메뉴 건너뛰기




Volumn 159, Issue 2, 1999, Pages 362-376

Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERIN; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C9; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN; MYELIN;

EID: 0032873347     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7170     Document Type: Article
Times cited : (277)

References (54)
  • 1
    • 0022490331 scopus 로고
    • Monoclonal antibodies raised against a subsequence of cerebrovascular amyloid in Alzheimer's disease
    • Allsop D., Landon M., Kidd M., Lowe J. S., Reynolds G. P., Gardner A. Monoclonal antibodies raised against a subsequence of cerebrovascular amyloid in Alzheimer's disease. Neurosci. Lett. 68:1986;252-256.
    • (1986) Neurosci. Lett. , vol.68 , pp. 252-256
    • Allsop, D.1    Landon, M.2    Kidd, M.3    Lowe, J.S.4    Reynolds, G.P.5    Gardner, A.6
  • 3
    • 0021722808 scopus 로고
    • Pharmacological manipulation of the complement system
    • Asghar S. S. Pharmacological manipulation of the complement system. Pharmacol. Rev. 36:1984;223-244.
    • (1984) Pharmacol. Rev. , vol.36 , pp. 223-244
    • Asghar, S.S.1
  • 4
    • 0029079605 scopus 로고
    • Complement biosynthesis in the central nervous system
    • Barnum S. R. Complement biosynthesis in the central nervous system. Crit. Rev. Oral. Biol. Med. 6:1995;132-139.
    • (1995) Crit. Rev. Oral. Biol. Med. , vol.6 , pp. 132-139
    • Barnum, S.R.1
  • 5
    • 0032479929 scopus 로고    scopus 로고
    • Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide
    • Bradt B. M., Kilb W. P., Cooper N. R. Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. J. Exp. Med. 188:1998;431-438.
    • (1998) J. Exp. Med. , vol.188 , pp. 431-438
    • Bradt, B.M.1    Kilb, W.P.2    Cooper, N.R.3
  • 6
    • 0030000385 scopus 로고    scopus 로고
    • The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
    • Breitner J. C. S. The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu. Rev. Med. 47:1996;401-411.
    • (1996) Annu. Rev. Med. , vol.47 , pp. 401-411
    • Breitner, J.C.S.1
  • 8
    • 0020059452 scopus 로고
    • Demonstration of neurofibrillary tangles in paraffin sections. A quick and simple method using Palmgrens method
    • Cross R. B. Demonstration of neurofibrillary tangles in paraffin sections. A quick and simple method using Palmgrens method. Med. Lab. Sci. 39:1982;67-69.
    • (1982) Med. Lab. Sci. , vol.39 , pp. 67-69
    • Cross, R.B.1
  • 10
    • 0013141948 scopus 로고
    • Human complement component C3: CDNA coding sequence and derived primary structure
    • DeBruijn M. H. L., Fey G. H. Human complement component C3: cDNA coding sequence and derived primary structure. Proc. Natl. Acad. Sci. USA. 82:1985;708-712.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 708-712
    • Debruijn, M.H.L.1    Fey, G.H.2
  • 15
    • 0031031213 scopus 로고    scopus 로고
    • Expression of the receptor for complement C5a (CD88) is upregulated on reactive astrocytes, microglia and endothelial cells in inflammed human central nervous system
    • Gasque P., Singhrao S. K., Neal J. W., Gotze O., Morgan B. P. Expression of the receptor for complement C5a (CD88) is upregulated on reactive astrocytes, microglia and endothelial cells in inflammed human central nervous system. Am. J. Pathol. 150:1997;31-41.
    • (1997) Am. J. Pathol. , vol.150 , pp. 31-41
    • Gasque, P.1    Singhrao, S.K.2    Neal, J.W.3    Gotze, O.4    Morgan, B.P.5
  • 16
    • 0008437309 scopus 로고    scopus 로고
    • C3aR is a marker of inflammation and gliosis in human neurodegenerative disorders
    • Gasque P., Singhrao S. K., Neal J. W., Morgan B. P. C3aR is a marker of inflammation and gliosis in human neurodegenerative disorders. Mol. Immunol. 35:1998;380.
    • (1998) Mol. Immunol. , vol.35 , pp. 380
    • Gasque, P.1    Singhrao, S.K.2    Neal, J.W.3    Morgan, B.P.4
  • 17
    • 0032055221 scopus 로고    scopus 로고
    • The receptor for complement anaphylatoxin C3a is expressed by Myeloid cells and nonmyeloid cells in inflamed human central nervous system: Analysis in multiple sclerosis and bacterial meningitis
    • Gasque P., Singhrao S. K., Neal J. W., Wang P., Sayah S., Fontaine M., Morgan B. P. The receptor for complement anaphylatoxin C3a is expressed by Myeloid cells and nonmyeloid cells in inflamed human central nervous system: Analysis in multiple sclerosis and bacterial meningitis. J. Immunol. 160:1998;3543-3547.
