U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes

Journal of Immunology

Volumn 188, Issue 10, 2012, Pages 4769-4775

  Shin, Min Sun ^a   Kang, Youna ^a   Lee, Naeun ^a   Kim, Sang Hyun ^a,b   Kang, Ki Soo ^a,c   Lazova, Rossitza ^a   Kang, Insoo ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Kangwon National University   (South Korea)

^c Jeju National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INFLAMMASOME; INTERLEUKIN 1BETA; POTASSIUM ION; REACTIVE OXYGEN METABOLITE; SMALL NUCLEAR RIBONUCLEOPROTEIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MONOCYTE; NLRP3 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; ANTIBODIES; ANTIGENS, CD14; CARRIER PROTEINS; HUMANS; INTERLEUKIN-1BETA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MONOCYTES; REACTIVE OXYGEN SPECIES; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR;

EID: 84861162164     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103355     Document Type: Article

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