메뉴 건너뛰기




Volumn 14, Issue SUPPL. 1, 2000, Pages

Cell mediators of inflammation in the Alzheimer disease brain

Author keywords

Amyloid; Astrocyte; Microglia; Protein; Removal

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; ANTIINFLAMMATORY AGENT;

EID: 0034130707     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002093-200000001-00008     Document Type: Conference Paper
Times cited : (220)

References (27)
  • 1
    • 0025162755 scopus 로고
    • Brain microglia constitutively express β-2 integrins
    • Akiyama H, McGeer PL. Brain microglia constitutively express β-2 integrins. J Neuroimmunol 1990;30:81-93.
    • (1990) J Neuroimmunol , vol.30 , pp. 81-93
    • Akiyama, H.1    McGeer, P.L.2
  • 2
    • 0030003487 scopus 로고    scopus 로고
    • Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein
    • Akiyama H, Schwab C, Kondo H, et al. Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein. Neurosci Lett 1996a;206:169-72.
    • (1996) Neurosci Lett , vol.206 , pp. 169-172
    • Akiyama, H.1    Schwab, C.2    Kondo, H.3
  • 3
    • 0030598393 scopus 로고    scopus 로고
    • The amino-terminally truncated forms of amyloid β-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients
    • Akiyama H, Kondo H, Mori H, et al. The amino-terminally truncated forms of amyloid β-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients. Neurosci Lett 1996b;219: 115-8.
    • (1996) Neurosci Lett , vol.219 , pp. 115-118
    • Akiyama, H.1    Kondo, H.2    Mori, H.3
  • 4
    • 0033557386 scopus 로고    scopus 로고
    • Occurrence of the diffuse amyloid β-protein (Aβ) deposits with numerous Aβ-containing glial cells in the cerebral cortex of patients with Alzheimer's disease
    • Akiyama H, Mori M, Saido T, Kondo H, Iked K, McGeer PL. Occurrence of the diffuse amyloid β-protein (Aβ) deposits with numerous Aβ-containing glial cells in the cerebral cortex of patients with Alzheimer's disease. Glia 1999;25:324-31.
    • (1999) Glia , vol.25 , pp. 324-331
    • Akiyama, H.1    Mori, M.2    Saido, T.3    Kondo, H.4    Iked, K.5    McGeer, P.L.6
  • 5
    • 0030038809 scopus 로고    scopus 로고
    • Scavenging of Alzheimer's amyloid β-protein by microglia in culture
    • Ard MD, Cole GM, Wei J, Mehrle AP, Fratkin JD. Scavenging of Alzheimer's amyloid β-protein by microglia in culture. J Neurosci Res 1996;43:190-202.
    • (1996) J Neurosci Res , vol.43 , pp. 190-202
    • Ard, M.D.1    Cole, G.M.2    Wei, J.3    Mehrle, A.P.4    Fratkin, J.D.5
  • 6
    • 0031785364 scopus 로고    scopus 로고
    • Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-β (Aβ) 1-42 peptide in a murine N9 microglial cell line
    • Chu T, Tran T, Yang F, Beech W, Cole GM, Frautschy SA. Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-β (Aβ) 1-42 peptide in a murine N9 microglial cell line. FEBS Lett 1998;436:439-44.
    • (1998) FEBS Lett , vol.436 , pp. 439-444
    • Chu, T.1    Tran, T.2    Yang, F.3    Beech, W.4    Cole, G.M.5    Frautschy, S.A.6
  • 7
    • 0026635173 scopus 로고
    • Phagocytosis and deposition of vascular β-amyloid in rat brains injected with Alzheimer β-amyloid
    • Frautschy SA, Cole GM, Baird A. Phagocytosis and deposition of vascular β-amyloid in rat brains injected with Alzheimer β-amyloid. Am J Pathol 1992;140:1389-99.
    • (1992) Am J Pathol , vol.140 , pp. 1389-1399
    • Frautschy, S.A.1    Cole, G.M.2    Baird, A.3
  • 8
    • 0031922062 scopus 로고    scopus 로고
    • Astrocytes containing amyloid β-protein (Aβ)-positive granules are associated with Aβ40-positive diffuse plaques in the aged human brain
