Selective induction of interleukin-6 in mouse microglia by granulocyte-macrophage colony-stimulating factor

Brain Research

Volumn 713, Issue 1-2, 1996, Pages 192-198

  Suzumura, Akio ^a,b   Sawada, Makoto ^b   Marunouchi, Tohru ^b  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

astrocyte; cytokine; granulocyte macrophage colony stimulating factor; interleukin 6; microglia

Indexed keywords

CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; MICROGLIA; MOUSE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0029981358     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01535-3     Document Type: Article

References (47)

1. Aloisi, F., Care, A., Borsellino, G., Gallo, P., Rosa, S., Bassani, A., Caibbo, A., Testa, U., Levi, G. and Perscle, C., Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1beta and tumor necrosis factor-alpha, J. Immunol., 149 (1992) 2358-2366.
2. Bauer, J., Strauss, S., Schreiter-Gasser, U., Ganter, U., Schlegel, P., Witt, I., Volk, B. and Berger, M., Interleukin-6 and a-2-macroglobulin indicate an acute phase state in Alzheimer's disease cortices, FEBS Lett., 285 (1991) 111-114.
3. Benveniste, E.N., Sparacio, S.M., Norris, J.G., Grenett, H.E. and Fuller, G.M., Induction and regulation of interleukin-6 gene expression in rat astrocytes, J. Neuroimmunol., 30 (1990) 201-212.
4. Chomezynski, P. and Sacchi, N., Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162 (1987) 156-159.
5. Constam, D.B., Philipp, J., Malipiero, U.V., Ten Dijke, P., Schachner, M. and Fontana, A., Differential expression of transforming growth factor-β1, β2, and β3 by glioblastoma cell, astrocytes, and microglia, J. Immunol., 148 (1992) 1404-1410.
6. Farrar, W.L., Vinocour, M. and Hill, J.M., In situ hybridization histochemistry localization of interleukin-3 mRNA in mouse brain, Blood, 73 (1989) 137-140.
7. Frei, K., Malipiero, U.V., Leist, T.P., Zinkernagel, R.M., Schwab, M.E. and Fontana, A., On the cellular source and function of interleukin-6 produced in the central nervous system in viral diseases, Eur. J. Immunol., 19 (1989) 689-694.
8. Gadient, R.A. and Otten, U., Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development, Brain Res., 637 (1994) 10-14.
9. Gebicke-Haeter, P.J., Appel, K., Taylor, G.D., Schobert, A., Rich, I.N., Northoff, H. and Berger, M., Rat microglial interleukin-3, J. Neuroimmunol., 50 (1994) 203-214.
10. Gitter, B.D., Regoli, D., Howbert, J.J., Glasebrook, A.L. and Waters, D.C., Interleukin-6 secretion from human astrocytoma cell induced by substance P, J. Neuroimmunol., 51 (1994) 101-108.
11. Giulian, D., Baker, T.J., Shin, L.C.N. and Lachman, L.B., Interleukin-1 of the central nervous system is produced by ameboid microglia, J. Exp. Med., 164 (1986) 594-604.
12. Hama, T., Miyamoto, M., Tsukui, H., Nishio, C. and Hatanaka, H., Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons form postnatal rat, Neurosci. Lett., 104 (1989) 340-344.
13. Helfgott, D.C., May, L.T., Sthoeger, Z., Tamm, I. and Sehgal, P.B., Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts, J. Exp. Med., 186 (1987) 1300-1309.
14. Hirano, T., Akira, S., Taga, V.T., and Kishimoto, T., Biological and clinical aspects of interleukin-6, Immunol. Today, 11 (1990) 443-449.
15. Hirohata, S. and Miyamoto, T., Elevated levels of inteleukin-6 in cerebrospinal fluid from patients with systemic lupus erythematosus and central nervous system involvement, Arthritis Rheum., 33 (1990) 644-649.
16. Hopkins, S.J. and Humphrey, M., Simple, sensitive and specific bioassay of interleukin-1, J. Immunol. Methods, 120 (1989) 271-276.
17. Horii, Y., Muraguchi, A., Suematu, S., Matsuda, T., Yoshizaki, K., Hirano, T. and Kishimoto, T., Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells, J. Immunol., 141 (1988) 1529-1535.
18. Imamura, K., Suzumura, A., Sawada, M. and Marunouchi, T., Interleukin -3 induce class II MHC antigen expression in microglia, J. Neuroimmunol, 55 (1994) 119-125.
19. Kamegai, M., Konishi, Y. and Tabira, T., Trophic effect of granulocyte-macrophage colony-stimulating factor on central cholinergic neurons in vitro, Brain Res., 532 (1990) 323-325.
20. Laurenzi, M.A., Siden, A., Persson, M.A.A., Norkkrans, G., Hagberg, L. and Chiodi, F., Cerebrospinal fluid interleukin-6 activity in HIV infection and inflammatory and noninflammatory diseases of the nervous system, Clin. Immunol Immunopathol., 57 (1990) 233-241.
21. Lieberman, A., Pitha, P.M., Shin, H. and Shin, M., Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus, Proc. Natl. Acad. Sci. USA, 86 (1989) 6348-6352.
22. Malipiero, V.V., Frei, K. and Fontana, A., Production of hemopoietic colony-stimulating factors by astrocytes, J. Immunol., 144 (1990) 3816-3821.
23. Matsuda, T., Hirano, T. and Kishimoto, T., Establishment of interleukin 6(IL-6)/B cell stimulatory factor 2(BSF-2)-dependent cell line and preparation of anti-IL-6/BSF-2 monoclonal antibodies, Eur. J. Immunol., 18 (1988) 951-956.
