Transgenic expression of human signal regulatory protein alpha in Rag2 -/-γ c -/- mice improves engraftment of human hematopoietic cells in humanized mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 32, 2011, Pages 13218-13223

  Strowig, Till ^a   Rongvaux, Anthony ^a   Rathinam, Chozhavendan ^a   Takizawa, Hitoshi ^a,b,c   Borsotti, Chiara ^a,b,c   Philbrick, William ^a   Eynon, Elizabeth E ^a   Manz, Markus G ^a,b,c   Flavell, Richard A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

Author keywords

CD34 + cell; Xenorejection

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; RAG2 PROTEIN; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; ENGRAFTMENT; GENE EXPRESSION; GENETIC ENGINEERING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; IMMUNE SYSTEM; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, DIFFERENTIATION; BONE MARROW CELLS; CELL LINEAGE; DNA-BINDING PROTEINS; EPITOPES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNITY, HUMORAL; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, IMMUNOLOGIC; TRANSGENES;

MURINAE; MUS;

EID: 80051988436     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109769108     Document Type: Article

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