    • Funato H, Yoshimura M, Yamazaki T, Saido TC. Astrocytes containing amyloid β-protein (Aβ)-positive granules are associated with Aβ40-positive diffuse plaques in the aged human brain. Am J Pathol 1998;152:983-92.
    • (1998) Am J Pathol , vol.152 , pp. 983-992
    • Funato, H.1    Yoshimura, M.2    Yamazaki, T.3    Saido, T.C.4
  • 9
    • 0029076362 scopus 로고
    • Microglia: Intrinsic immuneffector cell of the brain
    • Gehrmann J, Matsumoto Y, Kreutzberg GW. Microglia: intrinsic immuneffector cell of the brain. Brain Res Rev 1995;20:269-87.
    • (1995) Brain Res Rev , vol.20 , pp. 269-287
    • Gehrmann, J.1    Matsumoto, Y.2    Kreutzberg, G.W.3
  • 10
    • 0029811105 scopus 로고    scopus 로고
    • Specific domains of β-amyloid from Alzheimer plaque elicit neuron killing in human microglia
    • Giulian D, Haverkamp LJ, Yu JH, Karshin W, Tom D, Li J. Specific domains of β-amyloid from Alzheimer plaque elicit neuron killing in human microglia. J Neurosci 1996;16:6021-37.
    • (1996) J Neurosci , vol.16 , pp. 6021-6037
    • Giulian, D.1    Haverkamp, L.J.2    Yu, J.H.3    Karshin, W.4    Tom, D.5    Li, J.6
  • 11
    • 0027490070 scopus 로고
    • The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution
    • Hyman BT, Marzloff K, Arriagada PV. The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. J Neuropathol Exp Neurol 1993;52:594-600.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 594-600
    • Hyman, B.T.1    Marzloff, K.2    Arriagada, P.V.3
  • 12
    • 0024436506 scopus 로고
    • Relationship of microglia and astrocytes to amyloid deposits in Alzheimer disease
    • Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D. Relationship of microglia and astrocytes to amyloid deposits in Alzheimer disease. J Neuroimmunol 1989;224:173-82.
    • (1989) J Neuroimmunol , vol.224 , pp. 173-182
    • Itagaki, S.1    McGeer, P.L.2    Akiyama, H.3    Zhu, S.4    Selkoe, D.5
  • 13
    • 0027372206 scopus 로고
    • The immunopathology of Alzheimer's disease and some related disorders
    • Kalaria RN. The immunopathology of Alzheimer's disease and some related disorders. Brain Pathol 1993;3:333-47.
    • (1993) Brain Pathol , vol.3 , pp. 333-347
    • Kalaria, R.N.1
  • 14
    • 0028987883 scopus 로고
    • Macrophages and inflammatory mediators in tissue injury
    • Laskin DL, Pendino KJ. Macrophages and inflammatory mediators in tissue injury. Annu Rev Pharmacol Toxicol 1995;35:655-77.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 655-677
    • Laskin, D.L.1    Pendino, K.J.2
  • 15
    • 0026729137 scopus 로고
    • Reversible in vitro growth of Alzheimer disease β-amyloid plaques by deposition of labeled amyloid peptide
    • Maggio JE, Stimson ER, Ghilardi JR, et al. Reversible in vitro growth of Alzheimer disease β-amyloid plaques by deposition of labeled amyloid peptide. Proc Natl Acad Sci USA 1992;89:5462-6.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5462-5466
    • Maggio, J.E.1    Stimson, E.R.2    Ghilardi, J.R.3
  • 16
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 1995;21:195-218.
    • (1995) Brain Res Rev , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 17
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
    • McGeer PL, Schulzer M, McGeer EG. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 1996;47:425-32.
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1    Schulzer, M.2    McGeer, E.G.3
  • 18
    • 0028953529 scopus 로고