24. Mizuno, T., Sawada, M., Suzumura, A. and Marunouchi, T., Expression of cytokines during glial differentiation, Brain Res., 656 (1994a) 141-146.
25. Mizuno, T., Sawada, M., Marunouchi, T. and Suzumura, A., Production of interleukin-10 by mouse glial cells in culture, Biochem. Biophys. Res. Commun., 205 (1994b) 1907-1915.
26. Nakajima, K., Martinez-Maza, O., Hirano, T., Nishamian, P., Salazar-Gonalez, J.F., Fahey, J.L. and Kishimoto, T., Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV, J. Immunol., 142 (1989) 531-536.
27. Navarro, S., Debili, N., Bernaudin, J., Vainchenker, W. and Doly, J., Regulation of the expression of IL-6 in human monocytes, J. Immunol., 142 (1989) 4339-4345.
28. Nishimoto, N., Yoshizaki, K., Eiraku, N., Machigashira, K., Tagoh, H., Ogata, A., Kuritani, T., Osame, M., and Kishimoto, T., Elevated levels of interleukin-6 in serum and cerebrospinal fluid of HTLV-1-associated myelopathy/tropical spastic paraparesis, J. Neurol. Sci., 97 (1990) 183-193.
29. Ohno, K., Suzumura, A., Sawada, M., and Marunouchi, T., Production of granulocyte/macrophage colony-stimulating factor by cultured astrocytes, Biochem. Biophys. Res. Commun., 169 (1990) 719-724.
30. Raivich, G., Gehrmann, J. and Kreutzberg, G.W., Increase of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor receptors in the regenerating rat facial nucleus, J. Neurosci. Res., 30 (1991) 682-686.
31. Righi, M., Mori, L., Deliberao, G., Stironi, M., Biondi, A., Mantovani, A. Donini, S.D. and Ricciardi-Castagnoli, P., Monokine production by microglial cell clones, Eur. J. Immunol., 19 (1989) 1443-1448.
32. Sawada, M., Kondo, N., Suzumura, A. and Marunouchi, T., Production of tumor necrosis factor-alpha by microglia and astrocyte in culture, Brain Res., 491 (1989) 394-397.
33. Sawada, M., Suzumura, A., Yamamoto, H. and Marunouchi, T., Activation and proliferation of the isolated microglia by colony-stimulating factor-1 and possible involvement of protein kinase C, Brain Res., 509 (1990) 119-124.
34. Sawada, M., Suzumura, A. and Marunouchi, T., TNF alpha induces IL-6 production by astrocytes but not by microglia, Brain Res., 583 (1992) 296-299.
35. Sawada, M., Itoh, Y., Suzumura, A. and Marunouchi, T., Expression of cytokine receptors in cultured neuronal and glial cells, Neurosci. Lett., 160 (1993a) 131-134.
36. Sawada, M., Suzumura, A., Itoh, Y. and Marunouchi, T., Production of interleukin-5 by mouse astrocytes and microglia in culture, Neurosci. Lett., 155 (1993a) 175-178.
37. Schöbitz, B., Voorhuis, D.A.M. and DeKloet, E.R., Localization of interleukin-6 mRNA and interleukin-6 receptor mRNA in rat brain, Neurosci. Lett., 136 (1992) 189-192.
38. Strauss, S., Bauer, J., Ganter, U., Jonas, U., Berger, M. and Volk, B., Detection of interleukin-6 and a2-macroglobulin immunoreactibity in cortex and hippocampus of Alzheimer's disease patients, Lab. Invest., 66 (1992) 223-230.
39. Suzumura, A., Bhat, S., Eccleston, P.A., Lisak, R.P., and Silberberg, D.H., The isolation and long-term culture of oligodendrocytes from newborn mouse brain, Brain Res., 324 (1984) 379-383.
40. Suzumura, A., Mezitis, S.G.E., Gonatas, N.K. and Silberberg, D.H., MHC antigen expression on bulk isolated macrophage-microglia in vitro:induction of class II MHC antigen expression by interferon-γ, J. Neuroimmunol., 15 (1987) 263-278.
41. Suzumura, A., Lavi, E., Bhat, S., Murasko, D., Weiss, S.R. and Silberberg, D.H., Induction of glial cell MHC antigen expression in neurotropic corona virus infection: characterization of the H-2 inducing soluble factor elaborated by infected brain cells, J. Immunol., 140 1988) 2068-2072.
42. Suzumura, A., Sawada, M., Yamamoto, H. and Marunouchi, T., Effects of colony-stimulating factors on isolated microglia in vitro, J. Neuroimmunol., 30 (1990) 111-120.
43. Suzumura, A., Marunouchi, T. and Yamamoto, H., Morphological transformation of microglia in vitro, Brain Res., 545 (1991) 301-306.
44. Suzumura, A., Sawada, M., Yamamoto, H., and Marunouchi, T., Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro, J. Immunol., 151 (1993) 2150-2158.
45. Treardy, D.J., Mott, P.L. and Glazer, E.W., Monokine modulation of human astroglial cell production of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor, J. Immunol., 144 (1990) 2233-2241.
46. Wahl, S.M., Allen, J.B., McCatney-Francis, N., Morganti-Kossmann, M.C., Kossmann, T., Ellingsworth, L., Mai, U.E.H., Mergenhagen, S.E. and Orenstein, J.M., Macrophage-and astrocyte-derived transforming growth factor b as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome, J. Exp. Med., 173 (1991) 981-991.
47. Yan, H.Q., Alcaros Banos, M., Herregodts, P., Hooghe, R. and Hooghe-Peters, E.L., Expression of interleukin(IL)-1β, IL-6 and their respective receptors in the normal rat brain and after injury, Eur. J. Immunol., 22 (1992) 2963-2971.