메뉴 건너뛰기




Volumn 104, Issue 3, 1999, Pages 281-290

Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Galα1,3Gal-mediated graft rejection

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSYLTRANSFERASE;

EID: 0032728567     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI6656     Document Type: Article
Times cited : (114)

References (52)
  • 1
    • 0030271853 scopus 로고    scopus 로고
    • Xenotransplantation: Recent progress and current perspectives
    • Platt, J.L. 1996. Xenotransplantation: recent progress and current perspectives. Curr. Opin. Immunol. 8:721-728.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 721-728
    • Platt, J.L.1
  • 2
    • 0028399233 scopus 로고
    • The pig as a xenograft donor
    • Sachs, D.H. 1994. The pig as a xenograft donor Pathol. Biol. 42:217-219.
    • (1994) Pathol. Biol. , vol.42 , pp. 217-219
    • Sachs, D.H.1
  • 3
    • 0027716847 scopus 로고
    • Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation
    • Oriol, R., Ye, Y., Koren, E., and Cooper, D.K.C. 1993. Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation. Transplantation. 56:1413-1442.
    • (1993) Transplantation , vol.56 , pp. 1413-1442
    • Oriol, R.1    Ye, Y.2    Koren, E.3    Cooper, D.K.C.4
  • 4
    • 0027508081 scopus 로고
    • Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans
    • Galili, U. 1993. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans. Immunol. Today. 14:480-482.
    • (1993) Immunol. Today , vol.14 , pp. 480-482
    • Galili, U.1
  • 5
    • 0027517325 scopus 로고
    • Anti-pig IgM antibodies in human serum react predominantly with Galα1-3Gal epitopes
    • Sandrin, M., Vaughan, H.A., Dabkowski, P.L., and McKenzie, I.F.C. 1993. Anti-pig IgM antibodies in human serum react predominantly with Galα1-3Gal epitopes. Proc. Natl. Acad. Sci. USA. 90:11391-11395.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11391-11395
    • Sandrin, M.1    Vaughan, H.A.2    Dabkowski, P.L.3    McKenzie, I.F.C.4
  • 6
    • 0027480563 scopus 로고
    • Prolongation of cardiac xenograft survival by depletion of complement
    • Leventhal, J.R., et al. 1993. Prolongation of cardiac xenograft survival by depletion of complement. Transplantation. 55:857-865.
    • (1993) Transplantation , vol.55 , pp. 857-865
    • Leventhal, J.R.1
  • 7
    • 0029068597 scopus 로고
    • The generation of transgenic pigs as potential organ donors for humans
    • Cozzi, E., and White, D.J.G 1995. The generation of transgenic pigs as potential organ donors for humans. Nat. Med. 1:964-967.
    • (1995) Nat. Med. , vol.1 , pp. 964-967
    • Cozzi, E.1    White, D.J.G.2
  • 8
    • 0029175941 scopus 로고
    • Xenotransplantation of pig kidneys to nonhuman primates: I. Development of a model
    • Sablinski, T., et al. 1995. Xenotransplantation of pig kidneys to nonhuman primates: I. Development of a model. Xenotransplantation. 2:264-270.
    • (1995) Xenotransplantation , vol.2 , pp. 264-270
    • Sablinski, T.1
  • 9
    • 0032518991 scopus 로고    scopus 로고
    • Intravenous infusion of Galα1-3Gal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenografts
    • Simon, P.M., et al. 1998. Intravenous infusion of Galα1-3Gal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenografts. Transplantation. 65:346-353.
    • (1998) Transplantation , vol.65 , pp. 346-353
    • Simon, P.M.1
  • 10
    • 0028811673 scopus 로고
    • Enzymatic remodelling of the carbohydrate surface of a xenogeneic cell substantially reduces human antibody binding and complement-mediated cytolysis
    • Sandrin, M.S., et al. 1995. Enzymatic remodelling of the carbohydrate surface of a xenogeneic cell substantially reduces human antibody binding and complement-mediated cytolysis. Nat. Med. 1:1261-1267.
