메뉴 건너뛰기




Volumn , Issue , 2012, Pages 93-117

The role of microglia in neurodegenerative disease

Author keywords

Microglia; Neurodegeneration; Neuroinflammation; Neurology; PK11195

Indexed keywords


EID: 84892964983     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (1)

References (195)
  • 1
    • 0035833937 scopus 로고    scopus 로고
    • Immune reactivity in a mouse model of familial ALS correlates with disease progression
    • Alexianu ME, Kozovska M, Appel SH. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 2001; 57 (7): 1282-1289.
    • (2001) Neurology , vol.57 , Issue.7 , pp. 1282-1289
    • Alexianu, M.E.1    Kozovska, M.2    Appel, S.H.3
  • 2
    • 0032737272 scopus 로고    scopus 로고
    • Microglia derive from progenitors originating from the yoc sac and which proliferate in the brain
    • Alliot F, Godin I, Pessac B. Microglia derive from progenitors originating from the yoc sac and which proliferate in the brain. Brain Res. 1999; 117: 145-152.
    • (1999) Brain Res. , vol.117 , pp. 145-152
    • Alliot, F.1    Godin, I.2    Pessac, B.3
  • 4
    • 0035152836 scopus 로고    scopus 로고
    • Immune function of microglia
    • Aloisi F. Immune function of microglia. Glia. 2001; 36 (2): 165-179.
    • (2001) Glia. , vol.36 , Issue.2 , pp. 165-179
    • Aloisi, F.1
  • 6
    • 0034044177 scopus 로고    scopus 로고
    • A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration
    • Armstrong RA, Cairns NJ, Lantos PL. A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration. Exp. Neurol. 2000; 163 (2): 348-356.
    • (2000) Exp. Neurol. , vol.163 , Issue.2 , pp. 348-356
    • Armstrong, R.A.1    Cairns, N.J.2    Lantos, P.L.3
  • 7
    • 0041319041 scopus 로고    scopus 로고
    • Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
    • Babcock AA, Kuziel WA, Rivest S, Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J. Neurosci 2003; 23 (21): 7922-7930.
    • (2003) J. Neurosci , vol.23 , Issue.21 , pp. 7922-7930
    • Babcock, A.A.1    Kuziel, W.A.2    Rivest, S.3    Owens, T.4
  • 9
    • 0031930771 scopus 로고    scopus 로고
    • Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease
    • Banati RB, Daniel SE, Blunt SB. Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease. Mov. Disord.1998; 13: 221-227.
    • (1998) Mov. Disord. , vol.13 , pp. 221-227
    • Banati, R.B.1    Daniel, S.E.2    Blunt, S.B.3
  • 12
    • 0001710321 scopus 로고    scopus 로고
    • MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS)
    • Barkhof F. MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS). Mult Scler 1999; 5 (4): 283-286.
    • (1999) Mult Scler , vol.5 , Issue.4 , pp. 283-286
    • Barkhof, F.1
  • 13
    • 0036260539 scopus 로고    scopus 로고
    • The clinico-radiological paradox in multiple sclerosis revisited
    • Barkhof F. The clinico-radiological paradox in multiple sclerosis revisited. Curr. Opin Neurol. 2002; 15 (3): 239-245.
    • (2002) Curr. Opin Neurol. , vol.15 , Issue.3 , pp. 239-245
    • Barkhof, F.1
  • 14
    • 0033276595 scopus 로고    scopus 로고
    • Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) disease
    • Barnum SR. Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) disease. Mol. Med 1999; 5 (9): 569-582.
    • (1999) Mol. Med , vol.5 , Issue.9 , pp. 569-582
    • Barnum, S.R.1
  • 15
  • 16
    • 3142655659 scopus 로고    scopus 로고
    • Microglia kill amyloid-beta1-42 damaged neurons by a CD14-dependent process
    • Bate C, Veerhuis R, Eikelenboom P, Williams A. Microglia kill amyloid-beta1-42 damaged neurons by a CD14-dependent process. Neuroreport 2004; 15 (9): 1427-1430.
    • (2004) Neuroreport , vol.15 , Issue.9 , pp. 1427-1430
    • Bate, C.1    Veerhuis, R.2    Eikelenboom, P.3    Williams, A.4
  • 17
    • 0028339366 scopus 로고
    • Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis.J
    • Bauer J, Sminia T, Wouterlood FG, Dijkstra CD. Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis.J. Neurosci. Res. 1994; 38 (4): 365-375.
    • (1994) Neurosci. Res. , vol.38 , Issue.4 , pp. 365-375
    • Bauer, J.1    Sminia, T.2    Wouterlood, F.G.3    Dijkstra, C.D.4
  • 19
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis.J
    • Benveniste EN. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis.J. Mol. Med. (Berl) 1997; 75 (3): 165-173.
    • (1997) Mol. Med. (Berl) , vol.75 , Issue.3 , pp. 165-173
    • Benveniste, E.N.1
  • 21
    • 0030037586 scopus 로고    scopus 로고
    • Beta-amyloid peptide secretion by a microglial cell line is induced by beta-amyloid-(25-35) and lipopolysaccharide
    • Bitting L, Naidu A, Cordell B, Murphy GM Jr. Beta-amyloid peptide secretion by a microglial cell line is induced by beta-amyloid-(25-35) and lipopolysaccharide. J. Biol. Chem. 1996; 271(27): 16084-16089.
    • (1996) J. Biol. Chem. , vol.271 , Issue.27 , pp. 16084-16089
    • Bitting, L.1    Naidu, A.2    Cordell, B.3    Murphy Jr, G.M..4
  • 23
    • 0042123685 scopus 로고    scopus 로고
    • Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
    • Bø L, Vedeler CA, Nyland H, Trapp BD, Mørk SJ. Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult. Scler 2003; 9 (4): 323-331.
    • (2003) Mult. Scler , vol.9 , Issue.4 , pp. 323-331
    • Bø, L.1    Vedeler, C.A.2    Nyland, H.3    Trapp, B.D.4    Mørk, S.J.5
  • 24
    • 33846093882 scopus 로고    scopus 로고
    • Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis
    • Bö L, Geurts JJ, van der Valk P, Polman C, Barkhof F. Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis. Arch. Neurol 2007; 64 (1): 76-80.
    • (2007) Arch. Neurol , vol.64 , Issue.1 , pp. 76-80
    • Bö, L.1    Geurts, J.J.2    van der Valk, P.3    Polman, C.4    Barkhof, F.5
  • 26
    • 38849143389 scopus 로고    scopus 로고
    • Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1.J
    • Boillée S, Cleveland DW. Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1.J. Clin. Invest 2008; 118 (2): 474-478.
    • (2008) Clin. Invest , vol.118 , Issue.2 , pp. 474-478
    • Boillée, S.1    Cleveland, D.W.2
  • 27
    • 0028364696 scopus 로고
    • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
    • Boka G, Anglade P, Wallach D, Javoy-Agid F, Agid Y, Hirsch EC. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci. Lett 1994; 172 (1-2): 151-154.
    • (1994) Neurosci. Lett , vol.172 , Issue.1-2 , pp. 151-154
    • Boka, G.1    Anglade, P.2    Wallach, D.3    Javoy-Agid, F.4    Agid, Y.5    Hirsch, E.C.6
  • 30
    • 33750440804 scopus 로고    scopus 로고
    • Cognitive decline correlates with neuropathological stage in Parkinson's disease
    • Braak H, Rub U, Del Tredici K. Cognitive decline correlates with neuropathological stage in Parkinson's disease. J. Neurol. Sci. 2006; 248 (1-2): 255-258.
