-
1
-
-
26644464600
-
Identification of MMP-15 as an anti-apoptotic factor in cancer cells
-
DOI 10.1074/jbc.M508155200
-
Abraham, R., Schafer, J., Rothe, M., Bange, J., Knyazev, P., Ullrich, A., 2005. Identification of MMP-15 as an anti-apoptotic factor in cancer cells. J. Biol. Chem. 280, 34123-34132. (Pubitemid 41443136)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.40
, pp. 34123-34132
-
-
Abraham, R.1
Schafer, J.2
Rothe, M.3
Bange, J.4
Knyazev, P.5
Ullrich, A.6
-
2
-
-
0035215395
-
Proteasome inhibition in cancer: Development of PS-341
-
Adams, J., 2001. Proteasome inhibition in cancer: development of PS-341. Semin. Oncol. 28, 613-619. (Pubitemid 33134421)
-
(2001)
Seminars in Oncology
, vol.28
, Issue.6
, pp. 613-619
-
-
Adams, J.1
-
3
-
-
2342613652
-
The proteasome: A suitable anti-neoplastic target
-
Adams, J., 2004. The proteasome: a suitable anti-neoplastic target. Nat. Rev. Cancer 4, 349-360.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
4
-
-
0043026772
-
Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes
-
Adhami, V.M., Aziz, M.H., Mukhtar, H., Ahmad, N., 2003. Activation of pro death Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes. Clin. Cancer Res. 9, 3176-3182. (Pubitemid 36993280)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.8
, pp. 3176-3182
-
-
Adhami, V.M.1
Aziz, M.H.2
Mukhtar, H.3
Ahmad, N.4
-
5
-
-
0034005776
-
Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells
-
Ahmad, N., Gupta, S., Husain, M.M., Heiskanen, K.M., Mukhtar, H., 2000. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells. Clin. Cancer Res. 6, 1524-1528. (Pubitemid 30226242)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.4
, pp. 1524-1528
-
-
Ahmad, N.1
Gupta, S.2
Husain, M.M.3
Heiskanen, K.M.4
Mukhtar, H.5
-
6
-
-
0031745571
-
Signal transduction and signal modulation by cell adhesion receptors: The role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins
-
Aplin, A.E., Howe, A., Alahari, S.K., Juliano, R.L., 1998. Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol. Rev. 50, 197-263. (Pubitemid 28304026)
-
(1998)
Pharmacological Reviews
, vol.50
, Issue.2
, pp. 197-263
-
-
Aplin, A.E.1
Howe, A.2
Alahari, S.K.3
Juliano, R.L.4
-
7
-
-
36348987143
-
The value of natural products to future pharmaceutical discovery
-
DOI 10.1039/b602241n
-
Baker, D.D., Chu, M., Oza, U, Rajgarhia, V., 2007. The value of natural products to future pharmaceutical discovery. Nat. Prod. Rep. 24, 1225-1244. (Pubitemid 350151353)
-
(2007)
Natural Product Reports
, vol.24
, Issue.6
, pp. 1225-1244
-
-
Baker, D.D.1
Chu, M.2
Oza, U.3
Rajgarhia, V.4
-
8
-
-
33745323666
-
Validating cancer drug targets
-
DOI 10.1038/nature04873, PII NATURE04873
-
Benson, J.D., Chen, Y.N., Cornell-Kennon, S.A., Dorsch, M., Kim, S., Leszczyniecka, M., Sellers, W.R., Lengauer, C, 2006. Validating cancer drug targets. Nature 441, 451-456. (Pubitemid 44050140)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 451-456
-
-
Benson, J.D.1
Chen, Y.-N.P.2
Cornell-Kennon, S.A.3
Dorsch, M.4
Kim, S.5
Leszczyniecka, M.6
Sellers, W.R.7
Lengauer, C.8
-
9
-
-
0033152429
-
Telomerase and the maintenance of chromosome ends
-
DOI 10.1016/S0955-0674(99)80043-X
-
Bryan, T.M., Cech, T.R., 1999. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11, 318-324. (Pubitemid 29273801)
-
(1999)
Current Opinion in Cell Biology
, vol.11
, Issue.3
, pp. 318-324
-
-
Bryan, T.M.1
Cech, T.R.2
-
10
-
-
79956315031
-
Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: Cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target
-
Bhattacharyya, S.S., Paul, S., De, A., Das, D., Samadder, A., Boujedaini, N., Khuda-Bukhsh, A.R., 2011. Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target. Toxicol. Appl. Pharmacol. 253, 270-281.
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.253
, pp. 270-281
-
-
Bhattacharyya, S.S.1
Paul, S.2
De, A.3
Das, D.4
Samadder, A.5
Boujedaini, N.6
Khuda-Bukhsh, A.R.7
-
11
-
-
0029162563
-
Telomere elongation in immortal human cells without detectable telomerase activity
-
Bryan, T.M., Englezou, A., Gupta, J., Bacchetti, S., Reddel, R.R., 1995. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO. J. 14, 4240-4248.
-
(1995)
EMBO. J.
, vol.14
, pp. 4240-4248
-
-
Bryan, T.M.1
Englezou, A.2
Gupta, J.3
Bacchetti, S.4
Reddel, R.R.5
-
12
-
-
44249098800
-
Natural products to drugs: Natural product-derived compounds in clinical trials
-
DOI 10.1039/b514294f
-
Butler, M.S., 2008. Natural products to drugs: natural product-derived compounds in clinical trials. Nat. Prod. Rep. 25, 475-516. (Pubitemid 351725315)
-
(2008)
Natural Product Reports
, vol.25
, Issue.3
, pp. 475-516
-
-
Butler, M.S.1
-
13
-
-
20844437061
-
A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
-
DOI 10.1038/nbt1059
-
Card, G.L., Blasdel, L, England, B.P., Zhang, C, Suzuki, Y., Gillette, S., Fong, D., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.H., Schlessinger, J., Zhang, K.Y., 2005. A family of phosphodiesterase inhibitors discovered by co-crystallography and scaffold-based drug design. Nat. Biotechnol. 23, 201-207. (Pubitemid 40255330)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.2
, pp. 201-207
-
-
Card, G.L.1
Blasdel, L.2
England, B.P.3
Zhang, C.4
Suzuki, Y.5
Gillette, S.6
Fong, D.7
Ibrahim, P.N.8
Artis, D.R.9
Bollag, G.10
Milburn, M.V.11
Kim, S.-H.12
Schlessinger, J.13
Zhang, K.Y.J.14
-
14
-
-
84877959168
-
Type I interferons: Ancient peptides with still under-discovered anti-cancer properties
-
Caraglia, M., Dicitore, A., Marra, M., Castiglioni, S., Persani, L., Sperlongano, P., Tagliaferri, P., Abbruzzese, A., Vitale, G., 2013. Type I interferons: ancient peptides with still under-discovered anti-cancer properties. Protein Pept. Lett. 20, 412-423.
-
(2013)
Protein Pept. Lett.