    • (1995) Nat. Med. , vol.1 , pp. 1261-1267
    • Sandrin, M.S.1
  • 11
    • 0031460988 scopus 로고    scopus 로고
    • Combined transgenic expression of α-galactosidase and α1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galα(1,3)Gal
    • Osman, N., et al. 1998. Combined transgenic expression of α-galactosidase and α1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galα(1,3)Gal. Proc. Natl. Acad. Sci. USA. 94:14677-14682.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14677-14682
    • Osman, N.1
  • 12
    • 0031931624 scopus 로고    scopus 로고
    • Xenoantigens and xenoantibodies
    • Cooper, D.K.C. 1998. Xenoantigens and xenoantibodies. Xenotransplantation. 5:6-17.
    • (1998) Xenotransplantation , vol.5 , pp. 6-17
    • Cooper, D.K.C.1
  • 13
    • 0001458942 scopus 로고    scopus 로고
    • High-affinity anti-Gal immunoglobulin G in chronic rejection of xenografts
    • Galili, U., Minanov, O.P., Michler, R.E., and Stone, K.R 1997. High-affinity anti-Gal immunoglobulin G in chronic rejection of xenografts. Xenotransplantation. 4:127-131.
    • (1997) Xenotransplantation , vol.4 , pp. 127-131
    • Galili, U.1    Minanov, O.P.2    Michler, R.E.3    Stone, K.R.4
  • 14
    • 0032571264 scopus 로고    scopus 로고
    • α-galactosyl epitope-mediated activation of porcine aortic endothelial cells
    • Palmetshofer, A., Galili, U., Dalmasso, A.P., Robson, S.C., and Bach, F.H. 1998. α-galactosyl epitope-mediated activation of porcine aortic endothelial cells. Transplantation. 65:844-853.
    • (1998) Transplantation , vol.65 , pp. 844-853
    • Palmetshofer, A.1    Galili, U.2    Dalmasso, A.P.3    Robson, S.C.4    Bach, F.H.5
  • 15
    • 0029078508 scopus 로고
    • Barriers to xenotransplantation
    • Bach, F.H., et al. 1995. Barriers to xenotransplantation. Nat. Med. 1:869-873.
    • (1995) Nat. Med. , vol.1 , pp. 869-873
    • Bach, F.H.1
  • 16
    • 0031906108 scopus 로고    scopus 로고
    • Induction of specific transplantation tolerance across xenogeneic barriers in the T-independent immune compartment
    • Lin, Y., Goebels, J., Xia, G., Vandeputte, M., and Waer, M. 1998. Induction of specific transplantation tolerance across xenogeneic barriers in the T-independent immune compartment. Nat. Med. 4:173-180.
    • (1998) Nat. Med. , vol.4 , pp. 173-180
    • Lin, Y.1    Goebels, J.2    Xia, G.3    Vandeputte, M.4    Waer, M.5
  • 17
    • 0031931570 scopus 로고    scopus 로고
    • Accommodation and T-independent B cell tolerance in rats with long term surviving hamster heart xenografts
    • Lin, Y., Vandeputte, M., and Waer, M. 1998. Accommodation and T-independent B cell tolerance in rats with long term surviving hamster heart xenografts. J. Immunol. 160:369-375.
    • (1998) J. Immunol. , vol.160 , pp. 369-375
    • Lin, Y.1    Vandeputte, M.2    Waer, M.3
  • 18
    • 0031688001 scopus 로고    scopus 로고
    • Adult and neonatal anti-Gal response in knock-out mice for α1,3galactosyltransferase
    • LaTemple, D.C., and Galili, U. 1998. Adult and neonatal anti-Gal response in knock-out mice for α1,3galactosyltransferase. Xenotransplantation. 5:191-196.
    • (1998) Xenotransplantation , vol.5 , pp. 191-196
    • LaTemple, D.C.1    Galili, U.2
  • 19
    • 0032549859 scopus 로고    scopus 로고
    • Tolerization of anti-Galα1-3Gal natural antibody-forming B cells by induction of mixed chimerism
    • Yang, Y.-G., et al. 1998. Tolerization of anti-Galα1-3Gal natural antibody-forming B cells by induction of mixed chimerism. J. Exp. Med. 187:1335-1342.
