High-dilution effects revisited. 2. Pharmacodynamic mechanisms

Homeopathy

Volumn 103, Issue 1, 2014, Pages 22-43

  Bellavite, Paolo ^a   Marzotto, Marta ^a   Olioso, Debora ^a   Moratti, Elisabetta ^a   Conforti, Anita ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Biophysics; High dilutions; Homeopathic potencies; Hormesis; Nanopharmacology; Similia rule; Systems biology; Water clusters; Water coherence domains

Indexed keywords

CELL PROTECTION; CELL STRUCTURE; CONCEPTUAL FRAMEWORK; DILUTION; DRUG RECEPTOR BINDING; GENE EXPRESSION; HOMEOPATHY; HORMESIS; IMMUNE RESPONSE; NANOMEDICINE; NONHUMAN; PHARMACODYNAMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION;

BIOPHYSICS; HIGH DILUTIONS; HOMEOPATHIC POTENCIES; HORMESIS; NANOPHARMACOLOGY; SIMILIA RULE; SYSTEMS BIOLOGY; WATER CLUSTERS; WATER COHERENCE DOMAINS;

ANIMALS; GENE EXPRESSION; HOMEOPATHY; HORMESIS; HUMANS; NANOPARTICLES; SYSTEMS BIOLOGY; WATER;

EID: 84892555013     PISSN: 14754916     EISSN: 14764245     Source Type: Journal    
DOI: 10.1016/j.homp.2013.08.002     Document Type: Review

References (248)

1. Bellavite P., Marzotto M., Olioso D., Moratti E., Conforti A. High-dilution effects revisited. 1. Physicochemical aspects. Homeopathy 2014, 103:4-21.
2. Witt C.M., Bluth M., Albrecht H., Weisshuhn T.E., Baumgartner S., Willich S.N. The invitro evidence for an effect of high homeopathic potencies - a systematic review of the literature. Complement Ther Med 2007, 15:128-138.
3. Bonamin L.V., Endler P.C. Animal models for studying homeopathy and high dilutions: conceptual critical review. Homeopathy 2010, 99:37-50.
4. Bellavite P., Magnani P., Marzotto M., Conforti A. Assays of homeopathic remedies in rodent behavioural and psychopathological models. Homeopathy 2009, 98:208-227.
5. Endler P., Thieves K., Reich C., et al. Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study. Homeopathy 2010, 99:25-36.
6. Poitevin B., Davenas E., Benveniste J. Invitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica. Br J Clin Pharmacol 1988, 25:439-444.
7. Cherruault Y., Guillez A., Sainte-Laudy J., Belon P. Étude mathematique et statistique des effets de dilutions successives de chlorhydrate d'histamine sur la réactivité des basophiles humains. Bio-Sciences 1989, 7:63-72.
8. Brown V., Ennis M. Flow-cytometric analysis of basophil activation: inhibition by histamine at conventional and homeopathic concentrations. Inflamm Res 2001, 50(2):S47-S48.
9. Lorenz I., Schneider E.M., Stolz P., Brack A., Strube J. Influence of the diluent on the effect of highly diluted histamine on basophil activation. Homeopathy 2003, 92:11-18.
10. Lorenz I., Schneider E.M., Stolz P., Brack A., Strube J. Sensitive flow cytometric method to test basophil activation influenced by homeopathic histamine dilutions. Forsch Komplementarmed Klass Naturheilkd 2003, 10:316-324.
11. Sainte-Laudy J., Boudjedaini N., Belon P. Differential effect of storage on molecular and ultra-molecular dilutions of histamine. Inflamm Res 2009, 58(Suppl. 1):30-31.
12. Sainte-Laudy J., Boujenaini N., Belon P. Confirmation of biological effects of high dilutions. Effects of submolecular concentrations of histamine and 1-, 3- and 4-methylhistamines on human basophil activation. Inflamm Res 2008, 57(Suppl. 1):S27-S28.
13. Chirumbolo S., Brizzi M., Ortolani R., Vella A., Bellavite P. Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study. Inflamm Res 2009, 58:755-764.
14. Sainte-Laudy J., Belon P. Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions. Homeopathy 2009, 98:186-197.
15. Guggisberg A.G., Baumgartner S.M., Tschopp C.M., Heusser P. Replication study concerning the effects of homeopathic dilutions of histamine on human basophil degranulation invitro. Complement Ther Med 2005, 13:91-100.
16. Walchli C., Baumgartner S. Flow cytometric analysis of the inhibition of human basophil activation by histamine high dilutions - a replication study. Int J High Dilution Res 2012, 11(40):172-173.
17. Sainte-Laudy J., Belon P. Application of flow cytometry to the analysis of the immunosuppressive effect of histamine dilutions on human basophil activation: effect of cimetidine. Inflamm Res 1997, 46:S27-S28.
18. Khuda-Bukhsh A.R., Bhattacharyya S.S., Paul S., Dutta S., Boujedaini N., Belon P. Modulation of signal proteins: a plausible mechanism to explain how a potentized drug Secale Cor 30C diluted beyond Avogadro's limit combats skin papilloma in mice. Evid Based Complement Alternat Med 2011, 2011. 286320.
19. Endler P.C., Pongratz W., Kastberger G., Wiegant F.A., Schulte J. The effect of highly diluted agitated thyroxine on the climbing activity of frogs. Vet Hum Toxicol 1994, 36:56-59.
20. -13) on lowland frogs. Forsch Komplementarmed Klass Naturheilkd 2003, 10:137-142.
21. Weber S., Endler P.C., Welles S.U., et al. The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic fields. Homeopathy 2008, 97:3-9.
22. Guedes J.R., Ferreira C.M., Guimaraes H.M., Saldiva P.H., Capelozzi V.L. Homeopathically prepared dilution of Rana catesbeiana thyroid glands modifies its rate of metamorphosis. Homeopathy 2004, 93:132-137.
23. Guedes J.R., Carrasco S., Ferreira C.M., et al. Ultra high dilution of triiodothyronine modifies cellular apoptosis in Rana catesbeiana tadpole tail invitro. Homeopathy 2011, 100:220-227.
24. Harrer B. Replication of an experiment on extremely diluted thyroxine and highland amphibians. Homeopathy 2013, 102:25-30.
