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Volumn 29, Issue 1, 2014, Pages 41-48

Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis

Author keywords

crystal nephropathy; dendritic cells; glomerulonephritis; macrophages; tubular injury

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84892754061     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gft332     Document Type: Review
Times cited : (171)

References (63)
  • 1
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature 2008; 454: 428-435
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 2
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010; 140: 805-820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 3
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140: 821-832
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 4
    • 84859405717 scopus 로고    scopus 로고
    • Signaling by myeloid C-type lectin receptors in immunity and homeostasis
    • Sancho D, Reis e Sousa C. Signaling by myeloid C-type lectin receptors in immunity and homeostasis. Annu Rev Immunol 2012; 30: 491-529
    • (2012) Annu Rev Immunol , vol.30 , pp. 491-529
    • Sancho, D.1    Reise Sousa, C.2
  • 5
    • 77956103055 scopus 로고    scopus 로고
    • Quantitative expression of RIG-like helicase. NOD-like receptor and inflamma-some-related mRNAs in humans and mice
    • Lech M, Avila-Ferrufino A, Skuginna V et al. Quantitative expression of RIG-like helicase, NOD-like receptor and inflamma-some-related mRNAs in humans and mice. Int Immunol 2010; 22: 717-728
    • (2010) Int Immunol , vol.22 , pp. 717-728
    • Lech, M.1    Avila-Ferrufino, A.2    Skuginna, V.3
  • 7
    • 1642275654 scopus 로고    scopus 로고
    • Signaling danger: Toll-like receptors and their potential roles in kidney disease
    • Anders HJ, Banas B, Schlondorff D. Signaling danger: toll-like receptors and their potential roles in kidney disease. J Am Soc Nephrol 2004; 15: 854-867
    • (2004) J Am Soc Nephrol , vol.15 , pp. 854-867
    • Anders, H.J.1    Banas, B.2    Schlondorff, D.3
  • 8
    • 79957773993 scopus 로고    scopus 로고
    • The inflammasomes in kidney disease
    • Anders HJ, Muruve DA. The inflammasomes in kidney disease. J Am Soc Nephrol 2011; 22: 1007-1018
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1007-1018
    • Anders, H.J.1    Muruve, D.A.2
  • 9
    • 84869504451 scopus 로고    scopus 로고
    • Inflammasomes and their roles in health and disease
    • Lamkanfi M, Dixit VM. Inflammasomes and their roles in health and disease. Annu Rev Cell Dev Biol 2012; 28: 137-161
    • (2012) Annu Rev Cell Dev Biol , vol.28 , pp. 137-161
    • Lamkanfi, M.1    Dixit, V.M.2
  • 10
    • 69549086803 scopus 로고    scopus 로고
    • Evolution and functional divergence of NLRP genes in mammalian reproductive systems
    • Tian X, Pascal G, Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive systems. BMC Evol Biol 2009; 9: 202
    • (2009) BMC Evol Biol , vol.9 , pp. 202
    • Tian, X.1    Pascal, G.2    Monget, P.3
  • 12
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity, 2007; 27: 549-559
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 13
    • 80455176839 scopus 로고    scopus 로고
    • Non-canonical inflammasome activation targets caspase-11
    • Kayagaki N, Warming S, Lamkanfi M et al. Non-canonical inflammasome activation targets caspase-11. Nature, 2011; 479: 117-121
    • (2011) Nature , vol.479 , pp. 117-121
    • Kayagaki, N.1    Warming, S.2    Lamkanfi, M.3
  • 14
    • 77957554717 scopus 로고    scopus 로고
    • Molecular mechanism of NLRP3 inflammasome activation
    • Jin C, Flavell RA. Molecular mechanism of NLRP3 inflammasome activation. J Clin Immunol, 2010; 30: 628-631
    • (2010) J Clin Immunol , vol.30 , pp. 628-631
    • Jin, C.1    Flavell, R.A.2
  • 15
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through pha-gosomal destabilization
    • Hornung V, Bauernfeind F, Halle A et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through pha-gosomal destabilization. Nat Immunol 2008; 9: 847-856
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3