    • Activation of microglial cells by β-amyloid protein and interferon-γ
    • Meda L, Cassatella MA, Szendrei GI, Otvos L Jr, Baron P. Activation of microglial cells by β-amyloid protein and interferon-γ. Nature 1995;374:647-50.
    • (1995) Nature , vol.374 , pp. 647-650
    • Meda, L.1    Cassatella, M.A.2    Szendrei, G.I.3    Otvos L., Jr.4    Baron, P.5
  • 19
    • 0026635881 scopus 로고
    • Tangle-associated neuritic clusters, a new lesion in Alzheimer's disease and aging suggests that aggregates of dystrophic neuntes are not necessarily associated with β/A4
    • Munoz DG, Wang D. Tangle-associated neuritic clusters, a new lesion in Alzheimer's disease and aging suggests that aggregates of dystrophic neuntes are not necessarily associated with β/A4. Am J Pathol 1992;140:1167-78.
    • (1992) Am J Pathol , vol.140 , pp. 1167-1178
    • Munoz, D.G.1    Wang, D.2
  • 20
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via scavenger receptor
    • Paresce DM, Ghosh RN, Maxfield FR. Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via scavenger receptor. Neuron 1996;17:553-65.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 21
    • 0030664076 scopus 로고    scopus 로고
    • Slow degradation of aggregates of the Alzheimer's disease amyloid β-protein by microglial cells
    • Paresce DM, Chung H, Maxfield FR. Slow degradation of aggregates of the Alzheimer's disease amyloid β-protein by microglial cells. J Biol Chem 1997;272:29390-7.
    • (1997) J Biol Chem , vol.272 , pp. 29390-29397
    • Paresce, D.M.1    Chung, H.2    Maxfield, F.R.3
  • 22
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D, Barbour R, Dunn W, Gordon G. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999;400:173-7.
    • (1999) Nature , vol.400 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3    Gordon, G.4
  • 23
    • 0028267440 scopus 로고
    • Normal and abnormal biology of the β-amyloid precursor protein
    • Selkoe DJ. Normal and abnormal biology of the β-amyloid precursor protein. Annu Rev Neurosci 1994;17:489-517.
    • (1994) Annu Rev Neurosci , vol.17 , pp. 489-517
    • Selkoe, D.J.1
  • 25
    • 0025752360 scopus 로고
    • Phagocytosis of β/A4 amyloid fibrils of the neuritic neocortical plaques
    • Wisniewski HM, Barcikowska M, Kida E. Phagocytosis of β/A4 amyloid fibrils of the neuritic neocortical plaques. Acta Neuropathol 1991;81:588-90.
    • (1991) Acta Neuropathol , vol.81 , pp. 588-590
    • Wisniewski, H.M.1    Barcikowska, M.2    Kida, E.3
  • 26
    • 0025906991 scopus 로고
    • Extracellular neurofibrillary tangles associated with degenerating neuntes and neuropil threads in Alzheimer-type dementia
    • Yamaguchi H, Nakazato Y, Kawaraqbayashi T, Hirai S. Extracellular neurofibrillary tangles associated with degenerating neuntes and neuropil threads in Alzheimer-type dementia. Acta Neuropathol 1991;81:603-9.
    • (1991) Acta Neuropathol , vol.81 , pp. 603-609
    • Yamaguchi, H.1    Nakazato, Y.2    Kawaraqbayashi, T.3    Hirai, S.4
  • 27
    • 0031886976 scopus 로고    scopus 로고
    • Diffuse plaques associated with astroglial amyloid protein, possibly showing a disappearing of senile plaques
    • Yamaguchi H, Sugihara S, Ogawa A, Saido TC, Ihara Y. Diffuse plaques associated with astroglial amyloid protein, possibly showing a disappearing of senile plaques. Acta Neuropathol 1998;95:217-22.
    • (1998) Acta Neuropathol , vol.95 , pp. 217-222
    • Yamaguchi, H.1    Sugihara, S.2    Ogawa, A.3    Saido, T.C.4    Ihara, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.