    • (2006) J. Neurol. Sci. , vol.248 , Issue.1-2 , pp. 255-258
    • Braak, H.1    Rub, U.2    Del Tredici, K.3
  • 31
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system.J
    • Bsibsi M, Ravid R, Gveric D, van Noort JM. Broad expression of Toll-like receptors in the human central nervous system.J. Neuropathol. Exp. Neurol. 2002; 61 (11): 1013-1021.
    • (2002) Neuropathol. Exp. Neurol. , vol.61 , Issue.11 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    van Noort, J.M.4
  • 32
    • 34447644067 scopus 로고    scopus 로고
    • Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model
    • Butovsky O, Kunis G, Koronyo-Hamaoui M, Schwartz M. Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model. Eur. J. Neurosci 2007; 26 (2): 413-416.
    • (2007) Eur. J. Neurosci , vol.26 , Issue.2 , pp. 413-416
    • Butovsky, O.1    Kunis, G.2    Koronyo-Hamaoui, M.3    Schwartz, M.4
  • 34
    • 9644254411 scopus 로고    scopus 로고
    • In vivo detection of microglial activation in frontotemporal dementia
    • Cagnin A, Rossor M, Sampson EL, Mackinnon T, Banati RB. In vivo detection of microglial activation in frontotemporal dementia. Ann. Neurol. 2004; 56 (6): 894-897.
    • (2004) Ann. Neurol. , vol.56 , Issue.6 , pp. 894-897
    • Cagnin, A.1    Rossor, M.2    Sampson, E.L.3    Mackinnon, T.4    Banati, R.B.5
  • 35
    • 33846571886 scopus 로고    scopus 로고
    • The origin and cell lineage of microglia: new concepts
    • Chan WY, Kohsaka S, Rezaie P. The origin and cell lineage of microglia: new concepts. Brain Res Rev 2007; 53 (2): 344-354.
    • (2007) Brain Res Rev , vol.53 , Issue.2 , pp. 344-354
    • Chan, W.Y.1    Kohsaka, S.2    Rezaie, P.3
  • 36
    • 58149303036 scopus 로고    scopus 로고
    • Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers
    • Chauveau F, Boutin H, Van Camp N, Dollé F, Tavitian B. Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers. Eur J Nucl Med Mol Imaging 2008; 35 (12): 2304-2319.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , Issue.12 , pp. 2304-2319
    • Chauveau, F.1    Boutin, H.2    Van Camp, N.3    Dollé, F.4    Tavitian, B.5
  • 37
    • 42649115741 scopus 로고    scopus 로고
    • Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair
    • Chen MK, Guilarte TR. Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair. Pharmacol Ther 2008; 118 (1): 1-17
    • (2008) Pharmacol Ther , vol.118 , Issue.1 , pp. 1-17
    • Chen, M.K.1    Guilarte, T.R.2
  • 38
    • 0036829178 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195
    • Choi HB, Khoo C, Ryu JK, van Breemen E, Kim SU, McLarnon JG. Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195. J. Neurochem 2002; 83 (3): 546-555.
    • (2002) J. Neurochem , vol.83 , Issue.3 , pp. 546-555
    • Choi, H.B.1    Khoo, C.2    Ryu, J.K.3    van Breemen, E.4    Kim, S.U.5    McLarnon, J.G.6
  • 39
    • 78650234355 scopus 로고    scopus 로고
    • Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state
    • Choi J, Ifuku M, Noda M, Guilarte TR. Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state. Glia. 2011; 59 (2): 219-230.
    • (2011) Glia. , vol.59 , Issue.2 , pp. 219-230
    • Choi, J.1    Ifuku, M.2    Noda, M.3    Guilarte, T.R.4
  • 40
    • 0036459335 scopus 로고    scopus 로고
    • Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging
    • Cicchetti F, Brownell AL, Williams K, Chen YI, Livni E, Isacson O. Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. Eur. J. Neurosci. 2002; 15 (6):991-998.
    • (2002) Eur. J. Neurosci. , vol.15 , Issue.6 , pp. 991-998
    • Cicchetti, F.1    Brownell, A.L.2    Williams, K.3    Chen, Y.I.4    Livni, E.5    Isacson, O.6
  • 42
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A. Multiple sclerosis. Lancet 2008; 372 (9648): 1502-1517.
    • (2008) Lancet , vol.372 , Issue.9648 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 43
    • 0034676548 scopus 로고    scopus 로고
    • Relapses and progression of disability in multiple sclerosis
    • Confavreux C, Vukusic S, Moreau T, Adeleine P. Relapses and progression of disability in multiple sclerosis. N Engl. J. Med. 2000; 343 (20): 1430-1438.
    • (2000) N Engl. J. Med. , vol.343 , Issue.20 , pp. 1430-1438
    • Confavreux, C.1    Vukusic, S.2    Moreau, T.3    Adeleine, P.4
  • 44
    • 0343924385 scopus 로고    scopus 로고
    • Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 binding in relation to imidazoline-I2-receptor and alpha 2-adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat
    • Conway EL, Gundlach AL, Craven JA. Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 binding in relation to imidazoline-I2-receptor and alpha 2-adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat. Neuroscience 1998; 82 (3): 805-817.
    • (1998) Neuroscience , vol.82 , Issue.3 , pp. 805-817
    • Conway, E.L.1    Gundlach, A.L.2    Craven, J.A.3
  • 45
    • 27344438938 scopus 로고    scopus 로고
    • Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
    • Croisier E, Moran LB, Dexter DT, Pearce RK, Graeber MB. Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition. J. Neuroinflammation 2005; 2: 14.
    • (2005) J. Neuroinflammation , vol.2 , pp. 14
    • Croisier, E.1    Moran, L.B.2    Dexter, D.T.3    Pearce, R.K.4    Graeber, M.B.5
  • 46
    • 0030175757 scopus 로고    scopus 로고
    • Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model
    • Czlonkowska A, Kohutnicka M, Kurkowska-Jastrzebska I, Czlonkowski A. Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model. Neurodegeneration 1996; 5 (2): 137-143.
    • (1996) Neurodegeneration , vol.5 , Issue.2 , pp. 137-143
    • Czlonkowska, A.1    Kohutnicka, M.2    Kurkowska-Jastrzebska, I.3    Czlonkowski, A.4
  • 49
    • 0034906715 scopus 로고    scopus 로고
    • Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p) reactive lesions
    • De Groot CJ, Bergers E, Kamphorst W, Ravid R, Polman CH, Barkhof F, van der Valk P. Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p) reactive lesions. Brain 2001;124 (Pt 8): 1635-1645.
    • (2001) Brain , vol.124 , Issue.PT 8 , pp. 1635-1645
    • De Groot, C.J.1    Bergers, E.2    Kamphorst, W.3    Ravid, R.4    Polman, C.H.5    Barkhof, F.6    van der Valk, P.7
  • 50
    • 75949102620 scopus 로고    scopus 로고
    • Chronic expression of low levels of tumor necrosis factor-alpha in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation
    • De Lella Ezcurra AL, Chertoff M, Ferrari C, Graciarena M, Pitossi F. Chronic expression of low levels of tumor necrosis factor-alpha in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation. Neurobiol. Dis. 2010; 37 (3): 630-640.
