-
2
-
-
75149166672
-
Metabolic effects of fructose and the worldwide increase in obesity
-
L. Tappy, and K.A. Le Metabolic effects of fructose and the worldwide increase in obesity Physiol Rev 90 2010 23 46
-
(2010)
Physiol Rev
, vol.90
, pp. 23-46
-
-
Tappy, L.1
Le, K.A.2
-
3
-
-
70349647191
-
Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: Renal organic ion transporter involvement
-
Q.H. Hu, C. Wang, J.M. Li, D.M. Zhang, and L.D. Kong Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement Am J Physiol Renal Physiol 297 2009 1080 1091
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. 1080-1091
-
-
Hu, Q.H.1
Wang, C.2
Li, J.M.3
Zhang, D.M.4
Kong, L.D.5
-
4
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
F. Martinon, V. Petrilli, A. Mayor, A. Tardivel, and J. Tschopp Gout-associated uric acid crystals activate the NALP3 inflammasome Nature 440 2006 237 241
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
5
-
-
74549184092
-
The NLRP3 inflammasome: A sensor for metabolic danger
-
K. Schroder, R. Zhou, and J. Tschopp The NLRP3 inflammasome: a sensor for metabolic danger Science 327 2010 296 300
-
(2010)
Science
, vol.327
, pp. 296-300
-
-
Schroder, K.1
Zhou, R.2
Tschopp, J.3
-
6
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
L. Agostini, F. Martinon, K. Burns, M.F. McDermott, P.N. Hawkins, and J. Tschopp NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder Immunity 20 2004 319 325
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
7
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
A. Vilaysane, J. Chun, M.E. Seamone, W. Wang, R. Chin, and S. Hirota The NLRP3 inflammasome promotes renal inflammation and contributes to CKD J Am Soc Nephrol 21 2010 1732 1744
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1732-1744
-
-
Vilaysane, A.1
Chun, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, S.6
-
8
-
-
61349127856
-
Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular risk
-
F. Bandukwala, M. Huang, J.S. Zaltzman, M.M. Nash, and G.V. Prasad Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular risk Am J Cardiol 103 2009 867 871
-
(2009)
Am J Cardiol
, vol.103
, pp. 867-871
-
-
Bandukwala, F.1
Huang, M.2
Zaltzman, J.S.3
Nash, M.M.4
Prasad, G.V.5
-
9
-
-
35148862908
-
Fructose, but not dextrose, accelerates the progression of chronic kidney disease
-
M.S. Gersch, W. Mu, P. Cirillo, S. Reungjui, L. Zhang, and C. Roncal Fructose, but not dextrose, accelerates the progression of chronic kidney disease Am J Physiol Renal Physiol 293 2007 1256 1261
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. 1256-1261
-
-
Gersch, M.S.1
Mu, W.2
Cirillo, P.3
Reungjui, S.4
Zhang, L.5
Roncal, C.6
-
10
-
-
78249286865
-
Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1beta production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis
-
L.A. Joosten, M.G. Netea, E. Mylona, M.I. Koenders, R.K. Malireddi, and M. Oosting Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1beta production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis Arthritis Rheum 62 2010 3237 3248
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3237-3248
-
-
Joosten, L.A.1
Netea, M.G.2
Mylona, E.3
Koenders, M.I.4
Malireddi, R.K.5
Oosting, M.6
-
11
-
-
78650796942
-
Role of PPARalpha and its agonist in renal diseases
-
C.F. Cheng, H.H. Chen, and H. Lin Role of PPARalpha and its agonist in renal diseases PPAR Res 2010 2010 345098
