HLA-Cw3 Expression on Porcine Endothelial Cells Protects Against Xenogeneic Cytotoxicity Mediated by a Subset of Human NK Cells

Journal of Immunology

Volumn 159, Issue 7, 1997, Pages 3655-3661

  Seebach, Jörg D ^a   Comrack, Christopher ^a   Germana, Sharon ^a   LeGuern, Christian ^a   Sachs, David H ^a   DerSimonian, Harout ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROPHILE ANTIGEN; HLA C ANTIGEN; HLA CW3 ANTIGEN; HLA-CW3; MEMBRANE ANTIGEN;

ANIMAL; ARTICLE; BIOSYNTHESIS; BONE MARROW CELL; CELL CLONE; CELL LINE; CLASSIFICATION; CYTOLOGY; CYTOTOXICITY; CYTOTOXICITY TEST; ENDOTHELIUM; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; NATURAL KILLER CELL; SWINE;

ANIMALS; ANTIGENS, HETEROPHILE; ANTIGENS, SURFACE; BONE MARROW CELLS; CELL LINE, TRANSFORMED; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; ENDOTHELIUM; HLA-C ANTIGENS; HUMANS; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; SWINE; TRANSFECTION;

EID: 0031253743     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
2. Moretta, L., E. Ciccone, M. C. Mingari, R. Biassoni, and A. Moretta. 1994. Human natural killer cells: origin, clonality, specificity, and receptors. Adv. Immunol. 55:341.
3. Ljunggren, H. G., and K. Kärre. 1990. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11:237.
4. Gumperz, J. E., and P. Parham. 1995. The enigma of the natural killer cell. Nature 378:245.
5. Lanier, L. L., and J. H. Phillips. 1996. Inhibitory MHC class I receptors on NK cells and T cells. Immunol. Today 17:86.
6. Moretta, A., C. Bottino, M. Vitale, D. Pende, R. Biassoni, M. C. Mingari, and L. Moretta. 1996. Receptors for HLA class-I molecules in human natural killer cells. Annu. Rev. Immunol. 14:619.
7. Döhring, C., D. Scheidegger, J. Samaridis, M. Cella, and M. Colonna. 1996. A human killer inhibitory receptor specific for HLA-A. J. Immunol. 156:3098.
8. Lanier, L. L., J. E. Gumperz, P. Parham, I. Melero, M. Lopez-Botet, and J. H. Phillips. 1995. The NKB1 and HP-3E4 NK cells receptors are structurally distinct glycoproteins and independently recognize polymorphic HLA-B and HLA-C molecules. J. Immunol. 154:3320.
9. Wagtmann, N., S. Rajagopalan, C. C. Winter, M. Peruzzi, and E. O. Long. 1995. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3:801.
10. Correa, I., L. Corral, and D. H. Raulet. 1994. Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur. J. Immunol. 24:1323.
11. Lanier, L. L. 1995. The role of natural killer cells in transplantation. Curr. Opin. Immunol. 7:626.
12. Bennett, M., Y. Y. Yu, E. Stoneman, R. M. Rembecki, P. A. Mathew, K. F. Lindahl, and V. Kumar. 1995. Hybrid resistance: "negative" and "positive" signaling of murine natural killer cells. Semin. Immunol. 7:121.
13. Kaufman, C. L., B. A. Gaines, and S. T. Ildstad. 1995. Xenotransplantation. Annu. Rev. Immunol. 13:339.
14. Bach, F. H., H. Winkler, C. Ferran, W. W. Hancock, and S. C. Robson. 1996. Delayed xenograft rejection. Immunol. Today 17:379.
15. Kirk, A. D., J. S. Heinle, J. R. Mault, and F. Sanfilippo. 1993. Ex vivo characterization of human anti-porcine hyperacute cardiac rejection. Transplantation 56:785.
16. Inverardi, L., and R. Pardi. 1994. Early events in cell-mediated recognition of vascularized xenografts: cooperative interactions between selected lymphocyte subsets and natural antibodies. Immunol. Rev. 141:71.
17. Goodman, D. J., M. Von Albertini, A. Willison, M. T. Millan, and F. H. Bach. 1996. Direct activation of porcine endothelial cells by human natural killer cells. Transplantation 61:763.
18. Blakely, M. L., W. J. Van der Werf, M. C. Berndt, A. P. Dalmasso, F. H. Bach, and W. W. Hancock. 1994. Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection. Transplantation 58:1059.