    • (2010) Neurobiol. Dis. , vol.37 , Issue.3 , pp. 630-640
    • De Lella Ezcurra, A.L.1    Chertoff, M.2    Ferrari, C.3    Graciarena, M.4    Pitossi, F.5
  • 51
    • 34248392684 scopus 로고    scopus 로고
    • Microglial activation and its implications in the brain diseases
    • Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Curr. Med. Chem. 2007; 14 (11): 1189-1197.
    • (2007) Curr. Med. Chem. , vol.14 , Issue.11 , pp. 1189-1197
    • Dheen, S.T.1    Kaur, C.2    Ling, E.A.3
  • 52
    • 0035696328 scopus 로고    scopus 로고
    • Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice
    • DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D. Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice. Neurobiol. Aging 2001; 22 (6): 1007-1012.
    • (2001) Neurobiol. Aging , vol.22 , Issue.6 , pp. 1007-1012
    • DiCarlo, G.1    Wilcock, D.2    Henderson, D.3    Gordon, M.4    Morgan, D.5
  • 56
    • 0035500386 scopus 로고    scopus 로고
    • Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
    • Elliott JL. Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis. Brain Res. Mol. Brain Res. 2001; 95 (1-2): 172-178.
    • (2001) Brain Res. Mol. Brain Res. , vol.95 , Issue.1-2 , pp. 172-178
    • Elliott, J.L.1
  • 57
    • 0024994099 scopus 로고
    • IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis
    • Engelhardt JI, Appel SH. IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch. Neurol. 1990; 47 (11): 1210-1216.
    • (1990) Arch. Neurol. , vol.47 , Issue.11 , pp. 1210-1216
    • Engelhardt, J.I.1    Appel, S.H.2
  • 58
    • 0038375640 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies
    • Etminan M, Gill S, Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies. BMJ 2003; 327 (7407): 128.
    • (2003) BMJ , vol.327 , Issue.7407 , pp. 128
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 59
    • 33748973074 scopus 로고    scopus 로고
    • Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra
    • Ferrari CC, Pott Godoy MC, Tarelli R, Chertoff M, Depino AM, Pitossi FJ. Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra. Neurobiol. Dis. 2006; 24 (1): 183-193.
    • (2006) Neurobiol. Dis. , vol.24 , Issue.1 , pp. 183-193
    • Ferrari, C.C.1    Pott Godoy, M.C.2    Tarelli, R.3    Chertoff, M.4    Depino, A.M.5    Pitossi, F.J.6
  • 60
    • 0025696092 scopus 로고
    • Naturally occurring cell death in the cerebral cortex of the rat and removal of dead cells by transitory phagocytes
    • Ferrer I, Bernet E, Soriano E, del Rio T, Fonseca M. Naturally occurring cell death in the cerebral cortex of the rat and removal of dead cells by transitory phagocytes. Neuroscience 1990; 39 (2): 451-458.
    • (1990) Neuroscience , vol.39 , Issue.2 , pp. 451-458
    • Ferrer, I.1    Bernet, E.2    Soriano, E.3    del Rio, T.4    Fonseca, M.5
  • 61
    • 0035865406 scopus 로고    scopus 로고
    • Brain dendritic cells and macrophages/microglia in central nervous system inflammation
    • Fischer HG, Reichmann G. Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J. Immunol. 2001; 166 (4): 2717-2726.
    • (2001) J. Immunol. , vol.166 , Issue.4 , pp. 2717-2726
    • Fischer, H.G.1    Reichmann, G.2
  • 62
    • 14944385354 scopus 로고    scopus 로고
    • Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors
    • Floden AM, Li S, Combs CK. Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. J. Neurosci. 2005; 25 (10): 2566-2575.
    • (2005) J. Neurosci. , vol.25 , Issue.10 , pp. 2566-2575
    • Floden, A.M.1    Li, S.2    Combs, C.K.3
  • 64
    • 38949112843 scopus 로고    scopus 로고
    • Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation
    • Fujita M, Imaizumi M, Zoghbi SS, Fujimura Y, Farris AG, Suhara T, Hong J, Pike VW, Innis RB. Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation. Neuroimage 2008; 40 (1): 43-52.
    • (2008) Neuroimage , vol.40 , Issue.1 , pp. 43-52
    • Fujita, M.1    Imaizumi, M.2    Zoghbi, S.S.3    Fujimura, Y.4    Farris, A.G.5    Suhara, T.6    Hong, J.7    Pike, V.W.8    Innis, R.B.9
  • 65
    • 0036316772 scopus 로고    scopus 로고
    • Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease
    • Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, Liu B. Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. J. Neurochem 2002; 81 (6): 1285-1297.
    • (2002) J. Neurochem , vol.81 , Issue.6 , pp. 1285-1297
    • Gao, H.M.1    Jiang, J.2    Wilson, B.3    Zhang, W.4    Hong, J.S.5    Liu, B.6
  • 69
    • 33244465587 scopus 로고    scopus 로고
    • In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy
    • Gerhard A, Trender-Gerhard I, Turkheimer F, Quinn NP, Bhatia KP, Brooks DJ. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy. Mov. Disord 2006b; 21 (1): 89-93.
    • (2006) Mov. Disord , vol.21 , Issue.1 , pp. 89-93
    • Gerhard, A.1    Trender-Gerhard, I.2    Turkheimer, F.3    Quinn, N.P.4    Bhatia, K.P.5    Brooks, D.J.6
  • 70
    • 0029076362 scopus 로고
    • Microglia: intrinsic immuneffector cell of the brain
    • Science. 2005 27; 308 (5726):1314-1318.
    • Gehrmann J, Matsumoto Y, Kreutzberg GW. Microglia: intrinsic immuneffector cell of the brain. Brain Res Brain Res Rev 1995; 20 (3): 269-287. Science. 2005 27; 308 (5726):1314-1318.
    • (1995) Brain Res Brain Res Rev , vol.20 , Issue.3 , pp. 269-287
    • Gehrmann, J.1    Matsumoto, Y.2    Kreutzberg, G.W.3
  • 71
    • 0024446372 scopus 로고
    • Corticobasal degeneration
    • Gibb WR, Luthert PJ, Marsden CD. Corticobasal degeneration. Brain. 1989; 112 (Pt 5):1171-1192.
    • (1989) Brain. , vol.112 , Issue.PT 5 , pp. 1171-1192
    • Gibb, W.R.1    Luthert, P.J.2    Marsden, C.D.3
  • 73
    • 77349114038 scopus 로고    scopus 로고
    • Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis
    • Graber DJ, Hickey WF, Harris BT. Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis. J. Neuroinflammation 2010; 7:8.
    • (2010) J. Neuroinflammation , vol.7 , pp. 8
    • Graber, D.J.1    Hickey, W.F.2    Harris, B.T.3
  • 76
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297 (5580): 353-356.
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 77
    • 0033169233 scopus 로고    scopus 로고
    • Interleukin-1beta, inducible nitric oxide synthase, and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection
    • Hartlage-Rübsamen M, Lemke R, Schliebs R. Interleukin-1beta, inducible nitric oxide synthase, and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection. J. Neurosci. Res. 1999; 57 (3): 388-398.
    • (1999) J. Neurosci. Res. , vol.57 , Issue.3 , pp. 388-398
    • Hartlage-Rübsamen, M.1    Lemke, R.2    Schliebs, R.3
  • 82
    • 70449650338 scopus 로고    scopus 로고
    • Microglia processes block the spread of damage in the brain and require functional chloride channels
    • Hines DJ, Hines RM, Mulligan SJ, Macvicar BA. Microglia processes block the spread of damage in the brain and require functional chloride channels. Glia 2009; 57 (15): 1610-1618.