-
(2010)
PPAR Res
, vol.2010
, pp. 345098
-
-
Cheng, C.F.1
Chen, H.H.2
Lin, H.3
-
12
-
-
28944432295
-
PPAR-alpha expression inversely correlates with inflammatory cytokines IL-1beta and TNF-alpha in aging rats
-
D.S. Gelinas, and J. McLaurin PPAR-alpha expression inversely correlates with inflammatory cytokines IL-1beta and TNF-alpha in aging rats Neurochem Res 30 2005 1369 1375
-
(2005)
Neurochem Res
, vol.30
, pp. 1369-1375
-
-
Gelinas, D.S.1
McLaurin, J.2
-
13
-
-
0030827807
-
Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes
-
J.H. Parmentier, H. Schohn, M. Bronner, L. Ferrari, A.M. Batt, and M. Dauca Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes Biochem Pharmacol 54 1997 889 898
-
(1997)
Biochem Pharmacol
, vol.54
, pp. 889-898
-
-
Parmentier, J.H.1
Schohn, H.2
Bronner, M.3
Ferrari, L.4
Batt, A.M.5
Dauca, M.6
-
14
-
-
0033613959
-
Cross-talk between janus kinase-signal transducer and activator of transcription (JAK-STAT) and peroxisome proliferator-activated receptor-alpha (PPARalpha) signaling pathways. Growth hormone inhibition of pparalpha transcriptional activity mediated by stat5b
-
Y.C. Zhou, and D.J. Waxman Cross-talk between janus kinase-signal transducer and activator of transcription (JAK-STAT) and peroxisome proliferator-activated receptor-alpha (PPARalpha) signaling pathways. Growth hormone inhibition of pparalpha transcriptional activity mediated by stat5b J Biol Chem 274 1999 2672 2681
-
(1999)
J Biol Chem
, vol.274
, pp. 2672-2681
-
-
Zhou, Y.C.1
Waxman, D.J.2
-
15
-
-
0034640508
-
Activation of downstream signals by the long form of the leptin receptor
-
A.S. Banks, S.M. Davis, S.H. Bates, and M.G. Myers Jr. Activation of downstream signals by the long form of the leptin receptor J Biol Chem 275 2000 14563 14572
-
(2000)
J Biol Chem
, vol.275
, pp. 14563-14572
-
-
Banks, A.S.1
Davis, S.M.2
Bates, S.H.3
Myers, Jr.M.G.4
-
16
-
-
2942628012
-
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms
-
K. Ueki, T. Kondo, and C.R. Kahn Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms Mol Cell Biol 24 2004 5434 5446
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5434-5446
-
-
Ueki, K.1
Kondo, T.2
Kahn, C.R.3
-
17
-
-
33845873659
-
Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
-
J. Jager, T. Gremeaux, M. Cormont, Y. Le Marchand-Brustel, and J.F. Tanti Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression Endocrinology 148 2007 241 251
-
(2007)
Endocrinology
, vol.148
, pp. 241-251
-
-
Jager, J.1
Gremeaux, T.2
Cormont, M.3
Le Marchand-Brustel, Y.4
Tanti, J.F.5
-
18
-
-
34247511618
-
TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - Effects on leptin and insulin signaling pathways
-
T. Romanatto, M. Cesquini, M.E. Amaral, E.A. Roman, J.C. Moraes, and M.A. Torsoni TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - effects on leptin and insulin signaling pathways Peptides 28 2007 1050 1058
-
(2007)
Peptides
, vol.28
, pp. 1050-1058
-
-
Romanatto, T.1
Cesquini, M.2
Amaral, M.E.3
Roman, E.A.4
Moraes, J.C.5
Torsoni, M.A.6
-
19
-
-
7044274089
-
Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice
-
T. Ide, M. Tsunoda, T. Mochizuki, and K. Murakami Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice Med Sci Monit 10 2004 388 395
-
(2004)
Med Sci Monit
, vol.10
, pp. 388-395
-
-
Ide, T.1
Tsunoda, M.2
Mochizuki, T.3
Murakami, K.4
-
20
-
-
56149125083
-
Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism
-
L. Vila, N. Roglans, M. Alegret, R.M. Sanchez, M. Vazquez-Carrera, and J.C. Laguna Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism Hepatology 48 2008 1506 1516
-
(2008)
Hepatology
, vol.48
, pp. 1506-1516
-
-
Vila, L.1
Roglans, N.2
Alegret, M.3
Sanchez, R.M.4
Vazquez-Carrera, M.5
Laguna, J.C.6
-
21
-
-
76049099485
-
Role of central leptin signaling in renal macrophage infiltration
-
M. Tanaka, T. Suganami, S. Sugita, Y. Shimoda, M. Kasahara, and S. Aoe Role of central leptin signaling in renal macrophage infiltration Endocrine J 57 2010 61 72
-
(2010)
Endocrine J
, vol.57
, pp. 61-72
-
-
Tanaka, M.1
Suganami, T.2
Sugita, S.3
Shimoda, Y.4
Kasahara, M.5
Aoe, S.6
-
22
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
B. Vandanmagsar, Y.H. Youm, A. Ravussin, J.E. Galgani, K. Stadler, and R.L. Mynatt The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance Nat Med 17 2011 179 188
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
-
23
-
-
70350366890
-
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis
-
A.A. Abdul-Sater, E. Koo, G. Hacker, and D.M. Ojcius Inflammasome- dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis J Biol Chem 284 2009 26789 26796
-
(2009)
J Biol Chem
, vol.284
, pp. 26789-26796
-
-
Abdul-Sater, A.A.1
Koo, E.2
Hacker, G.3
Ojcius, D.M.4
-
24
-
-
77951427605
-
Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats
-
J.M. Li, Y.C. Li, L.D. Kong, and Q.H. Hu Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats Hepatology 51 2010 1555 1566
-
(2010)
Hepatology
, vol.51
, pp. 1555-1566
-
-
Li, J.M.1
Li, Y.C.2
Kong, L.D.3
Hu, Q.H.4
-
25
-
-
78650988141
-
Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta
-
S.A. Nicholas, V.V. Bubnov, I.M. Yasinska, and V.V. Sumbayev Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta Cell Mol Life Sci 68 2011 151 158
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 151-158
-
-
Nicholas, S.A.1
Bubnov, V.V.2
Yasinska, I.M.3
Sumbayev, V.V.4
-
26
-
-
74049105256
-
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
-
J.W. Griffith, T. Sun, M.T. McIntosh, and R. Bucala Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid J Immunol 183 2009 5208 5220
-
(2009)
J Immunol
, vol.183
, pp. 5208-5220
-
-
Griffith, J.W.1
Sun, T.2
McIntosh, M.T.3
Bucala, R.4
-
27
-
-
0020852058
-
Effects on liver and serum lipids of dietary supplements of methionine and excess lysine given to previously-starved rats
-
Y. Aoyama, K. Sakaida, A. Yoshida, and K. Ashida Effects on liver and serum lipids of dietary supplements of methionine and excess lysine given to previously-starved rats Br J Nutr 50 1983 627 636
-
(1983)
Br J Nutr
, vol.50
, pp. 627-636
-
-
Aoyama, Y.1
Sakaida, K.2
Yoshida, A.3
Ashida, K.4
-
28
-
-
0036732947
-
Early treatment with allopurinol in familial juvenile hyerpuricaemic nephropathy (FJHN) ameliorates the long-term progression of renal disease
-
L.D. Fairbanks, J.S. Cameron, G. Venkat-Raman, S.P. Rigden, L. Rees, and T.H.W. Van Early treatment with allopurinol in familial juvenile hyerpuricaemic nephropathy (FJHN) ameliorates the long-term progression of renal disease QJM 95 2002 597 607
-
(2002)
QJM
, vol.95
, pp. 597-607
-
-
Fairbanks, L.D.1
Cameron, J.S.2
Venkat-Raman, G.3
Rigden, S.P.4
Rees, L.5
Van, T.H.W.6
-
29
-
-
73749083955
-
Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: A double-blinded, placebo-controlled cross-over study