    • (1998) J. Exp. Med. , vol.187 , pp. 1335-1342
    • Yang, Y.-G.1
  • 20
    • 0028982258 scopus 로고
    • Oocyte Galα1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse
    • Thall, A.D., Maly, P., and Lowe, J.B. 1995, Oocyte Galα1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse. J. Biol. Cbem. 270:21437-21440.
    • (1995) J. Biol. Cbem. , vol.270 , pp. 21437-21440
    • Thall, A.D.1    Maly, P.2    Lowe, J.B.3
  • 21
    • 0021052516 scopus 로고
    • Characterization of murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: Similarity of L3T4 to human Leu3/T4 molecule
    • Dialynas, D.P., et al. 1983. Characterization of murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to human Leu3/T4 molecule. J. Immunol. 131:2445-2451.
    • (1983) J. Immunol. , vol.131 , pp. 2445-2451
    • Dialynas, D.P.1
  • 22
    • 0019218668 scopus 로고
    • IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt2 antigen block T cell-mediated cytolysis in the absence of complement
    • Sarmiento, M., Glasebrook, A.L., and Fitch, F.W. 1980. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125:2665-2672.
    • (1980) J. Immunol. , vol.125 , pp. 2665-2672
    • Sarmiento, M.1    Glasebrook, A.L.2    Fitch, F.W.3
  • 23
    • 0024561069 scopus 로고
    • Mixed chimerism and permanent specific transplantation tolerance induced by a non-lethal preparative regimen
    • Sharabi, Y., and Sachs, D.H. 1989. Mixed chimerism and permanent specific transplantation tolerance induced by a non-lethal preparative regimen. J. Exp. Med. 169:493-502.
    • (1989) J. Exp. Med. , vol.169 , pp. 493-502
    • Sharabi, Y.1    Sachs, D.H.2
  • 24
    • 0027465449 scopus 로고
    • IL-2 reduces graft-vs-host disease and preserves a graft-vs-leukemia effect by selectively inhibiting CD4' T cell activity
    • Sykes, M., Abraham, V.S., Harty, M.W., and Pearson, D.A. 1993. IL-2 reduces graft-vs-host disease and preserves a graft-vs-leukemia effect by selectively inhibiting CD4' T cell activity. J. Immunol. 150:197-205.
    • (1993) J. Immunol. , vol.150 , pp. 197-205
    • Sykes, M.1    Abraham, V.S.2    Harty, M.W.3    Pearson, D.A.4
  • 25
    • 0028341472 scopus 로고
    • Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a non-myeloablative regimen
    • Tomita, Y., Khan, A., and Sykes, M. 1994. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a non-myeloablative regimen. J. Immunol. 153:1087-1098.
    • (1994) J. Immunol. , vol.153 , pp. 1087-1098
    • Tomita, Y.1    Khan, A.2    Sykes, M.3
  • 27
    • 0025828568 scopus 로고
    • Simplified mouse cervical heart transplantation using a cuff technique
    • Matsuura, A., Abe, T., and Yasuura, K. 1991. Simplified mouse cervical heart transplantation using a cuff technique. Transplantation. 51:896-898.
    • (1991) Transplantation. , vol.51 , pp. 896-898
    • Matsuura, A.1    Abe, T.2    Yasuura, K.3
  • 28
    • 0026047082 scopus 로고
    • Natural antibody against bone marrow cells of a concordant xenogeneic species. J
    • Aksentijevich, I., Sachs, D.H., and Sykes, M. 1991. Natural antibody against bone marrow cells of a concordant xenogeneic species. J. Immunol. 147:79-85.
    • (1991) Immunol. , vol.147 , pp. 79-85
    • Aksentijevich, I.1    Sachs, D.H.2    Sykes, M.3
  • 29
    • 0021678856 scopus 로고
    • A unique natural human IgG antibody with anti-galactosyl specificity
    • Galili, U., Rachmilewitz, E.A., Peleg, A., and Flechner, I. 1984. A unique natural human IgG antibody with anti-galactosyl specificity. J. Exp. Med. 16:1519-1531.
    • (1984) J. Exp. Med. , vol.16 , pp. 1519-1531
    • Galili, U.1    Rachmilewitz, E.A.2    Peleg, A.3    Flechner, I.4
  • 30
    • 0032556895 scopus 로고    scopus 로고
    • Transgenic pigs and virus adaptation
    • Weiss, R.A. 1998. Transgenic pigs and virus adaptation. Nature. 391:327-328.
