Human monoclonal HLA antibodies reveal interspecies crossreactive swine MHC class I epitopes relevant for xenotransplantation

Molecular Immunology

Volumn 47, Issue 4, 2010, Pages 809-815

  Mulder, Arend ^a   Kardol, Marrie J ^a   Arn, J Scott ^b   Eijsink, Chantal ^a   Franke, Marry E I ^a   Schreuder, Geziena M T ^a   Haasnoot, Geert W ^a   Doxiadis, Ilias I N ^a   Sachs, David H ^b   Smith, Douglas M ^c   Claas, Frans H J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Hyperacute rejection; MHC; Monoclonal antibodies; SLA; Swine; Xenotransplantation

Indexed keywords

EPITOPE; HLA ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SWINE LEUKOCYTE ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN BINDING; ARTICLE; CROSS REACTION; DONOR SELECTION; FEMALE; GENETIC POLYMORPHISM; HAPLOTYPE; HUMAN; LYMPHOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGAN DONOR; PRIORITY JOURNAL; SWINE; XENOTRANSPLANTATION;

ALLELES; ANIMALS; ANTIBODIES, MONOCLONAL; CROSS REACTIONS; CYTOTOXICITY TESTS, IMMUNOLOGIC; EPITOPES; FLOW CYTOMETRY; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MICE; SPECIES SPECIFICITY; SUS SCROFA; TRANSPLANTATION, HETEROLOGOUS;

SUIDAE;

EID: 72949095170     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.10.004     Document Type: Article

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