  • 16
    • 79956358982 scopus 로고    scopus 로고
    • Polyene macro-lide antifungal drugs trigger interleukin-1beta secretion by activating the NLRP3 inflammasome
    • Darisipudi MN, Allam R, Rupanagudi KV et al. Polyene macro-lide antifungal drugs trigger interleukin-1beta secretion by activating the NLRP3 inflammasome. PLoS One 2011; 6: e19588
    • (2011) PLoS One , vol.6
    • Darisipudi, M.N.1    Allam, R.2    Rupanagudi, K.V.3
  • 17
    • 79952747168 scopus 로고    scopus 로고
    • Cutting edge: Cyclic polypeptide and aminoglycoside antibiotics trigger IL-1beta secretion by activating the NLRP3 inflammasome
    • Allam R, Darisipudi MN, Rupanagudi KV et al. Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1beta secretion by activating the NLRP3 inflammasome. J Immunol 2011; 186: 2714-2718
    • (2011) J Immunol , vol.186 , pp. 2714-2718
    • Allam, R.1    Darisipudi, M.N.2    Rupanagudi, K.V.3
  • 18
    • 84868618082 scopus 로고    scopus 로고
    • Uromodulin triggers IL-1beta-dependent innate immunity via the NLRP3 inflammasome
    • Darisipudi MN, Thomasova D, Mulay SR et al. Uromodulin triggers IL-1beta-dependent innate immunity via the NLRP3 inflammasome. J Am Soc Nephrol 2012; 23: 1783-1789
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1783-1789
    • Darisipudi, M.N.1    Thomasova, D.2    Mulay, S.R.3
  • 19
    • 84873827527 scopus 로고    scopus 로고
    • Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1beta secretion
    • Mulay SR, Kulkarni OP, Rupanagudi KV et al. Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1beta secretion. J Clin Invest 2013; 123: 236-246
    • (2013) J Clin Invest , vol.123 , pp. 236-246
    • Mulay, S.R.1    Kulkarni, O.P.2    Rupanagudi, K.V.3
  • 20
    • 80055053463 scopus 로고    scopus 로고
    • Anti-GBM glomeru-lonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1
    • Lichtnekert J, Kulkarnit OP, Mulay SR et al. Anti-GBM glomeru-lonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. PLoS One 2011; 6: e26778
    • (2011) PLoS One , vol.6
    • Lichtnekert, J.1    Kulkarnit, O.P.2    Mulay, S.R.3
  • 21
    • 0036846099 scopus 로고    scopus 로고
    • Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis
    • Faust J, Menke J, Kriegsmann J et al. Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis. Arthritis Rheum 2002; 46: 3083-3095
    • (2002) Arthritis Rheum , vol.46 , pp. 3083-3095
    • Faust, J.1    Menke, J.2    Kriegsmann, J.3
  • 22
    • 80052760761 scopus 로고    scopus 로고
    • Interleukin-18 stimulates a positive feedback loop during renal obstruction via interleu-kin-18 receptor
    • VanderBrink BA, Asanuma H, Hile K et al. Interleukin-18 stimulates a positive feedback loop during renal obstruction via interleu-kin-18 receptor. J Urol 2011; 186: 1502-1508
    • (2011) J Urol , vol.186 , pp. 1502-1508
    • Vanderbrink, B.A.1    Asanuma, H.2    Hile, K.3
  • 23
    • 84867423244 scopus 로고    scopus 로고
    • Renal IL-18 production is macrophage independent during obstructive injury
    • Franke EI, Vanderbrink BA, Hile K et al. Renal IL-18 production is macrophage independent during obstructive injury. PLoS One 2012; 7: e47417
    • (2012) PLoS One , vol.7
    • Franke, E.I.1    Vanderbrink, B.A.2    Hile, K.3
  • 24
    • 84865820621 scopus 로고    scopus 로고
    • Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia
    • Zhang C, Boini KM, Xia M et al. Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension 2012; 60: 154-162
    • (2012) Hypertension , vol.60 , pp. 154-162
    • Zhang, C.1    Boini, K.M.2    Xia, M.3
  • 25
    • 84862235344 scopus 로고    scopus 로고
    • Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation
    • Wang C, Pan Y, Zhang QY et al. Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation. PLoS One 2012; 7: e38285
    • (2012) PLoS One , vol.7
    • Wang, C.1    Pan, Y.2    Zhang, Q.Y.3
  • 26
    • 79959926939 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation
    • Tsai PY, Ka SM, Chang JM et al. Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation. Free Radic Biol Med 2011; 51: 744-754
