, Mendicino M, Liu H, et al. Endothelial induction of fgl2 contributes to thrombosis during acute vascular xenograft rejection. J Immunol 2004; 172:5693-5701. (Pubitemid 38542073)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5693-5701
-
-
Ghanekar, A.1
Mendicino, M.2
Liu, H.3
He, W.4
Liu, M.5
Zhong, R.6
Phillips, M.J.7
Levy, G.A.8
Grant, D.R.9
-
39
-
-
77957165258
-
Reference values for thromboelastometry (ROTEM(R)) in cynomolgus monkeys (Macaca fascicularis)
-
Spiezia L, Bertini D, Boldrin M, et al. Reference values for thromboelastometry (ROTEM(R)) in cynomolgus monkeys (Macaca fascicularis). Thromb Res 2010; 126:e294-e297.
-
(2010)
Thromb Res
, vol.126
-
-
Spiezia, L.1
Bertini, D.2
Boldrin, M.3
-
40
-
-
67349190309
-
Coagulation dysregulation as a barrier to xenotransplantation in the primate
-
Lin CC, Cooper DK, Dorling A. Coagulation dysregulation as a barrier to xenotransplantation in the primate. Transpl Immunol 2009; 21:75-80.
-
(2009)
Transpl Immunol
, vol.21
, pp. 75-80
-
-
Lin, C.C.1
Cooper, D.K.2
Dorling, A.3
-
41
-
-
62849111658
-
Complement activation and coagulation in xenotransplantation
-
Cowan PJ, d'Apice AJ. Complement activation and coagulation in xenotransplantation. Immunol Cell Biol 2009; 87:203-208.
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 203-208
-
-
Cowan, P.J.1
D'Apice, A.J.2
-
42
-
-
70349655434
-
Current status of xenotransplantation and prospects for clinical application
-
Pierson RN 3rd, Dorling A, Ayares D, et al. Current status of xenotransplantation and prospects for clinical application. Xenotransplantation 2009; 16:263-280.
-
(2009)
Xenotransplantation
, vol.16
, pp. 263-280
-
-
Pierson III, R.N.1
Dorling, A.2
Ayares, D.3
-
43
-
-
77949426568
-
Overcoming the barriers to xenotransplantation: Prospects for the future
-
Ekser B, Cooper DK. Overcoming the barriers to xenotransplantation: prospects for the future. Expert Rev Clin Immunol 2010; 6:219-230.
-
(2010)
Expert Rev Clin Immunol
, vol.6
, pp. 219-230
-
-
Ekser, B.1
Cooper, D.K.2
-
45
-
-
65549162661
-
The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients
-
Ezzelarab M, Garcia B, Azimzadeh A, et al. The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients. Transplantation 2009; 87:805-812.
-
(2009)
Transplantation
, vol.87
, pp. 805-812
-
-
Ezzelarab, M.1
Garcia, B.2
Azimzadeh, A.3
-
46
-
-
77954079584
-
Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantation
-
Lin CC, Ezzelarab M, Shapiro R, et al. Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantation. Am J Transplant 2010; 10:1556-1568.
-
(2010)
Am J Transplant
, vol.10
, pp. 1556-1568
-
-
Lin, C.C.1
Ezzelarab, M.2
Shapiro, R.3
-
47
-
-
72449190098
-
Results of gal-knockout porcine thymokidney xenografts
-
Griesemer AD, Hirakata A, Shimizu A, et al. Results of gal-knockout porcine thymokidney xenografts. Am J Transplant 2009; 9:2669-2678.