-
S. Egert, A. Bosy-Westphal, J. Seiberl, C. Kurbitz, U. Settler, and S. Plachta-Danielzik Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study Br J Nutr 102 2009 1065 1074
-
(2009)
Br J Nutr
, vol.102
, pp. 1065-1074
-
-
Egert, S.1
Bosy-Westphal, A.2
Seiberl, J.3
Kurbitz, C.4
Settler, U.5
Plachta-Danielzik, S.6
-
30
-
-
2942532733
-
Effects of biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver
-
J.X. Zhu, Y. Wang, L.D. Kong, C. Yang, and X. Zhang Effects of biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver J Ethnopharmacol 93 2004 133 140
-
(2004)
J Ethnopharmacol
, vol.93
, pp. 133-140
-
-
Zhu, J.X.1
Wang, Y.2
Kong, L.D.3
Yang, C.4
Zhang, X.5
-
31
-
-
78449307046
-
Protective effect of rutin on the ischemia/reperfusion induced damage in rat kidney
-
A. Korkmaz, and D. Kolankaya Protective effect of rutin on the ischemia/reperfusion induced damage in rat kidney J Surg Res 164 2010 309 315
-
(2010)
J Surg Res
, vol.164
, pp. 309-315
-
-
Korkmaz, A.1
Kolankaya, D.2
-
32
-
-
80054900854
-
Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity
-
P.D. Sanchez-Gonzalez, F.J. Lopez-Hernandez, F. Perez-Barriocanal, A.I. Morales, and J.M. Lopez-Novoa Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity Nephrol Dial Transplant 6 2011 3484 3495
-
(2011)
Nephrol Dial Transplant
, vol.6
, pp. 3484-3495
-
-
Sanchez-Gonzalez, P.D.1
Lopez-Hernandez, F.J.2
Perez-Barriocanal, F.3
Morales, A.I.4
Lopez-Novoa, J.M.5
-
33
-
-
59949086782
-
Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats
-
I.T. Abdel-Raheem, A.A. Abdel-Ghany, and G.A. Mohamed Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats Biol Pharm Bull. 32 2009 61 67
-
(2009)
Biol Pharm Bull.
, vol.32
, pp. 61-67
-
-
Abdel-Raheem, I.T.1
Abdel-Ghany, A.A.2
Mohamed, G.A.3
-
34
-
-
33747074105
-
The influence of rutin on the extracellular matrix in streptozotocin-induced diabetic rat kidney
-
N. Kamalakkannan, and P. Stanely Mainzen Prince The influence of rutin on the extracellular matrix in streptozotocin-induced diabetic rat kidney J Pharm Pharmacol 58 2006 1091 1098
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 1091-1098
-
-
Kamalakkannan, N.1
Stanely Mainzen Prince, P.2
-
35
-
-
79960843843
-
Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NF(B, TNF-α and caspase-3 expression in wistar rats
-
W. Arjumand, A. Seth, and S. Sultana Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NF(B, TNF-α and caspase-3 expression in wistar rats Food Chem Toxicol 49 2011 2013 2021
-
(2011)
Food Chem Toxicol
, vol.49
, pp. 2013-2021
-
-
Arjumand, W.1
Seth, A.2
Sultana, S.3
-
36
-
-
18444396626
-
Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats
-
M. Minami, A. Ishiyama, M. Takagi, M. Omata, and K. Atarashi Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats Blood Press 14 2005 120 125
-
(2005)
Blood Press
, vol.14
, pp. 120-125
-
-
Minami, M.1
Ishiyama, A.2
Takagi, M.3
Omata, M.4
Atarashi, K.5
-
37
-
-
23244464983
-
IL-1 beta induces IL-6 expression in human orbital fibroblasts: Identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy
-
B. Chen, S. Tsui, and T.J. Smith IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy J Immunol 175 2005 1310 1319
-
(2005)
J Immunol
, vol.175
, pp. 1310-1319
-
-
Chen, B.1
Tsui, S.2
Smith, T.J.3
-
38
-
-
12144289387
-