    • (2011) Free Radic Biol Med , vol.51 , pp. 744-754
    • Tsai, P.Y.1    Ka, S.M.2    Chang, J.M.3
  • 27
    • 84860681550 scopus 로고    scopus 로고
    • Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats
    • Hu QH, Zhang X, Pan Y et al. Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats. Biochem Pharmacol 2012; 84: 113-125
    • (2012) Biochem Pharmacol , vol.84 , pp. 113-125
    • Hu, Q.H.1    Zhang, X.2    Pan, Y.3
  • 28
    • 2442637919 scopus 로고    scopus 로고
    • Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor i to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis
    • Timoshanko JR, Kitching AR, Inakura Y et al. Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. Am J Pathol 2004; 164: 1967-1977
    • (2004) Am J Pathol , vol.164 , pp. 1967-1977
    • Timoshanko, J.R.1    Kitching, A.R.2    Inakura, Y.3
  • 29
    • 0026011522 scopus 로고
    • Glomerular interleukin 1 production is dependent on macrophage infiltration in anti-GBM glomerulonephritis
    • Tipping PG, Lowe MG, Holdsworth SR. Glomerular interleukin 1 production is dependent on macrophage infiltration in anti-GBM glomerulonephritis. Kidney Int 1991; 39: 103-110
    • (1991) Kidney Int , vol.39 , pp. 103-110
    • Tipping, P.G.1    Lowe, M.G.2    Holdsworth, S.R.3
  • 30
    • 84857819545 scopus 로고    scopus 로고
    • Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome
    • Lacroix-Lamande S, d'Andon MF, Michel E et al. Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome. J Immunol 2012; 188: 2805-2814
    • (2012) J Immunol , vol.188 , pp. 2805-2814
    • Lacroix-Lamande, S.1    D'Andon, M.F.2    Michel, E.3
  • 31
    • 83655163719 scopus 로고    scopus 로고
    • Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy
    • Ribeiro A, Wörnle M, Motamedi N et al. Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy. Kidney Int 2012; 81: 100-111
    • (2012) Kidney Int , vol.81 , pp. 100-111
    • Ribeiro, A.1    Wörnle, M.2    Motamedi, N.3
  • 32
    • 79960714886 scopus 로고    scopus 로고
    • The inflamma-some drives protective Th1 and Th17 cellular responses in disseminated candidiasis
    • van de Veerdonk FL, Joosten LA, Shaw PJ et al. The inflamma-some drives protective Th1 and Th17 cellular responses in disseminated candidiasis. Eur J Immunol 2011; 41: 2260-2268
    • (2011) Eur J Immunol , vol.41 , pp. 2260-2268
    • Van De Veerdonk, F.L.1    Joosten, L.A.2    Shaw, P.J.3
  • 33
    • 73949118676 scopus 로고    scopus 로고
    • Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
    • Iyer SS, Pulskens WB, Sadler JJ et al. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci USA 2009; 106: 20388-20393
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20388-20393
    • Iyer, S.S.1    Pulskens, W.B.2    Sadler, J.J.3
  • 34
    • 84892765811 scopus 로고    scopus 로고
    • Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease
    • (in press)
    • Mulay SR, Evan A, Anders HJ. Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease. Nephrol Dial Transplant 2013; 28: (in press)
    • (2013) Nephrol Dial Transplant , vol.28
    • Mulay, S.R.1    Evan, A.2    Anders, H.J.3
  • 35
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Pétrilli V, Mayor A et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Pétrilli, V.2    Mayor, A.3
  • 36
    • 83355168710 scopus 로고    scopus 로고
    • Pivotal role of toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflamma-some complex in experimental tubule-interstitial nephritis
    • Correa-Costa M, Braga TT, Semedo P et al. Pivotal role of toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflamma-some complex in experimental tubule-interstitial nephritis. PLoS One 2011; 6: e29004
    • (2011) PLoS One , vol.6
    • Correa-Costa, M.1    Braga, T.T.2    Semedo, P.3
  • 37
    • 69949175486 scopus 로고    scopus 로고
    • Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
    • Babelova A, Moreth K, Tsalastra-Greul W et al. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem 2009; 284: 24035-24048
    • (2009) J Biol Chem , vol.284 , pp. 24035-24048