, vol.20
, pp. 412-423
-
-
Caraglia, M.1
Dicitore, A.2
Marra, M.3
Castiglioni, S.4
Persani, L.5
Sperlongano, P.6
Tagliaferri, P.7
Abbruzzese, A.8
Vitale, G.9
-
15
-
-
69249232214
-
Emerging strategies to strengthen the anti-tumour activity of type I interferons: Overcoming survival pathways
-
Caraglia, M., Marra, M., Tagliaferri, P., Lamberts, S.W., Zappavigna, S., Misso, G., Cavagnini, F., Facchini, G., Abbruzzese, A., Hofland, L.J., Vitale, G., 2009. Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways. Curr. Cancer Drug Targets 9, 690-704.
-
(2009)
Curr. Cancer Drug Targets
, vol.9
, pp. 690-704
-
-
Caraglia, M.1
Marra, M.2
Tagliaferri, P.3
Lamberts, S.W.4
Zappavigna, S.5
Misso, G.6
Cavagnini, F.7
Facchini, G.8
Abbruzzese, A.9
Hofland, L.J.10
Vitale, G.11
-
16
-
-
0038081194
-
Identification of chelerythrine as an inhibitor of BclXL function
-
DOI 10.1074/jbc.C300138200
-
Chan, S.L., Lee, M.C., Tan, K.O., Yang, L.K., Lee, A.S., Flotow, H., Fu, N.Y, Butler, M.S., Soejarto, D.D., Buss, A.D., Yu, V.C., 2003. Identification of chelerythrine as an inhibitor of Bcl XL function. J. Biol. Chem. 278, 20453-20456. (Pubitemid 36806340)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.23
, pp. 20453-20456
-
-
Chan, S.-L.1
Lee, M.C.2
Tan, K.O.3
Yang, L.-K.4
Lee, A.S.Y.5
Flotow, H.6
Fu, N.Y.7
Butler, M.S.8
Soejarto, D.D.9
Buss, A.D.10
Yu, V.C.11
-
17
-
-
78649284256
-
Overcoming drug resistance by regulating nuclear receptors
-
Chen, T., 2010. Overcoming drug resistance by regulating nuclear receptors. Adv. Drug Delivery Rev. 62, 1257-1264.
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, pp. 1257-1264
-
-
Chen, T.1
-
18
-
-
11144311139
-
Lessons from natural molecules
-
DOI 10.1038/nature03194
-
Clardy, J., Walsh, C, 2004. Lessons from natural molecules. Nature 432, 829-837. (Pubitemid 40037138)
-
(2004)
Nature
, vol.432
, Issue.7019
, pp. 829-837
-
-
Clardy, J.1
Walsh, C.2
-
19
-
-
2942616604
-
Complex phenotypic assays in high-throughput screening
-
DOI 10.1016/j.cbpa.2004.04.002, PII S1367593104000481
-
Clemons, P.A., 2004. Complex phenotypic assays in high-throughput screening. Curr. Opin. Chem. Biol. 8, 334-338. (Pubitemid 38759409)
-
(2004)
Current Opinion in Chemical Biology
, vol.8
, Issue.3
, pp. 334-338
-
-
Clemons, P.A.1
-
20
-
-
33751106653
-
New approaches to molecular cancer therapeutics
-
DOI 10.1038/nchembio840, PII NCHEMBIO840
-
Collins, I., Workman, P., 2006. New approaches to molecular cancer therapeutics. Nat. Chem. Biol. 2, 689-700. (Pubitemid 44764211)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.12
, pp. 689-700
-
-
Collins, I.1
Workman, P.2
-
21
-
-
0035397136
-
Cytotoxicity evaluation of natural coptisine and synthesis of coptisine from berberine
-
DOI 10.1016/S0014-827X(01)01121-1, PII S0014827X01011211
-
Colombo, M.L., Bugatti, C, Mossa, A., Pescalli, N., Piazzoni, L., Pezzoni, G., Menta, E., Spinelli, S., Johnson, F., Gupta, R.C., Dasaradhi, L., 2001. Cytotoxicity evaluation of natural coptisine and synthesis of coptisine from berberine. Farmaco 56, 403-409. (Pubitemid 32622107)
-
(2001)
Farmaco
, vol.56
, Issue.5-7
, pp. 403-409
-
-
Colombo, M.L.1
Bugatti, C.2
Mossa, A.3
Pescalli, N.4
Piazzoni, L.5
Pezzoni, G.6
Menta, E.7
Spinelli, S.8
Johnson, F.9
Gupta, R.C.10
Dasaradhi, L.11
-
22
-
-
84883791012
-
Bisphosphonates and cancer: What opportunities from nanotechnology?
-
De Rosa, G., Misso, G., Salzano, G., Caraglia, M., 2013. Bisphosphonates and cancer: what opportunities from nanotechnology? J. Drug Delivery 2013, 637976.
-
(2013)
J. Drug Delivery
, vol.2013
, pp. 637976
-
-
De Rosa, G.1
Misso, G.2
Salzano, G.3
Caraglia, M.4
-
23
-
-
0037090858
-
The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death
-
DOI 10.1016/S0006-2952(02)00902-4, PII S0006295202009024
-
Ding, Z., Tang, S.C., Weerasinghe, P., Yang, X., Pater, A., Liepins, A., 2002. The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death. Biochem. Pharmacol. 63, 1415-1421. (Pubitemid 34457956)
-
(2002)
Biochemical Pharmacology
, vol.63
, Issue.8
, pp. 1415-1421
-
-
Ding, Z.1
Tang, S.-C.2
Weerasinghe, P.3
Yang, X.4
Pater, A.5
Liepins, A.6
-
24
-
-
0033955825
-
P53 alterations in human leukemia-lymphoma cell lines: In vitro artifact or prerequisite for cell immortalization?
-
Drexler, H.G., Fombonne, S., Matsuo, Y., Hu, Z.B., Hamaguchi, H., Uphoff, C.C., 2000. p53 alterations in human leukemia-lymphoma cell lines: in vitro artifact or prerequisite for cell immortalization? Leukemia 14, 198-206. (Pubitemid 30068392)
-
(2000)
Leukemia
, vol.14
, Issue.1
, pp. 198-206
-
-
Drexler, H.G.1
Fombonne, S.2
Matsuo, Y.3
Hu, Z.-B.4
Hamaguchi, H.5
Uphoff, C.C.6
-
25
-
-
77953264274
-
New method for the study of amaryllidaceae alkaloid biosynthesis using biotransformation of deuterium-labeled precursor in tissue cultures
-
El Tahchy, A., Boisbrun, M., Ptak, A., Dupire, F., Chrétien, F., Henry, M., Chapleur, Y., Laurain-Mattar, D., 2010. New method for the study of Amaryllidaceae alkaloid biosynthesis using biotransformation of deuterium-labeled precursor in tissue cultures. Acta Biochim. Pol. 57, 75-82.
-
(2010)
Acta Biochim. Pol.