-
(2009)
Am J Transplant
, vol.9
, pp. 2669-2678
-
-
Griesemer, A.D.1
Hirakata, A.2
Shimizu, A.3
-
48
-
-
44849144688
-
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from α1,3-galactosyltransferase gene-knockout pigs in baboons
-
DOI 10.2353/ajpath.2008.070672
-
Shimizu A, Hisashi Y, Kuwaki K, et al. Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol 2008; 172:1471-1481. (Pubitemid 351793341)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.6
, pp. 1471-1481
-
-
Shimizu, A.1
Hisashi, Y.2
Kuwaki, K.3
Tseng, Y.-L.4
Dor, F.J.M.F.5
Houser, S.L.6
Robson, S.C.7
Schuurman, H.-J.8
Cooper, D.K.C.9
Sachs, D.H.10
Yamada, K.11
Colvin, R.B.12
-
49
-
-
77953516571
-
First experience with heterotopic thoracic pig-to-baboon cardiac xenotransplantation
-
Bauer A, Postrach J, Thormann M, et al. First experience with heterotopic thoracic pig-to-baboon cardiac xenotransplantation. Xenotransplantation 2010; 17:243-249.
-
(2010)
Xenotransplantation
, vol.17
, pp. 243-249
-
-
Bauer, A.1
Postrach, J.2
Thormann, M.3
-
50
-
-
65249148546
-
Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation
-
Knosalla C, Yazawa K, Behdad A, et al. Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation. Am J Transplant 2009; 9:1006-1016.
-
(2009)
Am J Transplant
, vol.9
, pp. 1006-1016
-
-
Knosalla, C.1
Yazawa, K.2
Behdad, A.3
-
51
-
-
75149191343
-
Impact of thrombocytopenia on survival of baboons with genetically modified pig liver transplants: Clinical relevance
-
Ekser B, Long C, Echeverri GJ, et al. Impact of thrombocytopenia on survival of baboons with genetically modified pig liver transplants: clinical relevance. Am J Transplant 2010; 10:273-285.
-
(2010)
Am J Transplant
, vol.10
, pp. 273-285
-
-
Ekser, B.1
Long, C.2
Echeverri, G.J.3
-
52
-
-
78349272828
-
The fate of human platelets perfused through the pig liver: Implications for xenotransplantation
-
Burlak C, Paris LL, Chihara RK, et al. The fate of human platelets perfused through the pig liver: implications for xenotransplantation. Xenotransplantation 2010; 17:350-361.
-
(2010)
Xenotransplantation
, vol.17
, pp. 350-361
-
-
Burlak, C.1
Paris, L.L.2
Chihara, R.K.3
-
53
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
DOI 10.1056/NEJM200103083441001
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709. (Pubitemid 32204987)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.-L.2
Laterre, P.-F.3
LaRosa, S.P.4
Dhainaut, J.-F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher, C.J.11
-
54
-
-
38349058657
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
-
Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008; 34:17-60.
-
(2008)
Intensive Care Med
, vol.34
, pp. 17-60
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
-
55
-
-
21244438366
-
Tissue factor pathway inhibitor and anitithrombin trial results
-
DOI 10.1016/j.ccc.2005.02.002, PII S0749070405000266
-
LaRosa SP, Opal SM. Tissue factor pathway inhibitor and antithrombin trial results. Crit Care Clin 2005; 21:433-448. (Pubitemid 40898153)
-
(2005)
Critical Care Clinics
, vol.21
, Issue.3 SPEC. ISS.
, pp. 433-448
-
-
LaRosa, S.P.1
Opal, S.M.2
-
56
-
-
40549109937
-
Effects of pharmacological intervention on coagulopathy and organ function in xenoperfused kidneys
-
DOI 10.1111/j.1399-3089.2008.00443.x
-
Ramackers W, Friedrich L, Tiede A, et al. Effects of pharmacological intervention on coagulopathy and organ function in xenoperfused kidneys. Xenotransplantation 2008; 15:46-55. (Pubitemid 351360241)
-
(2008)
Xenotransplantation
, vol.15
, Issue.1
, pp. 46-55
-
-
Ramackers, W.1
Friedrich, L.2
Tiede, A.3
Bergmann, S.4
Schuettler, W.5
Schuerholz, T.6
Mengel, M.7
Goudeva, L.8
Ganser, A.9
Klempnauer, J.10
Piepenbrock, S.11
Winkler, M.12
-
57
-
-
33746017989
-
Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells
-
DOI 10.1074/jbc.M600506200
-
Feistritzer C, Schuepbach RA, Mosnier LO, et al. Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells. J Biol Chem 2006; 281:20077-20084. (Pubitemid 44065782)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.29
, pp. 20077-20084
-
-
Feistritzer, C.1
Schuepbach, R.A.2
Mosnier, L.O.3
Bush, L.A.4
Di Cera, E.5
Griffin, J.H.6
Riewald, M.7
-
58
-
-
77951644463
-
Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model
-
Iba T, Nakarai E, Takayama T, et al. Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model. Crit Care 2009; 13:R203.