Interleukin-1 beta (IL-1beta) induces tumor necrosis factor alpha (TNF-alpha) expression on mouse myeloid multipotent cell line 32D cl3 and inhibits their proliferation
-
E. Ledesma, I. Martinez, Y. Cordova, M. Rodriguez-Sosa, A. Monroy, and L. Mora Interleukin-1 beta (IL-1beta) induces tumor necrosis factor alpha (TNF-alpha) expression on mouse myeloid multipotent cell line 32D cl3 and inhibits their proliferation Cytokine 26 2004 66 72
-
(2004)
Cytokine
, vol.26
, pp. 66-72
-
-
Ledesma, E.1
Martinez, I.2
Cordova, Y.3
Rodriguez-Sosa, M.4
Monroy, A.5
Mora, L.6
-
39
-
-
0033788437
-
Interleukin-18 induces production of proinflammatory cytokines in mice: No intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1beta
-
M.G. Netea, B.J. Kullberg, I. Verschueren, and J.W. Van Der Meer Interleukin-18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1beta Eur J Immunol 30 2000 3057 3060
-
(2000)
Eur J Immunol
, vol.30
, pp. 3057-3060
-
-
Netea, M.G.1
Kullberg, B.J.2
Verschueren, I.3
Van Der Meer, J.W.4
-
40
-
-
0032767691
-
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter
-
X. Wu, W. Huang, P.D. Prasad, P. Seth, D.P. Rajan, and F.H. Leibach Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter J Pharmacol Exp Ther 290 1999 1482 1492
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 1482-1492
-
-
Wu, X.1
Huang, W.2
Prasad, P.D.3
Seth, P.4
Rajan, D.P.5
Leibach, F.H.6
-
41
-
-
0024246260
-
Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts
-
W.R. Treem, C.A. Stanley, D.N. Finegold, D.E. Hale, and P.M. Coates Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts N Engl J Med 319 1988 1331 1336
-
(1988)
N Engl J Med
, vol.319
, pp. 1331-1336
-
-
Treem, W.R.1
Stanley, C.A.2
Finegold, D.N.3
Hale, D.E.4
Coates, P.M.5
-
42
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
P. Duewell, H. Kono, K.J. Rayner, C.M. Sirois, G. Vladimer, and F.G. Bauernfeind NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals Nature 464 2010 1357 1361
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
-
43
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation
-
K. Rajamaki, J. Lappalainen, K. Oorni, E. Valimaki, S. Matikainen, and P.T. Kovanen Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation PLoS One 5 2010 11765
-
(2010)
PLoS One
, vol.5
, pp. 11765
-
-
Rajamaki, K.1
Lappalainen, J.2
Oorni, K.3
Valimaki, E.4
Matikainen, S.5
Kovanen, P.T.6
-
44
-
-
79957773993
-
The inflammasomes in kidney disease
-
H.J. Anders, and D.A. Muruve The inflammasomes in kidney disease J Am Soc Nephrol 22 2011 1007 1018
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1007-1018
-
-
Anders, H.J.1
Muruve, D.A.2
-
45
-
-
80055069956
-
Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome
-
J.M. Busillo, K.M. Azzam, and J.A. Cidlowski Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome J Biol Chem 286 2011 38703 38713
-
(2011)
J Biol Chem
, vol.286
, pp. 38703-38713
-
-
Busillo, J.M.1
Azzam, K.M.2
Cidlowski, J.A.3
-
46
-
-
77952146703
-
Correlation of tumor necrosis factor alpha and interleukin 6 with hypertensive renal damage
-
X. Yu, Z. Yang, and M. Yu Correlation of tumor necrosis factor alpha and interleukin 6 with hypertensive renal damage Ren Fail 32 2010 475 479
-
(2010)
Ren Fail
, vol.32
, pp. 475-479
-
-
Yu, X.1
Yang, Z.2
Yu, M.3
-
48
-
-
82955188694
-
The effects of inflammation on lipid accumulation in the kidneys of children with primary nephrotic syndrome
-
