Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: Implications for xenotransplantation in infants

Transplant International

Volumn 20, Issue 12, 2007, Pages 1050-1058

  Rood, Pleunie P M ^a,b,c   Tai, Hao Chih ^a   Hara, Hidetaka ^a   Long, Cassandra ^a   Ezzelarab, Mohamed ^a   Lin, Yih J ^a   Van Der Windt, Dirk J ^a,b,c   Busch, Jamie ^a   Ayares, David ^d   Ijzermans, Jan N M ^c   Wolf, Roman F ^e   Manji, Rizwan ^f,h   Bailey, Leonard ^g   Cooper, David K C ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d REVIVICOR INC   (United States)

^e UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^f UNIVERSITY OF ALBERTA   (Canada)

^g LOMA LINDA UNIVERSITY   (United States)

^h UNIVERSITY OF MANITOBA   (Canada)

Author keywords

1,3 galactosyltransferase gene knockout; Anti pig antibodies; Infants; Primates; Xenotransplantation

Indexed keywords

ANTIBODY; BLOOD GROUP ANTIBODY; COMPLEMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ANIMAL CELL; ARTICLE; BABOON; CELL TRANSPLANTATION; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; NONHUMAN; ORGAN TRANSPLANTATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SERUM; SWINE; XENOTRANSPLANTATION;

ABO BLOOD-GROUP SYSTEM; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODY FORMATION; CHILD DEVELOPMENT; CYTOTOXICITY TESTS, IMMUNOLOGIC; FLOW CYTOMETRY; GALACTOSYLTRANSFERASES; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; INFANT, NEWBORN; LEUKOCYTES, MONONUCLEAR; MODELS, ANIMAL; PAPIO; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 35748931149     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2007.00546.x     Document Type: Article

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