-
(2009)
Crit Care
, vol.13
-
-
Iba, T.1
Nakarai, E.2
Takayama, T.3
-
59
-
-
67649766887
-
Recombinant human soluble thrombomodulin decreases the plasma high-mobility group box-1 protein levels, whereas improving the acute liver injury and survival rates in experimental endotoxemia
-
Nagato M, Okamoto K, Abe Y, et al. Recombinant human soluble thrombomodulin decreases the plasma high-mobility group box-1 protein levels, whereas improving the acute liver injury and survival rates in experimental endotoxemia. Crit Care Med 2009; 37:2181-2186.
-
(2009)
Crit Care Med
, vol.37
, pp. 2181-2186
-
-
Nagato, M.1
Okamoto, K.2
Abe, Y.3
-
61
-
-
66249133355
-
Thrombomodulin improves early outcomes after intraportal islet transplantation
-
Cui W, Wilson JT, Wen J, et al. Thrombomodulin improves early outcomes after intraportal islet transplantation. Am J Transplant 2009; 9:1308-1316.
-
(2009)
Am J Transplant
, vol.9
, pp. 1308-1316
-
-
Cui, W.1
Wilson, J.T.2
Wen, J.3
-
62
-
-
70349569565
-
Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies
-
Seshan SV, Franzke CW, Redecha P, et al. Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies. Blood 2009; 114:1675-1683.
-
(2009)
Blood
, vol.114
, pp. 1675-1683
-
-
Seshan, S.V.1
Franzke, C.W.2
Redecha, P.3
-
63
-
-
1642407006
-
Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets
-
DOI 10.1097/01.TP.0000114872.26990.4F
-
Goto M, Johansson H, Maeda A, et al. Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets. Transplantation 2004; 77:741-747. (Pubitemid 38366981)
-
(2004)
Transplantation
, vol.77
, Issue.5
, pp. 741-747
-
-
Goto, M.1
Johansson, H.2
Maeda, A.3
Elgue, G.4
Korsgren, O.5
Nilsson, B.6
-
64
-
-
70349706907
-
Long-term controlled normoglycemia in diabetic nonhuman primates after transplantation with hCD46 transgenic porcine islets
-
Van der Windt DJ, Bottino R, Casu A, et al. Long-term controlled normoglycemia in diabetic nonhuman primates after transplantation with hCD46 transgenic porcine islets. Am J Transplant 2009; 9:2716-2726.
-
(2009)
Am J Transplant
, vol.9
, pp. 2716-2726
-
-
Van Der Windt, D.J.1
Bottino, R.2
Casu, A.3
-
65
-
-
34547610974
-
Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation
-
DOI 10.2337/db07-0358
-
Cabric S, Sanchez J, Lundgren T, et al. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation. Diabetes 2007; 56:2008-2015. (Pubitemid 47195827)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2008-2015
-
-
Cabric, S.1
Sanchez, J.2
Lundgren, T.3
Foss, A.4
Felldin, M.5
Kallen, R.6
Salmela, K.7
Tibell, A.8
Tufveson, G.9
Larsson, R.10
Korsgren, O.11
Nilsson, B.12
-
66
-
-
68249087180
-
Long-term metabolic control of autoimmune diabetes in spontaneously diabetic nonobese diabetic mice by nonvascularized microencapsulated adult porcine islets
-
Cui H, Tucker-Burden C, Cauffiel SM, et al. Long-term metabolic control of autoimmune diabetes in spontaneously diabetic nonobese diabetic mice by nonvascularized microencapsulated adult porcine islets. Transplantation 2009; 88:160-169.