    • Babelova, A.1    Moreth, K.2    Tsalastra-Greul, W.3
  • 38
    • 20144373629 scopus 로고    scopus 로고
    • Tamm-Horsfall glyco-protein links innate immune cell activation with adaptive immunity via a toll-like receptor-4-dependent mechanism
    • Saemann MD, Weichhart T, Zeyda M et al. Tamm-Horsfall glyco-protein links innate immune cell activation with adaptive immunity via a toll-like receptor-4-dependent mechanism. J Clin Invest 2005; 115: 468-475
    • (2005) J Clin Invest , vol.115 , pp. 468-475
    • Saemann, M.D.1    Weichhart, T.2    Zeyda, M.3
  • 39
    • 80555157523 scopus 로고    scopus 로고
    • Cellular pathophysiology of ischemic acute kidney injury
    • Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest 2011; 121: 4210-4221
    • (2011) J Clin Invest , vol.121 , pp. 4210-4221
    • Bonventre, J.V.1    Yang, L.2
  • 40
    • 78650659200 scopus 로고    scopus 로고
    • An inflammasome-in-dependent role for epithelial-expressed Nlrp3 in renal ischemia-re-perfusion injury
    • Shigeoka AA, Mueller JL, Kambo A et al. An inflammasome-in-dependent role for epithelial-expressed Nlrp3 in renal ischemia-re-perfusion injury. J Immunol 2010; 185: 6277-6285
    • (2010) J Immunol , vol.185 , pp. 6277-6285
    • Shigeoka, A.A.1    Mueller, J.L.2    Kambo, A.3
  • 41
    • 0031944498 scopus 로고    scopus 로고
    • Role of IL-1 in renal ischemic re-perfusion injury
    • Haq M, Norman J, Saba SR et al. Role of IL-1 in renal ischemic re-perfusion injury. J Am Soc Nephrol 1998; 9: 614-619
    • (1998) J Am Soc Nephrol , vol.9 , pp. 614-619
    • Haq, M.1    Norman, J.2    Saba, S.R.3
  • 42
    • 57149102957 scopus 로고    scopus 로고
    • IL-18 contributes to renal damage after ischemia-reperfusion
    • Wu H, Craft ML, Wang P et al. IL-18 contributes to renal damage after ischemia-reperfusion. J Am Soc Nephrol 2008; 19: 2331-2341
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2331-2341
    • Wu, H.1    Craft, M.L.2    Wang, P.3
  • 43
    • 0033136706 scopus 로고    scopus 로고
    • Ischemia/reperfusion-induced IFN-gamma up-regulation: Involvement of IL-12 and IL-18
    • Daemen MA, van't Veer C, Wolfs TG et al. Ischemia/reperfusion-induced IFN-gamma up-regulation: involvement of IL-12 and IL-18. J Immunol 1999; 162: 5506-5510
    • (1999) J Immunol , vol.162 , pp. 5506-5510
    • Daemen, M.A.1    Van'T Veer, C.2    Wolfs, T.G.3
  • 44
    • 77957887259 scopus 로고    scopus 로고
    • The NLRP3 inflamma-some promotes renal inflammation and contributes to CKD
    • Vilaysane A, Chun J, Seamone ME et al. The NLRP3 inflamma-some promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 2010; 21: 1732-1744
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1732-1744
    • Vilaysane, A.1    Chun, J.2    Seamone, M.E.3
  • 45
    • 68949207806 scopus 로고    scopus 로고
    • IL-18 neutralization ameliorates obstruction-induced epithelial- mesenchymal transition and renal fibrosis
    • Bani-Hani AH, Leslie JA, Asanuma H et al. IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int 2009; 76: 500-511
    • (2009) Kidney Int , vol.76 , pp. 500-511
    • Bani-Hani, A.H.1    Leslie, J.A.2    Asanuma, H.3
  • 46
    • 0035061819 scopus 로고    scopus 로고
    • Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro
    • Fan JM, Huang XR, Ng YY et al. Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro. Am J Kidney Dis 2001; 37: 820-831
    • (2001) Am J Kidney Dis , vol.37 , pp. 820-831
    • Fan, J.M.1    Huang, X.R.2    Ng, Y.Y.3
  • 47
    • 84872737232 scopus 로고    scopus 로고
    • Inflammasome-Independent NLRP3 augments TGF-beta signaling in kidney epithelium
    • Wang W, Wang X, Chun J et al. Inflammasome-Independent NLRP3 augments TGF-beta signaling in kidney epithelium. J Immunol 2013; 190: 1239-1249
    • (2013) J Immunol , vol.190 , pp. 1239-1249
    • Wang, W.1    Wang, X.2    Chun, J.3
  • 48
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119: 1420-1428
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 49
    • 79551521517 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy?