    • (2009) Glia , vol.57 , Issue.15 , pp. 1610-1618
    • Hines, D.J.1    Hines, R.M.2    Mulligan, S.J.3    Macvicar, B.A.4
  • 84
    • 0842299498 scopus 로고    scopus 로고
    • Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys
    • Hurley SD, O'Banion MK, Song DD, Arana FS, Olschowka JA, Haber SN. Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys. Exp. Neurol. 2003; 184 (2): 659-668.
    • (2003) Exp. Neurol. , vol.184 , Issue.2 , pp. 659-668
    • Hurley, S.D.1    O'Banion, M.K.2    Song, D.D.3    Arana, F.S.4    Olschowka, J.A.5    Haber, S.N.6
  • 87
    • 0344444234 scopus 로고    scopus 로고
    • Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains
    • Imamura K, Hishikawa N, Sawada M, Nagatsu T, Yoshida M, Hashizume Y. Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains. Acta Neuropathol. 2003; 106 (6): 518-526.
    • (2003) Acta Neuropathol. , vol.106 , Issue.6 , pp. 518-526
    • Imamura, K.1    Hishikawa, N.2    Sawada, M.3    Nagatsu, T.4    Yoshida, M.5    Hashizume, Y.6
  • 89
    • 0034996076 scopus 로고    scopus 로고
    • Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration
    • Ishizawa K, Dickson DW. Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration. J. Neuropathol. Exp. Neurol. 2001; 60 (6): 647-657.
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , Issue.6 , pp. 647-657
    • Ishizawa, K.1    Dickson, D.W.2
  • 91
    • 0026605961 scopus 로고
    • Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
    • Kawamata T, Akiyama H, Yamada T, McGeer PL. Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am. J. Pathol. 1992; 140 (3): 691-707.
    • (1992) Am. J. Pathol. , vol.140 , Issue.3 , pp. 691-707
    • Kawamata, T.1    Akiyama, H.2    Yamada, T.3    McGeer, P.L.4
  • 92
    • 0025287977 scopus 로고
    • The pathogenesis of multiple sclerosis
    • Kesselring J. The pathogenesis of multiple sclerosis. Schweiz Med. Wochenschr 1990; 120 (30): 1083-1090.
    • (1990) Schweiz Med. Wochenschr , vol.120 , Issue.30 , pp. 1083-1090
    • Kesselring, J.1
  • 93
    • 0026526693 scopus 로고
    • Immunohistochemical study of a case with progressive supranuclear palsy without ophthalmoplegia
    • Kida E, Barcikowska M, Niemczewska M. Immunohistochemical study of a case with progressive supranuclear palsy without ophthalmoplegia. Acta Neuropathol. 1992; 83 (3):328-332.
    • (1992) Acta Neuropathol. , vol.83 , Issue.3 , pp. 328-332
    • Kida, E.1    Barcikowska, M.2    Niemczewska, M.3
  • 94
    • 70349334516 scopus 로고    scopus 로고
    • Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease
    • Kim S, Moon M, Park S. Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease. J. Endocrinol. 2009; 202 (3): 431-439.
    • (2009) J. Endocrinol. , vol.202 , Issue.3 , pp. 431-439
    • Kim, S.1    Moon, M.2    Park, S.3
  • 95
    • 24744467358 scopus 로고    scopus 로고
    • Microglial phagocytosis induced by fibrillar betaamyloid and IgGs are differentially regulated by proinflammatory cytokines
    • Koenigsknecht-Talboo J, Landreth GE. Microglial phagocytosis induced by fibrillar betaamyloid and IgGs are differentially regulated by proinflammatory cytokines. J. Neurosci. 2005; 25 (36): 8240-8249.
    • (2005) J. Neurosci. , vol.25 , Issue.36 , pp. 8240-8249
    • Koenigsknecht-Talboo, J.1    Landreth, G.E.2
  • 96
    • 0034237154 scopus 로고    scopus 로고
    • Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis
    • Kohji T, Matsumoto Y. Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis. J. Neuroimmunol 2000; 106 (1-2): 165-171.
    • (2000) J. Neuroimmunol , vol.106 , Issue.1-2 , pp. 165-171
    • Kohji, T.1    Matsumoto, Y.2
  • 97
    • 0031952714 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS)-like immunoreactivity in argyrophilic, tau-positive astrocytes in progressive supranuclear palsy
    • Komori T, Shibata N, Kobayashi M, Sasaki S, Iwata M. Inducible nitric oxide synthase (iNOS)-like immunoreactivity in argyrophilic, tau-positive astrocytes in progressive supranuclear palsy. Acta Neuropathol. 1998; 95 (4): 338-344.
    • (1998) Acta Neuropathol. , vol.95 , Issue.4 , pp. 338-344
    • Komori, T.1    Shibata, N.2    Kobayashi, M.3    Sasaki, S.4    Iwata, M.5
  • 98
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci.1996; 19: 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 99
    • 0026646024 scopus 로고
    • Amyotrophic lateral sclerosis: interleukin-6 levels in cerebrospinal fluid
    • Krieger C, Perry TL, Ziltener HJ. Amyotrophic lateral sclerosis: interleukin-6 levels in cerebrospinal fluid. Can. J. Neurol. Sci. 1992; 19 (3): 357-359.
    • (1992) Can. J. Neurol. Sci. , vol.19 , Issue.3 , pp. 357-359
    • Krieger, C.1    Perry, T.L.2    Ziltener, H.J.3
  • 102
    • 0033514002 scopus 로고    scopus 로고
    • Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis
    • Lacor P, Gandolfo P, Tonon MC, Brault E, Dalibert I, Schumacher M, Benavides J, Ferzaz B. Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis. Brain Res. 1999; 815 (1): 70-80.
    • (1999) Brain Res. , vol.815 , Issue.1 , pp. 70-80
    • Lacor, P.1    Gandolfo, P.2    Tonon, M.C.3    Brault, E.4    Dalibert, I.5    Schumacher, M.6    Benavides, J.7    Ferzaz, B.8
  • 103
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine exposure
    • Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine exposure. Ann. Neurol. 1999; 46 (4): 598-605.
    • (1999) Ann. Neurol. , vol.46 , Issue.4 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 104
    • 0028087201 scopus 로고
    • Cellular pathology of multiple system atrophy: a review
    • Lantos PL, Papp MI. Cellular pathology of multiple system atrophy: a review. J. Neurol. Neurosurg Psychiatry 1994; 57 (2): 129-133.
    • (1994) J. Neurol. Neurosurg Psychiatry , vol.57 , Issue.2 , pp. 129-133
    • Lantos, P.L.1    Papp, M.I.2
  • 105
    • 53049085062 scopus 로고    scopus 로고
    • Mechanisms of inflammation induced tissue injury in multiple sclerosis
    • Lassmann H. Mechanisms of inflammation induced tissue injury in multiple sclerosis. J. Neurol. Sci. 2008; 274 (1-2): 45-47.
    • (2008) J. Neurol. Sci. , vol.274 , Issue.1-2 , pp. 45-47
    • Lassmann, H.1
  • 106
    • 0025220976 scopus 로고
    • Heterogeniety in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson LJ, Perry VH, Dri P, Gordon S. Heterogeniety in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 1990; 39: 151-170.