    • (1998) J. Immunol. , vol.160 , pp. 3543-3547
    • Gasque, P.1    Singhrao, S.K.2    Neal, J.W.3    Wang, P.4    Sayah, S.5    Fontaine, M.6    Morgan, B.P.7
  • 18
    • 0028863749 scopus 로고
    • Identification and characterisation of the complement C5a anaphylatoxin receptor on human astrocytes
    • Gasque P., Chan P., Fontaine M., Ischenko A., Lamacz M., Gotze O., Morgan B. P. Identification and characterisation of the complement C5a anaphylatoxin receptor on human astrocytes. J. Immunol. 155:1995;4882-4888.
    • (1995) J. Immunol. , vol.155 , pp. 4882-4888
    • Gasque, P.1    Chan, P.2    Fontaine, M.3    Ischenko, A.4    Lamacz, M.5    Gotze, O.6    Morgan, B.P.7
  • 19
    • 0032536444 scopus 로고    scopus 로고
    • Identification of an astrocyte cell population from human brain that expresses perforin, a cytotoxic protein implicated in immune defense
    • Gasque P., Jones J., Singhrao S. K., Morgan B. P. Identification of an astrocyte cell population from human brain that expresses perforin, a cytotoxic protein implicated in immune defense. J. Exp. Med. 187:1998;451-460.
    • (1998) J. Exp. Med. , vol.187 , pp. 451-460
    • Gasque, P.1    Jones, J.2    Singhrao, S.K.3    Morgan, B.P.4
  • 20
    • 0028136177 scopus 로고
    • CR3/43, a marker for activated human microglia: Application to diagnostic neuropathology
    • Graeber M. B., Bise K., Mehraein P. CR3/43, a marker for activated human microglia: application to diagnostic neuropathology. Neuropathol. Appl. Neurobiol. 20:1994;406-408.
    • (1994) Neuropathol. Appl. Neurobiol. , vol.20 , pp. 406-408
    • Graeber, M.B.1    Bise, K.2    Mehraein, P.3
  • 21
    • 0021982117 scopus 로고
    • Evidence for degenerative changes in neostriatal spiny neurons in Huntington's disease
    • Graveland G. A., Williams R., DiFiglia M. Evidence for degenerative changes in neostriatal spiny neurons in Huntington's disease. Science. 227:1985;770-773.
    • (1985) Science , vol.227 , pp. 770-773
    • Graveland, G.A.1    Williams, R.2    Difiglia, M.3
  • 22
    • 0031414142 scopus 로고    scopus 로고
    • Therapeutic strategies for Huntington's disease based on a molecular understanding of the disorder
    • Haque N. S. K., Borghesani P., Isacson O. Therapeutic strategies for Huntington's disease based on a molecular understanding of the disorder. Molec. Med. Today. 4:1997;175-183.
    • (1997) Molec. Med. Today , vol.4 , pp. 175-183
    • Haque, N.S.K.1    Borghesani, P.2    Isacson, O.3
  • 24
    • 0027480960 scopus 로고
    • Cell. 72:1993;971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 25
    • 0030769914 scopus 로고    scopus 로고
    • A highly sensitive detection method for immunohistochemistry using biotinylated tyramine
    • King G., Payne S., Walker F., Murray G. I. A highly sensitive detection method for immunohistochemistry using biotinylated tyramine. J. Pathol. 183:1997;237-241.
    • (1997) J. Pathol. , vol.183 , pp. 237-241
    • King, G.1    Payne, S.2    Walker, F.3    Murray, G.I.4
  • 27
    • 0032555066 scopus 로고    scopus 로고
    • Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
    • Matthews R. T., Yang L., Browne S., Baik M., Beal M. F. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc. Natl. Acad. Sci. USA. 95:1998;8892-8897.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8892-8897
    • Matthews, R.T.1    Yang, L.2    Browne, S.3    Baik, M.4    Beal, M.F.5
  • 28
    • 0029610011 scopus 로고
    • The inflammatory response system of the brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer P. L., McGeer E. G. The inflammatory response system of the brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Rev. 21:1995;195-218.
    • (1995) Brain Res. Rev. , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 30
    • 0030271257 scopus 로고    scopus 로고
    • Expression of complement in the brain: Role in health and disease
    • Morgan B. P., Gasque P. Expression of complement in the brain: Role in health and disease. Immunol. Today. 17:1996;461-466.
    • (1996) Immunol. Today , vol.17 , pp. 461-466
    • Morgan, B.P.1    Gasque, P.2
  • 32
    • 0029973611 scopus 로고    scopus 로고
    • Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease
    • Obanion M. K., Finch C. E. Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease. Neurobiol. Aging. 17:1996;669-673.
    • (1996) Neurobiol. Aging , vol.17 , pp. 669-673
    • Obanion, M.K.1    Finch, C.E.2
  • 33
    • 0030250826 scopus 로고    scopus 로고
    • Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: The role of the Complement system
    • Pasinetti G. M. Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: The role of the Complement system. Neurobiol. Aging. 17:1996;707-716.
