β-Amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors

Journal of Neuroscience

Volumn 25, Issue 10, 2005, Pages 2566-2575

  Floden, Angela M ^a   Li, Shanshan ^a   Combs, Colin K ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Alzheimer; Amyloid; Cytokine; Glutamate; Inflammation; iNOS; Microglia; Neuron death; NMDA; TNF

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; AMYLOID BETA PROTEIN; GLUTAMIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; MICROGLIA; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN; ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; GLUTAMIC ACID; HUMANS; MICE; MICE, INBRED C57BL; MICROGLIA; NEURONS; PREGNANCY; RECEPTORS, N-METHYL-D-ASPARTATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 14944385354     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4998-04.2005     Document Type: Article

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