, vol.57
, pp. 75-82
-
-
El Tahchy, A.1
Boisbrun, M.2
Ptak, A.3
Dupire, F.4
Chrétien, F.5
Henry, M.6
Chapleur, Y.7
Laurain-Mattar, D.8
-
26
-
-
80052441290
-
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
-
Esposito, C.L., Passaro, D., Longobardo, I., Condorelli, G., Marotta, P., Affuso, A., de Franciscis, V., Cerchia, L., 2011. A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death. PLoS One 6, e24071.
-
(2011)
PLoS One
, vol.6
-
-
Esposito, C.L.1
Passaro, D.2
Longobardo, I.3
Condorelli, G.4
Marotta, P.5
Affuso, A.6
De Franciscis, V.7
Cerchia, L.8
-
27
-
-
84861499899
-
Curcumin-from molecule to biological function
-
Esatbeyoglu, T., Huebbe, P, Ernst, I.M., Chin, D., Wagner, A.E., Rimbach, G., 2012. Curcumin-from molecule to biological function. Angew. Chem. Int. Ed. Engl. 51, 5308-5332.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 5308-5332
-
-
Esatbeyoglu, T.1
Huebbe, P.2
Ernst, I.M.3
Chin, D.4
Wagner, A.E.5
Rimbach, G.6
-
28
-
-
0037208308
-
Property distributions: Differences between drugs, natural products, and molecules from combinatorial chemistry
-
Feher, M., Schmidt, J.M., 2003. Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry. J. Chem. Inf. Comput. Sci. 43, 218-227.
-
(2003)
J. Chem. Inf. Comput. Sci.
, vol.43
, pp. 218-227
-
-
Feher, M.1
Schmidt, J.M.2
-
29
-
-
1542515338
-
A census of human cancer genes
-
Futreal, P.A., Coin, L., Marshall, M., Down, T., Hubbard, T., Wooster, R., Rahman, N, Stratton, M.R., 2004. A census of human cancer genes. Nat. Rev. Cancer 3, 177-183. (Pubitemid 38337497)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.3
, pp. 177-183
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
30
-
-
84859187259
-
Systematic identification of genomic markers of drug sensitivity in cancer cells
-
Garnett, M.J., Edelman, E.J., Heidorn, S.J., Greenman, C.D., Dastur, A., Lau, K.W., Greninger, P., Thompson, I.R., Luo, X., Soares, J., Liu, Q., Iorio, F., Surdez, D., Chen, L., Milano, R.J., Bignell, G.R., Tam, A.T., Davies, H., Stevenson, J.A., Barthorpe, S., Lutz, S.R., Kogera, F., Lawrence, K., McLaren-Douglas, A., Mitropoulos, X., Mironenko, T., Thi, H., Richardson, L., Zhou, W., Jewitt, F., Zhang, T., O'Brien, P., Boisvert, J.L., Price, S., Hur Yang, W., Deng, X., Butler, A., Choi, H.G., Chang, J.W., Baselga, J., Stamenkovic, I., Engelman, J.A., Sharma, S.V., Delattre, O., Saez-Rodriguez, J., Gray, N.S., Settleman, J., Futreal, P.A., Haber, D.A., Stratton, M.R., Ramaswamy, S., McDermott, U., Benes, C.H., 2012. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 483, 570-575.
-
(2012)
Nature
, vol.483
, pp. 570-575
-
-
Garnett, M.J.1
Edelman, E.J.2
Heidorn, S.J.3
Greenman, C.D.4
Dastur, A.5
Lau, K.W.6
Greninger, P.7
Thompson, I.R.8
Luo, X.9
Soares, J.10
Liu, Q.11
Iorio, F.12
Surdez, D.13
Chen, L.14
Milano, R.J.15
Bignell, G.R.16
Tam, A.T.17
Davies, H.18
Stevenson, J.A.19
Barthorpe, S.20
Lutz, S.R.21
Kogera, F.22
Lawrence, K.23
McLaren-Douglas, A.24
Mitropoulos, X.25
Mironenko, T.26
Thi, H.27
Richardson, L.28
Zhou, W.29
Jewitt, F.30
Zhang, T.31
O'Brien, P.32
Boisvert, J.L.33
Price, S.34
Hur Yang, W.35
Deng, X.36
Butler, A.37
Choi, H.G.38
Chang, J.W.39
Baselga, J.40
Stamenkovic, I.41
Engelman, J.A.42
Sharma, S.V.43
Delattre, O.44
Saez-Rodriguez, J.45
Gray, N.S.46
Settleman, J.47
Futreal, P.A.48
Haber, D.A.49
Stratton, M.R.50
Ramaswamy, S.51
McDermott, U.52
Benes, C.H.53
more..
-
31
-
-
19944434344
-
Identification of novel p38α MAP kinase inhibitors using fragment-based lead generation
-
DOI 10.1021/jm049575n
-
Gill, A.L., Frederickson, M., Cleasby, A., Woodhead, S.J., Carr, M.G., Woodhead, A.J., Walker, M.T., Congreve, M.S., Devine, L.A., Tisi, D., O'Reilly, M., Seavers, L.C., Davis, D.J., Curry, J., Anthony, R., Padova, A., Murray, C.W., Carr, R.A., Jhoti, H., 2005. Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation. J. Med. Chem. 48, 414-426. (Pubitemid 40139784)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.2
, pp. 414-426
-
-
Gill, A.L.1
Frederickson, M.2
Cleasby, A.3
Woodhead, S.J.4
Carr, M.G.5
Woodhead, A.J.6
Walker, M.T.7
Congreve, M.S.8
Devine, L.A.9
Tisi, D.10
O'Reilly, M.11
Seavers, L.C.A.12
Davis, D.J.13
Curry, J.14
Anthony, E.15
Padova, A.16
Murray, C.W.17
Carr, R.A.E.18
Jhoti, H.19
-
32
-
-
64249114690
-
The use of GEM models for experimental cancer therapeutics
-
Gopinathan, A., Tuveson, D.A., 2008. The use of GEM models for experimental cancer therapeutics. Dis. Model. Mech. 1, 83-86.
-
(2008)
Dis. Model. Mech.
, vol.1
, pp. 83-86
-
-
Gopinathan, A.1
Tuveson, D.A.2
-
33
-
-
84859978206
-
Use of cell-SELEX to generate DNA aptamers as molecular probes of HPV-associated cervical cancer cells
-
Graham, J.C., Zarbl, H., 2012. Use of cell-SELEX to generate DNA aptamers as molecular probes of HPV-associated cervical cancer cells. PLoS One 7, e36103.
-
(2012)
PLoS One
, vol.7
-
-
Graham, J.C.1
Zarbl, H.2
-
34
-
-
33644505182
-
Pro apoptotic activity of ukrain is based on Chelidonium majus L alkaloids and mediated via a mitochondrial death pathway
-
Habermehl, D., Kammerer, B., Handrick, R., Eldh, T., Gruber, C., Cordes, N., Daniel, P. T., Plasswilm, L, Bamberg, M., Belka, C, Jendrossek, V., 2006. Pro apoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway. BMC Cancer 17, 6-14.