    • (1990) Neuroscience , vol.39 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 108
    • 79952897537 scopus 로고    scopus 로고
    • Microglia activation mediates fibrillar amyloid-ß toxicity in the aged primate cortex
    • Leung E, Guo L, Bu J, Maloof M, El Khoury J, Geula C. Microglia activation mediates fibrillar amyloid-ß toxicity in the aged primate cortex. Neurobiol. Aging 2011; 32 (3):387-397.
    • (2011) Neurobiol. Aging , vol.32 , Issue.3 , pp. 387-397
    • Leung, E.1    Guo, L.2    Bu, J.3    Maloof, M.4    El Khoury, J.5    Geula, C.6
  • 109
    • 10344230955 scopus 로고    scopus 로고
    • Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a nonimmune model of demyelination
    • Li WW, Setzu A, Zhao C, Franklin RJ. Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a nonimmune model of demyelination. J. Neuroimmunol. 2005; 158 (1-2): 58-66.
    • (2005) J. Neuroimmunol. , vol.158 , Issue.1-2 , pp. 58-66
    • Li, W.W.1    Setzu, A.2    Zhao, C.3    Franklin, R.J.4
  • 110
    • 0029948229 scopus 로고    scopus 로고
    • Microglia-derived macrophages in early multiple sclerosis plaques
    • Li H, Cuzner ML, Newcombe J. Microglia-derived macrophages in early multiple sclerosis plaques. Neuropathol Appl. Neurobiol. 1996; 22 (3): 207-215.
    • (1996) Neuropathol Appl. Neurobiol. , vol.22 , Issue.3 , pp. 207-215
    • Li, H.1    Cuzner, M.L.2    Newcombe, J.3
  • 111
    • 34447332831 scopus 로고    scopus 로고
    • The function of microglia, either neuroprotection or neurotoxicity, is determined by the equilibrium among factors released from activated microglia in vitro
    • Li L, Lu J, Tay SS, Moochhala SM, He BP. The function of microglia, either neuroprotection or neurotoxicity, is determined by the equilibrium among factors released from activated microglia in vitro. Brain Res. 2007; 1159: 8-17.
    • (2007) Brain Res. , vol.1159 , pp. 8-17
    • Li, L.1    Lu, J.2    Tay, S.S.3    Moochhala, S.M.4    He, B.P.5
  • 112
    • 0037096354 scopus 로고    scopus 로고
    • Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
    • Lino MM, Schneider C, Caroni P. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J. Neurosci. 2002; 22 (12):4825-4832.
    • (2002) J. Neurosci. , vol.22 , Issue.12 , pp. 4825-4832
    • Lino, M.M.1    Schneider, C.2    Caroni, P.3
  • 113
    • 63649152262 scopus 로고    scopus 로고
    • Expression of amyotrophic lateral sclerosislinked SOD1 mutant increases the neurotoxic potential of microglia via TLR2
    • Liu Y, Hao W, Dawson A, Liu S, Fassbender K. Expression of amyotrophic lateral sclerosislinked SOD1 mutant increases the neurotoxic potential of microglia via TLR2. J. Biol. Chem. 2009; 284 (6): 3691-3699.
    • (2009) J. Biol. Chem. , vol.284 , Issue.6 , pp. 3691-3699
    • Liu, Y.1    Hao, W.2    Dawson, A.3    Liu, S.4    Fassbender, K.5
  • 114
    • 55349135951 scopus 로고    scopus 로고
    • Novel therapeutic strategies for multiple sclerosis--a multifaceted adversary
    • Lopez-Diego RS, Weiner HL. Novel therapeutic strategies for multiple sclerosis--a multifaceted adversary. Nat. Rev. Drug Discov. 2008; 7 (11): 909-925.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.11 , pp. 909-925
    • Lopez-Diego, R.S.1    Weiner, H.L.2
  • 115
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M, Reynolds R, Aloisi F. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007; 130 (Pt 4): 1089-1104.
    • (2007) Brain , vol.130 , Issue.PT 4 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3    Serafini, B.4    Nicholas, R.5    Puopolo, M.6    Reynolds, R.7    Aloisi, F.8
  • 118
    • 0034931018 scopus 로고    scopus 로고
    • Diazepam stimulates migration and phagocytosis of human neutrophils: possible contribution of peripheral-type benzodiazepine receptors and intracellular calcium
    • Marino F, Cattaneo S, Cosentino M, Rasini E, Di Grazia L, Fietta AM, Lecchini S, Frigo G. Diazepam stimulates migration and phagocytosis of human neutrophils: possible contribution of peripheral-type benzodiazepine receptors and intracellular calcium. Pharmacology 2001; 63 (1): 42-49.
    • (2001) Pharmacology , vol.63 , Issue.1 , pp. 42-49
    • Marino, F.1    Cattaneo, S.2    Cosentino, M.3    Rasini, E.4    Di Grazia, L.5    Fietta, A.M.6    Lecchini, S.7    Frigo, G.8
  • 119
    • 0034097279 scopus 로고    scopus 로고
    • Local neurochemicals and site specific immune regulation in the CNS.J
    • McCluskey LP, Lampson LA. Local neurochemicals and site specific immune regulation in the CNS.J. Neuropathol. Exp. Neurol. 2000; 59: 177-187.
    • (2000) Neuropathol. Exp. Neurol. , vol.59 , pp. 177-187
    • McCluskey, L.P.1    Lampson, L.A.2
  • 120
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988a; 38: 1285-1291.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 121
    • 0023782375 scopus 로고
    • Expression of the histocompatibility glycoprotein HLADR in neurological disease
    • McGeer PL, Itagaki S, McGeer EG. Expression of the histocompatibility glycoprotein HLADR in neurological disease. Acta Neuropathol 1988b; 76 (6): 550-557.
    • (1988) Acta Neuropathol , vol.76 , Issue.6 , pp. 550-557
    • McGeer, P.L.1    Itagaki, S.2    McGeer, E.G.3
  • 122
    • 0242549003 scopus 로고    scopus 로고
    • Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
    • McKercher SR, Torbett BE, Anderson KL, Henkel GW, Vestal DJ, et al. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 1996; 15:5647-5658.
    • (1996) EMBO J. , vol.15 , pp. 5647-5658
    • McKercher, S.R.1    Torbett, B.E.2    Anderson, K.L.3    Henkel, G.W.4    Vestal, D.J.5
  • 123
    • 0344110538 scopus 로고    scopus 로고
    • Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease
    • Messmer K, Reynolds GP. Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease. Neurosci. Lett 1998; 241(1): 53-56.
    • (1998) Neurosci. Lett , vol.241 , Issue.1 , pp. 53-56
    • Messmer, K.1    Reynolds, G.P.2
  • 124
    • 67349251479 scopus 로고    scopus 로고
    • Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions:Effects of oligomeric and fibrillar amyloid-beta
    • Michelucci A, Heurtaux T, Grandbarbe L, Morga E, Heuschling P. Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions:Effects of oligomeric and fibrillar amyloid-beta. J. Neuroimmunol. 2009; 210 (1-2): 3-12.
    • (2009) J. Neuroimmunol. , vol.210 , Issue.1-2 , pp. 3-12
    • Michelucci, A.1    Heurtaux, T.2    Grandbarbe, L.3    Morga, E.4    Heuschling, P.5
  • 125
    • 0345856174 scopus 로고    scopus 로고
    • Aging and dementia
    • In: Graham DI, Lantos PL, eds., London: Arnold
    • Mirra SS, Hyman BT. Aging and dementia. In: Graham DI, Lantos PL, eds. Greenfield's neuropathology. Vol 2. London: Arnold, 2002: 195-271.
