-
1
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H., et al. Inflammation and Alzheimer's disease. Neurobiol. Aging 21 (2000) 383-421
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
-
2
-
-
34247225480
-
A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195
-
Anderson A.N., et al. A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195. Neuroimage 36 (2007) 28-37
-
(2007)
Neuroimage
, vol.36
, pp. 28-37
-
-
Anderson, A.N.1
-
3
-
-
33745700402
-
Amyloid load and cerebral atrophy in Alzheimer's disease: An (11)C-PIB positron emission tomography study
-
Archer H.A., et al. Amyloid load and cerebral atrophy in Alzheimer's disease: An (11)C-PIB positron emission tomography study. Ann. Neurol. 60 (2006) 145-147
-
(2006)
Ann. Neurol.
, vol.60
, pp. 145-147
-
-
Archer, H.A.1
-
4
-
-
0033768486
-
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity
-
Banati R.B., et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain 123 Pt 11 (2000) 2321-2337
-
(2000)
Brain
, vol.123
, Issue.PART 11
, pp. 2321-2337
-
-
Banati, R.B.1
-
5
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F., et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6 (2000) 916-919
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
-
6
-
-
0034128874
-
The peripheral benzodiazepine receptors: a review
-
Beurdeley-Thomas A., et al. The peripheral benzodiazepine receptors: a review. J. Neurooncol. 46 (2000) 45-56
-
(2000)
J. Neurooncol.
, vol.46
, pp. 45-56
-
-
Beurdeley-Thomas, A.1
-
7
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., and Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl). 82 (1991) 239-259
-
(1991)
Acta Neuropathol. (Berl).
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
8
-
-
9844227354
-
Performance evaluation of a whole-body PET scanner using the NEMA protocol. National Electrical Manufacturers Association
-
Brix G., et al. Performance evaluation of a whole-body PET scanner using the NEMA protocol. National Electrical Manufacturers Association. J. Nucl. Med. 38 (1997) 1614-1623
-
(1997)
J. Nucl. Med.
, vol.38
, pp. 1614-1623
-
-
Brix, G.1
-
9
-
-
0035845283
-
In-vivo measurement of activated microglia in dementia
-
Cagnin A., et al. In-vivo measurement of activated microglia in dementia. Lancet. 358 (2001) 461-467
-
(2001)
Lancet.
, vol.358
, pp. 461-467
-
-
Cagnin, A.1
-
10
-
-
0034774203
-
In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion
-
Cagnin A., et al. In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion. Brain 124 (2001) 2014-2027
-
(2001)
Brain
, vol.124
, pp. 2014-2027
-
-
Cagnin, A.1
-
11
-
-
0003176673
-
Microglial cell activation in aging and Alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus
-
DiPatre P.L., and Gelman B.B. Microglial cell activation in aging and Alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus. J. Neuropathol. Exp. Neurol. 56 (1997) 143-149
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 143-149
-
-
DiPatre, P.L.1
Gelman, B.B.2
-
12
-
-
33847062118
-
Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study
-
Edison P., et al. Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study. Neurology 68 (2007) 501-508
-
(2007)
Neurology
, vol.68
, pp. 501-508
-
-
Edison, P.1
-
13
-
-
0036850023
-
Neuroinflammation in Alzheimer's disease and prion disease
-
Eikelenboom P., et al. Neuroinflammation in Alzheimer's disease and prion disease. Glia 40 (2002) 232-239
-
(2002)
Glia
, vol.40
, pp. 232-239
-
-
Eikelenboom, P.1
-
14
-
-
33749506795
-
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
-
Engler H., et al. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 129 (2006) 2856-2866
-
(2006)
Brain
, vol.129
, pp. 2856-2866
-
-
Engler, H.1
-
15
-
-
33644832047
-
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans
-
Fagan A.M., et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann. Neurol. 59 (2006) 512-519
-
(2006)
Ann. Neurol.
, vol.59
, pp. 512-519
-
-
Fagan, A.M.1
-
16
-
-
0026783591
-
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
-
Frackowiak J., et al. Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol. (Berl). 84 (1992) 225-233
-
(1992)
Acta Neuropathol. (Berl).
, vol.84
, pp. 225-233
-
-
Frackowiak, J.1
-
17
-
-
0031974406
-
Microglial response to amyloid plaques in APPsw transgenic mice
-
Frautschy S.A., et al. Microglial response to amyloid plaques in APPsw transgenic mice. Am. J. Pathol. 152 (1998) 307-317
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 307-317
-
-
Frautschy, S.A.1
-
18
-
-
0029811105
-
Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia
-
Giulian D., et al. Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia. J. Neurosci. 16 (1996) 6021-6037
-
(1996)
J. Neurosci.
, vol.16
, pp. 6021-6037
-
-
Giulian, D.1
-
19
-
-
0027236235
-
Synaptic stripping in the human facial nucleus
-
Graeber M.B., et al. Synaptic stripping in the human facial nucleus. Acta Neuropathol. 86 (1993) 179-181
-
(1993)
Acta Neuropathol.