-
(2006)
BMC Cancer
, vol.17
, pp. 6-14
-
-
Habermehl, D.1
Kammerer, B.2
Handrick, R.3
Eldh, T.4
Gruber, C.5
Cordes, N.6
Daniel, P.T.7
Plasswilm, L.8
Bamberg, M.9
Belka, C.10
Jendrossek, V.11
-
35
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D., Weinberg, R.A., 2011. Hallmarks of cancer: the next generation. Cell 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
36
-
-
0033104653
-
Statistical investigation into the structural complementarity of natural products and synthetic compounds
-
DOI 10.1002/(SICI)1521-3773(19990301)38:5<643::AID-ANIE643>3.0. CO;2-G
-
Henkel, T., Brunne, R., Muller, H., Reichel, F., 1999. Statistical investigation of structural complementarity of natural products and synthetic compounds. Angew. Chem. Int. Ed. Engl. 38, 643-647. (Pubitemid 29129819)
-
(1999)
Angewandte Chemie - International Edition
, vol.38
, Issue.5
, pp. 643-647
-
-
Henkel, T.1
Brunne, R.M.2
Muller, H.3
Reichel, F.4
-
37
-
-
84863035912
-
-
Howlader, N., Noone, A.M., Krapcho, M., Neyman, N., Aminou, R., Altekruse, S.F., Kosary, C.L., Ruhl, J., Tatalovich, Z., Cho, H., Mariotto, A., Eisner, M.P., Lewis, D.R., Chen, H.S., Feuer, E.J., Cronin, K.A., 2012. SEER Cancer Statistics Review.
-
(2012)
SEER Cancer Statistics Review
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
Neyman, N.4
Aminou, R.5
Altekruse, S.F.6
Kosary, C.L.7
Ruhl, J.8
Tatalovich, Z.9
Cho, H.10
Mariotto, A.11
Eisner, M.P.12
Lewis, D.R.13
Chen, H.S.14
Feuer, E.J.15
Cronin, K.A.16
-
38
-
-
0033987203
-
Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines
-
DOI 10.1016/S0304-3835(99)00264-5, PII S0304383599002645
-
Iizuka, N., Miyamoto, K., Okita, K., Tangoku, A., Hayashi, H., Yosino, S., Abe, T., Morioka, T., Hazama, S., Oka, M., 2000. Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines. Cancer Lett. 148, 19-25. (Pubitemid 30012124)
-
(2000)
Cancer Letters
, vol.148
, Issue.1
, pp. 19-25
-
-
Iizuka, N.1
Miyamoto, K.2
Okita, K.3
Tangoku, A.4
Hayashi, H.5
Yosino, S.6
Abe, T.7
Morioka, T.8
Hazama, S.9
Oka, M.10
-
39
-
-
33846563409
-
Why most published research findings are false
-
Ioannidis, J.P., 2005. Why most published research findings are false. PLoS Med. 2, e124.
-
(2005)
PLoS Med.
, vol.2
-
-
Ioannidis, J.P.1
-
40
-
-
68149142567
-
Rapid and enantiose-lective assembly of the lycorine framework using chemo-enzymatic techniques
-
Jones, M.T., Schwartz, B.D., Willis, A.C., Banwell, M.G., 2009. Rapid and enantiose-lective assembly of the lycorine framework using chemo-enzymatic techniques. Org. Lett. 11, 3506-3509.
-
(2009)
Org. Lett.
, vol.11
, pp. 3506-3509
-
-
Jones, M.T.1
Schwartz, B.D.2
Willis, A.C.3
Banwell, M.G.4
-
41
-
-
84874366062
-
P300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles
-
Kaur, J., Tikoo, K., 2013. p300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles. Biochim. Biophys. Acta 1833, 1028-1040.
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 1028-1040
-
-
Kaur, J.1
Tikoo, K.2
-
42
-
-
14944383798
-
The evolving role of natural products in drug discovery
-
DOI 10.1038/nrd1657
-
Koehn, F.E., Carter, G.T., 2005. The evolving role of natural products in drug discovery. Nat. Rev. Drug Discovery 4, 206-220. (Pubitemid 40372555)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.3
, pp. 206-220
-
-
Koehn, F.E.1
Carter, G.T.2
-
43
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
Kola, I., Landis, J., 2004. Can the pharmaceutical industry reduce attrition rates? Nat. Rev. Drug Discovery 3, 711-715. (Pubitemid 39173511)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.8
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
44
-
-
0028814733
-
Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells
-
Kuo, C.L., Chou, C.C., Yung, B.Y., 1995. Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer Lett. 93, 193-200.
-
(1995)
Cancer Lett.
, vol.93
, pp. 193-200
-
-
Kuo, C.L.1
Chou, C.C.2
Yung, B.Y.3
-
45
-
-
34247324325
-
C-Raf antagonizes apoptosis induced by IFN-α in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A
-
DOI 10.1038/sj.cdd.4402102, PII 4402102
-
Lamberti, A, Longo, O, Marra, M, Tagliaferri, P, Bismuto, E, Fiengo, A, Viscomi, C, Budillon, A, Rapp, UR, Wang, E, Venuta, S, Abbruzzese, A, Arcari, P, Caraglia, M., 2007. C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A. Cell Death. Differ. 14, 952-962. (Pubitemid 46629834)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.5
, pp. 952-962
-
-
Lamberti, A.1
Longo, O.2
Marra, M.3
Tagliaferri, P.4
Bismuto, E.5
Fiengo, A.6
Viscomi, C.7
Budillon, A.8
Rapp, U.R.9
Wang, E.10
Venuta, S.11
Abbruzzese, A.12
Arcari, P.13
Caraglia, M.14
-
46
-
-
77951143131
-
Lycorine and its derivatives for anticancer drug design
-
Lamoral-Theys, D., Decaestecker, C., Mathieu, V., Dubois, J., Kornienko, A., Kiss, R., Evidente, A., Pottier, L., 2010. Lycorine and its derivatives for anticancer drug design. Mini-Rev. Med. Chem. 10, 41-50.
-
(2010)
Mini-Rev. Med. Chem.
, vol.10
, pp. 41-50
-
-
Lamoral-Theys, D.1
Decaestecker, C.2
Mathieu, V.3
Dubois, J.4
Kornienko, A.5
Kiss, R.6
Evidente, A.7
Pottier, L.8
-
47
-
-
84876388556
-
Control of autophagic cell death by caspase-10 in multiple myeloma
-
Lamy, L., Ngo, V.N., Emre, N.C.T., Shaffer III, A.L., Yang, Y., Tian, E., Nair, V., Kruhlak, M.J., Zingone, A., Landgren, O., Staudt, L.M., 2013. Control of autophagic cell death by caspase-10 in multiple myeloma. Cancer Cell 23, 435-449.