25. Bellavite P., Conforti A., Pontarollo F., Ortolani R. Immunology and homeopathy. 2. Cells of the immune system and inflammation. Evid Based Complement Alternat Med 2006, 3:13-24.
26. Bellavite P., Conforti A., Ortolani R. Immunology and homeopathy. 3. Experimental studies on animal models. Evid Based Complement Alternat Med 2006, 3:171-186.
27. Bellavite P., Marzotto M., Chirumbolo S., Conforti A. Advances in homeopathy and immunology: a review of clinical research. Front Biosci (Schol Ed) 2011, 3:1363-1389.
28. Hostanska K., Rostock M., Melzer J., Baumgartner S., Saller R. A homeopathic remedy from arnica, marigold, St. John inverted question marks wort and comfrey accelerates invitro wound scratch closure of NIH 3T3 fibroblasts. BMC Complement Altern Med 2012, 12:100.
29. Lussignoli S., Bertani S., Metelmann H., Bellavite P., Conforti A. Effect of Traumeel S, a homeopathic formulation, on blood-induced inflammation in rats. Complement Ther Med 1999, 7:225-230.
30. Kawakami A.P., Sato C., Cardoso T.N., Bonamin L.V. Inflammatory process modulation by homeopathic Arnica montana 6CH: the role of individual variation. Evid Based Complement Alternat Med 2011, 2011. 917541.
31. de Oliveira S.M., de Oliveira C.C., Abud A.P., et al. Mercurius solubilis: actions on macrophages. Homeopathy 2011, 100:228-236.
32. de Araujo F.R., de Castro C.M., Severo M.S., Diniz M.F., Viana M.T., Evencio L.B. Effect of Mercurius solubilis on the bacteriological response in the alveolitis process in rats. Homeopathy 2009, 98:160-164.
33. Davenas E., Poitevin B., Benveniste J. Effect on mouse peritoneal macrophages of orally administered very high dilutions of silica. Eur J Pharmacol 1987, 135:313-319.
34. 2) as a homeopathic remedy. Pharmacological study of homeopathic high dilutions. Signals Images 1997, 191-199. Kluwer, Dordrecht. M. Bastide (Ed.).
35. Boericke W. Materia Medica with repertory 1927, Boericke & Tafel, Inc., Philadelphia.
36. Binsard A.M., Guillemain J., Platel A., Savini E.C., Tetau M. Étude psycho-pharmacologique de dilutions homéopathiques de Gelsemium et d'Ignatia. Ann Homeop Fr 1980, 22:35-50.
37. Guillemain J., Rousseau A., Dorfman P., Tetau M. Recherche en psychopharmacologie. Cah Biother 1989, 103:53-66.
38. Guermonprez M. Homéopathie, principles - clinique - techniques 2006, CEDH, Paris.
39. Schun Y., Cordell G.A. Cytotoxic steroids of Gelsemium sempervirens. J Nat Prod 1987, 50:195-198.
40. Dutt V., Thakur S., Dhar V.J., Sharma A. The genus Gelsemium: an update. Pharmacogn Rev 2010, 4:185-194.
41. Gahlot K., Abid M., Sharma A. Pharmacological evaluation of Gelsemium sempervirens roots for CNS depressant activity. Int J Pharm Tech Res 2012, 3:693-697.
42. Dutt V., Dhar V.J., Sharma A. Antianxiety activity of Gelsemium sempervirens. Pharm Biol 2010, 48:1091-1096.
43. Liu M., Shen J., Liu H., et al. Gelsenicine from Gelsemium elegans attenuates neuropathic and inflammatory pain in mice. Biol Pharm Bull 2011, 34:1877-1880.
44. Xu Y., Qiu H.Q., Liu H., et al. Effects of koumine, an alkaloid of Gelsemium elegans Benth., on inflammatory and neuropathic pain models and possible mechanism with allopregnanolone. Pharmacol Biochem Behav 2012, 101:504-514.
45. Venard C., Boujedaini N., Belon P., Mensah-Nyagan A.G., Patte-Mensah C. Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine. Neuroscience 2008, 153:154-161.
46. Venard C., Boujedaini N., Mensah-Nyagan A.G., Patte-Mensah C. Comparative analysis of gelsemine and Gelsemium sempervirens aftivity on neurosteroid allopregnanolone formation in the spinal cord and limbic system. Evid Based Complement Alternat Med 2011, 2011. 407617.
47. Bhattacharyya S.S., Mandal S.K., Biswas R., et al. Invitro studies demonstrate anticancer activity of an alkaloid of the plant Gelsemium sempervirens. Exp Biol Med (Maywood) 2008, 233:1591-1601.
48. Zhao Q.C., Hua W., Zhang L., et al. Antitumor activity of two gelsemine metabolites in rat liver microsomes. J Asian Nat Prod Res 2010, 12:731-739.
49. Rammal H., Soulimani R. Effects of high doses of Gelsemium sempervirens L. on GABA receptor and on the cellular and humoral immunity in mice. JMMS 2010, 1:40-44.
50. Das S., Das J., Samadder A., Bhattacharyya S.S., Das D., Khuda-Bukhsh A.R. Biosynthesized silver nanoparticles by ethanolic extracts of Phytolacca decandra, Gelsemium sempervirens, Hydrastis canadensis and Thuja occidentalis induce differential cytotoxicity through G2/M arrest in A375 cells. Colloids Surf B Biointerfaces 2013, 101:325-336.
51. Datta S., Mallick P., Bukhsh A.R. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing genotoxic effects produced by arsenic trioxide in mice: II. Comparative efficacy of an antibiotic, actinomycin D alone and in combination with either of two microdoses. Complement Ther Med 1999, 7:156-163.
52. Das S., Saha S.K., De A., Das D., Khuda-Bukhsh A.R. Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. Zhong Xi Yi Jie He Xue Bao 2012, 10:337-346.
53. Das D., De A., Dutta S., Biswas R., Boujedaini N., Khuda-Bukhsh A.R. Potentized homeopathic drug Arsenicum album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate. Zhong Xi Yi Jie He Xue Bao 2011, 9:752-760.