, vol.86
, pp. 179-181
-
-
Graeber, M.B.1
-
20
-
-
0041569918
-
Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe
-
Hammers A., et al. Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe. Hum. Brain Mapp. 19 (2003) 224-247
-
(2003)
Hum. Brain Mapp.
, vol.19
, pp. 224-247
-
-
Hammers, A.1
-
21
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J., and Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci. 12 (1991) 383-388
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
22
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
-
Klunk W.E., et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann. Neurol. 55 (2004) 306-319
-
(2004)
Ann. Neurol.
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
-
23
-
-
33750593789
-
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
-
Klunk W.E., et al. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 129 (2006) 2805-2807
-
(2006)
Brain
, vol.129
, pp. 2805-2807
-
-
Klunk, W.E.1
-
24
-
-
0037444535
-
The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
-
Klunk W.E., et al. The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J. Neurosci. 23 (2003) 2086-2092
-
(2003)
J. Neurosci.
, vol.23
, pp. 2086-2092
-
-
Klunk, W.E.1
-
25
-
-
0030222037
-
Microglia: a sensor for pathological events in the CNS
-
Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19 (1996) 312-318
-
(1996)
Trends Neurosci.
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
26
-
-
0030907583
-
The cerebellum in Alzheimer's disease
-
Larner A.J. The cerebellum in Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 8 (1997) 203-209
-
(1997)
Dement. Geriatr. Cogn. Disord.
, vol.8
, pp. 203-209
-
-
Larner, A.J.1
-
27
-
-
33644876596
-
Simplified quantification of Pittsburgh compound B Amyloid imaging PET studies: a comparative analysis
-
Lopresti B.J., et al. Simplified quantification of Pittsburgh compound B Amyloid imaging PET studies: a comparative analysis. J. Nucl. Med. 46 (2005) 1959-1972
-
(2005)
J. Nucl. Med.
, vol.46
, pp. 1959-1972
-
-
Lopresti, B.J.1
-
28
-
-
0034948192
-
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
-
Lue L.F., et al. Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro. Glia 35 (2001) 72-79
-
(2001)
Glia
, vol.35
, pp. 72-79
-
-
Lue, L.F.1
-
29
-
-
0024343222
-
Cerebral amyloidosis, ageing and Alzheimer's disease; a contribution from studies on Down's syndrome
-
discussion 412-4
-
Mann D.M. Cerebral amyloidosis, ageing and Alzheimer's disease; a contribution from studies on Down's syndrome. Neurobiol. Aging 10 (1989) 397-399 discussion 412-4
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 397-399
-
-
Mann, D.M.1
-
30
-
-
0024992306
-
Microglia in cerebellar plaques in Alzheimer's disease
-
Mattiace L.A., et al. Microglia in cerebellar plaques in Alzheimer's disease. Acta Neuropathol. (Berl). 80 (1990) 493-498
-
(1990)
Acta Neuropathol. (Berl).
, vol.80
, pp. 493-498
-
-
Mattiace, L.A.1
-
31
-
-
0030961544
-
Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
-
McDonald D.R., et al. Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J. Neurosci. 17 (1997) 2284-2294
-
(1997)
J. Neurosci.
, vol.17
, pp. 2284-2294
-
-
McDonald, D.R.1
-
32
-
-
0035693924
-
Inflammation, autotoxicity and Alzheimer disease
-
McGeer P.L., and McGeer E.G. Inflammation, autotoxicity and Alzheimer disease. Neurobiol. Aging 22 (2001) 799-809
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
33
-
-
0036949091
-
Local neuroinflammation and the progression of Alzheimer's disease
-
McGeer P.L., and McGeer E.G. Local neuroinflammation and the progression of Alzheimer's disease. J. Neurovirol. 8 (2002) 529-538
-
(2002)
J. Neurovirol.
, vol.8
, pp. 529-538
-
-
McGeer, P.L.1
McGeer, E.G.2
-
34
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G., et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34 (1984) 939-944
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
-
35
-
-
0028953529
-
Activation of microglial cells by beta-amyloid protein and interferon-gamma
-
Meda L., et al. Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374 (1995) 647-650
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
-
36
-
-
28944450413
-
Utilizing advanced imaging and surrogate markers across the spectrum of Alzheimer's disease
-
Mintun M.A. Utilizing advanced imaging and surrogate markers across the spectrum of Alzheimer's disease. CNS Spectr. 10 (2005) 13-16
-
(2005)
CNS Spectr.
, vol.10
, pp. 13-16
-
-
Mintun, M.A.1
-
37
-
-
0027526364
-
Peripheral-type benzodiazepine receptors
-
Parola A.L., et al. Peripheral-type benzodiazepine receptors. Life Sci. 52 (1993) 1329-1342
-
(1993)
Life Sci.