-
(2013)
Cancer Cell
, vol.23
, pp. 435-449
-
-
Lamy, L.1
Ngo, V.N.2
Emre, N.C.T.3
Shaffer III, A.L.4
Yang, Y.5
Tian, E.6
Nair, V.7
Kruhlak, M.J.8
Zingone, A.9
Landgren, O.10
Staudt, L.M.11
-
48
-
-
33745526474
-
Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells
-
DOI 10.1016/j.canlet.2005.08.024, PII S030438350500813X
-
Letasiova, S., Jantova, S., Cipak, L., Muckova, M., 2006. Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells. Cancer Lett. 239, 254-262. (Pubitemid 43977860)
-
(2006)
Cancer Letters
, vol.239
, Issue.2
, pp. 254-262
-
-
Letasiova, S.1
Jantova, S.2
Cipak, L.3
Muckova, M.4
-
49
-
-
79958158761
-
Inhibition of cell proliferation by an anti-EGFR aptamer
-
Li, N., Nguyen, H.H., Byrom, M., Ellington, A.D., 2011. Inhibition of cell proliferation by an Anti-EGFR aptamer. PLoS One 6, e20299.
-
(2011)
PLoS One
, vol.6
-
-
Li, N.1
Nguyen, H.H.2
Byrom, M.3
Ellington, A.D.4
-
50
-
-
38849166096
-
Modeling genomic diversity and tumor dependency in malignant melanoma
-
DOI 10.1158/0008-5472.CAN-07-2615
-
Lin, W.M., Baker, A.C., Beroukhim, R., Winckler, W., Feng, W., Marmion, J.M., Laine, E., Greulich, H., Tseng, H., Gates, C., Hodi, F.S., Dranoff, G., Sellers, W.R., Thomas, R.K., Meyerson, M., Golub, T.R., Dummer, R., Herlyn, M., Getz, G., Garraway, L.A., 2008. Modeling genomic diversity and tumor dependency in malignant melanoma. Cancer Res. 68, 664-673. (Pubitemid 351206741)
-
(2008)
Cancer Research
, vol.68
, Issue.3
, pp. 664-673
-
-
Lin, W.M.1
Baker, A.C.2
Beroukhim, R.3
Winckler, W.4
Feng, W.5
Marmion, J.M.6
Laine, E.7
Greulich, H.8
Tseng, H.9
Gates, C.10
Hodi, F.S.11
Dranoff, G.12
Sellers, W.R.13
Thomas, R.K.14
Meyerson, M.15
Golub, T.R.16
Dummer, R.17
Herlyn, M.18
Getz, G.19
Garraway, L.A.20
more..
-
51
-
-
31144440676
-
Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line
-
Lin, J.P., Yang, J.S., Lee, J.H., Hsieh, W.T., Chung, J.G., 2006. Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. World J. Gastroenterol. 12, 21-28.
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 21-28
-
-
Lin, J.P.1
Yang, J.S.2
Lee, J.H.3
Hsieh, W.T.4
Chung, J.G.5
-
52
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
DOI 10.1016/S0169-409X(96)00423-1, PII S0169409X96004231
-
Lipinski, C.A., Lombardo, F., Dominy, B.W., Feeney, P.J., 1997. Experimental and computational approaches to estimate solubility and permeability in drug discovery and developmental settings. Adv. Drug Delivery Rev. 23, 3-25. (Pubitemid 27046991)
-
(1997)
Advanced Drug Delivery Reviews
, vol.23
, Issue.1-3
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
53
-
-
84865281579
-
Triphala and its active constituent chebulinic acid are natural inhibitors of vascular endothelial growth factor - A mediated angiogenesis
-
http://dx.doi.org/10.1371/journal.pone.0043934
-
Lu, K., Chakroborty, D., Sarkar, C., Lu, T., Xie, Z., Liu, Z., Basu, S., 2012. Triphala and its active constituent chebulinic acid are natural inhibitors of vascular endothelial growth factor - a mediated angiogenesis. PLoS One 7, e43934, http://dx.doi.org/10.1371/journal.pone.0043934.
-
(2012)
PLoS One
, vol.7
-
-
Lu, K.1
Chakroborty, D.2
Sarkar, C.3
Lu, T.4
Xie, Z.5
Liu, Z.6
Basu, S.7
-
54
-
-
20144388437
-
Identification of akt pathway inhibitors using redistribution screening on the FLIPR and the IN cell 3000 analyzer
-
Lundholt, B.K., Linde, V., Loechel, F., Pedersen, H.C., Moller, S., Praestegaard, M., Mikkelsen, I., Scudder, K., Bjorn, S.P., Heide, M., Arkhammar, P.O., Terry, R., Nielsen, S.J., 2005. Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer. J. Biomol. Screening 10, 20-29.
-
(2005)
J. Biomol. Screening
, vol.10
, pp. 20-29
-
-
Lundholt, B.K.1
Linde, V.2
Loechel, F.3
Pedersen, H.C.4
Moller, S.5
Praestegaard, M.6
Mikkelsen, I.7
Scudder, K.8
Bjorn, S.P.9
Heide, M.10
Arkhammar, P.O.11
Terry, R.12
Nielsen, S.J.13
-
55
-
-
33749326967
-
The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine
-
DOI 10.1007/s10565-006-0109-x
-
Malikova, J., Zdarilova, A., Hlobilkova, A., Ulrichova, J., 2006. The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell Biol. Toxicol. 22, 439-453. (Pubitemid 44488532)
-
(2006)
Cell Biology and Toxicology
, vol.22
, Issue.6
, pp. 439-453
-
-
Malikova, J.1
Zdarilova, A.2
Hlobilkova, A.3
Ulrichova, J.4
-
56
-
-
70649092075
-
Lycopodine from lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation
-
Mandal, S.K., Biswas, R., Bhattacharyya, S.S., Paul, S., Dutta, S., Pathak, S., Khuda-Bukhsh, A.R., 2010. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Eur. J. Pharmacol. 626, 115-122.
-
(2010)
Eur. J. Pharmacol.
, vol.626
, pp. 115-122
-
-
Mandal, S.K.1
Biswas, R.2
Bhattacharyya, S.S.3
Paul, S.4
Dutta, S.5
Pathak, S.6
Khuda-Bukhsh, A.R.7
-
57
-
-
0036488643
-
Natural products in cancer chemotherapy: Past, present and future
-
Mann, J., 2002. Natural products in cancer chemotherapy: past, present and future. Nat. Rev. Cancer 2, 143-148. (Pubitemid 37328801)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.2
, pp. 143-148
-
-
Mann, J.1
-
58
-
-
33644984254
-
Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells
-
Mantena, S.K., Sharma, S.D., Katiyar, S.K., 2006. Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol. Cancer Ther. 5, 296-308.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 296-308
-
-
Mantena, S.K.1
Sharma, S.D.2
Katiyar, S.K.3
-
59
-
-
50149095987
-
Diet and cancer prevention: The roles of observation and experimentation
-
Martinez, M.E., Marshall, J.R., Giovannucci, E., 2008. Diet and cancer prevention: the roles of observation and experimentation. Nat. Rev. Cancer 8, 694-703.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 694-703
-
-
Martinez, M.E.1
Marshall, J.R.2
Giovannucci, E.3
-
60
-
-
9244239811
-
G1 cell-cycle control and cancer
-
DOI 10.1038/nature03094
-
Massague, J., 2004. G1 cell-cycle control and cancer. Nature 432, 298-306. (Pubitemid 39551657)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 298-306
-
-
Massague, J.1
-
61
-
-
38049097938
-
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling
-
McDermott, U., Sharma, S.V., Dowell, L., Greninger, P., Montagut, C., Lamb, J., Archibald, H., Raudales, R., Tam, A., Lee, D., Rothenberg, S.M., Supko, J.G., Sordella, R., Ulkus, L.E., Iafrate, A.J., Maheswaran, S., Njauw, C.N., Tsao, H., Drew, L., Hanke, J.H., Ma, X.J., Erlander, M.G., Gray, N.S., Haber, D.A., Settleman, J., 2007. Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proc. Nat. Acad. Sci. U.S.A. 104, 19936-19941.