    • (1998) Nature , vol.391 , pp. 327-328
    • Weiss, R.A.1
  • 31
    • 0026333473 scopus 로고
    • Natural antibodies can inhibit bone marrow engraftment in the rat→mouse species combination
    • Aksentijevich, I., Sachs, D.H., and Sykes, M. 1991. Natural antibodies can inhibit bone marrow engraftment in the rat→mouse species combination. J. Immunol. 147:4140-4146.
    • (1991) J. Immunol. , vol.147 , pp. 4140-4146
    • Aksentijevich, I.1    Sachs, D.H.2    Sykes, M.3
  • 32
    • 0026623563 scopus 로고
    • Humoral tolerance in xenogeneic BMT recipients conditioned with a non-myeloablative regimen
    • Aksentijevich, I., Sachs, D.H., and Sykes, M. 1992. Humoral tolerance in xenogeneic BMT recipients conditioned with a non-myeloablative regimen. Transplantation. 53:1108-1114.
    • (1992) Transplantation , vol.53 , pp. 1108-1114
    • Aksentijevich, I.1    Sachs, D.H.2    Sykes, M.3
  • 33
    • 0028209319 scopus 로고
    • The importance of non-immune factors in reconstitution by discordant xenogeneic hematopoietic ceils
    • G ritsch, H.A., et al. 1994. The importance of non-immune factors in reconstitution by discordant xenogeneic hematopoietic ceils. Transplantation. 57:906-917.
    • (1994) Transplantation , vol.57 , pp. 906-917
    • Gritsch, H.A.1
  • 34
    • 4243160119 scopus 로고    scopus 로고
    • Donor-specific growth factors promote swine hematopoiesis in SCID mice
    • Yang, Y.-G., et al. 1996. Donor-specific growth factors promote swine hematopoiesis in SCID mice. Xenotransplantation. 3:92-101.
    • (1996) Xenotransplantation , vol.3 , pp. 92-101
    • Yang, Y.-G.1
  • 35
    • 0016529140 scopus 로고
    • Radiosensitivity of T and B lymphocytes. III. Effect of radiation on immunoglobulin production by B cells
    • Anderson, R.E., and Warner, N.L. 1975. Radiosensitivity of T and B lymphocytes. III. Effect of radiation on immunoglobulin production by B cells. J. Immunol. 115:161-169.
    • (1975) J. Immunol. , vol.115 , pp. 161-169
    • Anderson, R.E.1    Warner, N.L.2
  • 36
    • 0032033127 scopus 로고    scopus 로고
    • Humoral immunity due to long-lived plasma cells
    • Slifka, M.K., Antia, R., Whitmire, J.K., and Ahmed, R. 1998. Humoral immunity due to long-lived plasma cells. Immunity. 8:363-372.
    • (1998) Immunity , vol.8 , pp. 363-372
    • Slifka, M.K.1    Antia, R.2    Whitmire, J.K.3    Ahmed, R.4
  • 37
    • 0031003643 scopus 로고    scopus 로고
    • Influences on the lifespan of B cell subpopulations defined by different phenotypes
    • Fulcher, D.A., and Basten, A. 1997. Influences on the lifespan of B cell subpopulations defined by different phenotypes. Eur. J. Immunol. 27:1188-1199.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1188-1199
    • Fulcher, D.A.1    Basten, A.2
  • 38
    • 0030250062 scopus 로고    scopus 로고
    • The "clonal selection hypothesis" and current concepts of B cell tolerance
    • Klinman, N.R. 1996. The "clonal selection hypothesis" and current concepts of B cell tolerance. Immunity. 5:189-195.
    • (1996) Immunity , vol.5 , pp. 189-195
    • Klinman, N.R.1
  • 39
    • 0026559216 scopus 로고
    • Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
    • Murakami, M., et al. 1992. Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature. 357:77-80.
    • (1992) Nature , vol.357 , pp. 77-80
    • Murakami, M.1
  • 40
    • 0026041119 scopus 로고
    • Peripheral deletion of self-reactive B-cells
    • Russell, D.M., et al. 1991. Peripheral deletion of self-reactive B-cells. Nature. 354:308-311.
