Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

NeuroImage

Volumn 40, Issue 1, 2008, Pages 43-52

  Fujita, Masahiro ^a   Imaizumi, Masao ^a   Zoghbi, Sami S ^a   Fujimura, Yota ^a   Farris, Amanda G ^a   Suhara, Tetsuya ^b   Hong, Jinsoo ^a   Pike, Victor W ^a   Innis, Robert B ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Aryloxyanilide; Compartmental analysis; Distribution volume; Microglia; Monte Carlo simulation

Indexed keywords

BENZODIAZEPINE RECEPTOR; BIOLOGICAL MARKER; CARBON 11; PERIPHERAL BENZODIAZEPINE RECEPTOR 28 C 11; RADIOLIGAND; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BRAIN ARTERY; BRAIN SCINTISCANNING; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; FEMALE; HUMAN; INFLAMMATION; KIDNEY; KINETICS; LUNG; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING;

ADULT; BIOLOGICAL MARKERS; BIOTRANSFORMATION; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFLAMMATION; MAGNETIC RESONANCE IMAGING; MALE; MODELS, STATISTICAL; MONTE CARLO METHOD; PERIPHERAL NERVES; POSITRON-EMISSION TOMOGRAPHY; PYRIMIDINES; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; REPRODUCIBILITY OF RESULTS;

EID: 38949112843     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2007.11.011     Document Type: Article

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