, vol.52
, pp. 1329-1342
-
-
Parola, A.L.1
-
38
-
-
27544513056
-
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B
-
Price J.C., et al. Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B. J. Cereb. Blood Flow Metab. 25 (2005) 1528-1547
-
(2005)
J. Cereb. Blood Flow Metab.
, vol.25
, pp. 1528-1547
-
-
Price, J.C.1
-
39
-
-
0036362656
-
Elucidating molecular mechanisms of Alzheimer's disease in microglial cultures
-
Rogers J., et al. Elucidating molecular mechanisms of Alzheimer's disease in microglial cultures. Ernst Schering Res. Found. Workshop (2002) 25-44
-
(2002)
Ernst Schering Res. Found. Workshop
, pp. 25-44
-
-
Rogers, J.1
-
40
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400 (1999) 173-177
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
-
41
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe D.J. The molecular pathology of Alzheimer's disease. Neuron 6 (1991) 487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
42
-
-
0028358646
-
Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats
-
Shah F., et al. Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats. Nucl. Med. Biol. 21 (1994) 573-581
-
(1994)
Nucl. Med. Biol.
, vol.21
, pp. 573-581
-
-
Shah, F.1
-
43
-
-
0033800364
-
Physical characteristics of the ECAT EXACT3D positron tomograph
-
Spinks T.J., et al. Physical characteristics of the ECAT EXACT3D positron tomograph. Phys. Med. Biol. 45 (2000) 2601-2618
-
(2000)
Phys. Med. Biol.
, vol.45
, pp. 2601-2618
-
-
Spinks, T.J.1
-
44
-
-
0036847816
-
Microglia as neuroprotective, immunocompetent cells of the CNS
-
Streit W.J. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40 (2002) 133-139
-
(2002)
Glia
, vol.40
, pp. 133-139
-
-
Streit, W.J.1
-
45
-
-
3042845492
-
Microglia and Alzheimer's disease pathogenesis
-
Streit W.J. Microglia and Alzheimer's disease pathogenesis. J. Neurosci. Res. 77 (2004) 1-8
-
(2004)
J. Neurosci. Res.
, vol.77
, pp. 1-8
-
-
Streit, W.J.1
-
46
-
-
13344293701
-
Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
-
Teller J.K., et al. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nat. Med. 2 (1996) 93-95
-
(1996)
Nat. Med.
, vol.2
, pp. 93-95
-
-
Teller, J.K.1
-
47
-
-
33847333156
-
Reference and target region modeling of [11C]-(R)-PK11195 brain studies
-
Turkheimer F.E., et al. Reference and target region modeling of [11C]-(R)-PK11195 brain studies. J. Nucl. Med. 48 (2007) 158-167
-
(2007)
J. Nucl. Med.
, vol.48
, pp. 158-167
-
-
Turkheimer, F.E.1
-
48
-
-
0037333633
-
Immune reactive cells in senile plaques and cognitive decline in AD
-
Vehmas A.K., Stewart W.F., and Troncoso J.C. Immune reactive cells in senile plaques and cognitive decline in AD. Neurobiol. Aging 24 (2003) 321-331
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 321-331
-
-
Vehmas, A.K.1
Stewart, W.F.2
Troncoso, J.C.3
-
49
-
-
15944366880
-
In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET
-
Verhoeff N.P., et al. In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET. Am. J. Geriatr. Psychiatry 12 (2004) 584-595
-
(2004)
Am. J. Geriatr. Psychiatry
, vol.12
, pp. 584-595
-
-
Verhoeff, N.P.1
-
50
-
-
0024434236
-
Ultrastructural studies of the cells forming amyloid fibers in classical plaques
-
Wisniewski H.M., et al. Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can. J. Neurol. Sci. 16 (1989) 535-542
-
(1989)
Can. J. Neurol. Sci.
, vol.16
, pp. 535-542
-
-
Wisniewski, H.M.1
-
51
-
-
0026685656
-
Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease
-
Wisniewski H.M., et al. Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease. Acta Neuropathol. (Berl). 84 (1992) 117-127
-
(1992)
Acta Neuropathol. (Berl).
, vol.84
, pp. 117-127
-
-
Wisniewski, H.M.1
-
52
-
-
0025762631
-
Lewy bodies are immunoreactive with antibodies raised to gelsolin related amyloid-Finnish type
-
Wisniewski T., et al. Lewy bodies are immunoreactive with antibodies raised to gelsolin related amyloid-Finnish type. Am. J. Pathol. 138 (1991) 1077-1083
-
(1991)
Am. J. Pathol.
, vol.138
, pp. 1077-1083
-
-
Wisniewski, T.1
-
53
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama Y., et al. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53 (2007) 337-351
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
|