54. Paul A., Das S., Das J., Samadder A., Khuda-Bukhsh A.R. Cytotoxicity and apoptotic signalling cascade induced by chelidonine-loaded PLGA nanoparticles in HepG2 cells invitro and bioavailability of nano-chelidonine in mice invivo. Toxicol Lett 2013, 222:10-22.
55. Saha S.K., Khuda-Bukhsh A.R. Molecular approaches towards development of purified natural products and their structurally known derivatives as efficient anti-cancer drugs: current trends. Eur J Pharmacol 2013, 714:239-248.
56. de Oliveira C.C., de Oliveira S.M., Goes V.M., Probst C.M., Krieger M.A., Buchi D.F. Gene expression profiling of macrophages following mice treatment with an immunomodulator medication. J Cell Biochem 2008, 104:1364-1377.
57. Bigagli E., Luceri C., Bernardini S., Dei A., Dolara P. Extremely low copper concentrations affect gene expression profiles of human prostate epithelial cell lines. Chem Biol Interact 2010, 188:214-219.
58. Preethi K., Ellanghiyil S., Kuttan G., Kuttan R. Induction of apoptosis of tumor cells by some potentiated homeopathic drugs: implications on mechanism of action. Integr Cancer Ther 2012, 11:172-182.
59. Bellavite P., Marzotto M., Olioso D., et al. Cellular and transcriptional responses of SH-SY5Y human neurocytes following invitro exposure to Gelsemium sempervirens. Int J High Dilution Res 2012, 11:144-146.
60. Shepperd J. Chaos theory: implications for homeopathy. J Am Inst Homeopathy 1994, 87:22-29.
61. Bell F. The complex 'whole': exploring homoeopathic and spiritual considerations. Aust J Holist Nurs 2000, 7:31-35.
62. Milgrom L.R. Vitalism, complexity and the concept of spin. Homeopathy 2002, 91:26-31.
63. Bellavite P. Complexity science and homeopathy. A synthetic overview. Homeopathy 2003, 92:203-212.
64. Bell I.R., Lewis D.A., Lewis S.E., Brooks A.J., Schwartz G.E., Baldwin C.M. Strength of vital force in classical homeopathy: bio-psycho-social-spiritual correlates within a complex systems context. J Altern Complement Med 2004, 10:123-131.
65. Bell I.R., Howerter A., Jackson N., Aickin M., Bootzin R.R., Brooks A.J. Nonlinear dynamical systems effects of homeopathic remedies on multiscale entropy and correlation dimension of slow wave sleep EEG in young adults with histories of coffee-induced insomnia. Homeopathy 2012, 101:182-192.
66. Callard R., George A.J., Stark J. Cytokines, chaos, and complexity. Immunity 1999, 11:507-513.
67. Glattre E., Nygard J.F. Fractal meta-analysis and 'causality' embedded in complexity: advanced understanding of disease etiology. Nonlinear Dynamics Psychol Life Sci 2004, 8:315-344.
68. Martinez-Lavin M., Infante O., Lerma C. Hypothesis: the chaos and complexity theory may help our understanding of fibromyalgia and similar maladies. Semin Arthritis Rheum 2008, 37:260-264.
69. Higgins J.P. Nonlinear systems in medicine. Yale J Biol Med 2002, 75:247-260.
70. Del Prete G. The complexity of the CD4 T-cell responses: old and new T-cell subsets. Parassitologia 2008, 50:9-16.
71. Sukul N.C., Batuev A.S., Sabanov V., Kourzina N.P. Neuronal activity in the lateral hypothalamus of the cat the medial frontal cortex of the rat in response to homoeopathic drugs. Indian Biologist 1991, 23(2):17-21.
72. Sukul N.C., Sukul A. High dilution effects: physical and biochemical basis 2003, Kluwer, Dordrecht.
73. Levin M., Stevenson C.G. Regulation of cell behavior and tissue patterning by bioelectrical signals: challenges and opportunities for biomedical engineering. Annu Rev Biomed Eng 2012, 14:295-323.
74. Bell I.R., Baldwin C.M., Fernandez M., Schwartz G.E. Neural sensitization model for multiple chemical sensitivity: overview of theory and empirical evidence. Toxicol Ind Health 1999, 15:295-304.
75. Popp F.A. Principles of complementary medicine in terms of a suggested scientific basis. Indian J Exp Biol 2008, 46:378-383.
76. Ruiz G., Torres J.L., Michel O., Navarro R. Homeopathic effect on heart rate variability. Br Homeopath J 1999, 88:106-111.
77. Ruiz-Vega G., Perez-Ordaz L., Cortes-Galvan L., Juarez G. A kinetic approach to caffeine - Coffea cruda interaction. Homeopathy 2003, 92:19-29.
78. Ruiz-Vega G., Perez-Ordaz L., Leon-Hueramo O., Cruz-Vazquez E., Sanchez-Diaz N. Comparative effect of Coffea cruda potencies on rats. Homeopathy 2002, 91:80-84.
79. Ruiz-Vega G., Perez-Ordaz L., Proa-Flores P., Aguilar-Diaz Y. An evaluation of Coffea cruda effect on rats. Br Homeopath J 2000, 89:122-126.
80. Ruiz-Vega G., Poitevin B., Perez-Ordaz L. Histamine at high dilution reduces spectral density in delta band in sleeping rats. Homeopathy 2005, 94:86-91.
81. Ruiz-Vega G., Estevez-Delgado G. Non-linearity modeling of ultra-dilutions: the histamine disturbances case. Contributions and Contradictions About High Dilution Research 2008, 67-82. Springer Science. L.V. Bonamin (Ed.).
82. Bell I.R., Lewis D.A., Schwartz G.E., et al. Electroencephalographic cordance patterns distinguish exceptional clinical responders with fibromyalgia to individualized homeopathic medicines. J Altern Complement Med 2004, 10:285-299.
83. Bell I.R., Howerter A., Jackson N., Brooks A.J., Schwartz G.E. Multiweek resting EEG cordance change patterns from repeated olfactory activation with two constitutionally salient homeopathic remedies in healthy young adults. J Altern Complement Med 2012, 18:445-453.
84. Bellavite P., Conforti A., Marzotto M., et al. Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies. Evid Based Complement Alternat Med 2012, 2012. 954374.