-
(2007)
Proc. Nat. Acad. Sci. U.S.A.
, vol.104
, pp. 19936-19941
-
-
McDermott, U.1
Sharma, S.V.2
Dowell, L.3
Greninger, P.4
Montagut, C.5
Lamb, J.6
Archibald, H.7
Raudales, R.8
Tam, A.9
Lee, D.10
Rothenberg, S.M.11
Supko, J.G.12
Sordella, R.13
Ulkus, L.E.14
Iafrate, A.J.15
Maheswaran, S.16
Njauw, C.N.17
Tsao, H.18
Drew, L.19
Hanke, J.H.20
Ma, X.J.21
Erlander, M.G.22
Gray, N.S.23
Haber, D.A.24
Settleman, J.25
more..
-
62
-
-
33746377987
-
Inhibitors of the HSP90 molecular chaperone: Attacking the master regulator in cancer
-
DOI 10.2174/156802606777812004
-
McDonald, E., Workman, P., Jones, K., 2006. Inhibitors of the HSP90 molecular chaperone: attacking the master regulator in cancer. Curr. Top. Med. Chem. 6, 1091-1107. (Pubitemid 44110922)
-
(2006)
Current Topics in Medicinal Chemistry
, vol.6
, Issue.11
, pp. 1091-1107
-
-
McDonald, E.1
Workman, P.2
Jones, K.3
-
63
-
-
65749095009
-
Structure activity studies on the crinane alkaloid apoptosis-inducing pharmacophore
-
McNulty, J., Nair, J.J., Bastida, J., Pandey, S., Griffin, C., 2009. Structure activity studies on the crinane alkaloid apoptosis-inducing pharmacophore. Nat. Prod. Commun. 4, 483-488.
-
(2009)
Nat. Prod. Commun.
, vol.4
, pp. 483-488
-
-
McNulty, J.1
Nair, J.J.2
Bastida, J.3
Pandey, S.4
Griffin, C.5
-
64
-
-
0027138356
-
The role of p21ras in receptor tyrosine kinase signaling
-
Medema, R.H., Bos, J.L., 1993. The role of p21ras in receptor tyrosine kinase signaling. Crit. Rev. Oncog. 4, 615-661. (Pubitemid 2002497)
-
(1993)
Critical Reviews in Oncogenesis
, vol.4
, Issue.6
, pp. 615-661
-
-
Medema, R.H.1
Bos, J.L.2
-
65
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
DOI 10.1038/nrc1779
-
Minucci, S., Pelicci, P.G., 2006. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat. Rev. Cancer 6, 38-51. (Pubitemid 43054973)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.1
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
66
-
-
0035836778
-
Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma
-
DOI 10.1016/S0304-3835(00)00710-2, PII S0304383500007102
-
Mitani, N., Murakami, K., Yamaura, T., Ikeda, T., Saiki, I., 2001. Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma. Cancer Lett. 165, 35-42. (Pubitemid 32206655)
-
(2001)
Cancer Letters
, vol.165
, Issue.1
, pp. 35-42
-
-
Mitani, N.1
Murakami, K.2
Yamaura, T.3
Ikeda, T.4
Saiki, I.5
-
67
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
DOI 10.1016/j.ccr.2006.10.008, PII S153561080600314X
-
Neve, R.M., Chin, K., Fridlyand, J., Yeh, J., Baehner, F.L., Fevr, T., Clark, L., Bayani, N., Coppe, J.P., Tong, F., Speed, T., Spellman, P.T., DeVries, S., Lapuk, A., Wang, N.J., Kuo, W.L., Stilwell, J.L., Pinkel, D., Albertson, D.G., Waldman, F.M., McCormick, F., Dickson, R.B., Johnson, M.D., Lippman, M., Ethier, S., Gazdar, A., Gray, J.W., 2006. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10, 515-527. (Pubitemid 44854747)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.-P.9
Tong, F.10
Speed, T.11
Spellman, P.T.12
DeVries, S.13
Lapuk, A.14
Wang, N.J.15
Kuo, W.-L.16
Stilwell, J.L.17
Pinkel, D.18
Albertson, D.G.19
Waldman, F.M.20
McCormick, F.21
Dickson, R.B.22
Johnson, M.D.23
Lippman, M.24
Ethier, S.25
Gazdar, A.26
Gray, J.W.27
more..
-
68
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
DOI 10.1021/np068054v
-
Newman, D.J., Cragg, G.M., 2007. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 70, 461-477. (Pubitemid 46595760)
-
(2007)
Journal of Natural Products
, vol.70
, Issue.3
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
69
-
-
70349579537
-
Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine
-
Noureini, S.K., Wink, M., 2009. Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine. World J. Gastroenterol. 15, 3603-3610.
-
(2009)
World J. Gastroenterol.
, vol.15
, pp. 3603-3610
-
-
Noureini, S.K.1
Wink, M.2
-
70
-
-
54449085540
-
Chemopreventive effects of natural dietary compounds on cancer development
-
Pan, M.H., Ho, C.T., 2008. Chemopreventive effects of natural dietary compounds on cancer development. Chem. Soc. Rev. 37, 2558-2574.
-
(2008)
Chem. Soc. Rev.
, vol.37
, pp. 2558-2574
-
-
Pan, M.H.1
Ho, C.T.2
-
71
-
-
48549105216
-
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated anti-apoptotic gene products, and potentiates apoptosis
-
Pandey, M.K., Sung, B., Kunnumakkara, A.B., Sethi, G., Chaturvedi, M.M., Aggarwal, B.B., 2008. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated anti-apoptotic gene products, and potentiates apoptosis. Cancer Res. 68, 5370-5379.
-
(2008)
Cancer Res.
, vol.68
, pp. 5370-5379
-
-
Pandey, M.K.1
Sung, B.2
Kunnumakkara, A.B.3
Sethi, G.4
Chaturvedi, M.M.5
Aggarwal, B.B.6
-
72
-
-
84864085938
-
Cancer cell response to nanoparticles: Criticality and optimality
-
Patra, H.K., Dasgupta, A.K., 2012. Cancer cell response to nanoparticles: criticality and optimality. Nanomedicine 8, 842-852.
-
(2012)
Nanomedicine
, vol.8
, pp. 842-852
-
-
Patra, H.K.1
Dasgupta, A.K.2
-
73
-
-
0034228707
-
Peptide and protein recognition by designed molecules
-
Peczuh, M.W., Hamilton, A.D., 2000. Peptide and protein recognition by designed molecules. Chem. Rev. 100, 2479-2494.