-
(2009)
Transplantation
, vol.88
, pp. 160-169
-
-
Cui, H.1
Tucker-Burden, C.2
Cauffiel, S.M.3
-
67
-
-
73349108506
-
Pig islets for clinical islet xenotransplantation
-
Dufrane D, Gianello P. Pig islets for clinical islet xenotransplantation. Curr Opin Nephrol Hypertens 2009; 18:495-500.
-
(2009)
Curr Opin Nephrol Hypertens
, vol.18
, pp. 495-500
-
-
Dufrane, D.1
Gianello, P.2
-
68
-
-
58049221199
-
Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold
-
Berman DM, O'Neil JJ, Coffey LC, et al. Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant 2009; 9:91-104.
-
(2009)
Am J Transplant
, vol.9
, pp. 91-104
-
-
Berman, D.M.1
O'Neil, J.J.2
Coffey, L.C.3
-
70
-
-
70349657830
-
Endoscopic gastric submucosal transplantation of islets (ENDO-STI): Technique and initial results in diabetic pigs
-
Echeverri GJ, McGrath K, Bottino R, et al. Endoscopic gastric submucosal transplantation of islets (ENDO-STI): technique and initial results in diabetic pigs. Am J Transplant 2009; 9:2485-2496.
-
(2009)
Am J Transplant
, vol.9
, pp. 2485-2496
-
-
Echeverri, G.J.1
McGrath, K.2
Bottino, R.3
-
71
-
-
0036719075
-
The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor κB and mitogen-activated protein kinase pathways
-
DOI 10.1084/jem.20020077
-
Conway EM, Van de Wouwer M, Pollefeyt S, et al. The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappa B and mitogen-activated protein kinase pathways. J Exp Med 2002; 196:565-577. (Pubitemid 35024436)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.5
, pp. 565-577
-
-
Conway, E.M.1
Van De Wouwer, M.2
Pollefeyt, S.3
Jurk, K.4
Van Aken, H.5
De Vriese, A.6
Weitz, J.I.7
Weiler, H.8
Hellings, P.W.9
Schaeffer, P.10
Herbert, J.-M.11
Collen, D.12
Theilmeier, G.13
-
72
-
-
33746636356
-
The lectin-like domain of thrombomodulin interferes with complement activation and protects against arthritis
-
DOI 10.1111/j.1538-7836.2006.02033.x
-
Van de Wouwer M, Plaisance S, De Vriese A, et al. The lectin-like domain of thrombomodulin interferes with complement activation and protects against arthritis. J Thromb Haemost 2006; 4:1813-1824. (Pubitemid 44144810)
-
(2006)
Journal of Thrombosis and Haemostasis
, vol.4
, Issue.8
, pp. 1813-1824
-
-
Van De Wouwer, M.1
Plaisance, S.2
De Vriese, A.3
Waelkens, E.4
Collen, D.5
Persson, J.6
Daha, M.R.7
Conway, E.M.8
-
73
-
-
0032558117
-
Expression of human thrombomodulin cofactor activity in porcine endothelial cells
-
DOI 10.1097/00007890-199807270-00019
-
Kopp CW, Grey ST, Siegel JB, et al. Expression of human thrombomodulin cofactor activity in porcine endothelial cells. Transplantation 1998; 66:244-251. (Pubitemid 28370009)
-
(1998)
Transplantation
, vol.66
, Issue.2
, pp. 244-251
-
-
Kopp, C.W.1
Grey, S.T.2
Siegel, J.B.3
McShea, A.4
Vetr, H.5
Wrighton, C.J.6
Schulte Am Esch II, J.7
Bach, F.H.8
Robson, S.C.9
-
74
-
-
75149169244
-
Anti-inflammatory and anticoagulant effects of transgenic expression of human thrombomodulin in mice
-
Crikis S, Zhang XM, Dezfouli S, et al. Anti-inflammatory and anticoagulant effects of transgenic expression of human thrombomodulin in mice. Am J Transplant 2010; 10:242-250.