    • (1991) Nature , vol.354 , pp. 308-311
    • Russell, D.M.1
  • 41
    • 0009927162 scopus 로고
    • Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc
    • Nemazee, D., and Buerki, K. 1989. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc. Natl. Acad. Sci. USA. 86:8039-8043.
    • (1989) Natl. Acad. Sci. USA , vol.86 , pp. 8039-8043
    • Nemazee, D.1    Buerki, K.2
  • 42
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S.B., et al. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature. 353:765-769.
    • (1991) Nature , vol.353 , pp. 765-769
    • Hartley, S.B.1
  • 43
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B-lymphocytes in transgenic mice
    • Goodnow, C.C., et al. 1988. Altered immunoglobulin expression and functional silencing of self-reactive B-lymphocytes in transgenic mice. Nature. 334:676-682.
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1
  • 44
    • 0029936944 scopus 로고    scopus 로고
    • Clonal anergy of B cells: A flexible, reversible, and quantitative concept
    • Nossal, G.J.V. 1996. Clonal anergy of B cells: a flexible, reversible, and quantitative concept. J. Exp. Med. 183:1953-1956.
    • (1996) J. Exp. Med. , vol.183 , pp. 1953-1956
    • Nossal, G.J.V.1
  • 45
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B-cells
    • Tiegs, S., Russell, D., and Nemazee, D. 1993. Receptor editing in self-reactive bone marrow B-cells. J. Exp. Med. 177:1009-1020.
    • (1993) J. Exp. Med. , vol.177 , pp. 1009-1020
    • Tiegs, S.1    Russell, D.2    Nemazee, D.3
  • 46
    • 0030981639 scopus 로고    scopus 로고
    • - bone marrow B cells in vitro
    • - bone marrow B cells in vitro. Immunity. 6:429-438.
    • (1997) Immunity , vol.6 , pp. 429-438
    • Hertz, M.1    Nemazee, D.2
  • 47
    • 0031424315 scopus 로고    scopus 로고
    • Receptor editing in a transgenic mouse model: Site, efficiency, and role in B cell tolerance and antibody diversification
    • Pelanda, R., et al. 1997. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7:765-775.
    • (1997) Immunity , vol.7 , pp. 765-775
    • Pelanda, R.1
  • 48
    • 0023950859 scopus 로고
    • Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon
    • Cooper, D.K.C., et al. 1988. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon. J. Heart Transplant. 7:238-246.
    • (1988) J. Heart Transplant. , vol.7 , pp. 238-246
    • Cooper, D.K.C.1
  • 50
    • 0032572979 scopus 로고    scopus 로고
    • Anti-gal antibody-mediated allograft rejection in α1,3-galactosyltransferase gene knockout mice. A model of delayed xenograft rejection
    • Pearse, M., et al. 1998. Anti-gal antibody-mediated allograft rejection in α1,3-galactosyltransferase gene knockout mice. A model of delayed xenograft rejection. Transplantation. 66:748-754.
    • (1998) Transplantation , vol.66 , pp. 748-754
    • Pearse, M.1
  • 51
    • 0025284544 scopus 로고
    • Specific tolerance induction across a xenogeneic barrier: Production of mixed rat/mouse lymphohemaropoietic chimeras using a non-lethal preparative regimen
    • Sharabi, Y., Aksentijevich, I., Sundt, T.M., III, Sachs, D.H., and Sykes, M. 1990. Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohemaropoietic chimeras using a non-lethal preparative regimen. J. Exp. Med. 172:195-202.
    • (1990) J. Exp. Med. , vol.172 , pp. 195-202
    • Sharabi, Y.1    Aksentijevich, I.2    Sundt T.M. III3    Sachs, D.H.4    Sykes, M.5
  • 52
    • 0029963434 scopus 로고    scopus 로고
    • Skin graft tolerance across a discordant xenogeneic barrier
    • Zhao, Y., et al. 1996. Skin graft tolerance across a discordant xenogeneic barrier. Nat. Med. 2:1211-1216.
    • (1996) Nat. Med. , vol.2 , pp. 1211-1216
    • Zhao, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.