G. Zhang, Q. Li, L. Wang, Y. Chen, W. Zhang, and H. Yang The effects of inflammation on lipid accumulation in the kidneys of children with primary nephrotic syndrome Inflammation 34 2011 645 652
-
(2011)
Inflammation
, vol.34
, pp. 645-652
-
-
Zhang, G.1
Li, Q.2
Wang, L.3
Chen, Y.4
Zhang, W.5
Yang, H.6
-
49
-
-
60549100329
-
PPAR{alpha} attenuates the proinflammatory response in activated mesangial cells
-
K. Kono, Y. Kamijo, K. Hora, K. Takahashi, M. Higuchi, and K. Kiyosawa PPAR{alpha} attenuates the proinflammatory response in activated mesangial cells Am J Physiol Renal Physiol 296 2009 328 336
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, pp. 328-336
-
-
Kono, K.1
Kamijo, Y.2
Hora, K.3
Takahashi, K.4
Higuchi, M.5
Kiyosawa, K.6
-
50
-
-
33845999602
-
Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate
-
Y. Kamijo, K. Hora, T. Nakajima, K. Kono, K. Takahashi, and Y. Ito Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate J Am Soc Nephrol 18 2007 176 188
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 176-188
-
-
Kamijo, Y.1
Hora, K.2
Nakajima, T.3
Kono, K.4
Takahashi, K.5
Ito, Y.6
-
51
-
-
38049113001
-
Renoprotective action of l-carnitine in fructose-induced metabolic syndrome
-
P. Rajasekar, P. Viswanathan, and C.V. Anuradha Renoprotective action of l-carnitine in fructose-induced metabolic syndrome Diabetes Obes Metab 10 2008 171 180
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 171-180
-
-
Rajasekar, P.1
Viswanathan, P.2
Anuradha, C.V.3
-
52
-
-
65349172318
-
Histopathological and scintigraphic comparisons of the protective effects of l-carnitine and amifostine against radiation-induced late renal toxicity in rats
-
M. Caloglu, V. Yurut-Caloglu, G. Durmus-Altun, F. Oz-Puyan, F. Ustun, and R. Cosar-Alas Histopathological and scintigraphic comparisons of the protective effects of l-carnitine and amifostine against radiation-induced late renal toxicity in rats Clin Exp Pharmacol Physiol 36 2009 523 530
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, pp. 523-530
-
-
Caloglu, M.1
Yurut-Caloglu, V.2
Durmus-Altun, G.3
Oz-Puyan, F.4
Ustun, F.5
Cosar-Alas, R.6
-
53
-
-
15744394674
-
Fructose, insulin resistance, and metabolic dyslipidemia
-
H. Basciano, L. Federico, and K. Adeli Fructose, insulin resistance, and metabolic dyslipidemia Nutr Metab (Lond) 2 2005 5
-
(2005)
Nutr Metab (Lond)
, vol.2
, pp. 5
-
-
Basciano, H.1
Federico, L.2
Adeli, K.3
-
54
-
-
58949094416
-
Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A
-
R. Rodriguez-Calvo, E. Barroso, L. Serrano, T. Coll, R.M. Sanchez, and M. Merlos Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A Hepatology 49 2009 106 115
-
(2009)
Hepatology
, vol.49
, pp. 106-115
-
-
Rodriguez-Calvo, R.1
Barroso, E.2
Serrano, L.3
Coll, T.4
Sanchez, R.M.5
Merlos, M.6
-
55
-
-
77956650662
-
High-calorie diet partially ameliorates dysregulation of intrarenal lipid metabolism in remnant kidney
-
H.J. Kim, J. Yuan, K. Norris, and N.D. Vaziri High-calorie diet partially ameliorates dysregulation of intrarenal lipid metabolism in remnant kidney J Nutr Biochem 10 2010 999 1007
-
(2010)
J Nutr Biochem
, vol.10
, pp. 999-1007
-
-
Kim, H.J.1
Yuan, J.2
Norris, K.3
Vaziri, N.D.4
-
56
-
-
79953317030
-
Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice
-
M. Kobori, S. Masumoto, Y. Akimoto, and H. Oike Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice Mol Nutr Food Res 55 2011 530 540
-
(2011)
Mol Nutr Food Res
