Self double-stranded (ds)DNA induces IL-1β production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1407-1415

  Shin, Min Sun ^a   Kang, Youna ^a   Lee, Naeun ^a   Wahl, Elizabeth R ^a   Kim, Sang Hyun ^a,b   Kang, Ki Soo ^a,c   Lazova, Rossitza ^a   Kang, Insoo ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Kangwon National University   (South Korea)

^c Jeju National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CRYOPYRIN; DOUBLE STRANDED DNA; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INFLAMMASOME; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 9;

ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; CD4+ T LYMPHOCYTE; CRYOPYRIN GENE; CYTOKINE PRODUCTION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTERLEUKIN 1BETA GENE; MEMORY T LYMPHOCYTE; MONOCYTE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH17 CELL;

ADULT; AUTOANTIBODIES; CARRIER PROTEINS; CASPASE 1; CELL LINE, TUMOR; CELLS, CULTURED; DNA; HUMANS; INTERLEUKIN-1BETA; JURKAT CELLS; MONOCYTES; SERUM;

EID: 84873550853     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201195     Document Type: Article

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