    • (2002) Greenfield's neuropathology. , vol.2 , pp. 195-271
    • Mirra, S.S.1    Hyman, B.T.2
  • 126
    • 0028178281 scopus 로고
    • Tumor necrosis factoralpha (TNF- alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients
    • Mogi M, Harada M, Riederer P, Narabayashi H, Fujita K, Nagatsu T. Tumor necrosis factoralpha (TNF- alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci. Lett 1994; 165: 208-210.
    • (1994) Neurosci. Lett , vol.165 , pp. 208-210
    • Mogi, M.1    Harada, M.2    Riederer, P.3    Narabayashi, H.4    Fujita, K.5    Nagatsu, T.6
  • 127
    • 0038270736 scopus 로고    scopus 로고
    • The neuropathology and biochemistry of frontotemporal dementia
    • Munoz DG, Dickson DW, Bergeron, eds. The neuropathology and biochemistry of frontotemporal dementia. Ann. Neurol. 2003; 54 (Suppl 15): 24-28.
    • (2003) Ann. Neurol. , vol.54 , Issue.SUPPL. 15 , pp. 24-28
    • Munoz, D.G.1    Dickson, D.W.2    Bergeron3
  • 128
    • 59349112140 scopus 로고    scopus 로고
    • Microglial clearance function in health and disease
    • Napoli I, Neumann H. Microglial clearance function in health and disease. Neuroscience 2009; 158 (3): 1030-1038.
    • (2009) Neuroscience , vol.158 , Issue.3 , pp. 1030-1038
    • Napoli, I.1    Neumann, H.2
  • 131
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005; 308 (5726): 1314-1318.
    • (2005) Science , vol.308 , Issue.5726 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 140
    • 0035157681 scopus 로고    scopus 로고
    • Apoptosis of inflammatory cells in immune control of the nervous system: role of glia
    • Pender MP, Rist MJ. Apoptosis of inflammatory cells in immune control of the nervous system: role of glia. Glia 2001; 36 (2): 137-144.
    • (2001) Glia , vol.36 , Issue.2 , pp. 137-144
    • Pender, M.P.1    Rist, M.J.2
  • 141
    • 0027331779 scopus 로고
    • Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease
    • Peress NS, Fleit HB, Perillo E, Kuljis R, Pezzullo C. Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease. J. Neuroimmunol. 1993; 48 (1):71-79.
    • (1993) J. Neuroimmunol. , vol.48 , Issue.1 , pp. 71-79
    • Peress, N.S.1    Fleit, H.B.2    Perillo, E.3    Kuljis, R.4    Pezzullo, C.5
  • 142
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • Peterson JW, Bö L, Mörk S, Chang A, Trapp BD. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol. 2001; 50 (3):389-400.
    • (2001) Ann Neurol. , vol.50 , Issue.3 , pp. 389-400
    • Peterson, J.W.1    Bö, L.2    Mörk, S.3    Chang, A.4    Trapp, B.D.5
  • 144
    • 0027238911 scopus 로고
    • Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status
    • Pike VW, Halldin C, Crouzel C, Barré L, Nutt DJ, Osman S, Shah F, Turton DR, Waters SL. Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status. Nucl. Med. Biol. 1993;20 (4): 503-525.
    • (1993) Nucl. Med. Biol. , vol.20 , Issue.4 , pp. 503-525
    • Pike, V.W.1    Halldin, C.2    Crouzel, C.3    Barré, L.4    Nutt, D.J.5    Osman, S.6    Shah, F.7    Turton, D.R.8    Waters, S.L.9
  • 145
    • 55749087155 scopus 로고    scopus 로고
    • Hypothalamic involvement in Huntington's disease: an in vivo PET study
    • Politis M, Pavese N, Tai YF, Tabrizi SJ, Barker RA, Piccini P. Hypothalamic involvement in Huntington's disease: an in vivo PET study. Brain 2008; 131 (Pt 11): 2860-2869.
    • (2008) Brain , vol.131 , Issue.PT 11 , pp. 2860-2869
    • Politis, M.1    Pavese, N.2    Tai, Y.F.3    Tabrizi, S.J.4    Barker, R.A.5    Piccini, P.6
  • 146
    • 78651422988 scopus 로고    scopus 로고
    • Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study
    • Politis M, Pavese N, Tai YF, Kiferle L, Mason SL, Brooks DJ, Tabrizi SJ, Barker RA, Piccini P. Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study. Hum. Brain Mapp 2011; 32 (2): 258-270.
    • (2011) Hum. Brain Mapp , vol.32 , Issue.2 , pp. 258-270
    • Politis, M.1    Pavese, N.2    Tai, Y.F.3    Kiferle, L.4    Mason, S.L.5    Brooks, D.J.6    Tabrizi, S.J.7    Barker, R.A.8    Piccini, P.9
  • 148
    • 0034733968 scopus 로고    scopus 로고
    • Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
    • Poloni M, Facchetti D, Mai R, Micheli A, Agnoletti L, Francolini G, Mora G, Camana C, Mazzini L, Bachetti T. Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis. Neurosci. Lett 2000; 287 (3): 211-214.
    • (2000) Neurosci. Lett , vol.287 , Issue.3 , pp. 211-214
    • Poloni, M.1    Facchetti, D.2    Mai, R.3    Micheli, A.4    Agnoletti, L.5    Francolini, G.6    Mora, G.7    Camana, C.8    Mazzini, L.9    Bachetti, T.10
  • 149
    • 57049169723 scopus 로고    scopus 로고
    • Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies
    • Power JH, Blumbergs PC. Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies. Acta Neuropathol. 2009; 117 (1): 63-73.
    • (2009) Acta Neuropathol. , vol.117 , Issue.1 , pp. 63-73
    • Power, J.H.1    Blumbergs, P.C.2
  • 150
    • 0035873076 scopus 로고    scopus 로고
    • Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
    • Pramatarova A, Laganière J, Roussel J, Brisebois K, Rouleau GA. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Neurosci.2001; 21 (10): 3369-3374.
    • (2001) J. Neurosci. , vol.21 , Issue.10 , pp. 3369-3374
    • Pramatarova, A.1    Laganière, J.2    Roussel, J.3    Brisebois, K.4    Rouleau, G.A.5
  • 151
    • 0028304387 scopus 로고
    • Multiple sclerosis: immune system molecule ex- pression in the central nervous system
    • Raine CS. Multiple sclerosis: immune system molecule ex- pression in the central nervous system. J. Neuropathol. Exp. Neurol. 1994; 53: 328-337.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 328-337
    • Raine, C.S.1
  • 152
    • 9644310402 scopus 로고    scopus 로고
    • Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease
    • Raivich G, Banati R. Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease. Brain Res. Brain Res. Rev. 2004; 46 (3): 261-281.
    • (2004) Brain Res. Brain Res. Rev. , vol.46 , Issue.3 , pp. 261-281
    • Raivich, G.1    Banati, R.2
  • 153
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: unique stimuli, specialized responses
    • Ransohoff RM, Perry VH. Microglial physiology: unique stimuli, specialized responses. Annu. Rev. Immunol.2009; 27: 119-145.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 154
    • 0029009234 scopus 로고
    • Neuropsychology of multiple sclerosis
    • Rao SM. Neuropsychology of multiple sclerosis. Curr. Opin. Neurol. 1995; 8 (3): 216-220.