, vol.55
, pp. 530-540
-
-
Kobori, M.1
Masumoto, S.2
Akimoto, Y.3
Oike, H.4
-
57
-
-
79952765671
-
Mulberry water extracts possess an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote lipolysis
-
C.H. Peng, L.K. Liu, C.M. Chuang, C.C. Chyau, C.N. Huang, and C.J. Wang Mulberry water extracts possess an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote lipolysis J Agric Food Chem 59 2011 2663 2671
-
(2011)
J Agric Food Chem
, vol.59
, pp. 2663-2671
-
-
Peng, C.H.1
Liu, L.K.2
Chuang, C.M.3
Chyau, C.C.4
Huang, C.N.5
Wang, C.J.6
-
58
-
-
77955309041
-
Pro-inflammatory cytokines induce suppressor of cytokine signaling-3 in human periodontal ligament cells
-
A. Fukushima, H. Kajiya, T. Izumi, C. Shigeyama, K. Okabe, and H. Anan Pro-inflammatory cytokines induce suppressor of cytokine signaling-3 in human periodontal ligament cells J Endod 36 2010 1004 1008
-
(2010)
J Endod
, vol.36
, pp. 1004-1008
-
-
Fukushima, A.1
Kajiya, H.2
Izumi, T.3
Shigeyama, C.4
Okabe, K.5
Anan, H.6
-
59
-
-
0037844877
-
JAK2/STAT3, not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes
-
X. Yu, R.H. Kennedy, and S.J. Liu JAK2/STAT3, not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes J Biol Chem 278 2003 16304 16309
-
(2003)
J Biol Chem
, vol.278
, pp. 16304-16309
-
-
Yu, X.1
Kennedy, R.H.2
Liu, S.J.3
-
60
-
-
80052290747
-
N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats
-
T. Wang, S. Qiao, S. Lei, Y. Liu, K.F. Ng, and A. Xu N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats PLoS One 6 2011 e23967
-
(2011)
PLoS One
, vol.6
, pp. 23967
-
-
Wang, T.1
Qiao, S.2
Lei, S.3
Liu, Y.4
Ng, K.F.5
Xu, A.6
-
61
-
-
27744481080
-
Endothelin-1 activation of JAK2 in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species
-
A.K. Banes-Berceli, S. Ogobi, A. Tawfik, B. Patel, A. Shirley, and D.M. Pollock Endothelin-1 activation of JAK2 in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species Vascul Pharmacol 43 2005 310 319
-
(2005)
Vascul Pharmacol
, vol.43
, pp. 310-319
-
-
Banes-Berceli, A.K.1
Ogobi, S.2
Tawfik, A.3
Patel, B.4
Shirley, A.5
Pollock, D.M.6
-
62
-
-
64549087585
-
Blockade of oxidized LDL-triggered endothelial apoptosis by quercetin and rutin through differential signaling pathways involving JAK2
-
J.S. Choi, S.W. Kang, J. Li, J.L. Kim, J.Y. Bae, and D.S. Kim Blockade of oxidized LDL-triggered endothelial apoptosis by quercetin and rutin through differential signaling pathways involving JAK2 J Agric Food Chem 57 2009 2079 2086
-
(2009)
J Agric Food Chem
, vol.57
, pp. 2079-2086
-
-
Choi, J.S.1
Kang, S.W.2
Li, J.3
Kim, J.L.4
Bae, J.Y.5
Kim, D.S.6
-
63
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
H. Wen, D. Gris, Y. Lei, S. Jha, L. Zhang, and M.T. Huang Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling Nat Immunol 12 2011 408 415
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
-
64
-
-
2342428466
-
Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner
-
C. de Alvaro, T. Teruel, R. Hernandez, and M. Lorenzo Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner J Biol Chem 279 2004 17070 17078
-
(2004)
J Biol Chem
, vol.279
, pp. 17070-17078
-
-
De Alvaro, C.1
Teruel, T.2
Hernandez, R.3
Lorenzo, M.4
-
65
-
-
77953148018
-
Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells
-
A. Natalicchio, F. De Stefano, M.R. Orlando, M. Melchiorre, A. Leonardini, and A. Cignarelli Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells Endocrinology 151 2010 2019 2029