85. Bellavite P., Signorini A. Pathology, complex systems and resonance. Fundamental Research in Ultra-high Dilution and Homoeopathy 1998, 105-116. Kluwer Acad. Publ., Dordrecht, The Netherlands. J. Schulte, P.C. Endler (Eds.).
86. Bellavite P., Signorini A. The emerging science of homeopathy: complexity, biodynamics, and nanopharmacology 2002, North Atlantic, Berkeley (CA).
87. Bellavite P. La complessità in medicina. Fondamenti di un approccio sistemico e dinamico alla salute, alla malattia e alle terapie integrate 2009, Tecniche Nuove, Milano.
88. Vandenberg L.N., Colborn T., Hayes T.B., et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 2012, 33:378-455.
89. Thangapazham R.L., Rajeshkumar N.V., Sharma A., et al. Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissues. Integr Cancer Ther 2006, 5:350-355.
90. Bellavite P., Chirumbolo S., Marzotto M. Hormesis and its relationship with homeopathy. Hum Exp Toxicol (BELLE Newsl) 2010, 16:11-18.
91. Bellavite P., Ortolani R., Pontarollo F., Pitari G., Conforti A. Immunology and homeopathy. 5. The rationale of the 'Simile'. Evid Based Complement Alternat Med 2007, 4:149-163.
92. Torres J.L. Enhanced susceptibility in homeopathic experiments 2003, Royal London Homeopathic Hospital Ed., London.
93. Van Wijk R., Wiegant F.A. Postconditioning hormesis and the homeopathic similia principle: molecular aspects. Hum Exp Toxicol 2010, 29:561-565.
94. Wiegant F., Van W.R. The similia principle: results obtained in a cellular model system. Homeopathy 2010, 99:3-14.
95. Anick D.J., Ives J.A. The silica hypothesis for homeopathy: physical chemistry. Homeopathy 2007, 96:189-195.
96. Ives J.A., Moffett J.R., Arun P., et al. Enzyme stabilization by glass-derived silicates in glass-exposed aqueous solutions. Homeopathy 2010, 99:15-24.
97. Torres J.L., Ruiz G. Stochastic resonance and the homoeopathic effect. Br Homeopath J 1996, 85:134-140.
98. Schwartz G.E., Russek L.G., Bell I.R., Riley D. Plausibility of homeopathy and conventional chemical therapy: the systemic memory resonance hypothesis. Med Hypotheses 2000, 54:634-637.
99. Wiesenfeld K., Moss F. Stochastic resonance and the benefits of noise: from ice ages to crayfish and SQUIDs. Nature 1995, 373:33-36.
100. Yu H., Wang J., Liu C., Deng B., Wei X. Stochastic resonance on a modular neuronal network of small-world subnetworks with a subthreshold pacemaker. Chaos 2011, 21. 047502.
101. Teissie J. Biophysical effects of electric fields on membrane water interfaces: a mini review. Eur Biophys J 2007, 36:967-972.
102. 2+ oscillations. Phys Lett A 2003, 316:304-310.
103. Freier E., Wolf S., Gerwert K. Proton transfer via a transient linear water-molecule chain in a membrane protein. Proc Natl Acad Sci U S A 2011, 108:11435-11439.
104. Nitzan A. Ultrafast relaxation in water 1999, 472-475.
105. Woutersen S., Bakker H.J. Resonant intermolecular transfer of vibrational energy in liquid water 1999, 507-509.
106. Grotthus C.J.T. Sur la decomposition de l'eau et des corps qu'elle tient en dissolution à l'aide de l'electricitè galvanique. Ann Chim 1806, 58:54-73.
107. Elia V., Napoli E., Niccoli M., Nonatelli L., Ramaglia A., Ventimiglia E. New physico-chemical properties of extremely diluted aqueous solutions. A calorimetric and conductivity study at 25°C. J Thermal Anal Calorim 2004, 331-342.
108. Holt J.K. Methods for probing water at the nanoscale. Microfluid Nanofluid 2008, 5:425-442.
109. Witt C., Ludtke R., Weisshuhn T.E., Willich S.N. High homeopathic potencies are different from potentized solvent when investigated with the REDEM technology. Forsch Komplementarmed Klass Naturheilkd 2005, 12:6-13.
110. Cifra M., Fields J.Z., Farhadi A. Electromagnetic cellular interactions. Prog Biophys Mol Biol 2011, 105:223-246.
111. Kolomytkin O.V., Dunn S., Hart F.X., Frilot C., Kolomytkin D., Marino A.A. Glycoproteins bound to ion channels mediate detection of electric fields: a proposed mechanism and supporting evidence. Bioelectromagnetics 2007, 28:379-385.
112. Weaver J.C., Astumian R.D. The response of living cells to very weak electric fields: the thermal noise limit. Science 1990, 247:459-462.
113. Ho M.W., Popp F.A., Warnke U. Bioelectrodynamics and biocommunication 1994, World Scientific, Singapore.
114. Popp F.A. Properties of biophotons and their theoretical implications. Indian J Exp Biol 2003, 41:391-402.
115. Schutgens F.W., Neogi P., van Wijk E.P., Van W.R., Wikman G., Wiegant F.A. The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment. Phytother Res 2009, 23:1103-1108.
116. Meyl K. DNA and cell resonance: magnetic waves enable cell communication. DNA Cell Biol 2012, 31:422-426.
117. Shang C. Emerging paradigms in mind-body medicine. J Altern Complement Med 2001, 7:83-91.
118. Bajpai R., Brizhik L., Del Giudice E., Finelli F., Popp F.A., Schlebusch K.P. Light as a trigger and a probe of the internal dynamics of living organisms. J Acupunct Meridian Stud 2010, 3:291-297.
119. Vickland V., Rogers C., Craig A., Tran Y. Electrodermal activity as a possible physiological marker for acupuncture. Complement Ther Clin Pract 2008, 14:83-89.
120. Pontarollo F., Rapacioli G., Bellavite P. Increase of electrodermal activity of heart meridian during physical exercise: the significance of electrical values in acupuncture and diagnostic importance. Complement Ther Clin Pract 2010, 16:149-153.