    • (1995) Curr. Opin. Neurol. , vol.8 , Issue.3 , pp. 216-220
    • Rao, S.M.1
  • 155
    • 35649010838 scopus 로고    scopus 로고
    • Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis
    • Rasmussen S, Wang Y, Kivisäkk P, Bronson RT, Meyer M, Imitola J, Khoury SJ. Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis. Brain 2007; 130 (Pt 11): 2816-2829.
    • (2007) Brain , vol.130 , Issue.PT 11 , pp. 2816-2829
    • Rasmussen, S.1    Wang, Y.2    Kivisäkk, P.3    Bronson, R.T.4    Meyer, M.5    Imitola, J.6    Khoury, S.J.7
  • 156
    • 0014225976 scopus 로고
    • Corticodentatonigral degeneration with neuronal achromasia
    • Rebeiz JJ, Kolodny EH, Richardson EP Jr. Corticodentatonigral degeneration with neuronal achromasia. Arch. Neurol. 1968; 18 (1): 20-33.
    • (1968) Arch. Neurol. , vol.18 , Issue.1 , pp. 20-33
    • Rebeiz, J.J.1    Kolodny, E.H.2    Richardson Jr, E.P..3
  • 158
    • 77955506963 scopus 로고    scopus 로고
    • Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis
    • Sanagi T, Yuasa S, Nakamura Y, Suzuki E, Aoki M, Warita H, Itoyama Y, Uchino S, Kohsaka S, Ohsawa K. Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis. J. Neurosci. Res. 2010; 88 (12): 2736-2746.
    • (2010) J. Neurosci. Res. , vol.88 , Issue.12 , pp. 2736-2746
    • Sanagi, T.1    Yuasa, S.2    Nakamura, Y.3    Suzuki, E.4    Aoki, M.5    Warita, H.6    Itoyama, Y.7    Uchino, S.8    Kohsaka, S.9    Ohsawa, K.10
  • 159
    • 77649294300 scopus 로고    scopus 로고
    • Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease
    • Sanchez-Guajardo V, Febbraro F, Kirik D, Romero-Ramos M. Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease. PLoS One. 2010; 5 (1).
    • (2010) PLoS One. , vol.5 , Issue.1
    • Sanchez-Guajardo, V.1    Febbraro, F.2    Kirik, D.3    Romero-Ramos, M.4
  • 161
    • 74049122793 scopus 로고    scopus 로고
    • Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1
    • Sargsyan SA, Blackburn DJ, Barber SC, Monk PN, Shaw PJ. Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1. Neuroreport 2009; 20 (16): 1450-1455.
    • (2009) Neuroreport , vol.20 , Issue.16 , pp. 1450-1455
    • Sargsyan, S.A.1    Blackburn, D.J.2    Barber, S.C.3    Monk, P.N.4    Shaw, P.J.5
  • 162
    • 61449203017 scopus 로고    scopus 로고
    • The translocator protein (18 kDa): central nervous system disease and drug design
    • Scarf AM, Ittner LM, Kassiou M. The translocator protein (18 kDa): central nervous system disease and drug design. J. Med. Chem. 2009; 52 (3): 581-592.
    • (2009) J. Med. Chem. , vol.52 , Issue.3 , pp. 581-592
    • Scarf, A.M.1    Ittner, L.M.2    Kassiou, M.3
  • 163
    • 0042190147 scopus 로고    scopus 로고
    • Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice
    • Schilling M, Besselmann M, Leonhard C, Mueller M, Ringelstein EB, Kiefer R. Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice. Exp. Neurol. 2003; 183 (1): 25-33.
    • (2003) Exp. Neurol. , vol.183 , Issue.1 , pp. 25-33
    • Schilling, M.1    Besselmann, M.2    Leonhard, C.3    Mueller, M.4    Ringelstein, E.B.5    Kiefer, R.6
  • 165
    • 0032485033 scopus 로고    scopus 로고
    • Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases
    • Sekizawa T, Openshaw H, Ohbo K, Sugamura K, Itoyama Y, Niland JC. Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases. J. Neurol. Sci. 1998; 154 (2): 194-199.
    • (1998) J. Neurol. Sci. , vol.154 , Issue.2 , pp. 194-199
    • Sekizawa, T.1    Openshaw, H.2    Ohbo, K.3    Sugamura, K.4    Itoyama, Y.5    Niland, J.C.6
  • 167
    • 0035955478 scopus 로고    scopus 로고
    • Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
    • Shibata N, Nagai R, Uchida K, Horiuchi S, Yamada S, Hirano A, Kawaguchi M, Yamamoto T, Sasaki S, Kobayashi M. Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 2001; 917 (1): 97-104.
    • (2001) Brain Res , vol.917 , Issue.1 , pp. 97-104
    • Shibata, N.1    Nagai, R.2    Uchida, K.3    Horiuchi, S.4    Yamada, S.5    Hirano, A.6    Kawaguchi, M.7    Yamamoto, T.8    Sasaki, S.9    Kobayashi, M.10
  • 168
    • 0032873347 scopus 로고    scopus 로고
    • Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease
    • Singhrao SK, Neal JW, Morgan BP, Gasque P. Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease. Exp. Neurol. 1999; 159 (2): 362-376.
    • (1999) Exp. Neurol. , vol.159 , Issue.2 , pp. 362-376
    • Singhrao, S.K.1    Neal, J.W.2    Morgan, B.P.3    Gasque, P.4
  • 169
    • 0035144689 scopus 로고    scopus 로고
    • Autoradiography with [3H]PK11195 of spinal tract degeneration in amyotrophic lateral sclerosis
    • Sitte HH, Wanschitz J, Budka H, Berger ML. Autoradiography with [3H]PK11195 of spinal tract degeneration in amyotrophic lateral sclerosis. Acta Neuropathol. 2001; 101 (2): 75-78.
    • (2001) Acta Neuropathol. , vol.101 , Issue.2 , pp. 75-78
    • Sitte, H.H.1    Wanschitz, J.2    Budka, H.3    Berger, M.L.4
  • 170
    • 0033062691 scopus 로고    scopus 로고
    • CD28/ CTLA-4 and CD80/ CD86 families: signaling and function
    • Slavik JM, Hutchcroft JE, Bierer BE. CD28/ CTLA-4 and CD80/ CD86 families: signaling and function. Immunol. Res. 1999; 19: 1-24.
    • (1999) Immunol. Res. , vol.19 , pp. 1-24
    • Slavik, J.M.1    Hutchcroft, J.E.2    Bierer, B.E.3
  • 171
    • 0036154041 scopus 로고    scopus 로고
    • BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?
    • Stadelmann C, Kerschensteiner M, Misgeld T, Brück W, Hohlfeld R, Lassmann H. BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain 2002; 125 (Pt 1): 75-85.
    • (2002) Brain , vol.125 , Issue.PT 1 , pp. 75-85
    • Stadelmann, C.1    Kerschensteiner, M.2    Misgeld, T.3    Brück, W.4    Hohlfeld, R.5    Lassmann, H.6
  • 172
    • 0032983536 scopus 로고    scopus 로고
    • Association of microglia with amyloid plaques in brains of APP23 transgenic mice
    • Stalder M, Phinney A, Probst A, Sommer B, Staufenbiel M, Jucker M. Association of microglia with amyloid plaques in brains of APP23 transgenic mice. Am. J. Pathol. 1999; 154 (6): 1673-1684.
