Rejection of cardiac xenografts transplanted from α1,3- galactosyltransferase gene-knockout (GalT-KO) pigs to baboons

American Journal of Transplantation

Volumn 8, Issue 12, 2008, Pages 2516-2526

  Hisashi, Y ^a   Yamada, K ^a   Kuwaki, K ^a   Tseng, Y L ^a   Dor, F J M F ^a   Houser, S L ^a   Robson, S C ^b   Schuurman, H J ^c   Cooper, D K C ^a   Sachs, D H ^a   Colvin, R B ^a   Shimizu, A ^a,c,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Immerge Biotherapeutics Inc   (United States)

^d NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Acute rejection; Baboon; Cellular rejection; Chronic rejection; Humoral rejection; Xenotransplantation

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; CD3 ANTIGEN;

ACUTE GRAFT REJECTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL WALL THICKENING; ARTICLE; B LYMPHOCYTE; BABOON; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DAMAGE; CELL INFILTRATION; CHRONIC GRAFT REJECTION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; DISEASE COURSE; GRAFT FAILURE; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTOPATHOLOGY; HYPERACUTE GRAFT REJECTION; IMMUNOSUPPRESSIVE TREATMENT; INTRACARDIAC THROMBOSIS; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; VASCULAR DISEASE; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODY FORMATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; GALACTOSYLTRANSFERASES; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNITY, CELLULAR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; KILLER CELLS, NATURAL; PAPIO HAMADRYAS; SWINE; SWINE, MINIATURE; THROMBOSIS; TRANSPLANTATION, HETEROLOGOUS; TROPONIN T;

EID: 55949093773     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02444.x     Document Type: Article

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