19. Kirk, A. D., R. A. Li, M. S. Kinch, K. A. Abernethy, C. Doyle, and R. R. Bollinger. 1993. The human antiporcine cellular repertoire: in vitro studies of acquired and innate cellular responsiveness. Transplantation 55:924.
20. Seebach, J. D., K. Yamada, I. McMorrow, D. H. Sachs, and H. DerSimonian. 1996. Xenogeneic human anti-pig cytotoxicity mediated by activated natural killer cells. Xenotransplantation 3:188.
21. Allavena, P., C. Paganin, I. Martin-Padura, G. Peri, M. Gaboli, E. Dejana, P. C. Marchisio, and A. Mantovani. 1991. Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium. J. Exp. Med. 173:439.
22. Lowdell, M. W., F. Shamim, M. Hamon, I. D. Macdonald, and H. G. Prentice. 1995. VLA-6 (CDw49f) is an important adhesion molecule in NK cell-mediated cytotoxicity following autologous or allogeneic bone marrow transplantation. Exp. Hematol. 23:1530.
23. Paguio, C. P., S. Germana, C. LeGuern, B. A. Julian, D. H. Sachs, and D. W. Emery. 1996. Derivation of immortalized swine stromal cell lines. Transplant. Proc. 28:791.
24. Koller, B. H., and H. T. Orr. 1985. Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level. J. Immunol. 134: 2727.
25. Taurog, J. D., L. Lowen, J. Forman, and R. E. Hammer. 1988. HLA-B27 in inbred and non-inbred transgenic mice: cell surface expression and recognition as an alloantigen in the absence of human beta 2-microglobulin. J. Immunol. 141: 4020.
26. Sodoyer, R., M. Damotte, T. L. Delovitch, J. Trucy, B. R. Jordan, and T. Strachan. 1984. Complete nucleotide sequence of a gene encoding a functional human class I histocompatibility antigen (HLA-CW3). EMBO J. 3:879.
27. Barnstable, C. J., W. F. Bodmer, G. Brown, B. B. Galfre, C. Milstein, A. F. Williams, and A. Ziegler. 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens: new tools for genetic analysis. Cell 14:9.
28. Ivansoka, D., D. C. Sun, and J. K. Lunney. 1991. Production of monoclonal antibodies reactive with polymorphic and monomorphic determinants of SLA class I gene products. Immunogenetics 33:220.
29. Mizuno, S., S. H. Kang, H. W. Lee, J. A. Trapani, B. Dupont, and S. Y. Yang. 1989. Isolation and expression of cDNA clone encoding HLA-Cw6: unique characteristics of HLA-C-encoded gene products. Immunogenetics 29:323.
30. Malnati, M. S., P. Lusso, E. Ciccone, A. Moretta, L. Moretta, and E. O. Long. 1993. Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements. J. Exp. Med. 178:961.
31. Robertson, M. J., T. J. Manley, C. Donahue, H. Levine, and J. Ritz. 1993. Costimulatory signals are required for optimal proliferation of human natural killer cells. J. Immunol. 150:1705.
32. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M. S. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E. O. Long. 1995. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra-and intracellular domains. Immunity 2:439.
33. Watkins, D. I. 1995. The evolution of major histocompatibility class I genes in primates. Crit. Rev. Immunol. 15:1.
34. Malnati, M. S., M. Peruzzi, K. C. Parker, W. E. Biddison, E. Ciccone, A. Moretta, and E. O. Long. 1995. Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science 267:1016.
35. Correa, I., and D. H. Raulet. 1995. Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity 2:61.
36. Madden, D. R. 1995. The three-dimensional structure of peptide-MHC complexes. Annu. Rev. Immunol. 13:587.
37. Mandelboim, O., H. T. Reyburn, M. Valés-Gómez, L. Pazmany, M. Colonna, G. Borsellino, and J. L. Strominger. 1996. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. J. Exp. Med. 184:913.
38. Kärre, K. 1995. Express yourself or die: peptides, MHC molecules, and NK cells. Science 267:978.
39. Sachs, D. H. 1994. The pig as a potential xenograft donor. Pathol. Biol. 42:217.
40. Pazmany, L., O. Mandelboim, M. Vales-Gomez, D. M. Davis, H. T. Reyburn, and J. L. Strominger. 1996. Protection from natural killer cell mediated lysis by HLA-G expression on target cells. Science 274:792.