-
(2000)
Chem. Rev.
, vol.100
, pp. 2479-2494
-
-
Peczuh, M.W.1
Hamilton, A.D.2
-
74
-
-
0029924267
-
Molecular epidemiology: Insights into cancer susceptibility, risk assessment, and prevention
-
DOI 10.1093/jnci/88.8.496
-
Perera, F.P., 1996. Molecular epidemiology: insights into cancer susceptibility, risk assessment, and prevention. J. Natl. Cancer Inst. 88, 496-509. (Pubitemid 26118720)
-
(1996)
Journal of the National Cancer Institute
, vol.88
, Issue.8
, pp. 496-509
-
-
Perera, F.P.1
-
75
-
-
0032959590
-
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin
-
DOI 10.1021/jm980403y
-
Roe, S.M., Prodromou, C., O'Brien, R., Ladbury, J.E., Piper, P.W., Pearl, L.H., 1999. Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin. J. Med. Chem. 42, 260-266. (Pubitemid 29069861)
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, Issue.2
, pp. 260-266
-
-
Roe, S.M.1
Prodromou, C.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
76
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen, J.M., Jordan, C.T., 2009. The increasing complexity of the cancer stem cell paradigm. Science 324, 1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
77
-
-
84872556406
-
Anticancer steroids: Linking natural and semi-synthetic compounds
-
http://dx.doi.org/10.1039/c2np20082a
-
Salvador, J.A., Carvalho, J.F., Neves, M.A., Silvestre, S.M., Leitao, A.J., Silva, M.M., Melo, M.L., Sa E., 2012. Anticancer steroids: linking natural and semi-synthetic compounds. Nat. Prod. Rep., http://dx.doi.org/10.1039/ c2np20082a.
-
(2012)
Nat. Prod. Rep.
-
-
Salvador, J.A.1
Carvalho, J.F.2
Neves, M.A.3
Silvestre, S.M.4
Leitao, A.J.5
Silva, M.M.6
Melo, M.L.7
Sa, E.8
-
78
-
-
84870874690
-
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
-
Sebastian, C., Zwaans, B.M.M., Silberman, D.M., Gymrek, M., Goren, A., Oren Ram, L. Z., Truelove, J., Guimaraes, A.R., Toiber, D., Cosentino, C., Greenson, J.K., MacDonald, A.I., McGlynn, L., Maxwell, F., Edwards, J., Giacosa, S., Guccione, E., Weissleder, R., Bernstein, B.E., Regev, A., Shiels, P.G., Lombard, D.B., Mostoslavsky, R., 2012. The histone deacetylase SIRT6 Is a tumor suppressor that controls cancer metabolism. Cell 151, 1185-1199.
-
(2012)
Cell
, vol.151
, pp. 1185-1199
-
-
Sebastian, C.1
Zwaans, B.M.M.2
Silberman, D.M.3
Gymrek, M.4
Goren, A.5
Oren Ram, L.Z.6
Truelove, J.7
Guimaraes, A.R.8
Toiber, D.9
Cosentino, C.10
Greenson, J.K.11
MacDonald, A.I.12
McGlynn, L.13
Maxwell, F.14
Edwards, J.15
Giacosa, S.16
Guccione, E.17
Weissleder, R.18
Bernstein, B.E.19
Regev, A.20
Shiels, P.G.21
Lombard, D.B.22
Mostoslavsky, R.23
more..
-
79
-
-
0020541240
-
Enzyme inhibition. VI: Inhibition of reverse transcriptase activity by protoberberine alkaloids and structure-activity relationships
-
Sethi, M.L., 1983. Enzyme inhibition VI: inhibition of reverse transcriptase activity by protoberberine alkaloids and structure-activity relationships. J. Pharm. Sci. 72, 538-541. (Pubitemid 13092194)
-
(1983)
Journal of Pharmaceutical Sciences
, vol.72
, Issue.5
, pp. 538-541
-
-
Sethi, M.L.1
-
80
-
-
77949957365
-
Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents
-
Sharma, S.V., Haber, D.A., Settleman, J., 2010. Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents. Nat. Rev. Cancer 10, 241-253.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 241-253
-
-
Sharma, S.V.1
Haber, D.A.2
Settleman, J.3
-
81
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay, J.W., Bacchetti, S., 1997. A survey of telomerase activity in human cancer. Eur. J. Cancer 33, 787-791.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
82
-
-
0042736304
-
Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI ProteinChip platform
-
DOI 10.1016/S0006-291X(03)01520-1
-
Shiwa, M., Nishimura, Y., Wakatabe, R., Fukawa, A., Arikuni, H., Ota, H., Kato, Y., Yamori, T., 2003. Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI protein chip platform. Biochem. Biophys. Res. Commun. 309, 18-25. (Pubitemid 36999752)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.309
, Issue.1
, pp. 18-25
-
-
Shiwa, M.1
Nishimura, Y.2
Wakatabe, R.3
Fukawa, A.4
Arikuni, H.5
Ota, H.6
Kato, Y.7
Yamori, T.8
-
83
-
-
67651006061
-
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
-
Sos, M.L., Michel, K., Zander, T., Weiss, J., Frommolt, P., Peifer, M., Li, D., Ullrich, R., Koker, M., Fischer, F., Shimamura, T., Rauh, D., Mermel, C., Fischer, S., Stückrath, I., Heynck, S., Beroukhim, R., Lin, W., Winckler, W., Shah, K., LaFramboise, T., Moriarty, W.F., Hanna, M., Tolosi, L., Rahnenführer, J., Verhaak, R., Chiang, D., Getz, G., Hellmich, M., Wolf, J., Girard, L., Peyton, M., Weir, B.A., Chen, T.H., Greulich, H., Barretina, J., Shapiro, G.I., Garraway, L.A., Gazdar, A.F., Minna, J.D., Meyerson, M., Wong, K.K., Thomas, R.K., 2009. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J. Clin. Invest. 119, 1727-1740.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1727-1740
-
-
Sos, M.L.1
Michel, K.2
Zander, T.3
Weiss, J.4
Frommolt, P.5
Peifer, M.6
Li, D.7
Ullrich, R.8
Koker, M.9
Fischer, F.10
Shimamura, T.11
Rauh, D.12
Mermel, C.13
Fischer, S.14
Stückrath, I.15
Heynck, S.16
Beroukhim, R.17
Lin, W.18
Winckler, W.19
Shah, K.20
LaFramboise, T.21
Moriarty, W.F.22
Hanna, M.23
Tolosi, L.24
Rahnenführer, J.25
Verhaak, R.26
Chiang, D.27
Getz, G.28
Hellmich, M.29
Wolf, J.30
Girard, L.31
Peyton, M.32
Weir, B.A.33
Chen, T.H.34
Greulich, H.35
Barretina, J.36
Shapiro, G.I.37
Garraway, L.A.38
Gazdar, A.F.39
Minna, J.D.40
Meyerson, M.41
Wong, K.K.42
Thomas, R.K.43
more..