-
(2010)
Am J Transplant
, vol.10
, pp. 242-250
-
-
Crikis, S.1
Zhang, X.M.2
Dezfouli, S.3
-
75
-
-
77952257465
-
Transgenic pigs for xenotransplantation: Selection of promoter sequences for reliable transgene expression
-
Aigner B, Klymiuk N, Wolf E. Transgenic pigs for xenotransplantation: selection of promoter sequences for reliable transgene expression. Curr Opin Organ Transplant 2010; 15:201-206.
-
(2010)
Curr Opin Organ Transplant
, vol.15
, pp. 201-206
-
-
Aigner, B.1
Klymiuk, N.2
Wolf, E.3
-
76
-
-
12644288616
-
Identification and characterization of CD39/vascular ATP diphosphohydrolase
-
DOI 10.1074/jbc.271.51.33116
-
Kaczmarek E, Koziak K, Sevigny J, et al. Identification and characterization of CD39/vascular ATP diphosphohydrolase. J Biol Chem 1996; 271:33116-33122. (Pubitemid 27008752)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.51
, pp. 33116-33122
-
-
Kaczmarek, E.1
Koziak, K.2
Sevigny, J.3
Siegel, J.B.4
Anrather, J.5
Beaudoin, A.R.6
Bach, F.H.7
Robson, S.C.8
-
77
-
-
85047692190
-
Thromboregulatory manifestations in humanCD39transgenic mice and the implications for thrombotic disease and transplantation
-
Dwyer KM,Robson SC,Nandurkar HH, et al. Thromboregulatory manifestations in humanCD39transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest 2004; 113:1440-1446.
-
(2004)
J Clin Invest
, vol.113
, pp. 1440-1446
-
-
Dwyer, K.M.1
Robson, S.C.2
Nandurkar, H.H.3
-
78
-
-
33747115379
-
The transgenic expression of human CD39 on murine islets inhibits clotting of human blood
-
DOI 10.1097/01.tp.0000229023.38873.c0, PII 0000789020060815000022
-
Dwyer KM, Mysore TB, Crikis S, et al. The transgenic expression of human CD39 on murine islets inhibits clotting of human blood. Transplantation 2006; 82:428-432. (Pubitemid 44223045)
-
(2006)
Transplantation
, vol.82
, Issue.3
, pp. 428-432
-
-
Dwyer, K.M.1
Mysore, T.B.2
Crikis, S.3
Robson, S.C.4
Nandurkar, H.5
Cowan, P.J.6
D'Apice, A.J.F.7
-
79
-
-
78649867585
-
Transgenic overexpression of CD39 protects against renal ischemia-reperfusion and transplant vascular injury
-
Crikis S, Lu B, Murray-Segal LM, et al. Transgenic overexpression of CD39 protects against renal ischemia-reperfusion and transplant vascular injury. Am J Transplant 2010; 10:2586-2595.
-
(2010)
Am J Transplant
, vol.10
, pp. 2586-2595
-
-
Crikis, S.1
Lu, B.2
Murray-Segal, L.M.3
-
80
-
-
10044240662
-
Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium
-
DOI 10.1111/j.1600-6143.2004.00625.x
-
Chen D, Weber M, McVey JH, et al. Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium. Am J Transplant 2004; 4:1958-1963. (Pubitemid 39611622)
-
(2004)
American Journal of Transplantation
, vol.4
, Issue.12
, pp. 1958-1963
-
-
Chen, D.1
Weber, M.2
McVey, J.H.3
Kemball-Cook, G.4
Tuddenham, E.G.D.5
Lechler, R.I.6
Dorling, A.7
-
81
-
-
79952594087
-
Characterization of transgenic pigs that express human decay accelerating factor and cell membrane-tethered human tissue factor pathway inhibitor
-
DOI: 10.1111/j.1439-0531.2010.01670.x
-
Lee H, Lee B, Kim Y, et al. Characterization of transgenic pigs that express human decay accelerating factor and cell membrane-tethered human tissue factor pathway inhibitor. Reprod Domest Anim 2010; DOI: 10.1111/j.1439-0531. 2010.01670.x.
-
(2010)
Reprod Domest Anim
-
-
Lee, H.1
Lee, B.2
Kim, Y.3
|