    • (1999) Am. J. Pathol. , vol.154 , Issue.6 , pp. 1673-1684
    • Stalder, M.1    Phinney, A.2    Probst, A.3    Sommer, B.4    Staufenbiel, M.5    Jucker, M.6
  • 173
    • 36949032824 scopus 로고    scopus 로고
    • Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy:implications for multiple system atrophy
    • Stefanova N, Reindl M, Neumann M, Kahle PJ, Poewe W, Wenning GK. Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy:implications for multiple system atrophy. Mov. Disord. 2007; 22 (15): 2196-2203.
    • (2007) Mov. Disord. , vol.22 , Issue.15 , pp. 2196-2203
    • Stefanova, N.1    Reindl, M.2    Neumann, M.3    Kahle, P.J.4    Poewe, W.5    Wenning, G.K.6
  • 174
    • 0029047144 scopus 로고
    • Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat
    • Stephenson DT, Schober DA, Smalstig EB, Mincy RE, Gehlert DR, Clemens JA. Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat. J. Neurosci. 1995; 15 (7 Pt 2): 5263-5274.
    • (1995) J. Neurosci. , vol.15 , Issue.7 PT 2 , pp. 5263-5274
    • Stephenson, D.T.1    Schober, D.A.2    Smalstig, E.B.3    Mincy, R.E.4    Gehlert, D.R.5    Clemens, J.A.6
  • 175
    • 68249145501 scopus 로고    scopus 로고
    • Innate and adaptive immunity for the pathobiology of Parkinson's disease
    • Stone DK, Reynolds AD, Mosley RL, Gendelman HE. Innate and adaptive immunity for the pathobiology of Parkinson's disease. Antioxid Redox Signal. 2009; 11 (9): 2151-2166.
    • (2009) Antioxid Redox Signal. , vol.11 , Issue.9 , pp. 2151-2166
    • Stone, D.K.1    Reynolds, A.D.2    Mosley, R.L.3    Gendelman, H.E.4
  • 176
    • 0029981358 scopus 로고    scopus 로고
    • Selective induction of interleukin-6 in mouse microglia by granulocyte-macrophage colony-stimulating factor
    • Suzumura A, Sawada M, Marunouchi T. Selective induction of interleukin-6 in mouse microglia by granulocyte-macrophage colony-stimulating factor. Brain Res. 1996; 713 (1-2): 192-198.
    • (1996) Brain Res. , vol.713 , Issue.1-2 , pp. 192-198
    • Suzumura, A.1    Sawada, M.2    Marunouchi, T.3
  • 179
    • 0030916019 scopus 로고    scopus 로고
    • Induction of macrophage inflammatory protein MIP-1alpha mRNA on glial cells after focal cerebral ischemia in the rat
    • Takami S, Nishikawa H, Minami M, Nishiyori A, Sato M, Akaike A, Satoh M. Induction of macrophage inflammatory protein MIP-1alpha mRNA on glial cells after focal cerebral ischemia in the rat. Neurosci. Lett 1997; 227 (3): 173-176.
    • (1997) Neurosci. Lett , vol.227 , Issue.3 , pp. 173-176
    • Takami, S.1    Nishikawa, H.2    Minami, M.3    Nishiyori, A.4    Sato, M.5    Akaike, A.6    Satoh, M.7
  • 180
    • 1842471942 scopus 로고    scopus 로고
    • Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
    • Turner MR, Cagnin A, Turkheimer FE, Miller CC, Shaw CE, Brooks DJ, Leigh PN, Banati RB. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol. Dis. 2004; 15 (3): 601-609.
    • (2004) Neurobiol. Dis. , vol.15 , Issue.3 , pp. 601-609
    • Turner, M.R.1    Cagnin, A.2    Turkheimer, F.E.3    Miller, C.C.4    Shaw, C.E.5    Brooks, D.J.6    Leigh, P.N.7    Banati, R.B.8
  • 184
    • 36549056962 scopus 로고    scopus 로고
    • Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients
    • Vas A, Shchukin Y, Karrenbauer VD, Cselényi Z, Kostulas K, Hillert J, Savic I, Takano A, Halldin C, Gulyás B. Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients. J. Neurol. Sci. 2008; 264 (1-2): 9-17.
    • (2008) J. Neurol. Sci. , vol.264 , Issue.1-2 , pp. 9-17
    • Vas, A.1    Shchukin, Y.2    Karrenbauer, V.D.3    Cselényi, Z.4    Kostulas, K.5    Hillert, J.6    Savic, I.7    Takano, A.8    Halldin, C.9    Gulyás, B.10
  • 185
    • 34548238745 scopus 로고    scopus 로고
    • Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response
    • Veenman L, Papadopoulos V, Gavish M. Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response. Curr. Pharm Des. 2007; 13 (23): 2385-2405.
    • (2007) Curr. Pharm Des. , vol.13 , Issue.23 , pp. 2385-2405
    • Veenman, L.1    Papadopoulos, V.2    Gavish, M.3
  • 187
    • 43149102747 scopus 로고    scopus 로고
    • Protective effects of NSAIDs on the development of Alzheimer disease
    • Vlad SC, Miller DR, Kowall NW, Felson DT. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology 2008; 70 (19): 1672-1677.
    • (2008) Neurology , vol.70 , Issue.19 , pp. 1672-1677
    • Vlad, S.C.1    Miller, D.R.2    Kowall, N.W.3    Felson, D.T.4
  • 189
    • 0030781925 scopus 로고    scopus 로고
    • PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Vowinckel E, Reutens D, Becher B, Verge G, Evans A, Owens T, Antel JP. PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis. J. Neurosci. Res. 1997; 50 (2): 345-353.
    • (1997) J. Neurosci. Res. , vol.50 , Issue.2 , pp. 345-353
    • Vowinckel, E.1    Reutens, D.2    Becher, B.3    Verge, G.4    Evans, A.5    Owens, T.6    Antel, J.P.7
  • 190
    • 65249157852 scopus 로고    scopus 로고
    • Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
    • Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J. Neurosci. 1; 29 (13): 3974-3980.
    • J. Neurosci. , vol.1-29 , Issue.13 , pp. 3974-3980
    • Wake, H.1    Moorhouse, A.J.2    Jinno, S.3    Kohsaka, S.4    Nabekura, J.5
  • 191
    • 34748896047 scopus 로고    scopus 로고
    • NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? Trends Pharmacol
    • Weggen S, Rogers M, Eriksen J. NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? Trends Pharmacol. Sci. 2007; 28 (10): 536-543.
    • (2007) Sci. , vol.28 , Issue.10 , pp. 536-543
    • Weggen, S.1    Rogers, M.2    Eriksen, J.3
  • 192
    • 9144230806 scopus 로고    scopus 로고
    • Increased cytotoxic potential of microglia from ALS-transgenic mice
    • Weydt P, Yuen EC, Ransom BR, Möller T. Increased cytotoxic potential of microglia from ALS-transgenic mice. Glia 2004; 48 (2): 179-182.
    • (2004) Glia , vol.48 , Issue.2 , pp. 179-182
    • Weydt, P.1    Yuen, E.C.2    Ransom, B.R.3    Möller, T.4
  • 193
    • 0348109489 scopus 로고    scopus 로고
    • Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro
    • Wilms H, Claasen J, Röhl C, Sievers J, Deuschl G, Lucius R. Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro. Neurobiol. Dis. 2003; 14 (3): 417-424.
    • (2003) Neurobiol. Dis. , vol.14 , Issue.3 , pp. 417-424
    • Wilms, H.1    Claasen, J.2    Röhl, C.3    Sievers, J.4    Deuschl, G.5    Lucius, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.