121. Smith C.W. Quanta and coherence effects in water and living systems. J Altern Complement Med 2004, 10:69-78.
122. Benveniste J., Guillonnet D. QED and digital biology. Riv Biol 2004, 97:169-172.
123. Thomas Y., Schiff M., Belkadi L., Jurgens P., Kahhak L., Benveniste J. Activation of human neutrophils by electronically transmitted phorbol-myristate acetate. Med Hypotheses 2000, 54:33-39.
124. Rossi C., Foletti A., Magnani A., Lamponi S. New perspectives in cell communication: bioelectromagnetic interactions. Semin Cancer Biol 2011, 21:207-214.
125. Jerman I., Ruziè R., Krasovec R., Mogilnicki L. Electrical transfer of molecule information into water, its storage, and bioeffects on plants and bacteria. Electromagn Biol Med 2005, 24:341-353.
126. Liboff A.R. Electric-field ion cyclotron resonance. Bioelectromagnetics 1997, 18:85-87.
127. Pazur A. Characterisation of weak magnetic field effects in an aqueous glutamic acid solution by nonlinear dielectric spectroscopy and voltammetry. Biomagn Res Technol 2004, 2:8.
128. Liboff A.R. Electric polarization and the viability of living systems: ion cyclotron resonance-like interactions. Electromagn Biol Med 2009, 28:124-134.
129. Foletti A., Lisi A., Ledda M., de Carlo F., Grimaldi S. Cellular ELF signals as a possible tool in informative medicine. Electromagn Biol Med 2009, 28:71-79.
130. Foletti A., Grimaldi S., Lisi A., Ledda M., Liboff A.R. Bioelectromagnetic medicine: the role of resonance signaling. Electromagn Biol Med 2013 Jan 16, [Epub ahead of print]. http://dx.doi.org/10.3109/15368378.2012.743908.
131. Montagnier L., Aissa J., Del Giudice E., Lavallee C., Tedeschi A. DNA waves and water. J Phys Conf Ser 2011, 306. 012007.
132. Montagnier L., Aissa J., Ferris S., Montagnier J.L., Lavallee C. Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences. Interdiscip Sci: Comput Life Sci 2009, 1:81-90.
133. Montagnier L., Aissa J., Lavallee C., Mbamy M., Varon J., Chenal H. Electromagnetic detection of HIV DNA in the blood of AIDS patients treated by antiretroviral therapy. Interdiscip Sci: Comput Life Sci 2009, 1:245-253.
134. Foletti A., Ledda M., D'Emilia E., Grimaldi S., Lisi A. Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. J Altern Complement Med 2011, 17:701-704.
135. Foletti A., Ledda M., D'Emilia E., Grimaldi S., Lisi A. Experimental finding on the electromagnetic information transfer of specific molecular signals mediated through the aqueous system on two human cellular models. J Altern Complement Med 2012, 18:258-261.
136. Jonas W.B., Ives J.A., Rollwagen F., et al. Can specific biological signals be digitized?. FASEB J 2006, 20:23-28.
137. Fuxreiter M., Mezei M., Simon I., Osmany R. Interfacial water as a 'hydration fingerprint' in the noncognate complex of BamHI. Biophys J 2005, 89:903-911.
138. Moukhametzianov R., Klare J.P., Efremov R., et al. Development of the signal in sensory rhodopsin and its transfer to the cognate transducer. Nature 2006, 440:115-119.
139. Czerlinski G., Ypma T. The targets of information-carrying nanodomains. J Nanosci Nanotechnol 2012, 12:2239-2247.
140. Bell I.R., Koithan M. A model for homeopathic remedy effects: low dose nanoparticles, allostatic cross-adaptation, and time-dependent sensitization in a complex adaptive system. BMC Complement Altern Med 2012, 12:191.
141. Szolnoki Z. A dynamically changing intracellular water network serves as a universal regulator of the cell: the water-governed cycle. Biochem Biophys Res Commun 2007, 357:331-334.
142. Khesbak H., Savchuk O., Tsushima S., Fahmy K. The role of water H-bond imbalances in B-DNA substate transitions and peptide recognition revealed by time-resolved FTIR spectroscopy. J Am Chem Soc 2011, 133:5834-5842.
143. Wei D., Wilson W.D., Neidle S. Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster. J Am Chem Soc 2013, 135:1369-1377.
144. Marchettini N., Del G.E., Voeikov V., Tiezzi E. Water: a medium where dissipative structures are produced by a coherent dynamics. J Theor Biol 2010, 265:511-516.
145. Shahabi S., Kasariyans A., Noorbakhsh F. Like cures like: a neuroimmunological model based on electromagnetic resonance. Electromagn Biol Med 2013 Jan 23, http//dx.doi.org/10.3109/15368378.2012.743911. [Epub ahead of print].
146. Bellavite P., Lussignoli S., Semizzi M., Ortolani R., Signorini A. The similia principle. From cellular models to regulation of homeostasis. Br Homeopath J 1997, 86:73-85.
147. Bellavite P., Andrioli G., Lussignoli S., Signorini A., Ortolani R., Conforti A. Scientific reappraisal of the "Principle of Similarity". Med Hypotheses 1997, 49:203-212.
148. Andrioli G., Lussignoli S., Gaino S., Benoni G., Bellavite P. Study on paradoxical effects of NSAIDs on platelet activation. Inflammation 1997, 21:519-530.
149. Bond R.A. Is paradoxical pharmacology a strategy worth pursuing?. Trends Pharmacol Sci 2001, 22:273-276.
150. Yun A.J. The intellectual lineage of paradoxical pharmacology strategy. Med Hypotheses 2005, 65:815.
151. Teixeira M.Z. 'Paradoxical strategy for treating chronic diseases': a therapeutic model used in homeopathy for more than two centuries. Homeopathy 2005, 94:265-266.
152. Wiegant F.A., Souren J.E.M., Van Wijk R. Stimulation of survival capacity in heat shocked cells by subsequent exposure to minute amounts of chemical stressors; role of similarity in hsp-inducing effects. Hum Exp Toxicol 1999, 18:460-470.
153. Bernardini S., Dei A. Hormesis may provide a central concept for homeopathy development. Toxicol Appl Pharmacol 2006, 211:84.
154. Calabrese E.J. Hormesis: why it is important to toxicology and toxicologists. Environ Toxicol Chem 2008, 27:1451-1474.