-
84
-
-
0033503047
-
High-performance liquid chromatographic-electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-throughput screening
-
Strege, M.A., 1999. High-performance liquid chromatographic-electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-throughput screening. J. Chromatogr. B 725, 67-68.
-
(1999)
J. Chromatogr. B
, vol.725
, pp. 67-68
-
-
Strege, M.A.1
-
85
-
-
84884676988
-
Natural products targeting autophagy via the PI3K/Akt/mTOR pathway as anticancer agents
-
Sun, H., Wang, Z., Yakisich, J.S., 2012. Natural products targeting autophagy via the PI3K/Akt/mTOR pathway as anticancer agents. Anticancer Agents Med. Chem. Decis. 24.
-
(2012)
Anticancer Agents Med. Chem. Decis.
, pp. 24
-
-
Sun, H.1
Wang, Z.2
Yakisich, J.S.3
-
86
-
-
70350459062
-
Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting rho kinase-mediated ezrin phosphorylation at threonine 567
-
Tang, F., Wang, D., Duan, C., Huang, D., Wu, Y., Chen, Y., Wang, W., Xie, C., Meng, J., Wang, L., Wu, B., Liu, S., Tian, D., Zhu, F., He, Z., Deng, F., Cao, Y., 2009. Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567. J. Biol. Chem. 284, 27456-27466.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27456-27466
-
-
Tang, F.1
Wang, D.2
Duan, C.3
Huang, D.4
Wu, Y.5
Chen, Y.6
Wang, W.7
Xie, C.8
Meng, J.9
Wang, L.10
Wu, B.11
Liu, S.12
Tian, D.13
Zhu, F.14
He, Z.15
Deng, F.16
Cao, Y.17
-
87
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry, N.A., Lazebnik, Y., 1998. Caspases: enemies within. Science 281, 1312-1316. (Pubitemid 28406817)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
88
-
-
84872197534
-
Optimizing treatment of metastatic colorectal cancer patients with anti - EGFR antibodies: Overcoming the mechanisms of cancer cell resistance
-
Troiani, T., Zappavigna, S., Martinelli, E., Addeo, S.R., Stiuso, P., Ciardiello, F., Caraglia, M., 2013. Optimizing treatment of metastatic colorectal cancer patients with anti - EGFR antibodies: overcoming the mechanisms of cancer cell resistance. Expert Opin. Biol. Ther. 13, 241-255.
-
(2013)
Expert Opin. Biol. Ther.
, vol.13
, pp. 241-255
-
-
Troiani, T.1
Zappavigna, S.2
Martinelli, E.3
Addeo, S.R.4
Stiuso, P.5
Ciardiello, F.6
Caraglia, M.7
-
89
-
-
0033047875
-
VEGFs, receptors and angiogenesis
-
DOI 10.1006/scbi.1998.0091
-
Veikkola, T., Alitalo, K., 1999. VEGFs, receptors and angiogenesis. Sem. Cancer Biol. 9, 211-220. (Pubitemid 29273837)
-
(1999)
Seminars in Cancer Biology
, vol.9
, Issue.3
, pp. 211-220
-
-
Veikkola, T.1
Alitalo, K.2
-
90
-
-
0347361638
-
Characteristic physical properties and structural fragments of marketed oral drugs
-
DOI 10.1021/jm030267j
-
Vieth, M., Siegel, M.G., Higgs, R.E., Watson, I.A., Robertson, D.H., Savin, K.A., Durst, G. L., Hipskind, P.A., 2004. Characteristic physical properties and structural fragments of marketed oral drugs. J. Med. Chem. 47, 224-232. (Pubitemid 38040506)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.1
, pp. 224-232
-
-
Vieth, M.1
Siegel, M.G.2
Higgs, R.E.3
Watson, I.A.4
Robertson, D.H.5
Savin, K.A.6
Durst, G.L.7
Hipskind, P.A.8
-
91
-
-
0031035181
-
An information-intensive approach to the molecular pharmacology of cancer
-
DOI 10.1126/science.275.5298.343
-
Weinstein, J.N., Myers, T.G., O'Connor, P.M., Friend, S.H., Fornacer Jr., A.J., Kohn, K.M., Fojo, T., Bates, S.E., Rubinstein, L.V., Anderson, N.L., Buolamwini, J.K., Osdol, W. W., van, Monks, A.P., Scudiero, D.A., Sausville, E.A., Zaharevitz, D.W., Bunow, B., Viswanadhan, V.N., Johnson, G.S., Wittes, R.E., Paull, K.D., 1997. An informationintensive approach to the molecular pharmacology of cancer. Science 275, 343-349. (Pubitemid 27051604)
-
(1997)
Science
, vol.275
, Issue.5298
, pp. 343-349
-
-
Weinstein, J.N.1
Myers, T.G.2
O'Connor, P.M.3
Friend, S.H.4
Fornace Jr., A.J.5
Kohn, K.W.6
Fojo, T.7
Bates, S.E.8
Rubinstein, L.V.9
Anderson, N.L.10
Buolamwini, J.K.11
Van Osdol, W.W.12
Monks, A.P.13
Scudiero, D.A.14
Sausville, E.A.15
Zaharevitz, D.W.16
Bunow, B.17
Viswanadhan, V.N.18
Johnson, G.S.19
Wittes, R.E.20
Paull, K.D.21
more..
-
93
-
-
76249127542
-
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells
-
Wu, Y., Sefah, K., Liu, H., Wang, R., Tan, W., 2010. DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc. Nat. Acad. Sci. U.S. A. 107, 5-10.
-
(2010)
Proc. Nat. Acad. Sci. U.S. A.
, vol.107
, pp. 5-10
-
-
Wu, Y.1
Sefah, K.2
Liu, H.3
Wang, R.4
Tan, W.5
-
94
-
-
34547931078
-
Modelling tissue morphogenesis and cancer in 3D
-
Yamada, K.M., Cukierman, E., 2007. Modelling tissue morphogenesis and cancer in 3D. Cell 130, 601-610.
-
(2007)
Cell
, vol.130
, pp. 601-610
-
-
Yamada, K.M.1
Cukierman, E.2
-
95
-
-
84872521627
-
Naked eye detection of lung cancer associated miRNA by paper based biosensing platform
-
Yildiz, U.H., Alagappan, P., Liedberg, B., 2012. Naked eye detection of lung cancer associated miRNA by paper based biosensing platform. Anal. Chem. 85, 820-824.
-
(2012)
Anal. Chem.
, vol.85
, pp. 820-824
-
-
Yildiz, U.H.1
Alagappan, P.2
Liedberg, B.3
-
96
-
-
84865574556
-
Natural compounds: Targeting pathways of autophagy as anti-cancer therapeutic agents
-
Zhang, X., Chen, L.X., Ouyang, L., Cheng, Y., Liu, B., 2012. Natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. Cell Prolif. 45, 466-476.
-
(2012)
Cell Prolif.
, vol.45
, pp. 466-476
-
-
Zhang, X.1
Chen, L.X.2
Ouyang, L.3
Cheng, Y.4
Liu, B.5
|