    • Kriz W, Kaissling B, Le Hir M. Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?. J Clin Invest 2011; 121: 468-474
    • (2011) J Clin Invest , vol.121 , pp. 468-474
    • Kriz, W.1    Kaissling, B.2    Le Hir, M.3
  • 50
    • 84892694402 scopus 로고    scopus 로고
    • The inflammasome-related molecules NLRP3 and ASC suppress lupus nephritis of C57Bl/6lpr/lpr mice
    • Congress Abstract MO055
    • Lech M, Lorenz G, Kulkarni O et al. The inflammasome-related molecules NLRP3 and ASC suppress lupus nephritis of C57Bl/6lpr/lpr mice. Nephrol Dial Transplant 2013; 28: p. Congress Abstract MO055
    • (2013) Nephrol Dial Transplant , vol.28
    • Lech, M.1    Lorenz, G.2    Kulkarni, O.3
  • 51
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • Allen IC, Scull MA, Moore CB et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009; 30: 556-565
    • (2009) Immunity , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3
  • 52
    • 77749270973 scopus 로고    scopus 로고
    • Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
    • Harder J, Franchi L, Muñoz-Planillo R et al. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 2009; 183: 5823-5829
    • (2009) J Immunol , vol.183 , pp. 5823-5829
    • Harder, J.1    Franchi, L.2    Muñoz-Planillo, R.3
  • 53
    • 70449360107 scopus 로고    scopus 로고
    • Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
    • Craven RR, Gao X, Allen IC et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One 2009; 4: e7446
    • (2009) PLoS One , vol.4
    • Craven, R.R.1    Gao, X.2    Allen, I.C.3
  • 54
    • 32944470765 scopus 로고    scopus 로고
    • Cryopyrin activates the inflammasome in response to toxins and ATP
    • Mariathasan S, Weiss DS, Newton K et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006; 440: 228-232
    • (2006) Nature , vol.440 , pp. 228-232
    • Mariathasan, S.1    Weiss, D.S.2    Newton, K.3
  • 55
    • 84864849535 scopus 로고    scopus 로고
    • Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4
    • Allam R, Scherbaum CR, Darisipudi MN et al. Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. J Am Soc Nephrol 2012; 23: 1375-1388
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1375-1388
    • Allam, R.1    Scherbaum, C.R.2    Darisipudi, M.N.3
  • 56
    • 84861162164 scopus 로고    scopus 로고
    • U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes
    • Shin MS, Kang Y, Lee N et al. U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes. J Immunol 2012; 188: 4769-4775
    • (2012) J Immunol , vol.188 , pp. 4769-4775
    • Shin, M.S.1    Kang, Y.2    Lee, N.3
  • 57
    • 84873550853 scopus 로고    scopus 로고
    • Self double-stranded (ds)DNA induces IL-1beta production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies
    • Shin MS, Kang Y, Lee N et al. Self double-stranded (ds)DNA induces IL-1beta production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies. J Immunol 2013; 190: 1407-1415
    • (2013) J Immunol , vol.190 , pp. 1407-1415
    • Shin, M.S.1    Kang, Y.2    Lee, N.3
  • 58
    • 84870514546 scopus 로고    scopus 로고
    • ATP Release and purinergic signaling: A common pathway for particle-mediated inflamma-some activation
    • Riteau N, Baron L, Villeret B et al. ATP Release and purinergic signaling: a common pathway for particle-mediated inflamma-some activation. Cell Death Dis 2012; 3: e403
    • (2012) Cell Death Dis , vol.3
    • Riteau, N.1    Baron, L.2    Villeret, B.3
  • 59
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Pétrilli V, Van Bruggen R et al. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008; 320: 674-677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Pétrilli, V.2    Van Bruggen, R.3
  • 60
    • 47849132947 scopus 로고    scopus 로고
    • The Nalp3 inflammasome is essential for the development of silicosis
    • Cassel SL, Eisenbarth SC, Iyer SS et al. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci USA, 2008; 105: 9035-9040
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9035-9040
    • Cassel, S.L.1    Eisenbarth, S.C.2    Iyer, S.S.3
  • 61
    • 47849085872 scopus 로고    scopus 로고
    • The NALP3 inflamma-some is involved in the innate immune response to amyloid-beta
    • Halle A, Hornung V, Petzold GC et al. The NALP3 inflamma-some is involved in the innate immune response to amyloid-beta. Nat Immunol 2008; 9: 857-865
    • (2008) Nat Immunol , vol.9 , pp. 857-865
    • Halle, A.1    Hornung, V.2    Petzold, G.C.3
  • 62
    • 70049101754 scopus 로고    scopus 로고
    • Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
    • Shio MT, Eisenbarth SC, Savaria M et al. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog 2009; 5: e1000559
    • (2009) PLoS Pathog , vol.5
    • Shio, M.T.1    Eisenbarth, S.C.2    Savaria, M.3
  • 63
    • 67649831360 scopus 로고    scopus 로고
    • NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluro-nan, an endogenous trigger of inflammation in response to injury
    • Yamasaki K, Muto J, Taylor KR et al. NLRP3/cryopyrin Is necessary for interleukin-1beta (IL-1beta) release in response to hyaluro-nan, an endogenous trigger of inflammation in response to injury. J Biol Chem 2009; 284: 12762-12771
    • (2009) J Biol Chem , vol.284 , pp. 12762-12771
    • Yamasaki, K.1    Muto, J.2    Taylor, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.