155. Jonas W.B., Ives J.A. Should we explore the clinical utility of hormesis?. Hum Exp Toxicol 2008, 27:123-127.
156. Calabrese E.J., Jonas W.B. Homeopathy: clarifying its relationship to hormesis. Hum Exp Toxicol 2010, 29:531-536.
157. Van Wijk R., Wiegant F.A. Postconditioning hormesis and the similia principle. Front Biosci (Elite Ed) 2011, 3:1128-1138.
158. Schulz H. Uber die Theorie der Arzneimittelwirkung. Virchow's Archiv 1877, 108:423-434.
159. Martius F. Das Arndt-Schulz Grundgesetz. Muench Med Wochenschr 1923, 70:1005-1006.
160. Boyd L.J. A study of the simile in medicine 1936, Boericke and Tafel, Philadelphia.
161. Calabrese E.J., Baldwin L.A. The marginalization of hormesis. Hum Exp Toxicol 2000, 19:32-40.
162. Calabrese E.J., Bachmann K.A., Bailer A.J., et al. Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol 2007, 222:122-128.
163. Stebbing A.R.D. Hormesis: the stimulation of growth by low levels of inhibitors. Sci Total Environ 1982, 22:213-234.
164. Wagner H., Kreher B., Jurcic K. Invitro stimulation of human granulocytes and lymphocytes by pico-and femtogram quantities of cytostatic agents. Arzneimittelforschung 1988, 38:273-275.
165. Von Zglinicki T., Edwall C., Ostlund E., et al. Very low cadmium concentrations stimulate DNA synthesis cell growth. J Cell Sci 1992, 103:1073-1081.
166. Van Wijk R., Wiegant F.A.C., Souren J.E.M., Ovelgonne J.H., van Aken J.M., Bol A.W.J.M. A molecular basis for understanding the benefits from subharmful doses of toxicants. Biomed Ther 1997, 15:4-13.
167. Wiegant F.A., Prins H.A., Van W.R. Postconditioning hormesis put in perspective: an overview of experimental and clinical studies. Dose Response 2011, 9:209-224.
168. Crain S.M., Shen K.F. Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment. Proc Natl Acad Sci U S A 1995, 92:10540-10544.
169. Shen K.F., Crain S.M. Ultra-low doses of naltrexone or etorphine increase morphine's antinociceptive potency and attenuate tolerance/dependence in mice. Brain Res 1997, 757:176-190.
170. da Silva J.L., Morishita T., Escalante B., et al. Dual role of heme oxygenase in epithelial cell injury: contrasting effects of short-term and long-term exposure to oxidant stress. J Lab Clin Med 1996, 128:290-296.
171. Andrioli G., Lussignoli S., Ortolani R., Minuz P., Vella F., Bellavite P. Dual effects of diclofenac on human platelet adhesion invitro. Blood Coagul Fibrinolysis 1996, 7:153-156.
172. Bellavite P., Carletto A., Biasi D., et al. Studies of skin-window exudate human neutrophils: complex patterns of adherence to serum-coated surfaces in dependence on FMLP doses. Inflammation 1994, 18:575-587.
173. Chirumbolo S., Conforti A., Lussignoli S., Metelmann H., Bellavite P. Effects of Podophyllum peltatum compounds in various preparations dilutions on human neutrophil functions invitro. Br Homeopath J 1997, 86:16-26.
174. Betti L., Brizzi M., Nani D., Peruzzi M. Effect of high dilutions of Arsenicum album on wheat seedlings from seed poisoned with the same substance. Br Homeopath J 1997, 86:86-89.
175. Betti L., Borghini F., Nani D. Plant models for fundamental research in homeopathy. Homeopathy 2003, 92:129-130.
176. Pongratz W., Nograsek A., Endler P.C. Highly diluted agitated silver nitrate and wheat seedling development. Effect kinetics of a process of successive agitation phases. Fundamental Research in Ultra High Dilution and Homeopathy 2000, 143-154. Kluwer, Dordrecht. J. Schulte, P.C. Endler (Eds.).
177. Delbancut A., Dorfman P., Cambar J. Protective effect of very low concentrations of heavy metals cadmium and cisplatin against cytotoxic doses of these metals on renal tubular cell cultures. Br Homeopath J 1993, 82:123-124.
178. Walchli C., Baumgartner S., Bastide M. Effect of low doses and high homeopathic potencies in normal and cancerous human lymphocytes: an invitro isopathic study. J Altern Complement Med 2006, 12:421-427.
179. Jonas W., Lin Y., Tortella F. Neuroprotection from glutamate toxicity with ultra-low dose glutamate. Neuroreport 2001, 12:335-339.
180. Marotta D., Marini A., Banaudha K., et al. Non-linear effects of cycloheximide in glutamate-treated cultured rat cerebellar neurons. Neurotoxicology 2002, 23:307-312.
181. Chirumbolo S., Marzotto M., Conforti A., Vella A., Ortolani R., Bellavite P. Bimodal action of the flavonoid quercetin on basophil function: an investigation of the putative biochemical targets. Clin Mol Allergy 2010, 8:13.
182. Endler P.C., Pongratz W., Kastberger G., Wiegant F.A.C., Haidvogl M. Climbing activity in frogs the effect of highly diluted succussed thyroxine. Br Homeopath J 1991, 80:194-200.
183. Endler P.C., Pongratz W., Van Wijk R., et al. A zoological example on ultra high dilution research. Energetic coupling between the dilution the organism in a model of amphibia. Ultra High Dilution 1994, 39-68. Kluwer Acad. Publ., Dordrecht. P.C. Endler, J. Schulte (Eds.).
184. Doutremepuich C., Aguejouf O., Belon P. Effects of ultra-low-dose aspirin on embolization in a model of laser-induced thrombus formation. Semin Thromb Hemost 1996, 22(Suppl. 1):67-70.
185. Eizayaga F.X., Aguejouf O., Desplat V., Doutremepuich C. Beneficial effect of ultra-low-dose aspirin in platelet activity alterations and haemorrhage observed in experimental portal hypertension. Thrombosis 2012, 2012. 430460.
186. Aguejouf O., Eizayaga F., Desplat V., Belon P., Doutremepuich C. Prothrombotic and hemorrhagic effects of aspirin. Clin Appl Thromb Hemost 2009, 15:523-528.
