Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status

Immunology

Volumn 140, Issue 1, 2013, Pages 39-46

  Hara, Hidetaka ^a   Witt, William ^a   Crossley, Tanner ^a   Long, Cassandra ^a   Isse, Kumiko ^a   Fan, Liming ^b   Phelps, Carol J ^c   Ayares, David ^c   Cooper, David K C ^a   Dai, Yifan ^b   Starzl, Thomas E ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c REVIVICOR INC   (United States)

Author keywords

Genetic engineering; Immune response; MHC class II transactivator; Pig; Swine leucocyte antigens; Xenotransplantation

Indexed keywords

ANGIOPOIETIN RECEPTOR; LEUKOCYTE ANTIGEN; MESSENGER RNA; SWINE LEUCOCYTE ANTIGEN CLASS II; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL NUCLEUS TRANSPLANTATION; CELLULAR IMMUNITY; CLASS II TRANSACTIVATOR; CONTROLLED STUDY; EMBRYO TRANSFER; ENDOTHELIUM CELL; ENHANCER REGION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE; TRANSGENE; TRANSGENIC PIG; WILD TYPE;

GENETIC ENGINEERING; IMMUNE RESPONSE; MHC CLASS II TRANSACTIVATOR; PIG; SWINE LEUCOCYTE ANTIGENS; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, HETEROPHILE; CD4-POSITIVE T-LYMPHOCYTES; GENE EXPRESSION; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LYMPHOCYTE ACTIVATION; NUCLEAR PROTEINS; RNA, MESSENGER; SUS SCROFA; TRANS-ACTIVATORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84883235507     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12107     Document Type: Article

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