-
(2010)
Endocrinology
, vol.151
, pp. 2019-2029
-
-
Natalicchio, A.1
De Stefano, F.2
Orlando, M.R.3
Melchiorre, M.4
Leonardini, A.5
Cignarelli, A.6
-
66
-
-
37249093922
-
SOCS proteins causing trouble in insulin action
-
P. Lebrun, and E. Van Obberghen SOCS proteins causing trouble in insulin action Acta Physiol (Oxf) 192 2008 29 36
-
(2008)
Acta Physiol (Oxf)
, vol.192
, pp. 29-36
-
-
Lebrun, P.1
Van Obberghen, E.2
-
67
-
-
78449309728
-
SOCS3 inhibits insulin signaling in porcine primary adipocytes
-
S.J. Yang, C.Q. Xu, J.W. Wu, and G.S. Yang SOCS3 inhibits insulin signaling in porcine primary adipocytes Mol Cell Biochem 345 2010 45 52
-
(2010)
Mol Cell Biochem
, vol.345
, pp. 45-52
-
-
Yang, S.J.1
Xu, C.Q.2
Wu, J.W.3
Yang, G.S.4
-
68
-
-
59949104510
-
Peroxisome proliferator-activated receptor-alpha modulates insulin gene transcription factors and inflammation in adipose tissues in mice
-
A. Yessoufou, J.M. Ategbo, E. Attakpa, A. Hichami, K. Moutairou, and K.L. Dramane Peroxisome proliferator-activated receptor-alpha modulates insulin gene transcription factors and inflammation in adipose tissues in mice Mol Cell Biochem 323 2009 101 111
-
(2009)
Mol Cell Biochem
, vol.323
, pp. 101-111
-
-
Yessoufou, A.1
Ategbo, J.M.2
Attakpa, E.3
Hichami, A.4
Moutairou, K.5
Dramane, K.L.6
-
69
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
A.R. Saltiel, and C.R. Kahn Insulin signalling and the regulation of glucose and lipid metabolism Nature 414 2001 799 806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
70
-
-
78651290317
-
Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes
-
C.C. Chuang, K. Martinez, G. Xie, A. Kennedy, A. Bumrungpert, and A. Overman Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes Am J Clin Nutr 92 2010 1511 1521
-
(2010)
Am J Clin Nutr
, vol.92
, pp. 1511-1521
-
-
Chuang, C.C.1
Martinez, K.2
Xie, G.3
Kennedy, A.4
Bumrungpert, A.5
Overman, A.6
-
71
-
-
80052703398
-
Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media
-
A. Overman, C.C. Chuang, and M. McIntosh Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage- conditioned media Int J Obes (Lond) 35 2011 1165 1172
-
(2011)
Int J Obes (Lond)
, vol.35
, pp. 1165-1172
-
-
Overman, A.1
Chuang, C.C.2
McIntosh, M.3
-
72
-
-
46449131251
-
Xanthine oxidase interaction with vascular endothelial growth factor in human endothelial cell angiogenesis
-
B. Kou, J. Ni, M. Vatish, and D.R. Singer Xanthine oxidase interaction with vascular endothelial growth factor in human endothelial cell angiogenesis Microcirculation 15 2008 251 2567
-
(2008)
Microcirculation
, vol.15
, pp. 251-2567
-
-
Kou, B.1
Ni, J.2
Vatish, M.3
Singer, D.R.4
-
73
-
-
0025041309
-
Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation
-
A. Mora, M. Payá, J.L. Ríos, and M.J. Alcaraz Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation Biochem Pharmacol 40 1990 793 797
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 793-797
-
-
Mora, A.1
Payá, M.2
Ríos, J.L.3
Alcaraz, M.J.4
-
74
-
-
0029057329
-
Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin
-
C. Manach, C. Morand, O. Texier, M.L. Favier, G. Agullo, and C. Demigné Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin J Nutr 125 1995 1911 1922
-
(1995)
J Nutr
, vol.125
, pp. 1911-1922
-
-
Manach, C.1
Morand, C.2
Texier, O.3
Favier, M.L.4
Agullo, G.5
Demigné, C.6
|