187. Cohen M.V., Downey J.M. Myocardial preconditioning promises to be a novel approach to the treatment of ischemic heart disease. Annu Rev Med 1996, 47:21-29.
188. Kim S.H., Naveen K.C., Kim H.J., et al. Glucose-containing flavones - their synthesis and antioxidant and neuroprotective activities. Bioorg Med Chem Lett 2009, 19:6009-6013.
189. Gupta C. The role of estrogen receptor, androgen receptor and growth factors in diethylstilbestrol-induced programming of prostate differentiation. Urol Res 2000, 28:223-229.
190. Weiner H.L., Friedman H., Miller A., et al. Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Annu Rev Immunol 1994, 12:809-837.
191. Faria A.M., Weiner H.L. Oral tolerance. Immunol Rev 2005, 206:232-259.
192. Ono T., Inoue M., Rashid M.H., Sumikawa K., Ueda H. Stimulation of peripheral nociceptor endings by low dose morphine and its signaling mechanism. Neurochem Int 2002, 41:399-407.
193. Kayser V., Benoist J.M., Neil A., Gautron M., Guilbaud G. Behavioural and electrophysiological studies on the paradoxical antinociceptive effects of an extremely low dose of naloxone in an animal model of acute and localized inflammation. Exp Brain Res 1988, 73:402-410.
194. Powell K.J., Abul-Husn N.S., Jhamandas A., Olmstead M.C., Beninger R.J., Jhamandas K. Paradoxical effects of the opioid antagonist naltrexone on morphine analgesia, tolerance, and reward in rats. J Pharmacol Exp Ther 2002, 300:588-596.
195. Singh V.P., Patil C.S., Jain N.K., Singh A., Kulkarni S.K. Paradoxical effects of opioid antagonist naloxone on SSRI-induced analgesia and tolerance in mice. Pharmacology 2003, 69:115-122.
196. Bastide P., Aubin B., Baronnet S. E'tude pharmacologique d'une preparation d'Apis mel. (7CH) vis-à-vis de l'erythème aux rayons U.V. chez le cobayes albinos. Ann Homeop Fr 1975, 3:289-294.
197. Bildet J., Guyot M., Bonini F., Grignon M.C., Poitevin B., Quilichini R. Mise en évidence des effets de dilutions d'Apis mellifica et d'Apium virus vis-à-vis de l'erythème provoqué par un rayonnement U.V. chez le cobaye. Ann Pharm Fr 1989, 47:24-32.
198. Conforti A., Signorini A., Bellavite P. Effects of high dilutions of histamin and other natural compounds on acute inflammation in rats. Omeomed 1993, Vol 92:163-169. Editrice Compositori, Bologna. C. Bornoroni (Ed.).
199. Park H.J., Lee S.H., Son D.J., et al. Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit. Arthritis Rheum 2004, 50:3504-3515.
200. Lee J.Y., Kang S.S., Kim J.H., Bae C.S., Choi S.H. Inhibitory effect of whole bee venom in adjuvant-induced arthritis. InVivo 2005, 19:801-805.
201. Naidoo P., Pellow J. A randomized placebo-controlled pilot study of Cat saliva 9cH and Histaminum 9cH in cat allergic adults. Homeopathy 2013, 102:123-129.
202. Ugazio G., Koch R.R., Rechnagel R.O. Mechanism of protection against carbon tetrachloride by prior carbon tetrachloride administration. Exp Mol Path 1972, 16:281-285.
203. Pound A.W., Lawson T.A. Reduction of carbon tetrachloride toxicity by prior administration of a single small dose in mice and rats. Br J Exp Pathol 1975, 56:172-179.
204. Conforti A., Lussignoli S., Bertani S., Ortolani R., Verlato G., Bellavite P. Intraperitoneal administration of adjuvant inhibits the development of adjuvant arthritis in rats. Int J Immunopathol Pharmacol 1995, 8:113-121.
205. Conforti A., Lussignoli S., Bertani S., et al. Specific and long-lasting suppression of rat adjuvant arthritis by low-dose Mycobacterium butyricum. Eur J Pharmacol 1997, 324:241-247.
206. Conforti A., Lussignoli S., Bertani S., et al. Cytokine and nitric oxide levels in a rat model of immunologic protection from adjuvant-induced arthritis. Int J Immunopathol Pharmacol 2001, 14:153-160.
207. Lapp C., Wurmser L., Ney J. Mobilization de l'arsenic fixéchez le cobaye sous l'influence des doses infinitesimales d'arseniate. Thérapie 1955, 10:625-638.
208. Cazin J.C., Cazin M., Gaborit J.L., et al. A study of the effect of decimal and centesimal dilutions of arsenic on the retention and mobilisation of arsenic in the rat. Hum Toxicol 1987, 6:315-320.
209. Kundu S.N., Mitra K., Bukhsh A.R. Efficacy of a potentized homoeopathic drug (Arsenicum-album-30) in reducing cytotoxic effects produced by arsenic trioxide in mice: III. Enzymatic changes and recovery of tissue damage in liver. Complement Ther Med 2000, 8:76-81.
210. Banerjee P., Biswas S.J., Belon P., Khuda-Bukhsh A.R. A potentized homeopathic drug, arsenicum album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice. J Vet Med A Physiol Pathol Clin Med 2007, 54:370-376.
211. Banerjee P., Bhattacharyya S.S., Pathak S., Naoual B., Belon P., Khuda-Bukhsh A.R. Comparative efficacy of two microdoses of a potentized homeopathic drug, arsenicum album, to ameliorate toxicity induced by repeated sublethal injections of arsenic trioxide in mice. Pathobiology 2008, 75:156-170.
212. De Gerlache J., Lans M. Modulation of experimental rat liver carcinogenesis by ultra low doses of the carcinogens. Ultra Low Doses 1991, 17-26. Taylor Francis, London. C. Doutremepuich (Ed.).
213. Waddell W.J. Critique of dose response in carcinogenesis. Hum Exp Toxicol 2006, 25:413-436.
214. Cui X., Su J., Li Y., et al. Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model. Intensive Care Med 2010, 36:148-156.