    • (1996) Neurobiol. Aging , vol.17 , pp. 707-716
    • Pasinetti, G.M.1
  • 34
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington's disease and excitotoxic animal models
    • Portera-Cailliau C., Hedreen J. C., Price D. L., Koliatsos V. E. Evidence for apoptotic cell death in Huntington's disease and excitotoxic animal models. J. Neurosci. 15:1995;3775-3787.
    • (1995) J. Neurosci. , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.E.4
  • 38
    • 0344244070 scopus 로고    scopus 로고
    • The complement system
    • eds. L. Collier, A. Balowest Sussmann. Complement, chapter 4 Arnold Publishers, London
    • Sim, R. B.1998. The complement system. In Topley and Wilsons Microbiology and Microbial Infections. 9th Edition, vol 3. eds. L. Collier, A. Balowest Sussmann. Complement, chapter 4, pages 37-45. Arnold Publishers, London.
    • (1998) In Topley and Wilsons Microbiology and Microbial Infections. 9th Edition , vol.3 , pp. 37-45
    • Sim, R.B.1
  • 40
    • 0032052003 scopus 로고    scopus 로고
    • Huntingtin protein colocalises with lesions of neurodegenerative diseases: An investigation in Huntington's, Alzheimer's and Pick's disease
    • Singhrao S. K., Thomas P., Wood J. D., MacMillan J. C., Neal J. W., Harper P. S., Jones A. L. Huntingtin protein colocalises with lesions of neurodegenerative diseases: an investigation in Huntington's, Alzheimer's and Pick's disease. Exp. Neurol. 150:1998;213-222.
    • (1998) Exp. Neurol. , vol.150 , pp. 213-222
    • Singhrao, S.K.1    Thomas, P.2    Wood, J.D.3    MacMillan, J.C.4    Neal, J.W.5    Harper, P.S.6    Jones, A.L.7
  • 43
    • 0028898594 scopus 로고
    • Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP-2) in the hypoglossal nucleus following peripheral nerve injury
    • Svensson M., Liu L., Mattsson P., Morgan B. P., Aldskogius H. Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP-2) in the hypoglossal nucleus following peripheral nerve injury. Mol. Chem. Neuropathol. 24:1995;53-68.
    • (1995) Mol. Chem. Neuropathol. , vol.24 , pp. 53-68
    • Svensson, M.1    Liu, L.2    Mattsson, P.3    Morgan, B.P.4    Aldskogius, H.5
  • 44
    • 0026766293 scopus 로고
    • The effect of axon injury on microtubule-associated protein MAP2 mRNA in the hypoglossal nucleus of the adult rat
    • Svensson M., Aldskogius H. The effect of axon injury on microtubule-associated protein MAP2 mRNA in the hypoglossal nucleus of the adult rat. Brain Res. 581:1992;319-322.
    • (1992) Brain Res. , vol.581 , pp. 319-322
    • Svensson, M.1    Aldskogius, H.2
  • 47
    • 0031031747 scopus 로고    scopus 로고
    • Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's disease pathogenesis
    • Velazquez P., Cribbs D. H., Poulos T. L., Tenner A. J. Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's disease pathogenesis. Nature Med. 3:1997;77-79.
    • (1997) Nature Med. , vol.3 , pp. 77-79
    • Velazquez, P.1    Cribbs, D.H.2    Poulos, T.L.3    Tenner, A.J.4
  • 50
    • 0028923898 scopus 로고
    • Complement and cytokine gene expression in cultured microglia derived from postmortem human brains
    • Walker D. G., Kim S. U., McGeer P. L. Complement and cytokine gene expression in cultured microglia derived from postmortem human brains. J. Neurosci. Res. 40:1995;478-493.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 478-493
    • Walker, D.G.1    Kim, S.U.2    McGeer, P.L.3
  • 53
    • 0030787762 scopus 로고    scopus 로고
    • Towards understanding the molecular pathology of Huntingtons disease
    • Wellington C., Brinkman J. R., Kusky O., Hayden M. R. Towards understanding the molecular pathology of Huntingtons disease. Brain Pathol. 7:1997;979-1002.
    • (1997) Brain Pathol. , vol.7 , pp. 979-1002
    • Wellington, C.1    Brinkman, J.R.2    Kusky, O.3    Hayden, M.R.4
  • 54
    • 0028278052 scopus 로고
    • Expression of the complement membrane attack complex and its inhibitors in Pick disease brain
    • Yasuhara O., Yoshinari A., McGeer E., McGeer P. L. Expression of the complement membrane attack complex and its inhibitors in Pick disease brain. Brain Res. 652:1994;346-349.
    • (1994) Brain Res. , vol.652 , pp. 346-349
    • Yasuhara, O.1    Yoshinari, A.2    McGeer, E.3    McGeer, P.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.