215. Magnani P., Conforti A., Zanolin E., Marzotto M., Bellavite P. Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice. Psychopharmacology (Berl) 2010, 210:533-545.
216. Bode A.M., Dong Z. The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects. Crit Rev Oncol Hematol 2002, 42:5-24.
217. Van Wijk R., Wiegant F.A.C. Stimulation of self-recovery by similia principle. Mode of testing in fundamental research. Br Homeopath J 1995, 84:131-139.
218. Bellavite P., Chirumbolo S., Lippi G., Andrioli G., Bonazzi L., Ferro I. Dual effects of formylpeptides on the adhesion of endotoxin-primed human neutrophils. Cell Biochem Funct 1993, 11:231-239.
219. Bellavite P., Chirumbolo S., Santonastaso C., Biasi D., Lussignoli S., Andrioli G. Dose-dependence of the various functional responses of neutrophils to formylpeptides. Activation, regulation, and inverse effects according to the agonist dose and cell condition. Signals and Images 1997, 111-119. Kluwer Acad. Publ., Dordrecht. M. Bastide (Ed.).
220. Preethi K.C., Kuttan G., Kuttan R. Anti-tumour activity of Ruta graveolens extract. Asian Pac J Cancer Prev 2006, 7:439-443.
221. Sunila E.S., Kuttan R., Preethi K.C., Kuttan G. Dynamized preparations in cell culture. Evid Based Complement Alternat Med 2009, 6:257-263.
222. Doutremepuich C., De Seze O., Anne M.C., Hariveau E., Quilichini R. Platelet aggregation on whole blood after administration of ultra low dosage acetylsalicylic acid in healthy volunteers. Thromb Res 1987, 47:373-377.
223. Doux J.D., Bazar K.A., Lee P.Y., Yun A.J. Can chronic use of anti-inflammatory agents paradoxically promote chronic inflammation through compensatory host response?. Med Hypotheses 2005, 65:389-391.
224. Oberbaum M., Samuels N., Singer S.R. Hormesis is not homeopathy. Toxicol Appl Pharmacol 2005, 206:365.
225. Teixeira M.Z. Homeopathic use of modern medicines: utilisation of the curative rebound effect. Med Hypotheses 2003, 60:276-283.
226. Teixeira M.Z. Antidepressants, suicidality and rebound effect: evidence of similitude?. Homeopathy 2009, 98:114-121.
227. Wilder J. Das "Ausgangswert-Gesetz", ein unbeachtes biologisches Gesetz und seine Bedeutung fur Forschung und Praxis. Zeit d Gesamte Neur u Psych 1931, 137:317.
228. Wilder J. Stimulus and response: the law of initial value 1967, Wright, Bristol.
229. Lorenz E.N. Predictability does the flap of a butterfly's wings in Brazil set off a tornado in Texas?. Address at the Annual Meeting of the American Association for the Advancement of Science. Washington, DC 1979, Cited in: The Essence of Chaos by Edward N. Lorenz, Seattle, WA: University of Washington Press 1993.
230. Firth W.J. Chaos-predicting the unpredictable. Br Med J 1991, 303:1565-1568.
231. Shinbrot T., Grebogi C., Ott E., Yorke J.A. Using small perturbations to control chaos. Nature 1993, 363:411-417.
232. Moss F. Chaos under control. Nature 1994, 370:596-597.
233. Ramo P., Kesseli J., Yli-Harja O. Perturbation avalanches and criticality in gene regulatory networks. J Theor Biol 2006, 242:164-170.
234. Schwartz G.E., Russek L.G. Dynamical energy systems and modern physics: fostering the science and spirit of complementary and alternative medicine. Altern Ther Health Med 1997, 3:46-56. [see comments].
235. Song L.Z., Schwartz G.E., Russek L.G. Heart-focused attention and heart-brain synchronization: energetic and physiological mechanisms. Altern Ther Health Med 1998, 4:44-52.
236. Balleza E., varez-Buylla E.R., Chaos A., Kauffman S., Shmulevich I., Aldana M. Critical dynamics in genetic regulatory networks: examples from four kingdoms. PLoS ONE 2008, 3:e2456.
237. Schubert C., Lambertz M., Nelesen R.A., Bardwell W., Choi J.B., Dimsdale J.E. Effects of stress on heart rate complexity - a comparison between short-term and chronic stress. Biol Psychol 2009, 80:325-332.
238. Morita K., Tsumoto K., Aihara K. Possible effects of depolarizing GABAA conductance on the neuronal input-output relationship: a modeling study. J Neurophysiol 2005, 93:3504-3523.
239. Gupta K., Singh H.P., Biswal B., Ramaswamy R. Adaptive targeting of chaotic response in periodically stimulated neural systems. Chaos 2006, 16. 023116.
240. Qi Y., Watts A.L., Kim J.W., Robinson P.A. Firing patterns in a conductance-based neuron model: bifurcation, phase diagram, and chaos. Biol Cybern 2013, 107:15-24.
241. Mishra N., Muraleedharan K.C., Paranjpe A.S., Munta D.K., Singh H., Nayak C. An exploratory study on scientific investigations in homeopathy using medical analyzer. J Altern Complement Med 2011, 17:705-710.
242. Mathur M. The concept of miasm - evolution and present day perspective. Homeopathy 2009, 98:177-180.
243. Milgrom L.R. Patient-practitioner-remedy (PPR) entanglement. Part 6. Miasms revisited: non-linear quantum theory as a model for the homeopathic process. Homeopathy 2004, 93:154-158.
244. Bellavite P., Pettigrew A. Miasms and modern pathology. Homeopathy 2004, 93:65-66.
245. Bell I.R., Baldwin C.M., Schwartz G.E. Translating a nonlinear systems theory model for homeopathy into empirical tests. Altern Ther Health Med 2002, 8:58-66.
246. Gulmen F.M. Energy medicine. Am J Chin Med 2004, 32:651-658.
247. Schmidt J.M. Is homeopathy a science? - continuity and clash of concepts of science within holistic medicine. J Med Humanit 2009, 30:83-97.
248. Bell I.R., Koithan M., Pincus D. Methodological implications of nonlinear dynamical systems models for whole systems of complementary and alternative medicine. Forsch Komplementmed 2012, 19(Suppl. 1):15-21.